Appearance of a late stage during mammalian DNA replication when cells resume formation of 10 kb DNA replication intermediates

AbstractAfter the joining of human large DNA replication intermediates and before the appearance of mature chromatin DNA, there exists a distinct stage — ‘the post-elongation stage’. This stage reappears during recovery of DNA synthesis simultaneously with the reappearance of a large DNA replication intermediate, 10 kb DNA

The Linkoping-Lund surgical experience with the HeartMate left ventricular assist system

Four transplant candidates fulfilling the Food and Drug Administration criteria for a permanent left ventricular assist device received a pneumatic HeartMate system as a bridge to heart transplantation. All patients survived and were fully rehabilitated at the time of transplantation, which was carried out 2 to 6 months after the initial operation. There were no major complications associated with the procedures. We are impressed by the effectiveness and safety of the device