Successful treatment of feline leishmaniosis using an association of allopurinol and N-methyl-glucamine antimoniate

This work describes the diagnosis and successful treatment of a 2-year-old domestic cat infected with Leishmania species and presenting fever, and ulcerative and nodular skin lesions after being treated for pyodermatitis for 1 year without clinical improvement. After anamnesis the cat was submitted to a complete clinical examination. Blood was collected for determination of haematological and biochemical parameters, detection of feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV), feline coronavirus (FCoV) and Leishmania amastigotes. Fine-needle aspiration puncture from the skin nodules was also performed. After definitive diagnosis the animal was treated and followed up over a 2 year period. The animal tested negative for FIV-specific antibodies, FeLV antigen and feline coronavirus RNA. Leishmania amastigotes in the skin nodules were confirmed by cytology and molecular diagnosis. Treatment was initiated with allopurinol, resulting in a slight clinical improvement. Thus, N-methyl-glucamine antimoniate was added and administered for 30 days, with complete closure of the ulcerative lesions in the hindlimbs requiring a surgical approach. Close monitoring of the patient in the following 24 months indicated that combined therapy was safe and clinical cure was achieved without further relapses or side effects.publishersversionpublishe

Determinants of the income velocity of money in Portugal: 1891–1998

This paper performs a long-run time series analysis of the behaviour of the income velocity of money in Portugal between 1891 and 1998 by assessing the importance of both macroeconomic and institutional factors and looking for particularities in the Portuguese case. We estimate two cointegration vectors for the income velocity of money, macroeconomic variables and institutional variables. It is apparent that one of these vectors reflects the relationship between income velocity and macroeconomic variables, while the other reflects the relationship between income velocity and institutional variables. Moreover, a regression analysis reveals that the usual U-shaped pattern is displayed with a relatively late inflection point located around 1970, which is consistent with the Spanish case. It is further noted that this is a feature of countries with a late economic and institutional development process.info:eu-repo/semantics/publishedVersio

Produtividade, estabilidade e adaptabilidade em progênies de Myracrodruon urundeuva F.F. & M.F. Allemão - Anacardiaceae.

A utilização de forma extrativista e inadequada dos recursos naturais vem restringindo a ocorrência da aroeira (Myracrodruon urundeuva F.F. & M.F. Allemão), constando, inclusive, na lista de espécies ameaçadas de extinção da FAO. Assim, a restrição da ocorrência, acarreta diminuição na base genética das populações de M. urundeuva, o que torna mais difícil encontrar genótipos com estabilidade e adaptabilidade para as diferentes condições de plantio. Dessa forma, o presente trabalho teve por objetivo estimar a variação genética e estudar a produtividade, estabilidade e adaptabilidade em progênies de uma população natural de M. urundeuva em diferentes sistemas de plantio. Para tanto, avaliou-se o DAP (diâmetro à altura do peito) em quatro testes de progênies de M. urundeuva: i) consorciada com Anandenanthera falcata e Guazuma ulmifolia (TP-AMA); ii) a pleno sol (TP-ASO); iii) ,em consórcio com culturas anuais (TP-SAF) e iv) consorciada com Corymbia citriodora (TP-EUCA), instalados em Selvíria, MS. O delineamento experimental utilizado foi o de blocos casualizados, com três repetições e número variável de plantas por parcela em cada um dos quatro sistemas de plantio. A partir da análise conjunta dos sistemas de plantio estudados, verificou-se que: i) houve variação entre os sistemas de plantio com destaque para o TP-SAF; ii) apenas no TP-EUCA foi possível detectar variação entre as progênies; iii) os efeitos da interação genótipo x ambiente não foram significativos. A média harmônica dos valores genotípicos (MHVG), o desempenho relativo dos valores genotípicos em relação à média de cada local (PRVG) e a média harmônica do desempenho relativo dos valores genotípicos (MHPRVG) para o caráter DAP evidenciaram, respectivamente, as progênies com maior estabilidade, adaptabilidade, e estabilidade e adaptabilidade simultaneamente nos diferentes sistemas de plantio. Assim, a utilização destes critérios de seleção proporcionou um refinamento a mais na seleção das melhores progênies de M. urundeuva nos diferentes sistemas de plantios estudados

Is there association between chronic kidney disease and dental caries? A case-controlled study

The purpose of this study was to assess the association between chronic kidney diseases (CKD) and dental caries. 107 patients with CKD and 107 with no systemic alteration were randomly included. DMFT (decayed, missing, and filled teeth), plaque index, colony-forming units (CFU) of Streptococcus mutans and salivary composition (IgA total, IgA anti- Streptococcus mutans, calcium and urea) were evaluated. McNemar and Wilcoxon tests were used to compare test and control groups. Spearman test was used to correlate time of hemodialysis and variables studied. Associations between variables were evaluated by logistic regression analysis. The number of filled teeth, the amount of IgA anti-Streptococcus mutans, salivary urea, education level, monthly income and the amount of CFU of Streptococcus mutans were statistically different between groups. There was a positive correlation between the duration of hemodialysis (Hd) and the amount of IgA anti-Streptococcus mutans, urea in saliva, and the number of CFU of Streptococcus mutans. In the adjusted model, a higher incidence of CFU mutans streptococci, elevated salivary urea, smaller number of filled teeth, lower DMFT, and less calcium salivary were associated with CKD. Programs to prevent and treat oral problems and regular follow-up at the beginning of dialysis are necessary to increase patients? awareness of their condition