Anthropologie hypermédia

Pierre L. Jordan, maître de conférences Le séminaire, organisé sous forme d’enseignement groupé pour raisons techniques, a été divisé en trois parties : la première consacrée à l’histoire du film ethnographique, la deuxième aux applications multimédias et hypermédias en anthropologie, cependant, ces deux thèmes ont été abordés à partir d’applications hypermédias, certaines spécialement développées pour ce séminaire, enfin une troisième partie, plus technique a été dédiée aux instruments bibli..

Anthropologie hypermédia

Pierre L. Jordan, maître de conférences Le séminaire, organisé sous forme d’enseignement groupé pour des raisons techniques, a été divisé en deux parties : la première consacrée à l’histoire du film ethnographique, la seconde aux applications multimédias et hypermédias en anthropologie. Cependant, ces deux thèmes ont été abordés à partir d’applications hypermédias spécialement développées pour ce séminaire. Histoire du film ethnographique À partir du cédérom Cent ans de cinéma ethnographique ..

Anthropologie hypermédia

Pierre L. Jordan, maître de conférences Le séminaire, organisé sous forme d’enseignement groupé pour raisons techniques, a été divisé en trois parties : la première consacrée à l’histoire du film ethnographique, la deuxième aux applications multimédias et hypermédias en anthropologie, cependant, ces deux thèmes ont été abordés à partir d’applications hypermédias, certaines spécialement développées pour ce séminaire, enfin une troisième partie, plus technique a été dédiée aux instruments bibli..

Anthropologie hypermedia

Pierre L. Jordan, maître de conférences Comme l’année passée, le séminaire, organisé sous forme d’enseignement groupé pour raisons techniques, a été divisé en deux parties : la première consacrée à l’histoire du film ethnographique, la seconde aux applications multimédias et hypermédias en anthropologie, cependant, ces deux thèmes ont été abordés à partir d’applications hypermédias, certaines spécialement développées pour ce séminaire. Après avoir brossé l’historique des premiers hypermédias ..

Technical Proposal for FASER: ForwArd Search ExpeRiment at the LHC

FASER is a proposed small and inexpensive experiment designed to search for light, weakly-interacting particles during Run 3 of the LHC from 2021-23. Such particles may be produced in large numbers along the beam collision axis, travel for hundreds of meters without interacting, and then decay to standard model particles. To search for such events, FASER will be located 480 m downstream of the ATLAS IP in the unused service tunnel TI12 and be sensitive to particles that decay in a cylindrical volume with radius R=10 cm and length L=1.5 m. FASER will complement the LHC's existing physics program, extending its discovery potential to a host of new, light particles, with potentially far-reaching implications for particle physics and cosmology. This document describes the technical details of the FASER detector components: the magnets, the tracker, the scintillator system, and the calorimeter, as well as the trigger and readout system. The preparatory work that is needed to install and operate the detector, including civil engineering, transport, and integration with various services is also presented. The information presented includes preliminary cost estimates for the detector components and the infrastructure work, as well as a timeline for the design, construction, and installation of the experiment.Comment: 82 pages, 62 figures; submitted to the CERN LHCC on 7 November 201

Definition of the σW regulon of Bacillus subtilis in the absence of stress

Bacteria employ extracytoplasmic function (ECF) sigma factors for their responses to environmental stresses. Despite intensive research, the molecular dissection of ECF sigma factor regulons has remained a major challenge due to overlaps in the ECF sigma factor-regulated genes and the stimuli that activate the different ECF sigma factors. Here we have employed tiling arrays to single out the ECF σW regulon of the Gram-positive bacterium Bacillus subtilis from the overlapping ECF σX, σY, and σM regulons. For this purpose, we profiled the transcriptome of a B. subtilis sigW mutant under non-stress conditions to select candidate genes that are strictly σW-regulated. Under these conditions, σW exhibits a basal level of activity. Subsequently, we verified the σW-dependency of candidate genes by comparing their transcript profiles to transcriptome data obtained with the parental B. subtilis strain 168 grown under 104 different conditions, including relevant stress conditions, such as salt shock. In addition, we investigated the transcriptomes of rasP or prsW mutant strains that lack the proteases involved in the degradation of the σW anti-sigma factor RsiW and subsequent activation of the σW-regulon. Taken together, our studies identify 89 genes as being strictly σW-regulated, including several genes for non-coding RNAs. The effects of rasP or prsW mutations on the expression of σW-dependent genes were relatively mild, which implies that σW-dependent transcription under non-stress conditions is not strictly related to RasP and PrsW. Lastly, we show that the pleiotropic phenotype of rasP mutant cells, which have defects in competence development, protein secretion and membrane protein production, is not mirrored in the transcript profile of these cells. This implies that RasP is not only important for transcriptional regulation via σW, but that this membrane protease also exerts other important post-transcriptional regulatory functions

Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda

In this report we describe a newly discovered ebolavirus species which caused a large hemorrhagic fever outbreak in western Uganda. The virus is genetically distinct, differing by more than 30% at the genome level from all other known ebolavirus species. The unique nature of this virus created challenges for traditional filovirus molecular based diagnostic assays and genome sequencing approaches. Instead, we quickly determined over 70% of the virus genome using a recently developed random-primed pyrosequencing approach that allowed the rapid development of a molecular detection assay that was deployed in the disease outbreak response. This draft sequence allowed easy completion of the whole genome sequence using a traditional primer walking approach and prompt confirmation that this virus represented a new ebolavirus species. Current efforts to design effective diagnostics, antivirals and vaccines will need to take into account the distinct nature of this important new member of the filovirus family