737 research outputs found

    Connie Myers v. Albertsons, Inc. : Brief of Appellee

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    Appeal of the Judgment of Michael Glasmann Based upon a Jury Verdict Second Judicial District Court Weber County, State of Uta

    Demonstration of synchronised scanning Lidar measurements of 2D velocity fields in a boundary-layer wind tunnel

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    This paper combines the currently relevant research methodologies of scaled wind turbine model experiments in wind tunnels with remote-sensing short-range WindScanner Lidar measurement technology. The wind tunnel of the Politecnico di Milano was equipped with three wind turbine models and two short-range WindScanner Lidars to demonstrate the benefits of synchronised scanning Lidars in such experimental surroundings for the first time. The dual- Lidar system can provide fully synchronised trajectory scans with sampling time scales ranging from seconds to minutes. First, staring mode measurements were compared to hot wire probe measurements commonly used in wind tunnels. This yielded goodness of fit coefficients of 0.969 and 0.902 for the 1 Hz averaged u- and v-components of the wind speed, respectively, validating the 2D measurement capability of the Lidar scanners. Subsequently, the measurement of wake profiles on a line as well as wake area scans were executed to illustrate the applicability of Lidar scanning to measuring small scale wind flow effects. The downsides of Lidar with respect to the hot wire probes are the larger measurement probe volume and the loss of some measurements due to moving blades. In contrast, the benefits are the high flexibility in conducting both point measurements and area scanning, and the fact that remote sensing techniques do not disturb the flow while measuring. The research campaign revealed a high potential for using short-range WindScanner Lidar for accurately measuring small scale flow structures in a wind tunnel

    Rank-(n – 1) convexity and quasiconvexity for divergence free fields

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    The CAST experiment at CERN (European Organization of Nuclear Research) searches for axions from the sun. The axion is a pseudoscalar particle that was motivated by theory thirty years ago, with the intention to solve the strong CP problem. Together with the neutralino, the axion is one of the most promising dark matter candidates. The CAST experiment has been taking data during the last two years, setting an upper limit on the coupling of axions to photons more restrictive than from any other solar axion search in the mass range below 0.1 eV. In 2005 CAST will enter a new experimental phase extending the sensitivity of the experiment to higher axion masses. The CAST experiment strongly profits from technology developed for high energy physics and for X-ray astronomy: A superconducting prototype LHC magnet is used to convert potential axions to detectable X-rays in the 1-10 keV range via the inverse Primakoff effect. The most sensitive detector system of CAST is a spin-off from space technology, a Wolter I type X-ray optics in combination with a prototype pn-CCD developed for ESA's XMM-Newton mission. As in other rare event searches, background suppression and a thorough shielding concept is essential to improve the sensitivity of the experiment to the best possible. In this context CAST offers the opportunity to study the background of pn-CCDs and its long term behavior in a terrestrial environment with possible implications for future space applications. We will present a systematic study of the detector background of the pn-CCD of CAST based on the data acquired since 2002 including preliminary results of our background simulations.Comment: 11 pages, 8 figures, to appear in Proc. SPIE 5898, UV, X-Ray, and Gamma-Ray Space Instrumentation for Astronomy XI

    Kan welzijn melkvee in ligboxenstallen nog beter?

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    Het Praktijkonderzoek Veehouderij heeft geonventariseerd welke verbeteringen mogelijk zijn met betrekking tot dierwelzijn

    Detecting modules in dense weighted networks with the Potts method

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    We address the problem of multiresolution module detection in dense weighted networks, where the modular structure is encoded in the weights rather than topology. We discuss a weighted version of the q-state Potts method, which was originally introduced by Reichardt and Bornholdt. This weighted method can be directly applied to dense networks. We discuss the dependence of the resolution of the method on its tuning parameter and network properties, using sparse and dense weighted networks with built-in modules as example cases. Finally, we apply the method to data on stock price correlations, and show that the resulting modules correspond well to known structural properties of this correlation network.Comment: 14 pages, 6 figures. v2: 1 figure added, 1 reference added, minor changes. v3: 3 references added, minor change

    Stable long-term outcomes after cochlear implantation in subjects with TMPRSS3 associated hearing loss:a retrospective multicentre study

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    Background: The spiral ganglion hypothesis suggests that pathogenic variants in genes preferentially expressed in the spiral ganglion nerves (SGN), may lead to poor cochlear implant (CI) performance. It was long thought that TMPRSS3 was particularly expressed in the SGNs. However, this is not in line with recent reviews evaluating CI performance in subjects with TMPRSS3-associated sensorineural hearing loss (SNHL) reporting overall beneficial outcomes. These outcomes are, however, based on variable follow-up times of, in general, 1 year or less. Therefore, we aimed to 1. evaluate long-term outcomes after CI implantation of speech recognition in quiet in subjects with TMPRSS3-associated SNHL, and 2. test the spiral ganglion hypothesis using the TMPRSS3-group. Methods: This retrospective, multicentre study evaluated long-term CI performance in a Dutch population with TMPRSS3-associated SNHL. The phoneme scores at 70 dB with CI in the TMPRSS3-group were compared to a control group of fully genotyped cochlear implant users with post-lingual SNHL without genes affecting the SGN, or severe anatomical inner ear malformations. CI-recipients with a phoneme score ≤ 70% at least 1-year post-implantation were considered poor performers and were evaluated in more detail. Results: The TMPRSS3 group consisted of 29 subjects (N = 33 ears), and the control group of 62 subjects (N = 67 ears). For the TMPRSS3-group, we found an average phoneme score of 89% after 5 years, which remained stable up to 10 years post-implantation. At both 5 and 10-year follow-up, no difference was found in speech recognition in quiet between both groups (p = 0.830 and p = 0.987, respectively). Despite these overall adequate CI outcomes, six CI recipients had a phoneme score of ≤ 70% and were considered poor performers. The latter was observed in subjects with residual hearing post-implantation or older age at implantation. Conclusion: Subjects with TMPRSS3-associated SNHL have adequate and stable long-term outcomes after cochlear implantation, equal to the performance of genotyped patient with affected genes not expressed in the SGN. These findings are not in line with the spiral ganglion hypothesis. However, more recent studies showed that TMPRSS3 is mainly expressed in the hair cells with only limited SGN expression. Therefore, we cannot confirm nor refute the spiral ganglion hypothesis.</p

    Stable long-term outcomes after cochlear implantation in subjects with TMPRSS3 associated hearing loss:a retrospective multicentre study

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    Background: The spiral ganglion hypothesis suggests that pathogenic variants in genes preferentially expressed in the spiral ganglion nerves (SGN), may lead to poor cochlear implant (CI) performance. It was long thought that TMPRSS3 was particularly expressed in the SGNs. However, this is not in line with recent reviews evaluating CI performance in subjects with TMPRSS3-associated sensorineural hearing loss (SNHL) reporting overall beneficial outcomes. These outcomes are, however, based on variable follow-up times of, in general, 1 year or less. Therefore, we aimed to 1. evaluate long-term outcomes after CI implantation of speech recognition in quiet in subjects with TMPRSS3-associated SNHL, and 2. test the spiral ganglion hypothesis using the TMPRSS3-group. Methods: This retrospective, multicentre study evaluated long-term CI performance in a Dutch population with TMPRSS3-associated SNHL. The phoneme scores at 70 dB with CI in the TMPRSS3-group were compared to a control group of fully genotyped cochlear implant users with post-lingual SNHL without genes affecting the SGN, or severe anatomical inner ear malformations. CI-recipients with a phoneme score ≤ 70% at least 1-year post-implantation were considered poor performers and were evaluated in more detail. Results: The TMPRSS3 group consisted of 29 subjects (N = 33 ears), and the control group of 62 subjects (N = 67 ears). For the TMPRSS3-group, we found an average phoneme score of 89% after 5 years, which remained stable up to 10 years post-implantation. At both 5 and 10-year follow-up, no difference was found in speech recognition in quiet between both groups (p = 0.830 and p = 0.987, respectively). Despite these overall adequate CI outcomes, six CI recipients had a phoneme score of ≤ 70% and were considered poor performers. The latter was observed in subjects with residual hearing post-implantation or older age at implantation. Conclusion: Subjects with TMPRSS3-associated SNHL have adequate and stable long-term outcomes after cochlear implantation, equal to the performance of genotyped patient with affected genes not expressed in the SGN. These findings are not in line with the spiral ganglion hypothesis. However, more recent studies showed that TMPRSS3 is mainly expressed in the hair cells with only limited SGN expression. Therefore, we cannot confirm nor refute the spiral ganglion hypothesis.</p

    Ethical conference economies? Reimagining the costs of convening academic communities when moving online

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    Online conferences are widely thought to reduce many of the costs of convening academic communities. From lower carbon emissions, lower fees, less difficulty in attending (particularly for marginalised researchers), and greater accessibility, virtual events promise to address many of the issues that in-person events take for granted. In this article, we draw on a community economies framing from geographers J.K. Gibson-Graham to argue for centring the work of convening within efforts to explore reparative possibilities within the academy. Reflecting on the changing costs arising from moving an originally in-person conference series online, we argue for embracing the opportunities offered. We explore how organising teams might enact alternative values through allocating the material, financial and labour resources traditionally spent for these events differently. We look particularly at how our carbon and financial costs changed, and how, by retaining a fee, we were able to allocate our budgets in ways which redistributed the surplus to participants in need (rather than bolster conference centre profits). We then explore what these changing costs meant in terms of our attendance levels across career stages and geographical locations. Looking at whether our experiment resulted in increased support for online events, we examine the continued ambivalence felt for the virtual. Finally, while we largely explore the benefits of online options, our last section urges caution over assumptions that this move will result in a more sustainable academia, particularly given the intensifications surrounding high quality streaming video, and suggest that we treat current trends as ongoing experiments, rather than solutions
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