Characterization of electrical crosstalk in 4T-APS arrays using TCAD simulations

TCAD simulations have been conducted on a CMOS image sensor in order to characterize the electrical component of the crosstalk between pixels through the study of the electric field distribution. The image sensor consists on a linear array of five pinned photodiodes (PPD) with their transmission gates, floating diffusion and reset transistors. The effect of the variations of the thickness of the epitaxial layer has been addressed as well. In fact, the depth of the boundary of the epitaxial layer affects quantum efficiency (QE) so a correlation with crosstalk has been identified.Ministerio de Economía y Competitividad TEC2015-66878-C3-1RJunta de Andalucía TIC 2012-2338Office of Naval Research (USA) N00014141035

An Experimentally-Validated Verilog-A SPAD Model Extracted from TCAD Simulation

Single-photon avalanche diodes (SPAD) are photodetectors with exceptional characteristics. This paper proposes a new approach to model them in Verilog-A HDL with the help of a powerful tool: TCAD simulation. Besides, to the best of our knowledge, this is first model to incorporate a trap-assisted tunneling mechanism, a cross-section temperature dependence of the traps, and the self-heating effect. Comparison with experimental data establishes the validity of the model.Junta de Andalucía TIC 2012-2338Ministerio de Economía y Competitividad TEC2015-66878-C3-1-ROffice of Naval Research (USA) N00014141035

Diseño, intervención y propuesta de mejora para trabajar la coeducación en Educación Primaria

El Trabajo Fin de Grado que se muestra a continuación es una propuesta de intervención sobre “Coeducación”. Se trata de un tema que está a la orden del día, debido a la desigualdad entre hombres y mujeres existente en la sociedad. Se pretende fomentar la igualdad de género en las aulas para que en el futuro tengan un concepto diferente respecto al tema. En este proyecto el alumnado aprenderá el significado del concepto coeducación y todo lo que implica. La propuesta ha sido llevada a cabo con niños y niñas de 5º de Primaria de tres centros educativos de distintas zonas de Sevilla. En la presenta investigación se indican las actividades realizadas y las ideas de los discentes, así como un análisis de las mismas acompañado de sus respectivas conclusiones y propuestas de mejora.Universidad de Sevilla. Grado en Educación Primari

Parnaso español : coleccion de poesías escogidas de los mas célebres poetas castellanos

ÍndiceSign. : [calderón]8, 2[calderón]7, A-Z8, Aa-Ll8, Mm4Frisos tip. decorativos entre poemasViñeta xil. al final de la obraReclamosLa h. de grab. calc.: "M. S. Maella delt.", "M.S. Carmona sculpt."Contiene : Primeras tragedias españolas : Nise lastimosa y Nise laureada, Dª Ines de Castro y Valladares, Princesa de Portugal / compuestas por F. Geronimo Bermudez, p. 1-190. La venganza de Agamenon / tragedia de Sofocles, p. 191-250. Hecuba triste / tragedia de Euripides, p. 251-311. Isabela / tragedia de Lupercio Leonardo de Argensola, p. 312-420 ; Alejandra / tragedia del mismo autor [Lupercio Leonardo de Argensola], p. 421-52

Parnaso español : coleccion de poesías escogidas de los mas célebres poetas castellanos

ÍndiceSign.: a7, b8, c6, A-Z8, Aa-Dd8, Ee9Frisos tip. al ppio. de los poemasReclamosLas h. de grab. calc.: "Manl. Salvor. Carmona lo gravó" representa un retrato de Juan de la Cueva y "Joac. Jph. Fabregát lo grabo" un retrato de Francisco de Rioj

Simulation for training in sinus floor elevation : new surgical bench model

Objectives: to describe a bench model (workshop of abilities) for sinus floor elevation (SFE) training that simulates the surgical environment and to assess its effectiveness in terms of trainees? perception. Study design: thirty-six randomly selected postgraduate students entered this cross-sectional pilot study and asked to fill in an anonymous, self-applied, 12-item questionnaire about a SFE workshop that included a study guide containing the workshop?s details, supervised practice on a simulated surgical environment, and assessment by means of specific check-lists. Results: Thirtiy-six fresh sheep heads were prepared to allow access to the buccal vestible. Using the facial tuber, third premolar and a 3D-CT study as landmarks for trepanation, the sinus membrane was lifted, the space filled with ceramic material and closed with a resorbable membrane. The participants agreed on their ability to perform SFE in a simulated situation (median score= 4.5; range 2-5) and felt capable to teach the technique to other clinicians or to undertake the procedure for a patient under supervision of an expert surgeon (median= 4; range 1-5 ). There were no differences on their perceived ability to undertake the technique on a model or on a real patient under supervision of an expert surgeon (p=0.36). Conclusions: Clinical abilities workshops for SFE teaching are an essential educational tool but supervised clinical practice should always precede autonomous SFE on real patients. Simulation procedures (workshop of abilities) are perceived by the partakers as useful for the surgical practice. However, more studies are needed to validate the procedure and to address cognitive and communication skills, that are clearly integral parts of surgical performance

Parnaso español : coleccion de poesías escogidas de los mas célebres poetas castellanos ; tomo II

El recopilador de la obra es Juan José López Sedano, seud. del P. Pedro EstalaSign. : [calderón]8, 2[calderón]8, A-Z8, Aa8ReclamosLas h. de grab. calc.: "Manl. Salvor. Carmona lo Gravó", representan los retratos de Garcilaso de la Vega y de Alonso de Ercill

Factors related to late stage diagnosis of oral squamous cell carcinoma

Aims: To identify factors related to advanced-stage diagnosis of oral cancer to disclose high-risk groups and facilitate early detection strategies. Study design: An ambispective cohort study on 88 consecutive patients treated from January 1998 to December 2003. Inclusion criteria: pathological diagnosis of OSCC (primary tumour) at any oral site and suffering from a tumour at any TNM stage. Variables considered: age, gender, smoking history, alcohol usage, tumour site, macroscopic pattern of the lesion, co-existing precancerous lesion, degree of differentiation, diagnostic delay and TNM stage. Results: A total of 88 patients (mean age 60±11.3; 65.9% males) entered the study. Most patients (54.5%) suffered no delayed diagnosis and 45.5% of the carcinomas were diagnosed at early stages (I-II). The most frequent clinical lesions were ulcers (70.5%). Most cases were well- and moderately-differentiated (91%). Univariate analyses revealed strong associations between advanced stages and moderate-poor differentiation (OR=4.2; 95%CI=1.6-10.9) or tumour site (floor of the mouth (OR=3.6; 95%CI=1.2-11.1); gingivae (OR=8.8; 95%CI=2.0-38.2); and retromolar trigone (OR=8.8; 95%CI=1.5-49.1)). Regression analysis recognised the site of the tumour and the degree of differentiation as significantly associated to high risk of late-stage diagnosis. Conclusions: Screening programmes designed to detect asymptomatic oral cancers should be prioritized. Educational interventions on the population and on the professionals should include a sound knowledge of the disease presentation, specifically on sites like floor of the mouth, gingivae and retromolar trigone. More studies are needed in order to analyse the part of tumour biology on the extension of the disease at the time of diagnosis. © Medicina Oral S. L

Parasympathetic Tone Changes in Anesthetized Horses after Surgical Stimulation, and Morphine, Ketamine, and Dobutamine Administration

Autonomic nervous system (ANS) activity can modify cardiovascular parameters in response to nociceptive stimuli or drugs in anesthetized animals. The aim of this study was to determine if a surgical nociceptive stimulus and morphine, ketamine, and dobutamine administration would modify ANS activity observed as a change in the mean parasympathetic tone activity (PTAm) in anesthetized horses. In 20 anesthetized horses, heart rate (HR), mean arterial pressure (MAP), and PTAm were monitored before and 1, 3, and 5 min after surgical incision, and before and 10 min after the administration of morphine (0.2 mg/kg IV). If nystagmus or spontaneous ventilation was observed, ketamine (0.5 mg/kg IV) was given, and the three variables were registered before and 3 and 5 min afterward. If MAP reached ≤ 62 mmHg, a dobutamine infusion was administered, and the three variables were recorded before and 5 min after starting/increasing the infusion (0.25 μg/kg/min IV every 5 min). The three variables were registered before and 1, 3, and 5 min after a PTAm decrease of ≥ 20%, HR increase of ≥ 10%, or MAP increase of ≥ 20%. The PTAm decreased 3 min after the administration of ketamine and 1 min after a PTA event. The surgical incision, dobutamine, and morphine did not modify PTAm. The absence of changes in ANS activity after the nociceptive stimulus and lack of correlation between PTAm and HR or MAP suggest that PTAm is a poor indicator of sympathetic activation under the study conditions. Ketamine seems to affect ANS activity by decreasing PTAm