Soft sediment deformation in Confusion Gulch

Confusion Gulch is located in Sanpete County, Utah, near the town of Ephraim, on the east face of the Gunnison Plateau. The rocks exposed in this area range in age from Jurassic to Eocene, and are represented by the Twist Gulch, Indianola, North Horn, and Flagstaff formations. The rocks of these formations represent lake, flood plain, and marine deposits. The structures present in Confusion Gulch suggest that the rocks making up the North Horn formation were deformed before they were completely lithified. Soft sediment is indicated by the formation of tight folds in sandstone that is now brittle, cracked pebbles in a conglomerate whose matrix is undisturbed, and split pebbles that have been bonded by sand matrix. Soft sediment deformation is responsible for the formation of the tight "S" fold on the front of the Gunnison Plateau, and for its overturned fold in the center section of Confusion Gulch

The effects of isometric work on heart rate, blood pressure, and net oxygen cost

Isometric exercise effects on heart rate, blood pressure, and net oxygen cos

Conflict in northern Arnhem Land

The thesis is a study of disputes among the Gidjingali and neigh­bouring peoples of northern Arnhem Land. Chapter 1 outlines the demographic, ecological, and historical background, and I follow this with a brief account of the conditions under which I carried out fieldwork. Chapters 2, 3, and 4 present the main features of Gidjingali social organization: land-owning units and residential associations are dealt with in Chapter 2, organization for ritual purposes in Chapter 3, and the system of kinship and marriage in Chapter 4» Chapters 5 and. 6 give a classification and analysis of conflict - in the former those relating to the acquisition of wives; in the latter those over property, adultery, insult, and injury. Chapter 7 is an analysis of social control among the Gidjingali considered in the light of statements that have been made about Aboriginal government and political organization.Includes article Local organization among the Australian aborigines by the author from Oceania, v.32, no.

Diffusion theory and knowledge dissemination, utilization and integration

Many accomplishments of public health have been distributed unevenly among populations. This article reviews the concepts of applying evidence-based practice in public health in the face of the varied cultures and circumstances of practice in these varied populations. Key components of EBPH include: making decisions based on the best available scientific evidence, using data and information systems systematically, applying program planning frameworks, engaging the community and practitioners in decision making, conducting sound evaluation, and disseminating what is learned. The usual application of these principles has overemphasized the scientific evidence as the starting point, whereas this review suggests engaging the community and practitioners as an equally important starting point to assess their needs, assets and circumstances, which can be facilitated with program planning frameworks and use of local assessment and surveillance data

Insights on the Role of Diabetes and Geographic Variation in Patients with Criticial Limb Ischaemia

AbstractBackgroundPatients with critical limb ischaemia (CLI) unsuitable for revascularisation have a high rate of amputation and mortality (30% and 25% at 1 year, respectively). Localised gene therapy using plasmid DNA encoding acidic fibroblast growth factor (NV1FGF, riferminogene pecaplasmid) has showed an increased amputation-free survival in a phase II trial. This article provides the rationale, design and baseline characteristics of CLI patients enrolled in the pivotal phase III trial (EFC6145/TAMARIS).MethodsAn international, double-blind, placebo-controlled, randomised study composed of 525 CLI patients recruited from 170 sites worldwide who were unsuitable for revascularisation and had non-healing skin lesions was carried out to evaluate the potential benefit of repeated intramuscular administration of NV1FGF. Randomisation was stratified by country and by diabetic status.ResultsThe mean age of the study cohort was 70 ± 10 years, and included 70% males and 53% diabetic patients. Fifty-four percent of the patients had previous lower-extremity revascularisation and 22% had previous minor amputation of the index leg. In 94% of the patients, the index leg had distal occlusive disease affecting arteries below the knee. Statins were prescribed for 54% of the patients, and anti-platelet drugs for 80%. Variation in region of origin resulted in only minor demographic imbalance. Similarly, while diabetic status was associated with a frequent history of coronary artery disease, it had little impact on limb haemodynamics and vascular lesions.ConclusionsClinical characteristics and vascular anatomy of CLI patients with ischaemic skin lesions who were unsuitable for revascularisation therapy show little variations by region of origin and diabetic status. The findings from this large CLI cohort will contribute to our understanding of this disease process.This study is registered with ClinicalTrials.gov, number NCT00566657

Association of Regional Variation in Primary Care Physicians’ Colorectal Cancer Screening Recommendations with Individual Use of Colorectal Cancer Screening

Introduction: Studies show that the recommendations of a primary care physician for colorectal cancer screening may be one important influence on an individual's use of screening. However, another possible influence, the effect of regional differences in physicians' beliefs and recommendations on screening use, has not been assessed. Methods: We linked data from the National Health Interview Survey on the use of colorectal cancer screening by respondents aged 50 years or older, by hospital-referral region, with data from the Survey of Colorectal Cancer Screening Practices on the colorectal cancer screening recommendations of primary care physicians, by region. Our principal independent variables were the proportion of physicians in a region who recommended screening at age 50 and continuing screening at the recommended frequency. Results: On average, 53.3% of physicians in a region correctly recommended initiating colorectal cancer screening, and 64.8% advised screening at the recommended frequency. Of adults who lived in regions where less than 30% of physicians correctly recommended initiating screening, 47.3% had been screened, in contrast to 54.8% in areas where 70% or more of physicians made correct recommendations. Seventy-one percent of respondents living in regions where less than 30% of physicians advised screening at the recommended frequency were current on screening, in contrast to 79.9% of respondents living in regions where 70% or more of physicians made this recommendation. These differences were statistically significant after adjustment for individual characteristics. Conclusion: Strategies to improve colorectal cancer screening recommendations of primary care physicians may improve the use of screening for millions of Americans

Homogeneity and Heterogeneity as Situational Properties: Producing – and Moving Beyond? – Race in Post-Genomic Science

In this article, we explore current thinking and practices around the logics of difference in gene–environment interaction research in the post-genomic era. We find that scientists conducting gene–environment interaction research continue to invoke well-worn notions of racial difference and diversity, but use them strategically to try to examine other kinds of etiologically significant differences among populations. Scientists do this by seeing populations not as inherently homogeneous or heterogeneous, but rather by actively working to produce homogeneity along some dimensions and heterogeneity along others in their study populations. Thus we argue that homogeneity and heterogeneity are situational properties – properties that scientists seek to achieve in their study populations, the available data, and other aspects of the research situation they are confronting, and then leverage to advance post-genomic science. Pointing to the situatedness of homogeneity and heterogeneity in gene–environment interaction research underscores the work that these properties do and the contingencies that shape decisions about research procedures. Through a focus on the situational production of homogeneity and heterogeneity more broadly, we find that gene–environment interaction research attempts to shift the logic of difference from solely racial terms as explanatory ends unto themselves, to racial and other dimensions of difference that may be important clues to the causes of complex diseases