The solar heating and cooling commercial demonstration program: Some early problems and results

The activities of the Marshall Space Flight Center of the National Aeronautics and Space Administration in the technical evaluation of proposals, contracts definitions, and program management details are defined and discussed. The significant problems were summarized in both technical and management aspects of the program. It was concluded that the program has significantly stimulated additional solar effort by the program participants. It was also concluded that the use of conventional construction industry organization with design/competitive bid procedures and standards has maintained a cost effective program

Making sense of incidents of violence and aggression: A constructivist grounded theory analysis of inpatient mental health nursing staff’s experiences

Introduction: While previous research explored nursing staff’s perceptions of violence and aggression thematically, there was a gap identified for in-depth analysis of the social processes and narratives which inform such perceptions. Aims: To explore the social processes underpinning narratives used to conceptualise violence and aggression. To identify which narratives support or threaten staff in constructing a positive professional identity. Method: Eight semi-structured interviews were completed with nursing and support staff who had worked, or currently worked in adult mental health inpatient contexts in the national health service of the United Kingdom. Analysis was conducted applying principles of constructivist grounded theory. Results: A model, ‘the impact of narratives of violence and aggression on professional identity construction’ was generated. This integrated four key theoretical codes: 1) constructing a positive nursing identity; 2) constructing the (un)deserving patient; 3) professional identity threats related to violence and aggression; and 4) mediating factors and support following violence and aggression. The theory explored the social processes which mediated the use of different narratives; and which narratives operated as protective or threating to the construction of a positive nursing identity. The theory further identified processes of support which could mitigate detrimental emotional and behavioural responses staff may experience following incidents. Narratives that contextualised violence and aggression in relation to restrictive ward environments, threat-responses, and patients’ previous experiences of trauma seemed to support empathy and understanding. Conclusion: Contextualising violence and aggression in terms of environment and distress in nursing teaching; staff training; and reflective practice may prove beneficial. Debriefs, supervisor support, and informal support from peers and senior team members seemed important following incidents. Mental health support may benefit staff whose emotional and behavioural responses to violence and aggression are acute, or long-lasting. Further research could support transferability and amplify underrepresented voices such as racialised staff

A system for aerodynamic design and analysis of supersonic aircraft. Part 1: General description and theoretical development

An integrated system of computer programs was developed for the design and analysis of supersonic configurations. The system uses linearized theory methods for the calculation of surface pressures and supersonic area rule concepts in combination with linearized theory for calculation of aerodynamic force coefficients

A computational system for aerodynamic design and analysis of supersonic aircraft. Part 1: General description and theoretical development

An integrated system of computer programs was developed for the design and analysis of supersonic configurations. The system uses linearized theory methods for the calculation of surface pressures and supersonic area rule concepts in combination with linearized theory for calculation of aerodynamic force coefficients. Interactive graphics are optional at the user's request. Schematics of the program structure and the individual overlays and subroutines are described

Hydrographic charting from LANDSAT Satellite: A comparison with aircraft imagery

The relative capabilities of two remote-sensing systems in measuring depth and, consequently, bottom contours in sandy-bottomed and sediment-laden coastal waters were determined quantitatively. The multispectral scanner (MSS), orbited on the LANDSAT-2 Satellite, and the ocean color scanner (OCS), flown on U-2 aircraft, were used. Analysis of imagery taken simultaneously indicates a potential for hydrographic charting of marine coastal and shallow shelf areas, even when water turbidity is a factor. Several of the eight optical channels examined on the OCS were found to be sensitive to depth or depth-related information. The greatest sensitivity was in OCS-4(0.544 + or - 0.012 microns) from which contours corresponding to depths up to 12m were determined. The sharpness of these contours and their spatial stability through time suggests that upwelling radiance is a measure of bottom reflectance and not of water turbidity. The two visible channels on LANDSAT's MSS were less sensitive in the discrimination of contours, with depths up to 8m in the high-gain mode (3x) determined in MSS-4(0.5 to 0.6 microns)

Aerodynamic design and analysis system for supersonic aircraft. Part 1: General description and theoretical development

An integrated system of computer programs has been developed for the design and analysis of supersonic configurations. The system uses linearized theory methods for the calculation of surface pressures and supersonic area rule concepts in combination with linearized theory for calculation of aerodynamic force coefficients. Interactive graphics are optional at the user's request. This part presents a general description of the system and describes the theoretical methods used

A system for aerodynamic design and analysis of supersonic aircraft. Part 4: Test cases

An integrated system of computer programs was developed for the design and analysis of supersonic configurations. The system uses linearized theory methods for the calculation of surface pressures and supersonic area rule concepts in combination with linearized theory for calculation of aerodynamic force coefficients. Interactive graphics are optional at the user's request. Representative test cases and associated program output are presented

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication.

A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication. A number of positive allosteric modulators (PAMs) that enhance GABA's actions on neuronal GABAA-Rs are in clinical use. Repurposing these GABAA-R PAMs to help treat diabetes is theoretically appealing because of their safety and potential to enhance the ability of GABA, secreted from ß-cells, or exogenously administered, to promote ß-cell replication and survival. Here, we show that clinically applicable GABAA-R PAMs can increase significantly INS-1 ß-cell replication, which is enhanced by exogenous GABA application. Furthermore, a GABAA-R PAM promoted human islet cell replication in vitro. This effect was abrogated by a GABAA-R antagonist. The combination of a PAM and low levels of exogenous GABA further increased human islet cell replication. These findings suggest that PAMs may potentiate the actions of GABA secreted by islet ß-cells on GABAA-Rs and provide a new class of drugs for diabetes treatment. Finally, our findings may explain a past clinical observation of a GABAA-R PAM reducing HbA1c levels in diabetic patients