Harpur Palate, Volume 4 Issue 2, Winter 2005

Contributors: Gail Waldstein | Ryan G. Van Cleave | John W. Evans | J. Lorraine Brown | Maria Fire | Roy Kesey | Marvin Bell | George Tucker | Stan Sanvel Rubin | Kara D\u27Angelo | Travis Gearhart | Lee K. Abbott | Kristin Abraham | Jonathan Crimmins | Anne Keefe | Dani Rado | Sascha Feinstein | Ronald F. Currie, Jr. | Hal Sirowitz | Matthew Byrne | Sue William Silverman | Michael Hettich | Bruce Holland Rogers | Grace Cavalieri | Ron McFarland | Dara Cerv | Raymond P. Hammond | Doug Ramspeck | R. L. Futrell | Francine M. Tolf | Shane Seely | Candace Black | Russell Rowland | Joan Connor

The Bering Sea ice cover during March 1979: Comparison of surface and satellite data with the Nimbus-7 SMMR

During March 1979, field operations were carried out in the Marginal Ice Zone (MIZ) of the Bering Sea. The field measurements which included oceanographic, meteorological and sea ice observations were made nearly coincident with a number of Nimbus-7 and Tiros-N satellite observations. The results of a comparison between surface and aircraft observations, and images from the Tiros-N satellite, with ice concentrations derived from the microwave radiances of the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) are given. Following a brief discussion of the field operations, including a summary of the meteorological conditions during the experiment, the satellite data is described with emphasis on the Nimbus-7 SMMR and the physical basis of the algorithm used to retrieve ice concentrations

Management del paziente con diarrea, nausea e vomito, malnutrizione e malattia celiaca: lo stato dell'arte

MANAGEMENT DEL PAZIENTE CON DIARREA, NAUSEA E VOMITO: DALLE EVIDENZE ALLA PRATICA CLINICA La gestione del paziente con diarrea: razionale e obiettivi T.M. Attardo, C. Quarneti, R. Menichella, E. Romualdi La gestione del paziente con nausea e vomito: razionale e obiettivi T.M. Attardo, R. Menichella, C. Quarneti, E. Romualdi MALNUTRIZIONE E MALATTIA CELIACA: LO STATO DELL’ARTE La gestione del paziente con malnutrizione: dalle evidenze alla pratica clinica S. Ciarla, M. Poggiano, P. Gnerre, F. Risaliti, L. Magni, L. Morbidoni, A. Maffettone, A. Paradiso, M. Rondana, A. Schimizzi, R. Risicato La gestione del paziente con malattia celiaca: razionale e obiettivi T.M. Attardo, E. Magnani, C. Casati, D. Cavalieri, P. Crispino, F. Fascì Spurio, S. De Carli, D. Tirotta, P. Gnerr

A geometric perspective on the piecewise polynomiality of double Hurwitz numbers

We describe double Hurwitz numbers as intersection numbers on the moduli space of curves. Assuming polynomiality of the Double Ramification Cycle (which is known in genera 0 and 1), our formula explains the polynomiality in chambers of double Hurwitz numbers, and the wall crossing phenomenon in terms of a variation of correction terms to the {\psi} classes. We interpret this as suggestive evidence for polynomiality of the Double Ramification Cycle.Comment: 15 pages, 5 figure

Hodge-type integrals on moduli spaces of admissible covers

We study Hodge Integrals on Moduli Spaces of Admissible Covers. Motivation for this work comes from Bryan and Pandharipande's recent work on the local GW theory of curves, where analogouos intersection numbers, computed on Moduli Spaces of Relative Stable Maps, are the structure coefficients for a Topological Quantum Field Theory. Admissible Covers provide an alternative compactification of the Moduli Space of Maps, that is smooth and doesn't contain boundary components of excessive dimension. A parallel, yet different, TQFT, can then be constructed. In this paper we compute, using localization, the relevant Hodge integrals for admissible covers of a pointed sphere of degree 2 and 3, and formulate a conjecture for general degree. In genus 0, we recover the well-known Aspinwall Morrison formula in GW theory.Comment: This is the version published by Geometry & Topology Monographs on 21 September 200

Systems biology approach for the identification of genetic determinants of colony morphology switch in natural S. cerevisiae strain

9openColony morphology is a fascinating phenotype described in unicellular organisms as a possible step towards multicellularity. The spreading of filamentous structures is used by some pathogenic fungi, as Candida albicans, to invade human tissues thus causing infection. This phenotype, rarely observed in Saccharomyces cerevisiae colonies, is present in heterozygosis in the M28 S. cerevisiae strain, isolated from damaged grapes of the Montalcino area (Italy). Meiotic segregants of M28 show mendelian inheritance of colony morphology, thus making this strain the best suitable model to study the genetic determinants of structured colonies (filigreed). We analyzed cellular and colony morphology of M28 meiotic segregants in several different carbon sources. The addition of ethanol as the only carbon source lead to an increase in filamentation: in this perspective the stable and uniform morphotype, induced by ethanol, could reflect an adaptation to stress. In order to investigate the correlation between invasiveness, filamentous morphotype and pseudohyphal growth in S. Cerevisiae, we assessed the ability of this natural strain to invade solid media. Transcriptional analysis by means of microarrays on cells grown in fermentable and not-fermentable carbon sources and Functional Enrichment Analysis identified the genes involved in the regulation of colony morphogenesis. Our results support the hypothesis of an ecological function of filamentous phenotype in creating a community adaptable to the shifts of the environmental conditions. Whole genome comparative analysis on 12 M28 sporal derivatives of three different tetrads, with Next-Generation Sequencing (NGS) approach, allowed to discover mutations in genes candidate to be the genetic determinants of the colony morphology phenotype. We demonstrate that a number of three tetrads is sufficient to map a genetic trait with mendelian inheritance. RNA-seq based transcriptomics on the all M28 sequenced genome allowed to identify a gene expression profile associated to the filamentous morphotype and to confirm the candidate morphogenesis regulatory genesopenCappelletti, V.; Stefanini, I.; Bernà, L.; Ramazzotti, M.; Cestaro, A.; Gut, I.; Kapushesky, M.; Csikász Nagy, A.; Cavalieri, D.Cappelletti, V.; Stefanini, I.; Bernà, L.; Ramazzotti, M.; Cestaro, A.; Gut, I.; Kapushesky, M.; Csikász Nagy, A.; Cavalieri, D