Hubungan Kualitas Tidur Dengan Fungsi Kognitif Pada Lansia Di Bplu Senja Cerah Provinsi Sulawesi Utara

: Aging is a condition that's occurs in human thats not only starting from a certain time but also starts from the beginning of life. Globally the elderly population continues to increase. Globally the elderly population continues to grow. The increasing elderly is accompanied by health problems faced. Degenerative process in the elderly cause deterioration in the physical,social,and pshycologi. One of the effect of physical experienced by elderly is the occurrence of sleep disturbances and cognitive function. Purpose this study was aimed to identify clearly about relationship of sleep quality and cognitive function in elderly at BPLU Senja Cerah, North Sulawesi Province. Design research using cross sectional study which is data related to the independent variables and dependent variable that will be collected at the same time. Sampling using sampling Jenuh / Total Sampling with total sampel of 38 people. Statistical Test Results chi square with 95% (α=0,05) confidence level and p value 0,027 < 0,05 optained. Conclusion There is Relationship Sleep Quality with Cognitive Function in the elderly at BPLU Senja Cerah North Sulawesi Province

Permutation combinatorics of worldsheet moduli space

52 pages, 21 figures52 pages, 21 figures; minor corrections, "On the" dropped from title, matches published version52 pages, 21 figures; minor corrections, "On the" dropped from title, matches published versio

Necklace-Cloverleaf Transition in Associating RNA-like Diblock Copolymers

We consider a ${\rm A}_m{\rm B}_n$ diblock copolymer, whose links are capable of forming local reversible bonds with each other. We assume that the resulting structure of the bonds is RNA--like, i.e. topologically isomorphic to a tree. We show that, depending on the relative strengths of A--A, A--B and B--B contacts, such a polymer can be in one of two different states. Namely, if a self--association is preferable (i.e., A--A and B--B bonds are comparatively stronger than A--B contacts) then the polymer forms a typical randomly branched cloverleaf structure. On the contrary, if alternating association is preferable (i.e. A--B bonds are stronger than A--A and B--B contacts) then the polymer tends to form a generally linear necklace structure (with, probably, some rear side branches and loops, which do not influence the overall characteristics of the chain). The transition between cloverleaf and necklace states is studied in details and it is shown that it is a 2nd order phase transition.Comment: 17 pages, 9 figure

Statistical-mechanical lattice models for protein-DNA binding in chromatin

Statistical-mechanical lattice models for protein-DNA binding are well established as a method to describe complex ligand binding equilibriums measured in vitro with purified DNA and protein components. Recently, a new field of applications has opened up for this approach since it has become possible to experimentally quantify genome-wide protein occupancies in relation to the DNA sequence. In particular, the organization of the eukaryotic genome by histone proteins into a nucleoprotein complex termed chromatin has been recognized as a key parameter that controls the access of transcription factors to the DNA sequence. New approaches have to be developed to derive statistical mechanical lattice descriptions of chromatin-associated protein-DNA interactions. Here, we present the theoretical framework for lattice models of histone-DNA interactions in chromatin and investigate the (competitive) DNA binding of other chromosomal proteins and transcription factors. The results have a number of applications for quantitative models for the regulation of gene expression.Comment: 19 pages, 7 figures, accepted author manuscript, to appear in J. Phys.: Cond. Mat

Strings from Feynman Graph counting : without large N

A well-known connection between n strings winding around a circle and permutations of n objects plays a fundamental role in the string theory of large N two dimensional Yang Mills theory and elsewhere in topological and physical string theories. Basic questions in the enumeration of Feynman graphs can be expressed elegantly in terms of permutation groups. We show that these permutation techniques for Feynman graph enumeration, along with the Burnside counting lemma, lead to equalities between counting problems of Feynman graphs in scalar field theories and Quantum Electrodynamics with the counting of amplitudes in a string theory with torus or cylinder target space. This string theory arises in the large N expansion of two dimensional Yang Mills and is closely related to lattice gauge theory with S_n gauge group. We collect and extend results on generating functions for Feynman graph counting, which connect directly with the string picture. We propose that the connection between string combinatorics and permutations has implications for QFT-string dualities, beyond the framework of large N gauge theory.Comment: 55 pages + 10 pages Appendices, 23 figures ; version 2 - typos correcte

Addressing Small Scale Fisheries Management through Participatory Action Research (PAR), an Experience from the Philippines

This case demonstrates the potential of addressing small scale fisheries management through participatory action research (PAR) in one of the CRP 1.3/AAS sites in the Philippines. Following the iterative process of PAR, a series of focus group discussions (FGDs) to reflect on the issues and concerns of small scale fishermen (SSF) in Barangay Binitinan, Balingasag, Misamis Oriental, Philippines was carried out from February to May, 2014. This was followed by the conduct of consultative workshop among stakeholders in SSF in June 2014, the main objective of which was to develop a collective action plan for the management of said resource. The FGDs employed facilitated iteration and reflection of issues affecting various groups of small scale fishing community, while the Consultative Workshop among stakeholders used the appreciation-influence-control model of participatory stakeholder engagement (Ratner 2011).Consequently, various stakeholders of small scale fisheries begin to understand, appreciate and take actions together. A feeling of trust and confidence among them begin to develop which enabled them to craft a collective action plan on sustainable management and governance of municipal waters and fisheries resources. Aside from these outcomes, these processes led to the admission of “sahid” (beach seine) operators that they are indeed using illegal gear, that their gear would be replaced by the legal one by the Bureau of Fisheries and Aquatic Resources (BFAR), that the Law Enforcers would implement the Law and the small scale fishermen would abide the rules and would be apprehended by Law Enforcers once they violate the rules and the LGUs asking stakeholders to feedback the amendments necessary to make municipal ordinances well fitted to them. Another major outcome of these processes was the identification of research topics which the stakeholders identified to be necessary so that science-based productivity and governance decisions can be put in place. All of these activities fall within the PAR processes

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy

Development of single-molecule localization microscopy techniques has allowed nanometre scale localization accuracy inside cells, permitting the resolution of ultra-fine cell structure and the elucidation of crucial molecular mechanisms. Application of these methodologies to understanding processes underlying DNA replication and repair has been limited to defined in vitro biochemical analysis and prokaryotic cells. In order to expand these techniques to eukaryotic systems, we have further developed a photo-activated localization microscopy-based method to directly visualize DNA-associated proteins in unfixed eukaryotic cells. We demonstrate that motion blurring of fluorescence due to protein diffusivity can be used to selectively image the DNA-bound population of proteins. We designed and tested a simple methodology and show that it can be used to detect changes in DNA binding of a replicative helicase subunit, Mcm4, and the replication sliding clamp, PCNA, between different stages of the cell cycle and between distinct genetic backgrounds

Hamiltonian dynamics of the two-dimensional lattice phi^4 model

The Hamiltonian dynamics of the classical $\phi^4$ model on a two-dimensional square lattice is investigated by means of numerical simulations. The macroscopic observables are computed as time averages. The results clearly reveal the presence of the continuous phase transition at a finite energy density and are consistent both qualitatively and quantitatively with the predictions of equilibrium statistical mechanics. The Hamiltonian microscopic dynamics also exhibits critical slowing down close to the transition. Moreover, the relationship between chaos and the phase transition is considered, and interpreted in the light of a geometrization of dynamics.Comment: REVTeX, 24 pages with 20 PostScript figure