170 research outputs found

    Quality of life in automatic implantable cardioverter defibrillator recipients

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    Morfología de huevos de Fasciola hepatica en mulares de Mendoza, Argentina

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    La fascioliasis es una enfermedad que se halla en expansión, tanto la causada por Fasciola hepatica, de distribución cosmopolita, como la causada por Fasciola gigantica, de zonas tropicales de África y Asia. A pesar de estar la fascioliasis ampliamente estudiada en rumiantes, son escasos los estudios en equinos. En Mendoza la enfermedad se ha diagnosticado en caballos, mulas y asnos. La morfología del huevo ha demostrado en humanos ser una herramienta diagnostica para diferenciar entre F. gigantica y F. hepatica. Los estudios de morfología de huevos son escasos en animales y prácticamente inexistentes en equinos. El mular, dada su actividad de transporte en alta montaña, actúa como dispersor del parásito

    Fascioliasis in working mules in endemic andean areas of Mendoza Province, Argentina

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    Fascioliasis, the affection caused by Fasciola sp. is an important livestock disease and major threat to human health (in Latin America only F. hepatica is present). Although fascioliasis is widely studied in several domestic species, in Argentina, the affection in equines, and particularly mules, is not even considered, thus not studied. Argentina has a quite remarkable tradition regarding mules, since they took part in every major event along the country history: from an intense commerce during colonialism with several neighbouring countries, crossing the Andes with the Ejército Libertador to fight against realists and liberate southern America from the Spanish oppression, to every transcendental conflict in the political conformation of such a wide and diverse nation

    Marine Ecoregion and Deepwater Horizon Oil Spill Affect Recruitment and Population Structure of a Salt Marsh Snail

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    Marine species with planktonic larvae often have high spatial and temporal variation in recruitment that leads to subsequent variation in the ecology of benthic adults. Using a combination of published and unpublished data, we compared the population structure of the salt marsh snail, Littoraria irrorata, between the South Atlantic Bight and the Gulf Coast of the United States to infer geographic differences in recruitment and to test the hypothesis that the Deepwater Horizon oil spill led to widespread recruitment failure of L. irrorata in Louisiana in 2010. Size-frequency distributions in both ecoregions were bimodal, with troughs in the distributions consistent with a transition from sub-adults to adults at ~13 mm in shell length as reported in the literature; however, adult snails reached larger sizes in the Gulf Coast. The ratio of sub-adults to adults was 1.5–2 times greater in the South Atlantic Bight than the Gulf Coast, consistent with higher recruitment rates in the South Atlantic Bight. Higher recruitment rates in the South Atlantic Bight could contribute to higher snail densities and reduced adult growth in this region. The ratio of sub-adults to adults in Louisiana was lower in 2011 than in previous years, and began to recover in 2012–2014, consistent with widespread recruitment failure in 2010, when large expanses of spilled oil were present in coastal waters. Our results reveal an important difference in the ecology of a key salt marsh invertebrate between the two ecoregions, and also suggest that the Deepwater Horizon oil spill may have caused widespread recruitment failure in this species and perhaps others with similar planktonic larval stages

    “Capacidad de transmisión de fasciola hepatica de lymnaeidos de la Provincia de Mendoza”

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    La fascioliasis es una enfermedad producida por trematodos hepáticos del género Fasciola (Trematoda: Fasciolidae), los cuales, para completar su ciclo, necesitan caracoles acuáticos de la familia Lymnaeidae. Esta enfermedad, no solo produce cuantiosas pérdidas a la ganadería, sino que también es una importante zoonosis que afecta a millones de personas en América, Europa, África, Asia y Oceanía

    Epidemiología de la fascioliasis y parasitosis regionales en Argentina.

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    La Fascioliasis, producida por Fasciola hepatica, afecta particularmente a rumiantes, produciendo graves pérdidas a la ganadería, y se considera una importante zoonosis, afectando a millones de personas en todo el mundo, con máximas endemias en países andinos. Al contar con un hospedador intermediario posee componentes ambientales que le dan características distintivas a cada región, y necesita un abordaje multidisciplinario

    Development of a nuclear test strategy for Test Program Element II

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    As part of Phase O in Test Program Element II of the Office of Fusion Energy's First Wall/Blanket/Shield Engineering Test Program, a test strategy has been developed to address the blanket/shield's (B/S's) thermal-hydraulic and thermomechanical data needs, which were identified in an earlier task through the use of nuclear and supporting nonnuclear testing. In Phase I, which extends through 1984, this strategy emphasizes the development of pre-design information and the nonnuclear supporting tests. After Phase I, nuclear testing will be emphasized, and B/S design-verification testing will become more important. The proposed program will investigate a solid-breeder-blanket concept via nuclear testing. This program can begin in Phase I with nonnuclear support tests, and can progress to integrated nuclear testing soon after the completion of Phase I. The program's approximate cost and schedule are presented. In addition, other possible areas of study for Phase I, and strategies for the use of nuclear and nonnuclear facilities after Phase I are outlined

    Limitations of Water Resources Infrastructure for Reducing Community Vulnerabilities to Extremes and Uncertainty of Flood and Drought

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    Debate and deliberation surrounding climate change has shifted from mitigation toward adaptation, with much of the adaptation focus centered on adaptive practices, and infrastructure development. However, there is little research assessing expected impacts, potential benefits, and design challenges that exist for reducing vulnerability to expected climate impacts. The uncertainty of design requirements and associated government policies, and social structures that reflect observed and projected changes in the intensity, duration, and frequency of water-related climate events leaves communities vulnerable to the negative impacts of potential flood and drought. The results of international research into how agricultural infrastructure features in current and planned adaptive capacity of rural communities in Argentina, Canada, and Colombia indicate that extreme hydroclimatic events, as well as climate variability and unpredictability are important for understanding and responding to community vulnerability. The research outcomes clearly identify the need to deliberately plan, coordinate, and implement infrastructures that support community resiliency.Fil: McMartin, Dena W.. University of Regina; CanadáFil: Hernani Merino, Bruno H.. University of Regina; CanadáFil: Bonsal, Barrie. Environment Canada; CanadáFil: Hurlbert, Margot. University of Regina; CanadáFil: Villalba, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Cientifícas y Tecnológicas; ArgentinaFil: Ocampo, Olga L.. Universidad Autónoma de Manizales; ColombiaFil: Upegui, Jorge Julián Vélez. Universidad Nacional de Colombia; ColombiaFil: Poveda, Germán. Universidad Nacional de Colombia; ColombiaFil: Sauchyn, David J.. University of Regina; Canad

    Complement C1 Esterase Inhibitor Levels Linked to Infections and Contaminated Heparin-Associated Adverse Events

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    Activation of kinin-kallikrein and complement pathways by oversulfated-chondroitin-sulfate (OSCS) has been linked with recent heparin-associated adverse clinical events. Given the fact that the majority of patients who received contaminated heparin did not experience an adverse event, it is of particular importance to determine the circumstances that increase the risk of a clinical reaction. In this study, we demonstrated by both the addition and affinity depletion of C1inh from normal human plasma, that the level of C1inh in the plasma has a great impact on the OSCS-induced kallikrein activity and its kinetics. OSCS-induced kallikrein activity was dramatically increased after C1inh was depleted, while the addition of C1inh completely attenuated kallikrein activity. In addition, actual clinical infection can lead to increased C1inh levels. Plasma from patients with sepsis had higher average levels of functional C1inh and decreased OSCS-induced kallikrein activity. Lastly, descriptive data on adverse event reports suggest cases likely to be associated with contaminated heparin are inversely correlated with infection. Our data suggest that low C1inh levels can be a risk factor and high levels can be protective. The identification of risk factors for contact system-mediated adverse events may allow for patient screening and clinical development of prophylaxis and treatments
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