2,213 research outputs found

    Entre psychiatrie et allégorie : le paradoxe du délire dans Berlin Alexanderplatz

    Get PDF
    Actes du colloque de l'Université Stendhal de Grenoble, 2008.International audienc

    Measure of genuine multipartite entanglement with computable lower bounds

    Full text link
    We introduce an intuitive measure of genuine multipartite entanglement which is based on the well-known concurrence. We show how lower bounds on this measure can be derived that also meet important characteristics of an entanglement measure. These lower bounds are experimentally implementable in a feasible way enabling quantification of multipartite entanglement in a broad variety of cases.Comment: 5 pages, 2 figure

    On Overcoming Barriers to Application of Neuroinflammation Research

    Get PDF
    Throughout history, new ideas in medicine or science have met initial resistance by entrenched medical or scientific communities. Barriers to medical innovation fall into six main categories as listed here in order of historical chronology: (1) Theological, (2) Academic, (3) Scientific, (4) Financial, (5) Governmental, and (6) Commercial. Researchers in the field of neuroinflammation often encounter such obstacles that may include denialism. Despite these barriers, recognition of the therapeutic potential of targeting neuroinflammation for treatment of stroke, traumatic brain injury, Alzheimer’s disease, spinal pain, and a variety of additional brain disorders has accelerated in the past 10 years. Consequently, a paradigm shift in scientific thinking regarding neuroinflammation as a therapeutic target is now underway

    Mass Spectrometry Imaging Disclosed Spatial Distribution of Defense-Related Metabolites in Triticum spp

    Get PDF
    Fusarium Head Blight is the most common fungal disease that strongly affects Triticum spp., reducing crop yield and leading to the accumulation of toxic metabolites. Several studies have investigated the plant metabolic response to counteract mycotoxins accumulation. However, information on the precise location where the defense mechanism is taking place is scarce. Therefore, this study aimed to investigate the specific tissue distribution of defense metabolites in two Triticum species and use this information to postulate on the metabolites’ functional role, unlocking the “location-to-function” paradigm. To address this challenge, transversal cross-sections were obtained from the middle of the grains. They were analyzed using an atmospheric-pressure (AP) SMALDI MSI source (AP-SMALDI5 AF, TransMIT GmbH, Giessen, Germany) coupled to a Q Exactive HF (Thermo Fisher Scientific GmbH, Bremen, Germany) orbital trapping mass spectrometer. Our result revealed the capability of (AP)-SMALDI MSI instrumentation to finely investigate the spatial distribution of wheat defense metabolites, such as hydroxycinnamic acid amides, oxylipins, linoleic and α-linoleic acids, galactolipids, and glycerolipids

    NUMERICAL STUDY OF THE GEOMETRIC INFLUENCE OF A FIN IN A CYLINDRICAL HEAT EXCHANGER FOR MELTING OF PCM

    Get PDF
    The thermal heat storage it’s an effective way to suit the energy availability with the demand schedule. It can be stored in the means of sensible or latent heat, the latter applying a material denominated Phase Change Material (PCM), which is provided as organic compounds, hydrated salts, paraffins, among others. The latent heat storage systems offer several advantages, like the practically isothermal process of loading and unloading and the high energy density. However, the low thermal conductivity makes the cycle prolonged on these systems, restricting its applicability. Applying computational fluid dynamics, the behavior of the PCM melting process was studied in cylindrical cavities with horizontal and vertical fins, aiming the optimization of the fin geometry. In this way the fin area was kept constant, varying its aspect ratio. The numerical model was validated with results from the literature and it’s composed of the continuity, momentum and energy equations increased by the phase change model. Qualitative and quantitative results are presented, referring to mesh independence, contours of velocity, net fraction and temperature at different moments of the process. The results of the study indicate that the position of the fin in the heat exchanger influences the melting process, although the vertical fins have a faster total melting process, horizontal fins can reach larger partial liquid fractions in less time in the heat exchanger. Such as the position of the fin, the increase of its length propitiates the reduction of the melting time, evidencing the optimal aspect ratio

    Effect of extended surfaces on lauric acid melting process in annular cavities

    Get PDF
    The objective of the present work is to parametrically analyze the effect of extended surfaces’ proportion and positioning on the lauric acid melting process, in an annular cavity. In total 46 geometric configurations were studied, varying between 5 area ratios, 5 proportions, and 2 positions of the extended surface. Numerical simulations performed with the finite volume method were used to conduct the study. The numerical model, composed of the continuity, momentum conservation, and energy conservation equations, plus the enthalpy-porosity phase change model, was validated with experimental data from the literature. The Grid Convergence Index (GCI) was used to evaluate the computational mesh, resulting in an average index of 0.0026%. The results are presented in terms of liquid fraction vs Fourier, and Nusselt number vs. Fourier. Besides, velocity vectors, and streamlines, liquid fraction, and temperature fields, were presented, comparing different instants and geometric arrangements. For the analysis of the results, the melting time was considered as a performance indicator. The results revealed that: while there is solid PCM in the cavity's upper section, the melting rate in systems with horizontal extensions is 15% higher than systems with vertical extensions; when the extended surface thinness is increased, the overall melting time is reduced by more than 10% in vertical arrangements and less than 1.5% in horizontal arrangements; the total melting time is nearly 45% faster in systems with vertical extensions than in systems with horizontal extensions
    • …
    corecore