Optimum Drift Velocity for Single Molecule Fluorescence Bursts in Micro/Nano-Fluidic Channels

Photonic burst histograms can be used to identify single protein molecules in micro/nano-fluidic channels provided the width of the histogram is narrow. Photonic shot noise and residence time fluctuations, caused by longitudinal diffusion, are the major sources of the histogram width. This Communication is a sequel to an earlier Letter of ours [L. L. Kish et al., Appl. Phys. Lett. 99, 143121 (2011)] and demonstrates that, for a given diffusion coefficient, an increase of the drift velocity enhances the relative shot noise and decreases the relative residence time fluctuations. This leads to an optimum drift velocity which minimizes the histogram width and maximizes the ability to identify single molecules, which is an important result for applications.Comment: 4 page

Identificación y análisis de los líderes de opinión en Twitter en torno a Hugo Chávez

Este artículo presenta los resultados de una investigación interdisciplinar realizada por varias universidades y departamentos de materias y campos de estudio diversos. Objetivos. Los objetivos son descubrir a los líderes de opinión en torno a la figura de Hugo Chávez creados en Twitter durante el período de la muestra, analizar el comportamiento de los usuarios de este espacio de microblogging y demostrar si en la actualidad se desarrolla una ciberdemocracia plena o la autocomunicación de masas. Metodología. En ella se han monitorizado todos los tuits que incluían los identificadores Chávez, Chavez, @chávez y @chavez en Twitter; se ha analizado el flujo de tuits diariamente desde el 5 de enero hasta el 13 de abril de 2013 (UTC/GMT - 4) y se ha conformado el mayor corpus de estos mensajes en lengua española sobre un tema político latinoamericano presentados en estudios científicos, con un total de 16.943.709 tuits y de 8.450.049 usuarios. Conclusión. Este estudio plantea que aún no existe una autocomunicación de masas plena.Publlicad

Identification and analysis of the opinion leaders around the figure of Hugo Chávez on Twitter

This article presents the results of an interdisciplinary research carried out by several universities and various departments specializing in different subjects and fields of study. Objetives. The aims are to identify the opinion leaders around the figure of Hugo Chávez on Twitter during the time of the sample, analyze user behavior in the microblogging space, and demonstrate whether full cyberdemocracy or mass self-communication are currently taking place. Results. The research has monitored all tweets which included the identifiers Chávez, Chavez, @chávez, @chavez on Twitter and has analyzed the daily flow of tweets from January 5 to April 13 2013 (UTC/ GMT – 4). Thus, with 19,943,709 tweets and 8,450,049 users, we have created the largest corpus of messages about a Latin-American political issue in Spanish ever presented by scientific research. Conclusions. This article demonstrates now full cyberdemocracy or mass self-communication are not currently taking place.Publicad

Investigating the trade-off between the effectiveness and efficiency of process modeling

Despite recent efforts to improve the quality of process models, we still observe a significant dissimilarity in quality between models. This paper focuses on the syntactic condition of process models, and how it is achieved. To this end, a dataset of 121 modeling sessions was investigated. By going through each of these sessions step by step, a separate ‘revision’ phase was identified for 81 of them. Next, by cutting the modeling process off at the start of the revision phase, a partial process model was exported for these modeling sessions. Finally, each partial model was compared with its corresponding final model, in terms of time, effort, and the number of syntactic errors made or solved, in search for a possible trade-off between the effectiveness and efficiency of process modeling. Based on the findings, we give a provisional explanation for the difference in syntactic quality of process models