Biosecurity Economics: Conflicting results in evaluation criteria

Determining the optimal policy response to a species invasion is a multidimensional problem. The choice between eradication or containment has social, environmental, political and economic dimensions. Often, economic evaluation is used as a basis to underpin policy decisions. However, under certain conditions economic evaluation criteria may provide conflicting results. Deterministic factors, such as rate of spread, degree of damage and the time until detection, are derived for identifying when caution must be taken with the results of economic evaluation criteria. The conditions under which conflicting results may be obtained between NPV and BCR are identified and linked to policy implications.Biosecurity economics, eradication, containment, invasive species,

RNA Vaccine: novel approach for cancer treatment

Cancer is still an unsolved puzzle and a major cause of mortality and morbidity in the world. Today, about one in every thousand people is dying due to cancer. No effective agent has yet been found which can cure cancer in its metastatic stage. However, attempts in the shape of chemotherapy, immunotherapy and vaccines are made worldwide to find a remedy through a proper regimen. In continuation, tumor specific mRNA has been introduced as part of vaccines in recent days. It is mostly used in transfection with Dendritic Cells (DCs) for better effectiveness and safety. The DCs are selected for transfection because they are highly potent Antigen Presenting Cells (APCs) with the ability to take up & process tumor antigen in peripheral blood & tissues and can also migrate to the draining lymph nodes to present antigen to naïve T lymphocytes & induce the immune response.
Although initially the RNA vaccination was administered alone, due to its unstable and easily degradable nature, it was found to be quite less effective, which led it to be used in combination with some stability enhancers’ viz. RNA packaging in liposomes. They not only increased its stability, but even worked as active immune stimulators as well. RNA could remain stable. Although it showed significant promise in cancer treatment, immune suppression was noticed after vaccination. To enhance the effectiveness it is now being used in combination with few drugs viz. SUNITINIB which can reduce the suppressive effect of suppressor cells. It might be a good choice for combined therapy with RNA vaccine.
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A Landau fluid model for warm collisionless plasmas

A Landau fluid model for a collisionless electron-proton magnetized plasma, that accurately reproduces the dispersion relation and the Landau damping rate of all the magnetohydrodynamic waves, is presented. It is obtained by an accurate closure of the hydrodynamic hierarchy at the level of the fourth order moments, based on linear kinetic theory. It retains non-gyrotropic corrections to the pressure and heat flux tensors up to the second order in the ratio between the considered frequencies and the ion cyclotron frequency.Comment: to appear in Phys. Plasma

Design of DC Microgrid Based on Photovoltaic Power Supply System

This paper describes the possibilities of the application of DC Microgrids to solve the energy problem in the country. DC Microgrids open a gateway for integration of solar energy which is efficient and cleaner way of renewable energy generation, which can be integrated into the power distribution network. DC microgrid is an intelligent mix of smart grid and renewable source with increase in the efficiency of energy. Therefore, very little energy is wasted during distribution and transmission. It has several other advantages, which include - reduction in transmission losses, improvement in power quality & reliability, reduction in emissions and even it is cost effective. The circuit for solar power availability sensing and switching to battery supply is done on hardware. Design of DC microgrid from the solar energy is done in MATLAB/SIMULINK. The most important characteristic is that it provides a possibility for electrification of remote villages which are far from the reach of the conventional grid

Potential Use of DC Microgrid for Solar and Wind Power Integration in Rural Areas in India: a Review

This paper describes the possibilities of the application of DC microgrids to solve the rural areas, energy problem in the country (India). DC Microgrids open a gateway for integration of solar and wind energies which together are an efficient and cleaner way of renewable energy generation, which can be integrated into the power distribution network. They have several other advantages, which include - reduction in transmission losses, improvement in power quality & reliability, reduction in emissions and even they are cost effective. The most important characteristic is that it provides a possibility for electrification of remote villages, which are far from the reach of the conventional grid. This paper presents a detailed discussion on the possibility of application of DC microgrids for rural areas in India

A new approximation scheme in quantum mechanics

An approximation method which combines the perturbation theory with the variational calculation is constructed for quantum mechanical problems. Using the anharmonic oscillator and the He atom as examples, we show that the present method provides an efficient scheme in estimating both the ground and the excited states. We also discuss the limitations of the present method.Comment: 14pages, to be published in Eur. J. Phy

Nanodot to Nanowire: A strain-driven shape transition in self-organized endotaxial CoSi2 on Si (100)

We report a phenomenon of strain-driven shape transition in the growth of nanoscale self-organized endotaxial CoSi2 islands on Si (100) substrates. Small square shaped islands as small as 15\times15 nm2 have been observed. Islands grow in the square shape following the four fold symmetry of the Si (100) substrate, up to a critical size of 67 \times 67 nm2. A shape transition takes place at this critical size. Larger islands adopt a rectangular shape with ever increasing length and the width decreasing to an asymptotic value of ~25 nm. This produces long wires of nearly constant width.We have observed nanowire islands with aspect ratios as large as ~ 20:1. The long nanowire heterostructures grow partly above (~ 3 nm) the surface, but mostly into (~17 nm) the Si substrate. These self-organized nanostructures behave as nanoscale Schottky diodes. They may be useful in Si-nanofabrication and find potential application in constructing nano devices.Comment: 9 pages, 7 figure

What can the SNO Neutral Current Rate teach us about the Solar Neutrino Anomaly

We investigate how the anticipated neutral current rate from $SNO$ will sharpen our understanding of the solar neutrino anomaly. Quantitative analyses are performed with representative values of this rate in the expected range of $0.8 - 1.2$. This would provide a $5 - 10 \sigma$ signal for $\nu_e$ transition into a state containing an active neutrino component. Assuming this state to be purely active one can estimate both the $^8B$ neutrino flux and the $\nu_e$ survival probability to a much higher precision than currently possible. Finally the measured value of the $NC$ rate will have profound implications for the mass and mixing parameters of the solar neutrino oscillation solution.Comment: Brief discussion on the first NC result from SNO added; final version to be published in the MPL