273 research outputs found
Excitation Spectrum Gap and Spin-Wave Stiffness of XXZ Heisenberg Chains: Global Renormalization-Group Calculation
The anisotropic XXZ spin-1/2 Heisenberg chain is studied using
renormalization-group theory. The specific heats and nearest-neighbor spin-spin
correlations are calculated thoughout the entire temperature and anisotropy
ranges in both ferromagnetic and antiferromagnetic regions, obtaining a global
description and quantitative results. We obtain, for all anisotropies, the
antiferromagnetic spin-liquid spin-wave velocity and the Isinglike
ferromagnetic excitation spectrum gap, exhibiting the spin-wave to spinon
crossover. A number of characteristics of purely quantum nature are found: The
in-plane interaction s_i^x s_j^x + s_i^y s_j^y induces an antiferromagnetic
correlation in the out-of-plane s_i^z component, at higher temperatures in the
antiferromagnetic XXZ chain, dominantly at low temperatures in the
ferromagnetic XXZ chain, and, in-between, at all temperatures in the XY chain.
We find that the converse effect also occurs in the antiferromagnetic XXZ
chain: an antiferromagnetic s_i^z s_j^z interaction induces a correlation in
the s_i^xy component. As another purely quantum effect, (i) in the
antiferromagnet, the value of the specific heat peak is insensitive to
anisotropy and the temperature of the specific heat peak decreases from the
isotropic (Heisenberg) with introduction of either type (Ising or XY)
anisotropy; (ii) in complete contrast, in the ferromagnet, the value and
temperature of the specific heat peak increase with either type of anisotropy.Comment: New results added to text and figures. 12 pages, 18 figures, 3
tables. Published versio
Histological and biochemical effects of cigarette smoke on lungs
In this study, rats were made to inhale cigarette smoke in a specifically prepared container for different periods. The lung tissue samples of the subjects were examined by light microscopy, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Malonaldehyde, one of the free oxygen radicals was determined in lungs and plasma. The catalase activity level of erythrocyte and arginase levels were determined. Three groups were formed. The rats in the Ist and IInd groups were made to inhale cigarette smoke for 30 and 60 minutes a day for a total period of 3 months. Control group, the rats in the IIIrd group (controls) were made to inhale clean air during the same periods. An increase in the number of macrophages was observed in the pulmonary tissue of the exposed groups. Especially in the group that inhaled the smoke for long periods, the number of macrophages and the inclusion bodies contained in them increased. These differences could easily be observed in TEM studies. In the light microscopy and SEM observations, it arouse attention that the alveolar macrophages occurred as sets and their activation increased. Depending on the length of the exposure to cigarette smoke, an increase in the number of macrophages was observed. Statistically significant increases were determined in the malonaldehyde levels of pulmonary tissue and plasma when compared to the control group. Besides significant increases were found in the catalase activity levels of erythrocytes in the experimental groups
Flows and Decompositions of Games: Harmonic and Potential Games
In this paper we introduce a novel flow representation for finite games in
strategic form. This representation allows us to develop a canonical direct sum
decomposition of an arbitrary game into three components, which we refer to as
the potential, harmonic and nonstrategic components. We analyze natural classes
of games that are induced by this decomposition, and in particular, focus on
games with no harmonic component and games with no potential component. We show
that the first class corresponds to the well-known potential games. We refer to
the second class of games as harmonic games, and study the structural and
equilibrium properties of this new class of games. Intuitively, the potential
component of a game captures interactions that can equivalently be represented
as a common interest game, while the harmonic part represents the conflicts
between the interests of the players. We make this intuition precise, by
studying the properties of these two classes, and show that indeed they have
quite distinct and remarkable characteristics. For instance, while finite
potential games always have pure Nash equilibria, harmonic games generically
never do. Moreover, we show that the nonstrategic component does not affect the
equilibria of a game, but plays a fundamental role in their efficiency
properties, thus decoupling the location of equilibria and their payoff-related
properties. Exploiting the properties of the decomposition framework, we obtain
explicit expressions for the projections of games onto the subspaces of
potential and harmonic games. This enables an extension of the properties of
potential and harmonic games to "nearby" games. We exemplify this point by
showing that the set of approximate equilibria of an arbitrary game can be
characterized through the equilibria of its projection onto the set of
potential games
Association Between Concussion Burden During Professional American-Style Football and Postcareer Hypertension
Previous work has demonstrated an association between American-style football (ASF) and the development of hypertension among collegiate athletes.1 In addition, hypertension prevalence has been shown to be higher among active professional ASF athletes compared with similarly aged members of the general population.2 Whereas causal factors including deliberate weight gain, repetitive isometric strength training, sleep apnea, and nonsteroidal anti-inflammatory drug use have been suggested, definitive mechanisms remain incompletely understood. Recent studies in general populations have shown associations between brain injury and subsequent hypertension.3 Given that ASF players are at particular risk for recurrent head injury, the relationship between concussion history and later life hypertension deserves focused exploration
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Temporal evolution of vasospasm and clinical outcome after intra-arterial vasodilator therapy in patients with aneurysmal subarachnoid hemorrhage
Intra-arterial (IA) vasodilator therapy is one of the recommended treatments to minimize the impact of aneurysmal subarachnoid hemorrhage-induced cerebral vasospasm refractory to standard management. However, its usefulness and efficacy is not well established. We evaluated the effect IA vasodilator therapy on middle cerebral artery blood flow and on discharge outcome. We reviewed records for 115 adults admitted to Neurointensive Care Unit to test whether there was a difference in clinical outcome (discharge mRS) in those who received IA infusions. In a subset of 19 patients (33 vessels) treated using IA therapy, we tested whether therapy was effective in reversing the trends in blood flow. All measures of MCA blood flow increased from day -2 to -1 before infusion (maximum Peak Systolic Velocity (PSV) 232.2±9.4 to 262.4±12.5 cm/s [p = 0.02]; average PSV 202.1±8.5 to 229.9±10.9 [p = 0.02]; highest Mean Flow Velocity (MFV) 154.3±8.3 to 172.9±10.5 [p = 0.10]; average MFV 125.5±6.3 to 147.8±9.5 cm/s, [p = 0.02]) but not post-infusion (maximum PSV 261.2±14.6 cm/s [p = .89]; average PSV 223.4±11.4 [p = 0.56]; highest MFV 182.9±12.4 cm/s [p = 0.38]; average MFV 153.0±10.2 cm/s [p = 0.54]). After IA therapy, flow velocities were consistently reduced (day X infusion interaction p<0.01 for all measures). However, discharge mRS was higher in IA infusion group, even after adjusting for sex, age, and admission grades. Thus, while IA vasodilator therapy was effective in reversing the vasospasm-mediated deterioration in blood flow, clinical outcomes in the treated group were worse than the untreated group. There is need for a prospective randomized controlled trial to avoid potential confounding effect of selection bias
Race differences in pain and pain-related risk factors among former professional American-style football players
The burden of pain is unequal across demographic groups, with broad and persisting race differences in pain-related outcomes in the United States. Members of racial and ethnic minorities frequently report more pervasive and severe pain compared with those in the majority, with at least some disparity attributable to differences in socioeconomic status. Whether race disparities in pain-related health outcomes exist among former professional football players is unknown. We examined the association of race with pain outcomes among 3995 former professional American-style football players who self-identified as either Black or White. Black players reported more intense pain and higher levels of pain interference relative to White players, even after controlling for age, football history, comorbidities, and psychosocial factors. Race moderated associations between several biopsychosocial factors and pain; higher body mass index was associated with more pain among White but not among Black players. Fatigue and psychosocial factors were more strongly related to pain among Black players relative to White players. Collectively, the substantial social and economic advantages of working as a professional athlete did not seem to erase race-related disparities in pain. We highlight an increased burden of pain among elite Black professional football players and identify race-specific patterns of association between pain and biopsychosocial pain risk factors. These findings illuminate potential future targets of interventions that may serve to reduce persistent disparities in the experience and impact of pain.</p
A Cognitive Model of an Epistemic Community: Mapping the Dynamics of Shallow Lake Ecosystems
We used fuzzy cognitive mapping (FCM) to develop a generic shallow lake
ecosystem model by augmenting the individual cognitive maps drawn by 8
scientists working in the area of shallow lake ecology. We calculated graph
theoretical indices of the individual cognitive maps and the collective
cognitive map produced by augmentation. The graph theoretical indices revealed
internal cycles showing non-linear dynamics in the shallow lake ecosystem. The
ecological processes were organized democratically without a top-down
hierarchical structure. The steady state condition of the generic model was a
characteristic turbid shallow lake ecosystem since there were no dynamic
environmental changes that could cause shifts between a turbid and a clearwater
state, and the generic model indicated that only a dynamic disturbance regime
could maintain the clearwater state. The model developed herein captured the
empirical behavior of shallow lakes, and contained the basic model of the
Alternative Stable States Theory. In addition, our model expanded the basic
model by quantifying the relative effects of connections and by extending it.
In our expanded model we ran 4 simulations: harvesting submerged plants,
nutrient reduction, fish removal without nutrient reduction, and
biomanipulation. Only biomanipulation, which included fish removal and nutrient
reduction, had the potential to shift the turbid state into clearwater state.
The structure and relationships in the generic model as well as the outcomes of
the management simulations were supported by actual field studies in shallow
lake ecosystems. Thus, fuzzy cognitive mapping methodology enabled us to
understand the complex structure of shallow lake ecosystems as a whole and
obtain a valid generic model based on tacit knowledge of experts in the field.Comment: 24 pages, 5 Figure
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income countries due to insufficient supply, high costs, and storage requirements. Global immunity could still benefit from new vaccines using widely available, safe adjuvants, such as alum and protein subunits, suited to low-cost production in existing manufacturing facilities. Here, a clinical-stage vaccine candidate comprising a SARS-CoV-2 receptor binding domain–hepatitis B surface antigen virus–like particle elicited protective immunity in cynomolgus macaques. Titers of neutralizing antibodies (>104) induced by this candidate were above the range of protection for other licensed vaccines in nonhuman primates. Including CpG 1018 did not significantly improve the immunological responses. Vaccinated animals challenged with SARS-CoV-2 showed reduced median viral loads in bronchoalveolar lavage (~3.4 log10) and nasal mucosa (~2.9 log10) versus sham controls. These data support the potential benefit of this design for a low-cost modular vaccine platform for SARS-CoV-2 and other variants of concern or betacoronaviruses
First light demonstration of the integrated superconducting spectrometer
Ultra-wideband 3D imaging spectrometry in the millimeter-submillimeter
(mm-submm) band is an essential tool for uncovering the dust-enshrouded portion
of the cosmic history of star formation and galaxy evolution. However, it is
challenging to scale up conventional coherent heterodyne receivers or
free-space diffraction techniques to sufficient bandwidths (1 octave) and
numbers of spatial pixels (>). Here we present the design and first
astronomical spectra of an intrinsically scalable, integrated superconducting
spectrometer, which covers 332-377 GHz with a spectral resolution of . It combines the multiplexing advantage of microwave kinetic
inductance detectors (MKIDs) with planar superconducting filters for dispersing
the signal in a single, small superconducting integrated circuit. We
demonstrate the two key applications for an instrument of this type: as an
efficient redshift machine, and as a fast multi-line spectral mapper of
extended areas. The line detection sensitivity is in excellent agreement with
the instrument design and laboratory performance, reaching the atmospheric
foreground photon noise limit on sky. The design can be scaled to bandwidths in
excess of an octave, spectral resolution up to a few thousand and frequencies
up to 1.1 THz. The miniature chip footprint of a few
allows for compact multi-pixel spectral imagers, which would enable
spectroscopic direct imaging and large volume spectroscopic surveys that are
several orders of magnitude faster than what is currently possible.Comment: Published in Nature Astronomy. SharedIt Link to the full published
paper: https://rdcu.be/bM2F
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