428 research outputs found
Experimental investigation of the performance of various wick configurations in single and two fluid heat pipes operating in the gravitational field
Performance of various wick configurations in single and two-fluid heat pipes operating as thermoregulatory system for space suit
Towards a Lightweight Approach for Modding Serious Educational Games: Assisting Novice Designers
Serious educational games (SEGs) are a growing segment of the education community’s pedagogical toolbox. Effectively creating such games remains challenging, as teachers and industry trainers are content experts; typically they are not game designers with the theoretical knowledge and practical experience needed to create a quality SEG. Here, a lightweight approach to interactively explore and modify existing SEGs is introduced, a toll that can be broadly adopted by educators for pedagogically sound SEGs. Novice game designers can rapidly explore the educational and traditional elements of a game, with a stress on tracking the SEG learning objectives, as well as allowing for reviewing and altering a variety of graphic and audio game elements
The Luminosity Function of Galaxies in Compact Groups
From R-band images of 39 Hickson compact groups (HCGs), we use galaxy counts
to determine a luminosity function extending to M_R=-14.0, approximately two
magnitudes deeper than previous compact group luminosity functions. We find
that a single Schechter function is a poor fit to the data, so we fit a
composite function consisting of separate Schechter functions for the bright
and faint galaxies. The bright end is best fit with M^*=-21.6 and alpha=-0.52
and the faint end with M^*=-16.1 and alpha=-1.17. The decreasing bright end
slope implies a deficit of intermediate luminosity galaxies in our sample of
HCGs and the faint end slope is slightly steeper than that reported for earlier
HCG luminosity functions. Furthermore, luminosity functions of subsets of our
sample reveal more substantial dwarf populations for groups with x-ray halos,
groups with tidal dwarf candidates, and groups with a dominant elliptical or
lenticular galaxy. Collectively, these results support the hypothesis that
within compact groups, the initial dwarf galaxy population is replenished by
"subsequent generations" formed in the tidal debris of giant galaxy
interactions.Comment: 26 pages, to be published in The Astrophysical Journal, 8 greyscale
plates (figures 1 and 2) can be retrieved at
http://www.astro.psu.edu/users/sdh/pubs.htm
Measuring diet in primary school children aged 8-11 years: validation of the Child and Diet Evaluation Tool (CADET) with an emphasis on fruit and vegetable intake.
Background/Objectives:The Child And Diet Evaluation Tool (CADET) is a 24-h food diary that measures the nutrition intake of children aged 3-7 years, with a focus on fruit and vegetable consumption. Until now CADET has not been used to measure nutrient intake of children aged 8-11 years. To ensure that newly assigned portion sizes for this older age group were valid, participants were asked to complete the CADET diary (the school and home food diary) concurrently with a 1-day weighed record. Subjects/Methods:A total of 67 children with a mean age of 9.3 years (s.d.: ± 1.4, 51% girls) participated in the study. Total fruit and vegetable intake in grams and other nutrients were extracted to compare the mean intakes from the CADET diary and Weighed record using t-tests and Pearson's r correlations. Bland-Altman analysis was also conducted to assess the agreement between the two methods. Results: Correlations comparing the CADET diary to the weighed record were high for fruit, vegetables and combined fruit and vegetables (r=0.7). The results from the Bland-Altman plots revealed a mean difference of 54 g (95% confidence interval: -88, 152) for combined fruit and vegetables intake. CADET is the only tool recommended by the National Obesity Observatory that has been validated in a UK population and provides nutrient level data on children's diets. Conclusions:The results from this study conclude that CADET can provide high-quality nutrient data suitable for evaluating intervention studies now for children aged 3-11 years with a focus on fruit and vegetable intake
Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury
OBJECTIVE:
Intestinal ischemia can quickly escalate to bowel necrosis and perforation. Transplantation of stem cells presents a novel treatment modality for this problem. We hypothesized that: human adipose-derived stromal cells (hASCs) would increase survival and mesenteric perfusion to a greater degree compared with differentiated cellular controls following ischemic intestinal injury, and improved outcomes with hASC therapy would be associated with preservation of intestinal histological and tight junction architecture, and lower levels of systemic inflammation following intestinal injury.
METHODS:
hASCs and keratinocytes (differentiated cellular control) were cultured on polystyrene flasks at 37°C in 5% CO2 in air. Adult male C57Bl6J mice were anesthetized and a midline laparotomy performed. The intestines were eviscerated, the small bowel mesenteric root identified, and intestinal ischemia was established by temporarily occluding the superior mesenteric artery for 60 min with a noncrushing vascular clamp. Following ischemia, the clamp was removed, and the intestines were returned to the abdominal cavity. Before abdominal closure, 2 million hASCs or keratinocytes in 250 μL of phosphate-buffered saline (carrier for cells and control solution) were infused into the peritoneum. Animals were allowed to recover for 12 or 24 h (perfusion, histology, cytokine, and immunofluoresence studies), or 7 days (survival studies). Intestinal perfusion was assessed by laser Doppler imaging. Intestinal tissue segments were stained with hematoxylin and eosin, as well as antibodies for the tight junction protein claudin-1. Separate aliquots of intestine, liver, and lung tissue were homogenized and assessed for inflammatory cytokines via multiplex beaded assay.
RESULTS:
Animals administered hASCs following intestinal ischemia and reperfusion (I/R) injury had significantly greater 7-day survival and better postischemic recovery of mesenteric perfusion compared with vehicle or keratinocyte therapy. hASCs also abated intestinal mucosal destruction, facilitated preservation of intestinal tight junctions, and decreased the systemic inflammatory response to injury.
CONCLUSIONS:
Human adipose-derived stromal cells improved survival and mesenteric perfusion and attenuated the mucosal damage associated with intestinal I/R injury. hASCs should be considered as a plausible cell source for novel cellular treatment plans following intestinal ischemia
Serum 25-hydroxy vitamin D levels in middle-aged women in relationship to adiposity and height trajectories over three decades
Background/Objectives:
The long-term chronology of the association between low serum concentrations of 25-hydroxy vitamin D (25(OH)D) and weight status is unclear. We examined whether lower 25(OH)D in middle-aged women drives upwards the weight, body mass index (BMI) and waist–hip ratio (WHR) over the next 32 years, and whether higher 25(OH)D might predict less decline in the mid- to late-life height trajectory.
Subjects/Methods:
The Population Study of Women in Gothenburg started in 1968–1969 (the baseline) in 38–60-year-old women residing in Gothenburg, Sweden. Anthropometric measures were taken at baseline and 4 re-examinations until 2000–2003. Levels of 25(OH)D were analyzed in serum stored since baseline in 1227 (84%) women. Repeated measures analyses were used to model associations between 25(OH)D (dichotomized, cut point 51.45 nmol/l) at baseline and anthropometric trajectories, adjusting for fixed and time-dependent covariates.
Results:
At baseline, mean BMI was 25.2 kg/m2 in women with low 25(OH)D and 23.8 kg/m2 in the remaining women (P<0.001), but this difference did not increase over 32 years and longitudinal differences were explained by the baseline BMI. Similar results were observed for weight and WHR. In contrast, no association was seen for height at baseline or longitudinally.
Conclusions:
No relationship was observed between 25(OH)D height trajectory, but lower 25(OH)D was associated with higher BMI, weight and WHR differences that were maintained over three decades. This provides no evidence for the direction of causality, but for a life-long difference in adiposity-related measures according to the 25D level in middle-aged women
Relationship between perception of emotional home atmosphere and fruit and vegetable consumption in European adolescents: Results from the I.Family survey
Objective: Consumption of fruits and vegetables (F&V) among adolescents falls below recommendations in many Western countries. The impact of social and emotional aspects of family life on adolescent dietary behaviour may contribute to this, yet remains under-investigated. The present study examines the association between adolescents'' perceptions of emotional home atmosphere (EHA) and their F&V consumption frequency.
Design: An FFQ was used to assess F&V consumption frequency. EHA was assessed by an eight-item measure with three subscales: Perceived home warmth, strictness and relational tension. EHA subscales were used as binary variables: A score equal to or above the median value was considered as a higher perception, while a score below the median was considered as a lower perception of the EHA in question. Country differences in meeting the European 5-a-day recommendations were described. Further, the association between EHA and F&V consumption frequency was investigated using multiple linear regression.
Setting: Regional examination centres in eight European countries.
Participants: Adolescents (n 3196) aged 12-18 years.
Results: The mean F&V consumption frequency was 3·27 (sd 2·84) times/d. Only 16·1 % of boys and 18 % of girls in our study sample met the recommendation of five F&V daily. After controlling for age, sex, education level of the parents and country of origin, perceived home warmth was associated with a 16 (95 % CI 9, 22) % higher F&V consumption frequency (P < 0·001).
Conclusions: F&V consumption frequency was suboptimal in the survey areas. Interventions targeting perceived warmth as a component of EHA could potentially have a positive effect on adolescents'' dietary behaviour
Conjunctival mucous membrane colour as an indicator for the targeted selective treatment of haemonchosis and of the general health status of peri-urban smallholder goats in southern Malawi.
Identifying Old Tidal Dwarf Irregulars
We examine the observational consequences of the two possible origins for
irregular galaxies: formation from collapse of a primordial cloud of gas early
in the age of the Universe, and formation from tidal tails in an interaction
that could have occured any time in the history of the Universe. Because the
formation from tidal tails could have occurred a long time ago, proximity to
larger galaxies is not sufficient to distinguish tidal dwarfs from traditional
dwarfs. We consider the effects of little or no dark matter on rotation speeds
and the Tully-Fisher relationship, the metallicity-luminosity relationship,
structure, and stellar populations. From these selection criteria, we identify
a small list of dwarf irregular galaxies that are candidates for having formed
as tidal dwarfs.Comment: ApJ, to appear September 20, 200
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