425 research outputs found
Assessing suicide risk in patients with obsessive-compulsive disorder: a dimensional approach
Objectives: Although an association has been found recently between obsessive-compulsive disorder and an increased risk of suicide, the prevalence of both suicidal ideation and attempts vary considerably and are generally assessed categorically. Our aims were to evaluate the prevalence of suicidal ideation and behaviors using a dimensional approach. Methods: The sample included 129 patients with obsessive-compulsive disorder. Suicidality was assessed by administering the Columbia-Suicide Severity Rating Scale. Logistic and linear regres-sions were used to examine predictors of suicidal ideation, severe suicidal ideation, and suicidal behavior. Results: The lifetime prevalence of suicidal ideation and behaviors were 64.3% and 16.3%, respectively. Lifetime suicidal ideation was associated with the number of stressful life events, duration of illness, Hamilton Rating Scale for Depression scores, and family history of mood disorders. A family history of obsessive-compulsive disorder was associated with a lower probability of lifetime suicidal ideation. Severe suicidal ideation was related to greater severity of the most stressful life event, Hamilton Rating Scale for Depression scores, and longer duration of untreated illness. The probability of lifetime suicidal behavior was related to Hamilton Rating Scale for Anxiety scores, symmetry obsessions, and washing and checking compulsions. The probability of lifetime non-suicidal self-injurious behaviors was related to Hamilton Rating Scale for Anxiety scores. Conclusions: Recognizing predictors of suicidal ideation/behavior is crucial to identifying patients at greater risk
Supporting researchers conducting qualitative research into sensitive, challenging, and difficult topics: Experiences and practical applications.
Qualitative researchers often engage in work addressing challenging, difficult, or sensitive topics and are consequently exposed to the participants’ narratives which may be emotionally charged, distressing, or compromising. These narratives occasionally rest heavy on a researcher’s conscience or may linger in the mind. Much literature has assessed how best to keep participants safe, but less attention has been given to how we keep researchers safe. We therefore document the following: (1) Our experiences of the issues presented by undertaking qualitative research involving challenging, difficult, or sensitive topics; and (2) Practical principles devised to overcome these issues, ensuring safety and wellbeing amongst researchers engaging in these types of qualitative research. We provide guidance for qualitative researchers of all levels of experience and expertise on how best to protect and support themselves, their colleagues, and other collaborating research staff, when undertaking qualitative research which might otherwise feel uncomfortable or overwhelming to tackle
Inhomogeneous non-Gaussianity
We propose a method to probe higher-order correlators of the primordial
density field through the inhomogeneity of local non-Gaussian parameters, such
as f_NL, measured within smaller patches of the sky. Correlators between
n-point functions measured in one patch of the sky and k-point functions
measured in another patch depend upon the (n+k)-point functions over the entire
sky. The inhomogeneity of non-Gaussian parameters may be a feasible way to
detect or constrain higher-order correlators in local models of
non-Gaussianity, as well as to distinguish between single and multiple-source
scenarios for generating the primordial density perturbation, and more
generally to probe the details of inflationary physics.Comment: 16 pages, 2 figures; v2: Minor changes and references added. Matches
the published versio
Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients
Peer reviewe
The Universal One-Loop Effective Action
We present the universal one-loop effective action for all operators of
dimension up to six obtained by integrating out massive, non-degenerate
multiplets. Our general expression may be applied to loops of heavy fermions or
bosons, and has been checked against partial results available in the
literature. The broad applicability of this approach simplifies one-loop
matching from an ultraviolet model to a lower-energy effective field theory
(EFT), a procedure which is now reduced to the evaluation of a combination of
matrices in our universal expression, without any loop integrals to evaluate.
We illustrate the relationship of our results to the Standard Model (SM) EFT,
using as an example the supersymmetric stop and sbottom squark Lagrangian and
extracting from our universal expression the Wilson coefficients of
dimension-six operators composed of SM fields.Comment: 30 pages, v2 contains additional comments and corrects typos, version
accepted for publication in JHE
Signal yields, energy resolution, and recombination fluctuations in liquid xenon
This work presents an analysis of monoenergetic electronic recoil peaks in
the dark-matter-search and calibration data from the first underground science
run of the Large Underground Xenon (LUX) detector. Liquid xenon charge and
light yields for electronic recoil energies between 5.2 and 661.7 keV are
measured, as well as the energy resolution for the LUX detector at those same
energies. Additionally, there is an interpretation of existing measurements and
descriptions of electron-ion recombination fluctuations in liquid xenon as
limiting cases of a more general liquid xenon re- combination fluctuation
model. Measurements of the standard deviation of these fluctuations at
monoenergetic electronic recoil peaks exhibit a linear dependence on the number
of ions for energy deposits up to 661.7 keV, consistent with previous LUX
measurements between 2-16 keV with H. We highlight similarities in liquid
xenon recombination for electronic and nuclear recoils with a comparison of
recombination fluctuations measured with low-energy calibration data.Comment: 11 pages, 12 figures, 3 table
Physics at a 100 TeV pp collider: beyond the Standard Model phenomena
This report summarises the physics opportunities in the search and study of
physics beyond the Standard Model at a 100 TeV pp collider.Comment: 196 pages, 114 figures. Chapter 3 of the "Physics at the FCC-hh"
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