Chemical Utilization of Aspen

Chemical utilization of raw materials depends largely on the chemical composition and the chemical and physical properties of the raw materials under consideration. The utilization of wood is no exception to this principle. Thus, a wood having a low percentage of cellulose is uneconomical as a source of wood sugar or pulp for paper; and one of an excessively knotty character is undesirable for chemical conversion Woods having several undesirable characteristics generally fall within the classification of species little used for the purpose. Fortunate! aspen falls outside this class

Social Isolation and Weapon Use in Intimate Partner Violence Incidents in Rural Areas

This study relies on the concept of social isolation to analyze variation in weapon use in intimate partner violence (IPV) cases in rural North Carolina. Social isolation and IPV weapon use are operationalized through census and IPV incident data collected in three rural counties in southeastern North Carolina. The authors relied on reports of IPV from law enforcement agencies within these counties, which were geocoded by address and located within census tracts to assess IPV weapon use and its correlates across sub-county areas. The current study expands on studies of weapon use and social isolation by criminologists and public health researchers by assessing the nature of IPV incidents, accounting for possible incident-level and contextual correlates. Statistical analyses indicate that sex of the attacker (female) and age are the only significant predictors of weapon use. We discuss the implications of these findings for further research on weapon use and IPV in rural areas

Initial assessment and treatment of refugees in the Mediterranean Sea (a secondary data analysis concerning the initial assessment and treatment of 2656 refugees rescued from distress at sea in support of the EUNAVFOR MED relief mission of the EU)

Excerpt of the underlying study variables with explanations and degree. (DOCX 100 kb

Does the Constitution Provide More Ballot Access Protection for Presidential Elections Than for U.S. House Elections?

Both the U.S. Constitution and The Federalist Papers suggest that voters ought to have more freedom to vote for the candidate of their choice for the U.S. House of Representatives than they do for the President or the U.S. Senate. Yet, strangely, for the last thirty-three years, the U.S. Supreme Court and lower courts have ruled that the Constitution gives voters more freedom to vote for the candidate of their choice in presidential elections than in congressional elections. Also, state legislatures, which have been writing ballot access laws since 1888, have passed laws that make it easier for minor-party and independent candidates to get on the ballot for President than for the U.S. House. As a result, voters in virtually every state invariably have far more choices on their general election ballots for the President than they do for the House. This Article argues that the right of a voter to vote for someone other than a Democrat or a Republican for the House is just as important as a voter’s right to do so for President, and that courts should grant more ballot access protection to minor-party and independent candidates for the House

Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Study Group

Background: Primary diffuse large B-cell lymphoma (DLBCL) of breast is rare. We aimed to define clinical features, prognostic factors, patterns of failure, and treatment outcomes. Patients and methods: A retrospective international study of 204 eligible patients presenting to the International Extranodal Lymphoma Study Group-affiliated institutions from 1980 to 2003. Results: Median age was 64 years, with 95% of patients presenting with unilateral disease. Median overall survival (OS) was 8.0 years, and median progression-free survival 5.5 years. In multifactor analysis, favourable International Prognostic Index score, anthracycline-containing chemotherapy, and radiotherapy (RT) were significantly associated with longer OS (each P ≤ 0.03). There was no benefit from mastectomy, as opposed to biopsy or lumpectomy only. At a median follow-up time of 5.5 years, 37% of patients had progressed—16% in the same or contralateral breast, 5% in the central nervous system, and 14% in other extranodal sites. Conclusions: The combination of limited surgery, anthracycline-containing chemotherapy, and involved-field RT produced the best outcome in the pre-rituximab era. A prospective trial on the basis of these results should be pursued to confirm these observations and to determine whether the impact of rituximab on the patterns of relapse and outcome parallels that of DLBCL presenting at other site

Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS) – novel predictors for response and survival in gastric cancer patients

To evaluate the predictive value of a panel of gene polymorphisms involved in metabolism of 5-FU and cisplatin on clinical outcome in advanced gastric cancer patients. A total of 52 patients were enrolled in this study. DNA was extracted from paraffin-embedded tumour specimen. Genotypes were determined using PCR-RFLP. Median survival time was 6.0 months (95% CI 3.9;8.1). Overall response rate was 26%. Patients possessing the glutathione S-transferase P1-105 Valine/Valine (GSTP1-105VV) genotype showed a response rate of 67% compared to 21% in patients harbouring at least one GSTP1-105 Isoleucine (GSTP1-105I) allele (P=0.038). GSTP1-105VV patients demonstrated a significant superior median survival time of 15.0 months (95% CI 7.8;22.0) compared to 6.0 months (95% CI 5.1;7.0) in patients with at least one GSTP1-105I allele (P=0.037). Patients possessing a favourable thymidylate synthase (TS) genotype (2R/2R, 2R/3RC, 3RC/3RC) experienced a superior survival time of 10.2 months (95% CI 5.1;15.3) compared to 6.0 months (95% CI 5.0;7.0) in patients with unfavourable TS genotypes (P=0.099). Patients harbouring the GSTP1-105II genotype and one of the unfavourable TS genotypes showed an inferior median survival time of 6.0 months (95% CI 3.9;8.1) compared to 11 months (95% CI 6,23;15,77) in patients with either GSTP1-105VV or a favourable TS genotype (P=0.044). Testing for TS and GSTP1 polymorphisms may allow identification of gastric cancer patients who will benefit from 5-FU/cisplatin chemotherapy, sparing others the side effects of this chemotherapy

Pretreatment with Ultrasonic Energy—Its Effect Upon Volumetric Shrinkage of Redwood

Redwood heartwood samples 1.2 inches in cross section were subjected to ultrasonic irradiation prior to oven-drying. There was a small but consistent reduction in volumetric shrinkage due to the pretreatment when the test cell was subjected to continuous vacuum during irradiation. It is believed that cavitation of the wood liquid was responsible for the effect. However, since the sample moisture contents were considerably less than the maximum moisture content for redwood, the effect was evidently due to something other than the elimination of Tiemann liquid tension stress. It is suggested that the denaturing is of the kind, but not to the extent, of that believed to occur in the freezing of wet redwood