3D Data Processing Toward Maintenance and Conservation. The Integrated Digital Documentation of Casa de Vidro

During the last decade, 3D integrated surveys and BIM modelling procedures have greatly improved the overall knowledge on some Brazilian Modernist buildings. In this framework, the Casa de Vidro 3D survey carried out by DIAPReM centre at Ferrara University, beside the important outputs, analysis and researches achieved from the point cloud database processing, was also useful to test several awareness increasing activities in cooperation with local stakeholders. The first digital documentation test of the Casa de Vidro allowed verifying the feasibility of a full survey on the building towards the restoration and possible placement of new architectures into the garden as an archive-museum of the Lina Bo and P.M. Bardi Foundation. Later, full 3D integrated survey and diagnostic analysis were carried out to achieve the total digital documentation of the house sponsored by the Keeping it Modern initiative of Getty Foundation (Los Angeles). Following its characteristics, the survey had to take into consideration the different architectural features, up to the relationship of architecture and nature. These 3D documentation activities and the point cloud processing allowed several analysis in a multidisciplinary framework

Prevalence and clinical correlates of sarcopenia in institutionalized older people: Cross-sectional study of a nursing home population

Background & aims. Sarcopenia is a common condition among institutionalized older people which leads to increased risk of adverse outcomes such as disability and death. We investigated the prevalence and clinical correlates of sarcopenia in older institutionalized adults in Italy, while also evaluating the interchangeability and adequacy of two definitions of sarcopenia (EWGSOP and FNIH) for this geriatric setting. Methods. Cross-sectional analysis of 97 participants enrolled in a nursing home facility in Italy. Since 97% of the study subjects resulted either unable to walk or “slow walkers”, we assessed sarcopenia presence ignoring the walking speed criterion: sarcopenia was assessed as low appendicular skeletal mass index plus low grip strength (EWGSOP criteria) and as weakness plus low lean mass (FNIH criteria). Skeletal muscle mass was estimated using bioimpendance analysis. Results. In this population of 97 institutionalized older people (age 83.2 ± 9.4 years, women 73.2%), according to both EWGSOP and FNIH criteria 13 participants (13.4%) were identified as affected by sarcopenia; however, only 5 subjects were identified as sarcopenic according to both definitions simultaneously. The prevalence of sarcopenia was directly correlated with male sex and comorbidity level, while being inversely correlated with Body Mass Index. Conclusions. According to EWGSOP and FNIH criteria, prevalence of sarcopenia is significant among institutionalized older people, and it’s strongly related to male sex, BMI and comorbidity level. EWGSOP and FNIH criteria identified as sarcopenic different individuals and therefore cannot be used interchangeably. Assessment of walking speed might be unfeasible in institutionalized older subjects

INVESTIGATIONS ON THE DESIGN PROCESS OF ELADIO DIESTE: 3D PARAMETRIC MODELLING OF MODERN LATIN AMERICAN ARCHITECTURAL HERITAGE

Abstract. The Uruguayan Engineer Eladio Dieste underwent a quest for thinness in the field of structural design which rendered his reinforced masonry thin-shell structures at a conspicuous position in Modern Latin American Architectural Heritage, so much so as to have Dieste's work in Latin America and Europe included in an indicative list for UNESCO's cultural heritage sites as of 2010. Nonetheless, the design process that led Dieste to such innovative structural typologies is yet to be fully academically explored. Thus, the objective of this paper is to examine the state-of-art regarding the intricate design process of Eladio Dieste's gaussian vaults and shed some light on the existing gaps within this process by means of the 3D parametric modelling and digital fabrication of selected case studies. The adoption methodological procedures such as 3D parametrical modelling and digital fabrication allows for the establishment of important relationships between the design process and the resulting geometry of Eladio Dieste's designs, as well as furthering registry of Dieste's legacy for conservation purposes.</p

3D SURVEY FOR TECHNOLOGY TRANSFER: LARGO DA MEMORIA IN SÃO PAULO, BRAZIL

With the broadening of the concept of Cultural Heritage - which now, in addition to great monuments, also includes urban cores, landscapes and intangible manifestations - the possibilities for heritage conservation actions have also expanded. Nowadays, in a globalised world immersed in technologies that are evolving with astonishing rapidity, precisely technological innovation can be an important ally for the enhancement of historic public spaces.On the occasion of the bicentenary of the placement of the existing obelisk in the “Largo da Memória” public space (in the centre of São Paulo), a three-dimensional survey pilot project was carried out in cooperation with local municipality. One of the objectives of this project was to develop an example of “good practices” for the conservation of urban space and a possible benchmark for the use of digital data by local technicians avoiding expansive software and hardware solutions. Thus, the three-dimensional survey of the area helped to evaluate the effectiveness of the optimisation of the integrated procedure, taking into consideration the importance of the public space of the Largo, at the intersection of Xavier de Toledo and Quirino de Andrade streets. Technology transfer actions played an important role within the whole process, enabling further evaluations for the conservation of the place by local authorities.</p

Effects of a Robot-Assisted Arm Training Plus Hand Functional Electrical Stimulation on Recovery After Stroke: A Randomized Clinical Trial

Objective: To compare the effects of unilateral, proximal arm robot-assisted therapy combined with hand functional electrical stimulation with intensive conventional therapy for restoring arm function in survivors of subacute stroke. Design: This was a single-blinded, randomized controlled trial. Setting: Inpatient rehabilitation university hospital. Participants: Patients (N=40) diagnosed as having ischemic stroke (time since stroke &lt;8wk) and upper limb impairment were enrolled. Interventions: Participants randomized to the experimental group received 30 sessions (5 sessions/wk) of robot-assisted arm therapy and hand functional electrical stimulation (RAT+FES). Participants randomized to the control group received a time-matched intensive conventional therapy. Main Outcome Measures: The primary outcome was arm motor recovery measured with the Fugl-Meyer Motor Assessment. Secondary outcomes included motor function, arm spasticity, and activities of daily living. Measurements were performed at baseline, after 3 weeks, at the end of treatment, and at 6-month follow-up. Presence of motor evoked potentials (MEPs) was also measured at baseline. Results: Both groups significantly improved all outcome measures except for spasticity without differences between groups. Patients with moderate impairment and presence of MEPs who underwent early rehabilitation (&lt;30d post stroke) demonstrated the greatest clinical improvements. Conclusions: RAT+FES was no more effective than intensive conventional arm training. However, at the same level of arm impairment and corticospinal tract integrity, it induced a higher level of arm recovery

Forced expiratory volume in one second: A novel predictor of work disability in subjects with suspected obstructive sleep apnea

Whether the association of work disability with obstructive sleep apnea (OSA) is mainly due to the disease, i.e. the number and frequency of apneas-hypoapneas, or to coexisting factors independent from the disease, is not well-established. In this study, we aim to evaluate work ability in a group of subjects undergoing OSA workup and to identify the major contributors of impaired work ability. In a cross-sectional study, we enrolled 146 consecutive subjects who have been working for the last five years and referred to the sleep disorders outpatients’ clinic of the University-Hospital of Ferrara, Italy, with suspected OSA. After completing an interview in which the Work Ability Index (WAI) and the Epworth Sleepiness Scale (ESS) questionnaires were administered to assess work ability and excessive daytime sleepiness, respectively, subjects underwent overnight polysomnography for OSA diagnosing and spirometry. Of the 146 subjects, 140 (96%) completed the tests and questionnaires and, of these, 66 exhibited work disability (WAI &lt; 37). OSA was diagnosed (apnea-hypopnea index 5) in 45 (68%) of the 66 subjects. After controlling for confounders, a lower level of forced expiratory volume at 1 second (FEV1), [odds ratio 0.97 (95% CI 0.95–1.00)], older age [1.09 (95% CI 1.03–1.15)], excessive daytime sleepiness [3.16 (95% CI 1.20–8.34)] and a worse quality of life [0.96 (95% CI 0.94–1.00)], but not OSA [1.04 (95% CI 0.41–2.62)], were associated with work disability. Patients with a higher number of diseases, in which OSA was not included, and a lower quality of life had an increased probability of absenteeism in the previous 12 months. In subjects with suspected OSA, FEV1 can be an important predictor of work disability

THE ARCHITECTURAL GEOMETRY OF THE CHURCH OF CRISTO OBRERO Y NUESTRA SEÑORA DE LOURDES

The object of study of this paper is the Church of Cristo Obrero y Nuestra Señora de Lourdes, in the city of Atlántida, Uruguay, designed and built by Uruguayan engineer Eladio Dieste between 1956 and 1960, and proclaimed as a UNESCO World Heritage Site in 2021. Furthermore, the object of study is the outset of Eladio Dieste’s experimentations with reinforced brickwork, which resulted in innovative thin-shell structural typologies. Hence, the objective of this article is to verify the geometrical relationships within the continuous gaussian vaults of the Cristo Obrero’ roof and the ruled surfaces of its lateral walls. The proposed methodological procedures for this research were the in situ visitation of the object of study, followed by the consultation of original construction drawings, as well as the exploratory parametric modeling and polynomial regression of the architectural geometry of the Church of Cristo Obrero. Amongst the expected contributions for this research reside the dissemination of Latin-American modern architectural heritage sites within European academic journals, digital design technologies within Latin-American research centres, as well as the fostering of the comprehension of the design and construction process of the Uruguayan engineer Eladio Dieste

Technical results, clinical efficacy and predictors of outcome of intercostal arteries embolization for hemothorax: A two-institutions’ experience

Background: To evaluate the clinical efficacy and identify the predictors of outcome of intercostal arterial embolization for hemothorax caused by intercostal artery (ICA) injuries. Methods: A retrospective multi-institutional study was conducted. Outcomes were analyzed in 30 consecutive patients presenting with hemothorax caused by active ICA hemorrhage undergoing transcatheter arterial embolization (TAE). Clinical and procedural parameters were compared between outcomes groups. Results: Overall technical success rate was 87% (n=26). Among the 4 failed cases, 2 underwent repeated TAE and 2 underwent additional surgery. Overall 30-day mortality rate was 23%. Low haemoglobin levels and haematocrit, hepatic comorbidities and more than one artery undergoing embolization increased technical failure rate significantly. Survival was poorer in patients with massive bleeding. Conclusions: ICA embolization was found to be a safe and effective method in treating hemothorax caused by active ICA haemorrhage. Careful pre-embolization evaluation may be required for patient with low haemoglobin levels and haematocrit, hepatic comorbidities and active haemorrhage from more than one artery

Early Light Chains Removal and Albumin Levels with a Double Filter-Based Extracorporeal Treatment for Acute Myeloma Kidney

Renal impairment in Multiple Myeloma (MM) represents one of the most important factors that influences patient survival. In fact, before the introduction of modern chemotherapy, less than 25% of patients with acute kidney injury (AKI) and MM who required dialysis recovered sufficient renal function to become independent from dialysis, with a median overall survival of less than 1 year. There are many other factors involved in determining patient survival. In this study we aimed to investigate the role of double filter-based extracorporeal treatment for removal of serum free light chains (sFLC) in acute myeloma kidney (AKI for MM) and to evaluate patient overall survival. All patients received Bortezomib-based chemotherapy and extracorporeal treatment for sFLC removal. For each session 2 dialyzers of the same kind were used. The dialytic dose was not related to the degree of renal function but to the removal of sFLC. The factors that have been found to be significantly associated with lower mortality were reduction of sFLC at day 12 and day 30, &gt;50% reduction of sFLC at day 30, number of sessions and independence from dialysis. Among baseline characteristics, albumin level was statistically associated with the patients’ outcome. Our analysis highlights the importance of the early treatment for removal of sFLC in AKI for MM. These results indicate that the early removal of sFLC can improve patient’s outcome

The impact of cognitive function deficits and their recovery on functional outcome in subjects affected by ischemic subacute stroke: results from the Italian multicenter longitudinal study CogniReMo

Background: The recovery of independence in activities of daily living is a fundamental goal of rehabilitation programs in subjects affected by subacute stroke. Rehabilitation is focused both on motor and cognitive aspects, and some evidence has reported cognitive deficits as prognostic factors of motor recovery. However, rehabilitation is a dynamic process during which executive functions and motor functions should be improved. Aim: The aim of the study is to evaluate the relationships between impairments in cognitive functions and recovery of functional independence in stroke patients during the subacute phase. Design: Multicenter observational study. Setting: Intensive rehabilitation units. Population: A sample of 319 stroke patients in subacute phase (70.6±11.6 years, 40.4% females), consecutively admitted from November 2019 to July 2021 at sixteen rehabilitation centers were enrolled in this observational, prospective and multicentric study with longitudinal assessments. Methods: Cognitive and functional assessments were performed at hospital admission and discharge, including Oxford Cognitive Screen, modified Barthel Index, Functional Independent Measure, Fugl-Meyer assessment scale and National Institutes of Health Stroke Scale. Results: A regression analysis identified five predictors (out of about 200 tested variables) of functional recovery related to four aspects assessed at admission: functional status (P&lt;0.001), lower limb functioning (P=0.002), attention (P=0.011), and executive functions (P=0.017). Furthermore, patients who recovered deficits in executive functions had the same recovery of those without deficits, whereas those who maintained deficits had a smaller recovery (P=0.019). Conclusions: The relationship between cognitive and motor deficits is increasingly highlighted and the recovery of executive functions deficits seems to contribute to motor recovery. Clinical rehabilitation impact: Our results suggest that the recovery of executive functions may promote the recovery of the functional outcome of the patient with subacute stroke. Future treatment protocols may benefit from paying more attention to the recovery of executive functions