5,916 research outputs found

    Infrared behavior and Gribov ambiguity in SU(2) lattice gauge theory

    Full text link
    For SU(2) lattice gauge theory we study numerically the infrared behavior of the Landau gauge ghost and gluon propagators with the special accent on the Gribov copy dependence. Applying a very efficient gauge fixing procedure and generating up to 80 gauge copies we find that the Gribov copy effect for both propagators is essential in the infrared. In particular, our best copy dressing function of the ghost propagator approaches a plateau in the infrared, while for the random first copy it still grows. Our best copy zero-momentum gluon propagator shows a tendency to decrease with growing lattice size which excludes singular solutions. Our results look compatible with the so-called decoupling solution with a non-singular gluon propagator. However, we do not yet consider the Gribov copy problem to be finally resolved.Comment: 9 pages, 9 figure

    Dysfunction of the visual sensory thalamus in developmental dyslexia

    Get PDF
    Developmental dyslexia (DD) is a reading disorder with a prevalence of 5-10%. Neuroscientific research has typically focused on explaining DD symptoms based on pathophysiological changes in the cerebral cortex. However, DD might also be associated with alterations in sensory thalami – central subcortical stations of sensory pathways. A post-mortem study on the visual sensory thalamus (lateral geniculate nucleus, LGN) showed histopathological changes in the magnocellular (M-LGN), but not in the parvocellular (P-LGN), subdivisions. M-LGN and P-LGN have different functional properties and belong to two different visual systems. Whether M-LGN alterations also exist in DD in-vivo is unclear. Also, the potential relevance of M-LGN alterations to DD symptoms is unknown. This lack of knowledge is partly due to considerable technical challenges in investigating LGN subdivisions non-invasively in humans. Here, we employed recent advances in high-field 7 Tesla functional magnetic resonance imaging (fMRI) to map the M- and P-LGN in-vivo in DD adults (n=26) and matched controls (n=28). We show that (i) M-LGN responses differ between DD and control participants, (ii) these differences are more pronounced in male than in female DD participants, and (iii) M-LGN alterations predict a core symptom of DD in male DD participants only, i.e., rapid naming ability. Our results provide a first functional interpretation of M-LGN changes in DD and support DD theories that propose a direct relevance of sensory thalamus alterations for DD symptoms. In addition, the sex-specific behavioral relevance of M-LGN alterations within DD calls for taking sex differences into account when planning brain-based therapeutic interventions

    The Fossil Phase in the Life of a Galaxy Group

    Full text link
    We investigate the origin and evolution of fossil groups in a concordance LCDM cosmological simulation. We consider haloes with masses between (1-5)\times10^{13} \hMsun and study the physical mechanisms that lead to the formation of the large gap in magnitude between the brightest and the second most bright group member, which is typical for these fossil systems. Fossil groups are found to have high dark matter concentrations, which we can relate to their early formation time. The large magnitude-gaps arise after the groups have build up half of their final mass, due to merging of massive group members. We show that the existence of fossil systems is primarily driven by the relatively early infall of massive satellites, and that we do not find a strong environmental dependence for these systems. In addition, we find tentative evidence for fossil group satellites falling in on orbits with typically lower angular momentum, which might lead to a more efficient merger onto the host. We find a population of groups at higher redshifts that go through a ``fossil phase'': a stage where they show a large magnitude-gap, which is terminated by renewed infall from their environment.Comment: 9 pages and 8 figures, submitted to MNRA

    NetCoMi: network construction and comparison for microbiome data in R

    Get PDF
    MOTIVATION Estimating microbial association networks from high-throughput sequencing data is a common exploratory data analysis approach aiming at understanding the complex interplay of microbial communities in their natural habitat. Statistical network estimation workflows comprise several analysis steps, including methods for zero handling, data normalization and computing microbial associations. Since microbial interactions are likely to change between conditions, e.g. between healthy individuals and patients, identifying network differences between groups is often an integral secondary analysis step. Thus far, however, no unifying computational tool is available that facilitates the whole analysis workflow of constructing, analysing and comparing microbial association networks from high-throughput sequencing data. RESULTS Here, we introduce NetCoMi (Network Construction and comparison for Microbiome data), an R package that integrates existing methods for each analysis step in a single reproducible computational workflow. The package offers functionality for constructing and analysing single microbial association networks as well as quantifying network differences. This enables insights into whether single taxa, groups of taxa or the overall network structure change between groups. NetCoMi also contains functionality for constructing differential networks, thus allowing to assess whether single pairs of taxa are differentially associated between two groups. Furthermore, NetCoMi facilitates the construction and analysis of dissimilarity networks of microbiome samples, enabling a high-level graphical summary of the heterogeneity of an entire microbiome sample collection. We illustrate NetCoMi's wide applicability using data sets from the GABRIELA study to compare microbial associations in settled dust from children's rooms between samples from two study centers (Ulm and Munich). AVAILABILITY R scripts used for producing the examples shown in this manuscript are provided as supplementary data. The NetCoMi package, together with a tutorial, is available at https://github.com/stefpeschel/NetCoMi. CONTACT Tel:+49 89 3187 43258; [email protected]. SUPPLEMENTARY INFORMATION Supplementary data are available at Briefings in Bioinformatics online

    Memory Effect and Triplet Pairing Generation in the Superconducting Exchange Biased Co/CoOx/Cu41Ni59/Nb/Cu41Ni59 Layered Heterostructure

    Full text link
    We fabricated a nanolayered hybrid superconductor-ferromagnet spin-valve structure, the resistive state of which depends on the preceding magnetic field polarity. The effect is based on a strong exchange bias (about -2 kOe) on a diluted ferromagnetic copper-nickel alloy and generation of a long range odd in frequency triplet pairing component. The difference of high and low resistance states at zero magnetic field is 90% of the normal state resistance for a transport current of 250 {\mu}A and still around 42% for 10 {\mu}A. Both logic states of the structure do not require biasing fields or currents in the idle mode.Comment: 9 pages, 4 figures, Accepted to Applied Physics Letter

    Interaction-induced delocalization of two particles in a random potential: Scaling properties

    Full text link
    The localization length ξ2\xi_2 for coherent propagation of two interacting particles in a random potential is studied using a novel and efficient numerical method. We find that the enhancement of ξ2\xi_2 over the one-particle localization length ξ1\xi_1 satisfies the scaling relation ξ2/ξ1=f(u/Δξ)\xi_2/\xi_1=f(u/\Delta_\xi), where uu is the interaction strength and Δξ\Delta_{\xi} the level spacing of a wire of length ξ1\xi_1. The scaling function ff is linear over the investigated parameter range. This implies that ξ2\xi_2 increases faster with uu than previously predicted. We also study a novel mapping of the problem to a banded-random-matrix model.Comment: 5 pages and two figures in a uuencoded, compressed tar file; uses revtex and psfig.sty (included); substantial revision of a previous version of the paper including newly discovered scaling behavio

    Predicting enhanced absorption of light gases in polyethylene using simplified PC-SAFT and SAFT-VR

    Get PDF
    International audienceAbsorption of light gases in polyethylene (PE) is studied using two versions of the Statistical Associating Fluid Theory (SAFT): SAFT for chain molecules with attractive potentials of variable range (VR) and simplified perturbed-chain (PC) SAFT. Emphasis is placed on the light gases typically present during ethylene polymerisation in the gas-phase reactor (GPR) process. The two approaches are validated using experimental binary-mixture data for gas absorbed in PE, and predictions are made for mixtures of more components. For most cases studied both SAFT versions perform equally well. For the case of ternary mixtures of two gases with PE, it is predicted that the less-volatile of the two gases acts to enhance the absorption of the more-volatile gas, while the more-volatile gas inhibits the absorption of the less-volatile gas. This general behaviour is also predicted in mixtures containing more gases, such as typical reactor mixtures. The magnitude of the effect may vary considerably, depending on the relative proximity of the gas-mixture saturation pressure to the reactor pressure; for example it is predicted that the absorption of ethylene may be approximately doubled if diluent gases, propane or nitrogen, are partially or completely replaced by less-volatile butane or pentane for a reactor pressure similar to 2 MPa. In the case of a co-polymerisation reaction, it is predicted that increases in absorption of both co-monomers may be obtained in roughly equal proportion. Our findings cast light on the so-called co-monomer effect, in which substantial increases in the rate of ethylene polymerisation are observed in the presence of hexene co-monomer, while suggesting that the effect is more general and not restricted to co-monomer. For example, similar rate increases may be expected in the presence of, e.g., pentane instead of hexene, but without the change in the branch structure of the produced polymer that is inevitable when the amount of co-monomer is increased

    Reentrant Superconductivity and Superconducting Critical Temperature Oscillations in F/S/F trilayers of Cu41Ni59/Nb/Cu41Ni59 Grown on Cobalt Oxide

    Full text link
    Ferromagnet/Superconductor/Ferromagnet (F/S/F) trilayers constitute the core of a superconducting spin valve. The switching effect of the spin valve is based on interference phenomena occurring due to the proximity effect at the S/F interfaces. A remarkable effect is only expected if the core structure exhibits strong critical temperature oscillations, or most favorable, reentrant superconductivity, when the thickness of the ferromagnetic layer is increased. The core structure has to be grown on an antiferromagnetic oxide layer (or such layer to be placed on top) to pin by exchange bias the magnetization-orientation of one of the ferromagnetic layers. In the present paper we demonstrate that this is possible, keeping the superconducting behavior of the core structure undisturbed.Comment: 22 pages, 12 figures, 1 tabl

    Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe

    Get PDF
    Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential zoonotic transmission are scarce. Methods: 80 Zimbabwean C. difficile isolates from different sources (chicken [n = 30], soil [n = 21] and humans [n = 29]) were investigated using ribotyping, toxin gene detection, resistance testing, multiple-locus variable-number tandem repeat analysis (MLVA), and whole genome sequencing (WGS). Results: Among chicken isolates, the most common RTs were RT103 (6/30), RT025 (5/30) and RT070 (4/30). Within soil samples, RT025 and RT056 were most common (3/21 each). In contrast, the non-toxigenic RT084 was most frequently found in human isolates (4/29). Toxin genes were detected in only 19/29 human isolates. Susceptibility testing showed no resistance against metronidazole and vancomycin, and resistance against macrolides and rifampicin was scarce (3/80 and 2/80, respectively); however, 26/80 isolates showed moxifloxacin resistance. MLVA and WGS of strains with identical RTs stemming from different sources revealed clustering of RT025 and RT084 isolates from human und non-human samples. Conclusion: No "hypervirulent” strains were found. The detected clusters between human, chicken and soil isolates indicate ongoing transmission between humans and environmental sources and might point towards a zoonotic potential
    corecore