DNA waves and water

Some bacterial and viral DNA sequences have been found to induce low frequency electromagnetic waves in high aqueous dilutions. This phenomenon appears to be triggered by the ambient electromagnetic background of very low frequency. We discuss this phenomenon in the framework of quantum field theory. A scheme able to account for the observations is proposed. The reported phenomenon could allow to develop highly sensitive detection systems for chronic bacterial and viral infections.Comment: Invited talk at the DICE2010 Conference, Castiglioncello, Italy September 201

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics.

BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children, and its life-threatening risks. Italian Society of Pediatrics recently issued a guideline on the management of acute asthma attack in children over age 2, in ambulatory and emergency department settings. METHODS: The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology was adopted. A literature search was performed using the Cochrane Library and Medline/PubMed databases, retrieving studies in English or Italian and including children over age 2 year. RESULTS: Inhaled ß2 agonists are the first line drugs for acute asthma attack in children. Ipratropium bromide should be added in moderate/severe attacks. Early use of systemic steroids is associated with reduced risk of ED visits and hospitalization. High doses of inhaled steroids should not replace systemic steroids. Aminophylline use should be avoided in mild/moderate attacks. Weak evidence supports its use in life-threatening attacks. Epinephrine should not be used in the treatment of acute asthma for its lower cost / benefit ratio, compared to β2 agonists. Intravenous magnesium solphate could be used in children with severe attacks and/or forced expiratory volume1 (FEV1) lower than 60% predicted, unresponsive to initial inhaled therapy. Heliox could be administered in life-threatening attacks. Leukotriene receptor antagonists are not recommended. CONCLUSIONS: This Guideline is expected to be a useful resource in managing acute asthma attacks in children over age 2

Reaping the benefits of microorganisms in cropping systems: Is the regulatory policy adequate?

Within food plant cropping systems, microorganisms provide vital functions and ecosystem services, such as biological pest and disease control, promotion of plant growth and crop quality, and biodegradation of organic matter and pollutants. The beneficial effects of microorganisms can be achieved and/or enhanced by agricultural management measures that target the resident microbial biodiversity or by augmentation with domesticated and propagated microbial strains. This study presents a critical review of the current legislation and regulatory policies pertaining to the utilization of plant-beneficial microorganisms in the European Union (EU). For augmentative approaches, the nature of the intended effect and the product claim determine how a microbiological product is categorized and regulated, and pre-market authorization may be mandatory. Typically, microbial products have been incorporated into frameworks that were designed for evaluating non-living substances, and are therefore not well suited to the specific properties of live microorganisms. We suggest that regulatory harmonization across the sector could stimulate technical development and facilitate implementation of crop management methods employing microorganisms. Possible scenarios for regulatory reform in the longer term are discussed, but more investigation into their feasibility is needed. The findings of this study should serve as a catalyst for more efficient future use of plant-beneficial microorganisms, to the benefit of agriculture as well as the environment

Adoption of robotic assisted partial nephrectomies: a population-based analysis of U.S. surgeons from 2004-2013

The advent of minimally invasive and robotic techniques has resulted in the rapid adoption of this novel technology, with the field of urology at the forefront. Since the first Robotic‐Assisted Laparoscopic Radical Prostatectomy (RALP) was performed in 2000 using  the da Vinci Surgical System (Intuitive Surgical, Inc., Sunnyvale, CA, USA), surgeons have rapidly incorporated robotic technology for the use of radical prostatectomies for prostatic carcinoma. Prior to 2005, only a minority of surgeons‐‐fewer than 2.5%‐‐performing radical  prostatectomies utilized robotic assistance.  However, robotic assistance has become the predominant approach for radical prostatectomies, increasing from 22% to 85% between the years 2002 to 2013, representing a nearly five‐fold increase in utilization

Two prototypes for medium rotation forestry harvesting

Five years old poplar (Populus spp.) plantation represents an interesting model of productivity. The most attractive characteristics of this energy crop are the handling flexibility, the high yield of biomass per area unit and the good quality of the chips obtainable. The mechanical harvesting of five-years old poplar plantations requires the use of specialized forest machineries such as harvester, feller, forwarder and chipper. Usually, after felling, the working phases consist of extraction, stacking and chipping. Generally, the last one is carried out in a “static phase”, where the product is taken from staked logs by using a hydraulic arm having a gripper that feed the chipping machine. In order to introduce technological innovations for the medium rotation forestry harvesting, the Consiglio per la Ricerca e la sperimentazione in Agricoltura, Unità di ricerca per l’Ingegneria agraria (CRAING) of Monterotondo (Rome, Italy) has developed a five years poplar cutwindrower and a self-propelled chipper equipped with a pick up system. The prototype of cut-windrower is a semi-trailed machine powered by a 95 kW tractor (at least). It mounts a cutting system and a double pincer with variable positioning. During the cutting phase the plant is grasped by the double pincer which conveys and unloads the stem along the inter-row. The trees are placed parallel to the progress of the tractor, but oriented in the opposite direction. The biomass windrowed is then chipped in a dynamic phase directly from the inter row using the self-propelled chipper equipped with the pick-up head. In the first tests, the cut-windrower has reached an operative working capacity of 0.22 ha h-1, with an operative production of 44 t h-1. On the other hand, the self-propelled chipper has showed an operative working capacity equal to 0.18 ha h-1, and an operative production of 35 t h-1 about. Both machines have shown good quality of the work performed and the results obtained indicates that the work phases could be simplified in order to reduce both the time of use and the harvesting costs

K-string tensions at finite temperature and integrable models

It has recently been pointed out that simple scaling properties of Polyakov correlation functions of gauge systems in the confining phase suggest that the ratios of k-string tensions in the low temperature region is constant up to terms of order T^3. Here we argue that, at least in a three-dimensional Z_4 gauge model, the above ratios are constant in the whole confining phase. This result is obtained by combining numerical experiments with known exact results on the mass spectrum of an integrable two-dimensional spin model describing the infrared behaviour of the gauge system near the deconfining transition.Comment: 22 pages, 7 figures, 1 tabl

Quantum broadening of k-strings in gauge theories

We study the thickness of the confining flux tube generated by a pair of sources in higher representations of the gauge group. Using a simple geometric picture we argue that the area of the cross-section of the flux tube, as measured by a Wilson loop probe, grows logarithmically with source separation, as a consequence of the quantum fluctuations of the underlying k-string. The slope of the logarithm turns out to be universal, i.e. it is the same for all the representations and all the gauge theories. We check these predictions in a 3D Z_4 lattice gauge model by comparing the broadening of the 1-string and the 2-string.Comment: 15 pages, 5 figure

Recurrent respiratory infections between immunity and atopy

Recurrent respiratory infections (RRIs) are frequent in children and are characterized by more than 6 airway infections in 1 year or more than 1 upper airway infection per month in the period between September and April or more than 3 lower airway infections in 1 year. Often pediatric RRIs are related to predisposing factors, such as reduced airway size, poor tussive reflex, and immaturity of the immune system. RRIs due to immature immune system are a transient condition, with spontaneous resolution in the school age. However, some RRIs are expression of more complex diseases. Red flags are the onset of symptoms in the first year of life, the involvement of other systems, unusual pathogens, slowing of growth, severe infections of the lower airways, and recurrence of the infection site. To help the pediatrician in the RRI differential diagnosis, we have created a roadmap based on scientific literature data and clinical practice that identifies 6 macro areas: immunodeficiencies, simple minimal genetic immunodeficiency, atopy, obesity, nutritional deficiencies, autoinflammatory diseases, and complex diseases

Conformational Disorder Analysis of the Conditionally Disordered Protein CP12 from Arabidopsis thaliana in Its Different Redox States

CP12 is a redox-dependent conditionally disordered protein universally distributed in oxygenic photosynthetic organisms. It is primarily known as a light-dependent redox switch regulating the reductive step of the metabolic phase of photosynthesis. In the present study, a small angle X-ray scattering (SAXS) analysis of recombinant Arabidopsis CP12 (AtCP12) in a reduced and oxidized form confirmed the highly disordered nature of this regulatory protein. However, it clearly pointed out a decrease in the average size and a lower level of conformational disorder upon oxidation. We compared the experimental data with the theoretical profiles of pools of conformers generated with different assumptions and show that the reduced form is fully disordered, whereas the oxidized form is better described by conformers comprising both the circular motif around the C-terminal disulfide bond detected in previous structural analysis and the N-terminal disulfide bond. Despite the fact that disulfide bridges are usually thought to confer rigidity to protein structures, in the oxidized AtCP12, their presence coexists with a disordered nature. Our results rule out the existence of significant amounts of structured and compact conformations of free AtCP12 in a solution, even in its oxidized form, thereby highlighting the importance of recruiting partner proteins to complete its structured final folding