Diseño y evaluación de un programa de informática aplicada a la investigación educativa

Este artículo presenta un estudio empírico de carácter evaluativo sobre el programa de la asignatura "Informática Aplicada a la Investigación Educativa". Esta materia surge en los nuevos planes de estudio de la Facultad de Ciencias de la Educación, concretamente como parte de la Licenciatura Pedagogía, y supone una respuesta del plan a la necesidad de formación científica en la actual Sociedad del Conocimiento, un aspecto que tiene escasa tradición en cuanto a propuestas curriculares. Ello justifica que abordemos tanto el contexto curricular y científico en que surge la materia, como la propuesta de programa de formación y su evaluación.This article presents an empiric study of evaluative character about the program proposed in Informática Aplicada a la Investigación Educativa. This matter arises on new sillabi of the ability of Sciences of the Education, specifically like part of the Licentiate of Pedagogy. It supposes an answer from the plan to the necessity of scientific formation in the current Society of the Knowledge, and it lacking tradition as for previous curricular proposals in this sense. This is justified that we approach the evaluative and scientific context, the proposal of formation and, its evaluation

Diagnóstico de necesidades de alfabetización digital para el trabajo científico en educación

Congreso virtua

Etiopathogenesis of ovarian cancer. An inflamm-aging entity?

Ovarian cancer is one of the most common gynecologic cancers and has the highest mortality rate. The risk/protective factors of ovarian cancer suggest that its etiology is multifactorial. Several factors are involved in age-related increases in carcinogenesis, including the accumulation of senescent cells, inflammaging (a chronic inflammatory state that persists in the elderly), and immunosenescence (aging of the immune system) changes associated with poor immune surveillance. At sites of inflammation, exposure to high levels of inflammatory mediators, such as reactive oxygen species, cytokines, prostaglandins, and growth factors, contributes to increased cell division and genetic and epigenetic changes. These exposure-induced changes promote excessive cell proliferation, increased survival, malignant transformation, and cancer development. Furthermore, the proinflammatory tumor microenvironment contributes to ovarian cancer metastasis and chemoresistance. This narrative review of the literature was carried out to delineate the possible role of inflammaging in the etiopathogenesis of ovarian cancer development. We discuss the current carcinogenic hypotheses, sites of origin, and etiological factors of ovarian cancer. Treatment of inflammation may represent an attractive strategy for both the prevention and therapy of ovarian cancer. © 2022 The Author(s

Carbon-supported statistically distributed polyethyleneimine/palladium (II) complexes as efficient and sustainable Sonogashira catalysts

We thank the Spanish Ministry of Science & Innovation, and the Junta de Andalucía for financial support (grants MAT2009-14185-C02-01, P09-FQM-4765 and a fellowship to A. Peñas). To CPL Carbon Link for kind donation of carbon samples. We also thank CICT of University of Jaén for technical facilities.A novel approach toward the obtaining of a Pd (II) carbon-supported catalyst based on a statistical distributed polymer (hyperbranched polyethyleneimine) and its use as a highly efficient and sustainable catalyst for Sonogashira-type coupling reactions is presented. The heterogenous Pd (II)/HBPEI catalyst fabricated through a facile, cost-effective and scalable procedure provides an innovative catalyst structure based on statistical distributed singular catalytic centers with well-defined Pd-Polymer chemical interactions, highly resistant to suffer leaching processes and extensively and homogenously distributed across the whole carbon surface. The catalyst exhibited excellent catalytic and recycling activity for several cross-coupling reactions between different aryl halides and terminal alkynes, free of any undesired by-product and in excellent yields, under air atmosphere, using water as solvent, at moderate temperatures (65 °C) and avoiding the use of phosphine derivatives, Cu(I) as co-catalyst and excess of any of the reactant. Therefore, the reported Pd(II)-HBPEI carbon-supported material can be considered a truly competitive heterogeneous Pd(II) catalyst for large-scale under green chemistry conditions.Spanish Ministry of Science & InnovationJunta de Andalucía MAT2009-14185-C02-01, P09-FQM-4765University of Jaén, CIC

Laboratory and telescope demonstration of the TP3-WFS for the adaptive optics segment of AOLI

AOLI (Adaptive Optics Lucky Imager) is a state-of-art instrument that combines adaptive optics (AO) and lucky imaging (LI) with the objective of obtaining diffraction limited images in visible wavelength at mid- and big-size ground-based telescopes. The key innovation of AOLI is the development and use of the new TP3-WFS (Two Pupil Plane PositionsWavefront Sensor). The TP3-WFS, working in visible band, represents an advance over classical wavefront sensors such as the Shack-Hartmann WFS (SH-WFS) because it can theoretically use fainter natural reference stars, which would ultimately provide better sky coverages to AO instruments using this newer sensor. This paper describes the software, algorithms and procedures that enabled AOLI to become the first astronomical instrument performing real-time adaptive optics corrections in a telescope with this new type of WFS, including the first control-related results at the William Herschel Telescope (WHT)This work was supported by the Spanish Ministry of Economy under the projects AYA2011-29024, ESP2014-56869-C2-2-P, ESP2015-69020-C2-2-R and DPI2015-66458-C2-2-R, by project 15345/PI/10 from the Fundación Séneca, by the Spanish Ministry of Education under the grant FPU12/05573, by project ST/K002368/1 from the Science and Technology Facilities Council and by ERDF funds from the European Commission. The results presented in this paper are based on observations made with the William Herschel Telescope operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias. Special thanks go to Lara Monteagudo and Marcos Pellejero for their timely contributions

Efecto terapéutico del afecto positivo

Resumen. La capacidad para regular las emociones de manera eficaz facilita la adaptación de las personas alámbito social y es uno de los elementos fundamentales para entender cómo las personas más resilientes son capacesde afrontar las situaciones adversas y salir reforzadas. El análisis de estas variables permitiría comprendermejor la relación que la literatura científica establece entre el estado afectivo positivo y una mejor salud física ymental. Uno de los aspectos más relevantes en esta relación son las habilidades para reconocer y expresar lasemociones, que permiten su fácil integración en programas de prevención y rehabilitación. Además, estas habilidadespodrían potenciarse en el contexto clínico a través de la mejora en la interacción emocional entre el personalsanitario y los pacientes, con un enfoque prioritario hacia la regulación de las emociones positivas.Summary. The ability to regulate emotions effectively makes it easier for individuals to adapt to their socialcontext, and it is one of the keys to understanding how the most resilient people are better able to cope with adversesituations and emerge from them stronger than before. An analysis of these variables would allow for a betterunderstanding of the relationship that previous scientific literature has established between positive emotionalstates and improved physical and mental health. Among the most important aspects of this relationship is anability to recognize and express emotions, which would indicate that these skills would be suitable for inclusionin prevention and rehabilitation programs. In addition, these abilities can be enhanced in the clinical contextthrough improved emotional interaction between health professionals and patients, aimed at fostering positiveemotion regulation

Oral microbiome and systemic antineoplastics in cancer treatment:a systematic review

Oral mucositis is one of the most common side effects in cancer patients receiving systemic antineoplastics. However, the underlying biological mechanisms leading to this condition are still unclear. For this reason, it has been hypothesised that systemic antineoplastics may cause an imbalance on the oral microbiota that subsequently triggers oral mucosa damage. A systematic review was performed following the PRISMA protocol and the PICO question established was: patients diagnosed with cancer, who are candidates for receiving systemic antineoplastics (P=Patients), that undergo oral microbiome determinations (I=Intervention), before and after systemic antineoplastics administration (C=Comparison), to analyse changes in the oral microbiome composition (O=Outcome). The bibliographic search was carried out in PubMed and other scientific repositories. Out of 166 obtained articles, only 5 met eligibility criteria. Acute myeloid leukaemia (AML) was the most frequent type of cancer (40 %) among the participants. Only one of the studies included a control group of healthy subjects. Heterogeneity in the protocols and approaches of the included studies hindered a detailed comparison of the outcomes. However, it was stated that a decrease in bacteria ? diversity is often associated with oral mucositis. On the other hand, fungal diversity was not associated with oral mucositis although ? diversity was lower at baseline on patients developing oral candidiasis. There is insufficient scientific evidence of oral microbiological changes in patients undergoing systemic antineoplastics. Further investigations ought to be carried out to identify microorganisms that might play a key role in the pathogenesis of oral mucosa damage in patients undergoing systemic antineoplastics

A Gamification-Based Intervention Program that Encourages Physical Activity Improves Cardiorespiratory Fitness of College Students: ‘The Matrix rEFvolution Program’

J.M.-G. was supported by the Spanish Ministry of Education, Culture and Sport under Grant FPU14/06837. I.E.-C. was supported by the Spanish Ministry of Science and Innovation under Grant FJCI-2014-19563. Additional support was obtained from the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence, Unit of Excellence on Exercise and Health (UCEES); and by the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades and European Regional Development Fund (ERDF) (Ref. SOMM17/6107/UGR)The aim of the present study was to examine the effects of a gamification-based program on cardiorespiratory fitness (CRF) levels of college students. We divided 112 college students into an intervention group (IG) and a control group (CG). IG college students followed a 15-week gamification-based program, whereas CG followed traditional lectures. CRF was assessed using the 20-meter shuttle-run test. CRF significantly improved after the program in the IG compared to CG (d ≤ 0.94, p < 0.001). Only participants of IG had significant CRF improvements (d ≤ 0.87, p < 0.001) between pre- and post-assessments. In the IG, from the students who attended 100% of lectures, 87.8% met physical activity recommendations for 100% of weeks, whereas from those who attended <100%, only 26.7% met them them for 100% of weeks (p < 0.001). Participants who met recommendations 100% of weeks had a significant CRF improvement (p < 0.001). Motivating college students throughout innovative teaching methods (e.g., gamification) can lead to health improvements.European Regional Development Fund (ERDF) (Ref. SOMM17/6107/UGR

Radionuclides in arctic marine macroalgae from Kongsfjorden (Svalbard)

Seaweeds are known to be useful environmental bioindicators since they bioaccumulate radioisotopes at very low environmental concentrations. Levels of natural radionuclides in six ecologically relevant brown and red seaweed species from Arctic coasts (Kongsfjorden, Spitsbergen, Svalbard Islands) were analysed in the present study, in order to characterise the levels of natural radioactivity in this ecosystem and to compare this with previously published data in coastal areas from other latitudes. Thalli were collected by SCUBA divers at different depths in Hansneset in September 2014 and transported immediately to the laboratory. Young thalli, free from macroscopic epibiota, were dried, powdered and confined in a standard geometry before gamma spectrometry measurements. Then, the radioactivity of 7Be, 40K, 208Tl, 210Pb, 212Pb, 226Ra and 228Ra was measured by high-resolution gamma spectrometry using high-purity germanium detectors for 172800 s. Detectors were calibrated using a traceable multi gamma standard source and results are on a dry weight and fresh weight basis and are decay corrected to the date of sampling. Our results revealed the influence of cosmogenic radionuclides in the intertidal zone, as shown by the unique presence of 7Be in the brown macroalga Fucus distichus, the only analysed species inhabiting the intertidal. High concentrations of 40K were observed in all species, as this is one of the essential elements in biota. Remarkably is the high content of 210Pb in the red seaweeds Phycodrys rubens and Ptilota gunneri, suggesting that these species might possess a higher capacity for heavy metals bioaccumulation than the analysed brown seaweeds