4,290 research outputs found

    Uncertainties in Arctic sea ice thickness and volume: new estimates and implications for trends

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    Sea ice volume has decreased in the last decades, evoked by changes in sea ice area and thickness. Estimates of sea ice area and thickness rely on a number of geophysical parameters which introduce large uncertainties. To quantify these uncertainties we use freeboard retrievals from ICESat and investigate different assumptions about snow depth, sea ice density and area. We find that uncertainties in ice area are of minor importance for the estimates of sea ice volume during the cold season in the Arctic basin. The choice of mean ice density used when converting sea ice freeboard into thickness mainly influences the resulting mean sea ice thickness, while snow depth on top of the ice is the main driver for the year-to-year variability, particularly in late winter. The absolute uncertainty in the mean sea ice thickness is 0.28 m in February/March and 0.21 m in October/November. The uncertainty in snow depth contributes up to 70% of the total uncertainty and the ice density 30–35%, with higher values in October/November. We find large uncertainties in the total sea ice volume and trend. The mean total sea ice volume is 10 120 Β± 1280 km<sup>3</sup> in October/November and 13 250 Β± 1860 km<sup>3</sup> in February/March for the time period 2005–2007. Based on these uncertainties we obtain trends in sea ice volume of &minus;1450 Β± 530 km<sup>3</sup> a<sup>&minus;1</sup> in October/November and &minus;880 Β± 260 km<sup>3</sup> a<sup>&minus;1</sup> in February/March over the ICESat period (2003–2008). Our results indicate that, taking into account the uncertainties, the decline in sea ice volume in the Arctic between the ICESat (2003–2008) and CryoSat-2 (2010–2012) periods may have been less dramatic than reported in previous studies. However, more work and validation is required to quantify these changes and analyse possible unresolved biases in the freeboard retrievals

    Therapeutic approach to idiopathic hypertrophic cardiomyopathy

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    Π˜Π΄ΠΈΠΎΠΏΠ°Ρ‚ΠΈΡ‡Π½Π°Ρ‚Π° Ρ…ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΎΡ„ΠΈΡ‡Π½Π° кардиомиопатия Π΅ рядко срСщана Π² дСтска Π²ΡŠΠ·Ρ€Π°ΡΡ‚ с висок ΠΏΠΎΡ‚Π΅Π½Ρ†ΠΈΠ°Π»Π΅Π½ риск ΠΎΡ‚ Ρ„Π°Ρ‚Π°Π»Π΅Π½ ΠΊΡ€Π°ΠΉ. ΠžΡ‚Π»ΠΈΡ‡ΠΈΡ‚Π΅Π»Π΅Π½ Π±Π΅Π»Π΅Π³ Π΅ ΠΌΠΈΠΎΠΊΠ°Ρ€Π΄Π½Π°Ρ‚Π° хипСртрофия ΠΏΡ€ΠΈ липса Π½Π° Ρ…Π΅ΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡ‡Π½Π° ΠΏΡ€ΠΈΡ‡ΠΈΠ½Π°. ΠžΡ‚ ΠΏΡŠΡ€Π²ΠΈΡ описан случай Π½Π° СкспСримСнтално Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π½Π° ΠΊΡŠΡ€ΠΌΠ°Ρ‡Π΅ ΠΏΡ€Π΅Π· 1971 Π³. Π±Π΅Ρ‚Π°-Π±Π»ΠΎΠΊΠ΅Ρ€ΠΈΡ‚Π΅ ΠΈΠΌΠ°Ρ‚ Π²ΠΎΠ΄Π΅Ρ‰Π° роля Π² ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½ΠΎΡ‚ΠΎ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ с Π²Π°Ρ€ΠΈΠ°Ρ†ΠΈΠΈ Π² Π΄ΠΎΠ·ΠΎΠ²ΠΈΡ‚Π΅ Ρ€Π΅ΠΆΠΈΠΌΠΈ. По послСдни Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π½ΠΈ Π΄Π°Π½Π½ΠΈ ΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡ‡Π½ΠΈ проучвания ΡƒΠΏΠΎΡ‚Ρ€Π΅Π±Π°Ρ‚Π° Π½Π° високи Π΄ΠΎΠ·ΠΈ Π±Π΅Ρ‚Π°-Π±Π»ΠΎΠΊΠ΅Ρ€ нСоспоримо ΠΏΠΎΠΊΠ°Π·Π²Π° Π·Π½Π°Ρ‡ΠΈΠΌ ΠΏΡ€ΠΎΡ†Π΅Π½Ρ‚ Π½Π° прСТивяСмост Π² Π΄ΡŠΠ»Π³ΠΎΡΡ€ΠΎΡ‡Π΅Π½ ΠΏΠ»Π°Π½.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²ΡΠΌΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡ‡Π΅Π½ случай Π½Π° 11-мСсСчно ΠΊΡŠΡ€ΠΌΠ°Ρ‡Π΅, ΠΊΠΎΠ΅Ρ‚ΠΎ ΠΏΠΎΡΡ‚ΡŠΠΏΠ²Π° Π² Π½Π°ΡˆΠ°Ρ‚Π° ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ° с Π΄Π°Π½Π½ΠΈ Π·Π° ΡΡŠΡ€Π΄Π΅Ρ‡Π½Π° Π½Π΅Π΄ΠΎΡΡ‚Π°Ρ‚ΡŠΡ‡Π½ΠΎΡΡ‚. ΠžΡ‚ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ‚Π΅ ΠΎΠ±Ρ€Π°Π·Π½ΠΈ изслСдвания - рСнтгСнография Π½Π° Π³Ρ€ΡŠΠ΄Π΅Π½ кош ΠΈ Схокардиография, сС установи ΠΈΠ·Ρ€Π°Π·Π΅Π½Π° симСтрична Ρ…ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΎΡ„ΠΈΡ‡Π½Π° нСобструктивна кардиомиопатия. Π—Π°ΠΏΠΎΡ‡Π½Π° сС ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½ΠΎ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ с ΠΏΡ€ΠΎΠΏΡ€Π°Π½ΠΎΠ»ΠΎΠ» Π² постСпСнно ΠΏΠΎΠΊΠ°Ρ‡Π²Π°Ρ‰Π° сС Π΄ΠΎΠ·Π° Π΄ΠΎ 5 ΠΌΠ³ / ΠΊΠ³ / 24 часа. Няколко сСдмици ΠΏΠΎ-късно ΠΏΡ€ΠΈ ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»Π½ΠΎ Схокардиографско изслСдванС сС установи Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»Π½ΠΎ ΠΏΠΎΠ΄ΠΎΠ±Ρ€Π΅Π½ΠΈΠ΅ Π² диастолната функция Π½Π° лява ΠΊΠ°ΠΌΠ΅Ρ€Π° с извСстна рСгрСсия Π² хипСртрофията Π½Π° ΠΌΠΈΠΎΠΊΠ°Ρ€Π΄Π°. ΠšΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΠΈΡ€Π°Π½ΠΎΡ‚ΠΎ ΠΏΡ€ΠΈΠ»Π°Π³Π°Π½Π΅ Π½Π° високи Π΄ΠΎΠ·ΠΈ Π±Π΅Ρ‚Π°-Π±Π»ΠΎΠΊΠ΅Ρ€ΠΈ Π±ΠΈ ΠΌΠΎΠ³Π»ΠΎ ΡΡŠΡ‰Π΅ΡΡ‚Π²Π΅Π½ΠΎ Π΄Π° ΠΏΠΎΠ΄ΠΎΠ±Ρ€ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π°Ρ‚Π° ΠΈ Π΄ΡŠΠ»Π³ΠΎΡΡ€ΠΎΡ‡Π½Π°Ρ‚Π° прСТивяСмост ΠΏΡ€ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ с ΠΈΠ΄ΠΈΠΎΠΏΠ°Ρ‚ΠΈΡ‡Π½Π° Ρ…ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΎΡ„ΠΈΡ‡Π½Π° кардиомиопатия.Idiopathic hypertrophic cardiomyopathy is a rare disease in childhood with a high potential of a lethal outcome. The hallmark of the disorder is myocardial hypertrophy that occurs in the absence of an obvious hemodynamic stimulus. Since the first case of an experimental treatment of an infant described in 1971, beta blockers have become one of the leading medication options with variations of the dose regimens. According to the current literature data and clinical trials the use of beta blockers in high doses is consistent with a high percentage of survival.We`re presenting a clinical case of an 11-month old infant, who was admitted to our clinic with symptoms of congestive cardiac failure. The chest radiography and echocardiography results showed a severe symmetric hypertrophic cardiomyopathy without an obstruction in the left ventricular outflow tract. The treatment was started with Propranolol in a titrating dose until reaching the dose of 5mg/kg/24hours. Several weeks later, echocardiography examination showed a significant improvement in the left ventricle diastolic function with some degree of regression of myocardial hypertrophy.The use of high doses of beta blockers together with the monitoring of the clinical state could improve the prognosis and survival in patients with idiopathic hypertrophic cardiomyopathy

    Supernova Ia: a Converging Delayed Detonation Wave

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    A model of a carbon-oxygen (C--O) presupernova core with an initial mass 1.33 M_\odot, an initial carbon mass fraction 0.27, and with an average mass growth-rate 5 x 10^{-7} M_\odot/yr due to accretion in a binary system was evolved from initial central density 10^9 g/cm^3, and temperature 2.05 x 10^8 K through convective core formation and its subsequent expansion to the carbon runaway at the center. The only thermonuclear reaction contained in the equations of evolution and runaway was the carbon burning reaction 12C + 12C with an energy release corresponding to the full transition of carbon and oxygen (with the same rate as carbon) into 56Ni. As a parameter we take \alpha_c - a ratio of a mixing length to the size of the convective zone. In spite of the crude assumptions, we obtained a pattern of the runaway acceptable for the supernova theory with the strong dependence of its duration on \alpha_c. In the variants with large enough values of \alpha_c=4.0 x 10^{-3} and 3.0 x 10^{-3} the fuel combustion occurred from the very beginning as a prompt detonation. In the range of 2.0 x 10^{-3} >= \alpha_c >= 3.0 x 10^{-4} the burning started as a deflagration with excitation of stellar pulsations with growing amplitude. Eventually, the detonation set in, which was activated near the surface layers of the presupernova (with m about 1.33 M_\odot) and penetrated into the star down to the deflagration front. Excitation of model pulsations and formation of a detonation front are described in detail for the variant with \alpha_c=1.0 x 10^{-3}.Comment: 13 pages, 11 figures, to appear in Astronomy Letter

    STUDIES ON CYTOMEGALOVIRAL (CMV) INFECTIONS IN NEWBORN CHILDREN

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    No abstrac

    Detrended fluctuation analysis as a statistical tool to monitor the climate

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    Detrended fluctuation analysis is used to investigate power law relationship between the monthly averages of the maximum daily temperatures for different locations in the western US. On the map created by the power law exponents, we can distinguish different geographical regions with different power law exponents. When the power law exponents obtained from the detrended fluctuation analysis are plotted versus the standard deviation of the temperature fluctuations, we observe different data points belonging to the different climates, hence indicating that by observing the long-time trends in the fluctuations of temperature we can distinguish between different climates.Comment: 8 pages, 4 figures, submitted to JSTA

    Results of investigation of muon fluxes of superhigh energy cosmic rays with X-ray emulsion chambers

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    The overall data from the investigation of the cosmic ray muon flux in the range of zenith angles (0-90) deg within the energy range (3.5 to 5.0) TeV is presented. The exposure of large X-ray emulsion chambers underground was 1200 tons. year. The data were processe using the method which was applied in the experiment Pamir and differred from the earlier applied one. The obtained value of a slope power index of the differential energy spectrum of the global muon flux is =3.7 that corresponds to the slope of the pion generation differential spectrum, gamma sub PI = 2.75 + or - .04. The analysis of the muon zenith-angular distribution showed that the contribution of rapid generation muons in the total muon flux agree the best with the value .2% and less with .7% at a 90% reliability level
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