Online vaccine-related information-seeking in mothers and HPV vaccine uptake in their daughters

Background: There is widespread concern about online vaccine misinformation. The aim of this study was to investigate the association between seeking vaccine-related information on the Internet and HPV vaccination uptake. Methods: Data were obtained from the 2015, 2016, 2017 and 2018 Vaccinoscopie® studies, a pluriannual web-based survey conducted on a nationally representative quota sample of mothers to monitor the dynamics of vaccine coverage, perception and attitudes towards vaccination in France. Mothers of girls aged 14-15 years were asked to state all vaccinations reported on the vaccinal pages of their child's healthcare records. We computed univariate and multivariate logistic regression models, with the outcome variable “HPV vaccination” defined as equal to 1 if the daughter received at least one dose of HPV vaccine, and equal to 0 otherwise; and the dependant variable “Internet use” defined as equal to 1 if the mother responded “Internet” (alone or combined with other sources) to the question “When in doubt about a vaccine, what source(s) of information do you turn to to decide whether or not to have your child vaccinated?”, and equal to 0 otherwise. Results: Over the 4 years, a total of 2038 mothers answered the self-administered online questionnaire. Overall, 96.1% declared their need to search for information, 23.9% of whom used the Internet as a source. Maternal Internet use was associated with lower HPV vaccination uptake in their daughters (Odds Ratio (OR)=0.49, 95%CI: 0.38-0.64). The association remained after adjusting for several potential confounders, including area of residence, household socio-professional category and income, maternal level of education, physician recommendation and use of other sources of information (adjusted OR = 0.68, 95%CI: 0.48-0.96). Conclusions: Specific information campaigns are required to empower parents to better use online information and guide them to reputable sources when they seek information on vaccination. Key messages: The findings of this study suggest that the use of online sources on information is negatively associated with HPV vaccination. Action is warranted to direct parents to use more correct online sources of information on vaccination

Emotional expressiveness of 5–6 month-old infants born very premature versus full-term at initial exposure to weaning foods

Facial expressions of 5–6 month-old infants born preterm and at term were compared while tasting for the first time solid foods (two fruit and two vegetable purées) given by the mother. Videotapes of facial reactions to these foods were objectively coded during the first six successive spoons of each test food using Baby FACS and subjectively rated by naïve judges. Infant temperament was also assessed by the parents using the Infant Behaviour Questionnaire. Contrary to our expectations, infants born preterm expressed fewer negative emotions than infants born full-term. Naïve judges rated infants born preterm as displaying more liking than their full-term counterparts when tasting the novel foods. The analysis of facial expressions during the six spoonfuls of four successive meals (at 1-week intervals) suggested a familiarization effect with the frequency of negative expressions decreasing after tasting the second spoon, regardless of infant age, type of food and order of presentation. Finally, positive and negative dimensions of temperament reported by the parents were related with objective and subjective coding of affective reactions toward foods in infants born preterm or full-term. Our research indicates that premature infants are more accepting of novel foods than term infants and this could be used for supporting the development of healthy eating patterns in premature infants. Further research is needed to clarify whether reduced negativity by infants born prematurely to the exposure to novel solid foods reflects a reduction of an adaptive avoidant behaviour during the introduction of novel foods

Impact de l’extension de la vaccination obligatoire sur les couvertures vaccinales du nourrisson : des premiers résultats prometteurs

International audienceOBJECTIVE: In France infant vaccines protecting against 11 diseases have changed from a recommended to a mandatory status for all children born on or after January 1, 2018. Using the Vaccinoscopie survey, we measured the impact of this new vaccination policy on vaccine coverage rates (VCRs) and on mothers' perception of vaccination.METHODS: Online survey with 1000 mothers of 0- to 11-month-old infants.RESULTS: VCRs for at least one dose at the age of 6 months strongly progressed for diseases that previously did not meet Public Health objectives (+8 points for Hepatitis B and +31 points for meningococcal C vaccines). Mothers were more favorable to mandatory vaccination and better informed in 2018 than in 2017.CONCLUSIONS: These first results showed a positive impact of the extension of mandatory vaccination on mothers' opinion regarding vaccination and on infant VCRs.Objectifs: En France, pour les enfants nés depuis le 1er janvier 2018, les vaccins du nourrisson protégeant contre 11 maladies, auparavant recommandés, sont devenus obligatoires. L’enquête Vaccinoscopie permet de mesurer l’impact de cette nouvelle politique vaccinale sur les couvertures vaccinales (CV) et l’opinion des mères sur la vaccination.Méthodes: Étude réalisée sur Internet par questionnaire auto-administré auprès de 1000 mères de nourrissons âgés de 0–11 mois.Résultats: Les CV pour au moins une dose à l’âge de 6 mois ont fortement progressé pour les valences qui n’atteignaient pas les objectifs de santé publique (+8 points pour l’hépatite B et +31 points pour le méningocoque C). Les mères étaient plus favorables à la vaccination obligatoire et mieux informées en 2018 qu’en 2017.Conclusion: Ces premiers résultats montrent un impact positif de l’extension de la vaccination obligatoire sur les CV du nourrisson et sur l’opinion des mères quant à la vaccination