A Mixed Heterobimetallic Y/Eu-MOF for the Cyanosilylation and Hydroboration of Carbonyls

Supplementary Materials The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/catal12030299/s1. Table S1: Elemental analysis of compounds Y/Eu-MOF. Table S2: ICP-AES results of compound Y/Eu-MOF. Table S3: Crystallographic data and structure refinement details of compound Y/Eu-MOF. Table S4: Selected bond lengths (Å) and angles (°) for compound Y/Eu-MOF. Table S5: Table of the continuous Shape Measurements for the MN3O6 coordination environment. Table S6: Table of the continuous Shape Measurements for the MO8 coordination environment. Table S7: Electrophoretic mobility and ζ-potential dependence, with the pH of the Y/Eu-MOFs particles dispersed in water. Conductivity fixed at 330 µS/cm. Table S8: Optimization of the reaction conditions in the hydroboration reaction. Table S9: Green metrics calculated for Y/Eu-MOF catalyst. Table S10: Catalytic cyanosilylation of benzaldehyde performances of Ln-MOFs, as reported in the literature. Figure S1: Figure of the pattern matching analysis and experimental PXRD for Y/Eu-MOF. Figure S2: Figure of the infrared spectra of the ligand and Y/Eu-MOF. Figure S3: SEM and EDS mapping of bulk material of Y/Eu-MOF. Figure S4: Images and particle size distribution (an overall of 250 particles) in the deposited fraction of Y/Eu-MOF catalyst non-suspended in water (about a 68% of the total amount), determined from optical microscope images. Figure S5: Images and particle size distribution (an overall of 250 particles) of Y/Eu-MOF crystals in the fraction steadily suspended in water (about a 32% of the total amount), determined from optical microscope images. Figure S6: Comparation of the particle size distribution of Y/Eu-MOF in the fraction steadily suspended in water and the non-suspended, determined from optical microscope images. Figure S7: Calibration line of conductivity (µS/cm) vs [NaCl] (mol/L). Figure S8: ζ-potential (mV) dependence with the pH of the Y/Eu-MOF. All the measurements were performed with constant conductivity of 330 µS/cm. Figure S9: Electrophoretic mobility (µm·cm/V·s) dependence with the pH of the Y/Eu-MOF. All the measurements were performed with constant conductivity of 330 µS/cm. Figure S10: Study of the recyclability of Y/Eu-MOF (0.5 mol%) catalyst on the cyanosilylation and hydroboration reaction of acetophenone as carbonyl substrate. Figure S11: Analysis of the TOF (h−1) obtained in the cyanosilylation reaction of acetophenone at different times of reaction with Y/Eu-MOF (0.5 mol%), with the optimized reaction conditions. Figure S12: Analysis of the TOF (h−1) obtained in the hydroboration reaction acetophenone at different times of reaction with Y/Eu-MOF (0.5 mol%), with the optimized reaction conditions. Scheme S1: Reaction conditions used for the study of recyclability of Y/Eu-MOF catalysts in the cyanosilylation reaction. Scheme S2: Reaction conditions used for the study of recyclability of Y/Eu-MOF catalysts in the hydroboration reaction. Scheme S3: Leaching test, carried out after the first and second cycles.Funding: This research has been funded by the State Research Agency (grants CTQ2017-84334-R and PGC2018-102052-B-C21) of the Spanish Ministry of Science, Innovation and Universities, the European Union (European Regional Development Fund—ERDF), Junta de Andalucía (P20_01041, UAL2020-AGR-B1781, B-FQM-734-UGR20 and FQM-394). E.E., S.R., and J.P. acknowledge the Government of the Basque Country, Juan de la Cierva Incorporación (grant no. IJC2019-038894-I) and University of Almeria (grant no. HIPATIA2021_04) for their respective fellowsHerein, to the best of our knowledge, the first heterobimetallic Y/Eu porous metal–organic framework (MOF), based on 3-amino-4-hydroxybenzoic acid (H2L) ligand, with the following formulae {[Y3.5Eu1.5L6(OH)3(H2O)3]·12DMF}n (in advance, namely Y/Eu-MOF), is described. The three-dimensional structure has been synthesized by solvothermal routes and thoroughly characterized, by means of single crystal X-ray diffraction, powder X-ray diffraction, electronic microscopy, ICP-AES, electrophoretic mobility, and FTIR spectra. Intriguingly, the porous nature allows for coordinated solvent molecules displacement, yielding unsaturated metal centers, which can act as a Lewis acid catalyst. This novel supramolecular entity has been tested in cyanosilylation and hydroboration reactions on carbonyl substrates of a diverse nature, exhibiting an extraordinary activity.Cierva Incorporación IJC2019-038894-IState Research Agency CTQ2017-84334-R, PGC2018-102052-B-C21University of Almeria HIPATIA2021_04Ministerio de Ciencia, Innovación y UniversidadesEuropean CommissionEuropean Regional Development FundJunta de Andalucía B-FQM-734-UGR20, FQM-394, IJC2019-038894-I, P20_01041, UAL2020-AGR-B178

Efficacy of Albumin Treatment for Patients with Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis

Background & aims: We performed a randomized trial to determine whether albumin should be administered to patients with infections unrelated to spontaneous bacterial peritonitis (SBP). Methods: We performed a multicenter, open-label trial in which 118 patients with cirrhosis, non-SBP infections, and additional risk factors for poor outcome were randomly assigned to receive antibiotics plus albumin (study group; n = 61) or antibiotics alone (control group; n = 57). The primary outcome was in-hospital mortality; secondary outcomes were effect of albumin on disease course. Results: There were no significant differences at baseline between groups in results from standard laboratory tests, serum markers of inflammation, circulatory dysfunction, or liver severity scores. However, the combined prevalence of acute on chronic liver failure (ACLF) and kidney dysfunction was significantly higher in the study group (44.3% vs 24.6% in the control group; P = .02), indicating greater baseline overall severity. There was no significant difference in the primary outcome between groups (13.1% in the study group vs 10.5% in the control group; P = .66). Circulatory and renal functions improved in only the study group. A significantly higher proportion of patients in the study group had resolution of ACLF (82.3% vs 33.3% in the control group; P = .03). A significantly lower proportion of patients in the study group developed nosocomial infections (6.6% vs 24.6% in the control group; P = .007). Conclusions: In a randomized trial of patients with advanced cirrhosis and non-SBP infections, in-hospital mortality was similar between those who received albumin plus antibiotics vs those who received only antibiotics (controls). However, patients given albumin were sicker at baseline and, during the follow-up period, a higher proportion had ACLF resolution and a lower proportion had nosocomial infections. ClinicalTrials.gov no: NCT02034279

A Mixed Heterobimetallic Y/Eu-MOF for the Cyanosilylation and Hydroboration of Carbonyls

Herein, to the best of our knowledge, the first heterobimetallic Y/Eu porous metal–organic framework (MOF), based on 3-amino-4-hydroxybenzoic acid (HL) ligand, with the following for-mulae {[YEuL (OH)(HO)]·12DMF} (in advance, namely Y/Eu-MOF), is described. The three-dimensional structure has been synthesized by solvothermal routes and thoroughly character-ized, by means of single crystal X-ray diffraction, powder X-ray diffraction, electronic microscopy, ICP-AES, electrophoretic mobility, and FTIR spectra. Intriguingly, the porous nature allows for coordinated solvent molecules displacement, yielding unsaturated metal centers, which can act as a Lewis acid catalyst. This novel supramolecular entity has been tested in cyanosilylation and hydroboration reactions on carbonyl substrates of a diverse nature, exhibiting an extraordinary activity.This research has been funded by the State Research Agency (grants CTQ2017-84334-R and PGC2018-102052-B-C21) of the Spanish Ministry of Science, Innovation and Universities, the European Union (European Regional Development Fund—ERDF), Junta de Andalucía (P20_01041, UAL2020-AGR-B1781, B-FQM-734-UGR20 and FQM-394). E.E., S.R., and J.P. acknowledge the Government of the Basque Country, Juan de la Cierva Incorporación (grant no. IJC2019-038894-I) and University of Almeria (grant no. HIPATIA2021_04) for their respective fellowships

Anales de Edafología y Agrobiología Tomo 43 Número 5-6

Suelos. Estudio de los minerales de la arcilla en unos perfiles de suelos con distintos contenidos en materia organica (Rasgos turbosos), de la Sierra de Guadarrama, por Jiménez Ballesta, R., Martín de Vidales, J. L., Reñones, O. y Gumuzzio, J.-- Distribución de la actividad ureásica en las unidades de estructura del suelo. II. Estado y comportamiento enzimático, por Pérez Mateos, M. y González Carcedo, S.-- Contribución al estudio de los suelos de la Sierra del Pozo (Jaén), por J. González Parra, C. González Huecos y A. López Lafuente.-- Influencia del suelo y métodos de cultivo sobre Longidorus profundorum. Nematodo fitoparasito de interés en las áreas cerealistas de la región central, por M. Fé Andrés y A. Bello.-- Aproximación paramétrica para la evaluación de la aptitud de las tierras, por Gilberto Hernández-Silva, Mariano Vinegas Soto, Mireya Maples Vermeersch y Lourdes Flores Delgadillo.-- Reacción con el FNa de los suelos de Galicia l. Características y significado del test de FNa. Distribución de la reactividad en función del material de partida, por E. García-Rodeja, F. MacÍas y F. Guitian Ojea.-- Naturaleza y propiedades del Humus subacuatico del embalse de Gasset (Ciudad Real), por G. Almendros, A. Polo y E. Dorado.-- Reacción con el FNa de los suelos de Galicia II. Suelos sobre rocas graníticas, por E. García-Rodeja Gayoso, F. Macías Vázquez, F. Guitián Ojea.-- Reacción con el FNa de los suelos de Galicia 111. Suelos formados sobre micaesquistos, pizarras, areniscas y cuarcitas, por E. García-Rodeja Gayoso, Macías Vázquez, F. y Guitián Ojea, F.—Fertilidad del Suelo. Effect o f nitrogen, phosphorus and crude organic matter on the yield and composition of potato and chilli, by K. R. Maurya and N. R. Dhar.-- Efecto de diferentes dosis de fertilización y abonamiento en el contenido y rendimiento de hierro y cobre en Lolium multiflorum lam. var. "Westerwolds", por David Flores-Román, Lourdes Flores-Delgadillo y Nicolás Aguilera-Herrera.-- Criterios para determinar la tolerancia a la salinidad de portainjertos de aguacates. por Díaz, A., Altares, M., Alvarez, C. E. y Fernández, .M.-- Estudio de la asimilabilidad de calcio por plantas de Ryegrass en un suelo tratado con compost urbano, por R. Nogales, F. Gallardo-Lara y M. Gómez.—Nutrición y Fisiología Vegetal. Cultivo de hipocotilos de Digitalis obscura L.: Relación entre morfogénesis y producción de glucosidos cardiotonicos, por M. C. Brisa, P. Pérez-Bermudez y J. Segura.-- Efecto del ácido 2,4-diclorofenoxiacético sobre la inducción de callos en cotiledones de Pinus Canariensis, por Pérez Francés, J. F., C. Martínez y A. C. Blesa.-- Desarrollo de técnicas de cultivo "in vitro" para la micopropagación de variedades de manzana sidrera, por Ricardo Ordas, Ana Rodríguez, Roberto Rodríguez y Ricardo Sánchez Tames.-- Caracterización estadística de limón, por F. A. Melendreras y A. Ortuño.-- Trabajos recapitulativos. Avances recientes en el estudio de las micorrizas V-A. II. Factores que afectan su formación y función y aplicaciones prácticas en agricultura, por C. Azcón-Aguilar, J. M. Barea y B. E. Roldán-Fajardo.-- El tiempo como factor formador del suelo, por M. Delgado Rodríguez y R. Delgado Calvo-Flores.-- Notas.-- BibliografíaPeer reviewe