1,094 research outputs found

    Identity and identification of Trogulus banaticus (Opiliones: Trogulidae) : a neglected species in the Northern Balkans

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    Trogulus banaticus Avram, 1971 is characterised and recorded as new for Slovenia. This species was previously mistaken for T. coriziformis C. L. Koch, 1839 and T. graecus Dahl, 1903 which were later rejected from the Slovenian fauna. T. banaticus is compared with the similar, and partly sympatric, T. tingiformis C. L. Koch, 1847 with which it has often been confused. A table of distinguishing characters for both species is provided, and the ecology of T. banaticus and its general distribution are discussed

    Of Ecosystems and Economies: Re-connecting Economics with Reality

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    This discussion paper looks at the connections between economies and ecosystems, or more generally biophysical reality. The term "economies" is used, rather than "the economy", because of the prevalent false claim that there is only one type of economic system that is possible. We outline how the ecological crises is linked to the dominant drive for economic growth and the tendency to equate growth with progress and development; common even amongst those apparently critical of the need for continued growth in the materially rich countries. The unreality of mainstream economics is epitomised by the accolades given to those justifying mild reformist policy in response to human induced climate change in order to continue the pursuit of economic growth. We emphasise the structural aspects of economies as emergent from and dependent upon the structure and functioning of both society and ecology (energy and material flows). Finally, that the structure of the global economy must change to avoid social ecological collapse, poses the questions of how that can be achieved and what sort of economics is necessary? We explain the need for: (i) a structural change that addresses the currently dysfunctional relationships between economic, social and ecological systems, and (ii) an economics that is interdisciplinary and realist about its social and natural science relations.Series: SRE - Discussion Paper

    US hospital performance: A dynamic network analysis

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    Workshop 2013 on Dynamic and Network DEA (January 29-30, 2013)Healthcare is a critical and costly industry. In the U.S. a significant component of healthcare costs are expenses generated in hospitals. This paper reports the results of analyzing 607 U.S. hospitals between 2006-2009 using a dynamic network slack-based Data Envelopment Analysis (DEA) Model. We find accounting for the dynamic and network structure of the hospital lowers efficiency estimates. Further, hospitals are more efficient at providing hospital services compared to hotel services, but the efficiency of hospitals is not correlated with their size. Regarding the dynamic network slack-based DEA Model, we find slack-based approaches combine technical and allocative aspects of inefficiency and thus tend to have significantly lower efficiency levels than just radial technical efficiency measures. Further when applying an envelopment method like DEA, there are some benefits to averaging multiple years of data to remove variation and avoid estimating a frontier based on observations that might have significant noise in their measurement.This workshop is supported by JSPS KAKENHI Grant Number 22310092 under the title “Theory and Applications of Dynamic DEA with Network Structure.

    Subtypes of Attentional Bias within Social Anxiety Disorder: Evaluating Changes following Cognitive Behavioral Therapy

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    Prominent theories of social anxiety disorder (SAD) describe the role of attentional bias in the disorder\u27s etiology and maintenance; some models implicate bias toward social threats (e.g., Rapee & Heimberg, 1997) and others implicate bias to avoid them (e.g., Clark & Wells, 1995). The present investigation examined: 1) whether a clinical sample of individuals with SAD comprises two distinct groups based on attention bias for social threat (vigilant, avoidant), and 2) group-specific changes in attention bias following cognitive behavioral therapy (CBT) for SAD. Consistent with predictions, results yielded evidence of two pre-treatment groups (vigilant and avoidant). After eight weeks of treatment, the direction of change in attention bias differed between groups, such that the vigilant group became less vigilant, and the avoidant group became less avoidant, with the avoidant group showing a significant change in attention bias from pre- to post-treatment. These findings provide preliminary support for the hypothesis that SAD comprises subgroups with both threat vigilant and threat avoidant attentional styles and change in different directions following treatment. Implications for how individuals who exhibit one attentional bias or the other may differentially respond to treatment are discussed

    A dynamic-network slacks-based measure with an application to Japanese Prefectures

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    Workshop 2015 -Advances in DEA Theory and Applications (December 1-2, 2015)This paper develops a dynamic-network DEA (data envelopment analysis) model where total output is jointly produced from two sectors: a human capital sector and a physical capital sector. While human capital is treated as an exogenous input, physical capital production is an intermediate output of one period that becomes an input to a subsequent period. The method is applied using pooled data on 47 Japanese prefectures during the period 2007-2009.The workshop is supported by JSPS (Japan Society for the Promotion of Science), Grant-in-Aid for Scientific Research (B), #25282090, titled “Studies in Theory and Applications of DEA for Forecasting Purpose.本研究はJSPS科研費 基盤研究(B) 25282090の助成を受けたものです

    Eating self-efficacy as predictor of long-term weight loss and obesity-specific quality of life after sleeve gastrectomy: A prospective cohort study

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    Under embargo until: 15.12.2019Background: A person's confidence to control eating, eating self-efficacy (ESE), has been identified as a target for long-term weight management in nonsurgical weight loss interventions, but has to a limited extent been studied after bariatric surgery. Objective: We investigated the association between ESE, weight loss, and obesity-specific quality of life (QOL) after sleeve gastrectomy (SG). Setting: A single-center longitudinal study. Methods: Data from adult patients were collected before SG, and at mean 16 months (±standard deviation 4 mo) and 55 (±4) months postoperatively. ESE was measured by the Weight Efficacy Lifestyle Questionnaire Short-Form. Multiple regression analyses were performed with excess body mass index loss (%EBMIL) and obesity-specific QOL as dependent variables. Age, sex, and other preoperative values were covariates in all models. Results: Of 114 preoperative patients, 91 (80%) and 84 (74%) were available for follow-up 16 and 55 months after SG, respectively. Mean %EBMIL from baseline to 16 and 55 months was 76% (95% confidence interval: 71.9, 79.6) and 67% (95% confidence interval: 61.9, 72.2), respectively. Preoperative ESE scores improved significantly at both 16 and 55 months (P = .002) but did not predict postoperative %EBMIL or QOL at 55 months (β = −.08, P = .485). Greater change in ESE from 0 to 16 months predicted higher %EBMIL (β = .34, P = .013) at 55 months, and improvements in ESE from 0 to 55 months were significantly associated with higher %EBMIL (β = .46, P = .001) and obesity-specific QOL (β = .50, P < .001) 55 months after SG. Conclusion: Significant improvements in ESE were seen at 16 months, and remained high at 55 months after SG in this cohort. Patients who improved their ESE the most also experienced the highest weight loss and obesity-specific QOL 5 years postoperatively. Future research should address whether enhancement of ESE corresponds to sustained improvements in eating behavior after bariatric surgery.acceptedVersio

    Screening of Feral and Wood Pigeons for Viruses Harbouring a Conserved Mobile Viral Element: Characterization of Novel Astroviruses and Picornaviruses

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    A highly conserved RNA-motif of yet unknown function, called stem-loop-2-like motif (s2m), has been identified in the 3′ end of the genomes of viruses belonging to different RNA virus families which infect a broad range of mammal and bird species, including Astroviridae, Picornaviridae, Coronaviridae and Caliciviridae. Since s2m is such an extremely conserved motif, it is an ideal target for screening for viruses harbouring it. In this study, we have detected and characterized novel viruses harbouring this motif in pigeons by using a s2m-specific amplification. 84% and 67% of the samples from feral pigeons and wood pigeons, respectively, were found to contain a virus harbouring s2m. Four novel viruses were identified and characterized. Two of the new viruses belong to the genus Avastrovirus in the Astroviridae family. We propose two novel species to be included in this genus, Feral pigeon astrovirus and Wood pigeon astrovirus. Two other novel viruses, Pigeon picornavirus A and Pigeon picornavirus B, belong to the Picornaviridae family, presumably to the genus Sapelovirus. Both of the novel picornaviruses harboured two adjacent s2m, called (s2m)2, suggesting a possible increased functional effect of s2m when present in two copies

    Does engagement with exposure yield better outcomes?: Components of presence as a predictor of treatment response for virtual reality exposure therapy for social phobia

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    Virtual reality exposure (VRE) has been shown to be effective for treating a variety of anxiety disorders, including social phobia. Presence, or the level of connection an individual feels with the virtual environment, is widely discussed as a critical construct both for the experience of anxiety within a virtual environment and for a successful response to VRE. Two published studies show that whereas generalized presence relates to fear ratings during VRE, it does not relate to treatment response. However, presence has been conceptualized as multidimensional, with three primary factors (spatial presence, involvement, and realness). These factors can be linked to other research on the facilitation of fear during exposure, inhibitors of treatment response (e.g., distraction), and more recent theoretical discussions of the mechanisms of exposure therapy, such as Bouton’s (2004) description of expectancy violation. As such, one or more of these components of presence may be more strongly associated with the experience of fear during VRE and treatment response than the overarching construct. The current study (N=41) evaluated relations between three theorized components of presence, fear ratings during VRE, and treatment response for VRE for social phobia. Results suggest that total presence and realness subscale scores were related to in-session peak fear ratings. However, only scores on the involvement subscale significantly predicted treatment response. Implications of these findings are discussed

    Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cells

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    <p>Abstract</p> <p>Background</p> <p>The association between <it>Helicobacter pylori </it>infection and upper gastrointestinal disease is well established. However, only a small fraction of <it>H. pylori </it>carriers develop disease, and there are great geographical differences in disease penetrance. The explanation to this enigma lies in the interaction between the bacterium and the host. <it>H. pylori </it>Outer Membrane Phospholipase A (OMPLA) has been suggested to play a role in the virulence of this bacterium. The aim of this study was to profile the most significant cellular pathways and biological processes affected in gastric epithelial cells during 24 h of <it>H. pylori </it>exposure, and to study the inflammatory response to OMPLA<sup>+ </sup>and OMPLA<sup>- </sup><it>H. pylori </it>variants.</p> <p>Results</p> <p>Interleukin-8 was the most significantly up-regulated gene and appears to play a paramount role in the epithelial cell response to <it>H. pylori </it>infection and in the pathological processes leading to gastric disease. MAPK and NF-kappaB cellular pathways were powerfully activated, but did not seem to explain the impressive <it>IL-8 </it>response. There was marked up-regulation of <it>TP53BP2</it>, whose corresponding protein ASPP2 may interact with <it>H. pylori </it>CagA and cause marked p53 suppression of apoptosis. Other regulators of apoptosis also showed abberant regulation. We also identified up-regulation of several oncogenes and down-regulation of tumor suppressor genes as early as during the first 24 h of infection. <it>H. pylori </it>OMPLA phase variation did not seem to influence the inflammatory epithelial cell gene response in this experiment.</p> <p>Conclusion</p> <p>In whole genome analysis of the epithelial response to <it>H. pylori </it>exposure, <it>IL-8 </it>demonstrated the most marked up-regulation, and was involved in many of the most important cellular response processes to the infection. There was dysregulation of apoptosis, tumor suppressor genes and oncogenes as early as in the first 24 h of <it>H. pylori </it>infection, which may represent early signs of gastric tumorigenesis. OMPLA<sup>+/-</sup>did not affect the acute inflammatory response to <it>H. pylori</it>.</p

    Schizotypy and Nicotine, Alcohol, and Cannabis Use in a Non-Psychiatric Sample

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    Schizotypy is a multidimensional personality construct that is characterized by perceptual abnormalities, social withdrawal, mild suspiciousness, and odd thinking patterns. This study examined the relationship between four dimensions of self-reported schizotypy and substance use involving nicotine, alcohol, and cannabis, in undergraduate students. Results showed that higher levels of disorganized schizotypy, or odd thinking and behavior, were associated with greater indices of use of all three substances. Furthermore, higher cognitive-perceptual schizotypy was selectively associated with cannabis use. Results confirm findings of recent research that has discovered associations among schizotypy and substance use, highlighting links between behavioral traits and use of nicotine, alcohol, and cannabis. This study is one of the first to examine a wide range of schizotypy domains, and to show selective effects of the disorganized domain of schizotypy
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