QUIJOTE scientific results -- XIII. Intensity and polarization study of supernova remnants in the QUIJOTE-MFI wide survey: CTB 80, Cygnus Loop, HB 21, CTA 1, Tycho and HB 9

We use the new QUIJOTE-MFI wide survey (11, 13, 17 and 19 GHz) to produce spectral energy distributions (SEDs), on an angular scale of 1 deg, of the supernova remnants (SNRs) CTB 80, Cygnus Loop, HB 21, CTA 1, Tycho and HB 9. We provide new measurements of the polarized synchrotron radiation in the microwave range. For each SNR, the intensity and polarization SEDs are obtained and modelled by combining QUIJOTE-MFI maps with ancillary data. In intensity, we confirm the curved power law spectra of CTB 80 and HB 21 with a break frequency $\nu_{\rm b}$ at 2.0$^{+1.2}_{-0.5}$ GHz and 5.0$^{+1.2}_{-1.0}$ GHz respectively; and spectral indices respectively below and above the spectral break of $-0.34\pm0.04$ and $-0.86\pm0.5$ for CTB 80, and $-0.24\pm0.07$ and $-0.60\pm0.05$ for HB 21. In addition, we provide upper limits on the Anomalous Microwave Emission (AME), suggesting that the AME contribution is negligible towards these remnants. From a simultaneous intensity and polarization fit, we recover synchrotron spectral indices as flat as $-0.24$, and the whole sample has a mean and scatter of $-0.44\pm0.12$. The polarization fractions have a mean and scatter of $6.1\pm1.9$\%. When combining our results with the measurements from other QUIJOTE studies of SNRs, we find that radio spectral indices are flatter for mature SNRs, and particularly flatter for CTB 80 ($-0.24^{+0.07}_{-0.06}$) and HB 21 ($-0.34^{+0.04}_{-0.03}$). In addition, the evolution of the spectral indices against the SNRs age is modelled with a power-law function, providing an exponent $-0.07\pm0.03$ and amplitude $-0.49\pm0.02$ (normalised at 10 kyr), which are conservative with respect to previous studies of our Galaxy and the Large Magellanic Cloud.Comment: 33 pages, 15 figure, 15 tables. Submitted to MNRAS. QUIJOTE data maps available at https://research.iac.es/proyecto/quijot

QUIJOTE scientific results - X. Spatial variations of anomalous microwave emission along the Galactic plane

Anomalous microwave emission (AME) is an important emission component between 10 and 60 GHz that is not yet fully understood. It seems to be ubiquitous in our Galaxy and is observed at a broad range of angular scales. Here we use the new QUIJOTE-MFI wide survey data at 11, 13, 17, and 19 GHz to constrain the AME in the Galactic plane (|b| < 10°) on degree scales. We built the spectral energy distribution between 0.408 and 3000 GHz for each of the 5309 0.9° pixels in the Galactic plane, and fitted a parametric model by considering five emission components: synchrotron, free–free, AME, thermal dust and CMB anisotropies. We show that not including QUIJOTE-MFI data points leads to the underestimation (up to 50 per cent) of the AME signal in favour of free–free emission. The parameters describing these components are then intercompared, looking for relations that help to understand AME physical processes. We find median values for the AME width, WAME, and for its peak frequency, νAME, respectively of 0.560−0.050+0.059 and 20.7−1.9+2.0 GHz, slightly in tension with current theoretical models. We find spatial variations throughout the Galactic plane for νAME, but only with reduced statistical significance. We report correlations of AME parameters with certain ISM properties, such as that between the AME emissivity (which shows variations with the Galactic longitude) and the interstellar radiation field, and that between the AME peak frequency and dust temperature. Finally, we discuss the implications of our results on the possible molecules responsible for AME.We thank the staff of the Teide Observatory for invaluable assistance in the commissioning and operation of QUIJOTE. The QUIJOTE experiment is being developed by the Instituto de Astrofisica de Canarias (IAC), the Instituto de Fisica de Cantabria (IFCA), and the Universities of Cantabria, Manchester and Cambridge. Partial financial support was provided by the Spanish Ministry of Science and Innovation under the projects AYA2007-68058-C03-01, AYA2007-68058-C03-02, AYA2010-21766-C03-01, AYA2010-21766-C03-02, AYA2014-60438-P, ESP2015-70646-C2-1-R, AYA2017-84185-P, ESP2017-83921-C2-1-R, PID2019-110610RB-C21, PID2020-120514GB-I00, IACA13-3E-2336, IACA15-BE-3707, EQC2018-004918-P, the Severo Ochoa Programs SEV-2015-0548 and CEX2019-000920-S, the Maria de Maeztu Program MDM-2017-0765 and by the Consolider-Ingenio project CSD2010-00064 (EPI: Exploring the Physics of Inflation). We acknowledge support from the ACIISI, Consejeria de Economia, Conocimiento y Empleo del Gobierno de Canarias and the European Regional Development Fund (ERDF) under grant with reference ProID2020010108. This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement number 687312 (RADIOFOREGROUNDS). We thank the anonymous referee whose comments helped to improve this work. We also thank Bruce Draine, Brandon Hensley, and Enrique Fernández Cancio for their useful comments. MFT acknowledges support from the Agencia Estatal de Investigación (AEI) of the Ministerio de Ciencia, Innovación y Universidades (MCIU) and the European Social Fund (ESF) under grant with reference PRE-C-2018-0067. SEH acknowledges support from the STFC Consolidated Grant (ST/P000649/1). FP acknowledges support from the Spanish State Research Agency (AEI) under grant number PID2019-105552RB-C43 and support from the Agencia Canaria de Investigación, Innovación y Sociedad de la Información (ACIISI) under the European FEDER (FONDO EUROPEO DE DESARROLLO REGIONAL) de Canarias 2014-2020 grant No. PROID2021010078. This paper made use of the IAC Supercomputing facility HTCONDOR (http://research.cs.wisc.edu/htcondor/), partly financed by the Ministry of Economy and Competitiveness with FEDER funds, code IACA13-3E-2493. We acknowledge the use of the Legacy Archive for Microwave Background Data Analysis (LAMBDA), part of the High Energy Astrophysics Science Archive Center (HEASARC). HEASARC/LAMBDA is a service of the Astrophysics Science Division at the NASA Goddard Space Flight Center. We acknowledge the use of data provided by the Centre d’Analyse de Données Etendues (CADE), a service of IRAP-UPS/CNRS [http://cade.irap.omp.eu, Paradis et al. (2012)]. This research has made use of the SIMBAD data base, operated at CDS, Strasbourg, France (Wenger et al. 2000). This work has made use of S-band Polarisation All Sky Survey (S-PASS) data. Based on observations obtained with Planck (http://www.esa.int/Planck), an ESA science mission with instruments and contributions directly funded by ESA Member States, NASA, and Canada. Some of the presented results are based on observations obtained with the QUIJOTE experiment (http://research.iac.es/proyecto/quijote). Some of the results in this paper have been derived using the healpy and HEALPIX packages (Górski et al. 2005; Zonca et al. 2019). We have also used SCIPY (Virtanen et al. 2020), EMCEE (Foreman-Mackey et al. 2013), NUMPY (Harris et al. 2020), MATPLOTLIB (Hunter 2007), CORNER (Foreman-Mackey 2016), and ASTROPY (Astropy Collaboration 2013, 2018) PYTHON packages

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Clinical Presentation and Short- and Long-term Outcomes in Patients With Isolated Distal Deep Vein Thrombosis vs Proximal Deep Vein Thrombosis in the RIETE Registry

International audienceImportance: Insufficient data exist about the clinical presentation, short-term, and long-term outcomes of patients with isolated distal deep vein thrombosis (IDDVT), that is, thrombosis in infrapopliteal veins without proximal extension or pulmonary embolism (PE).Objective: To determine the clinical characteristics, short-term, and 1-year outcomes in patients with IDDVT and to compare the outcomes in unadjusted and multivariable adjusted analyses with patients who had proximal DVT.Design, setting, and participants: This was a multicenter, international cohort study in participating sites of the Registro Informatizado Enfermedad Tromboembólica (RIETE) registry conducted from March 1, 2001, through February 28, 2021. Patients included in this study had IDDVT. Patients with proximal DVT were identified for comparison. Patients were excluded if they had a history of asymptomatic DVT, upper-extremity DVT, coexisting PE, or COVID-19 infection.Main outcomes and measures: Primary outcomes were 90-day and 1-year mortality, 1-year major bleeding, and 1-year venous thromboembolism (VTE) deterioration, which was defined as subsequent development of proximal DVT or PE.Results: A total of 33 897 patients were identified with isolated DVT (without concomitant PE); 5938 (17.5%) had IDDVT (mean [SD] age, 61 [17] years; 2975 male patients [50.1%]), and 27 959 (82.5%) had proximal DVT (mean [SD] age, 65 [18] years; 14 315 male patients [51.2%]). Compared with individuals with proximal DVT, those with IDDVT had a lower comorbidity burden but were more likely to have had recent surgery or to have received hormonal therapy. Patients with IDDVT had lower risk of 90-day mortality compared with those with proximal DVT (odds ratio [OR], 0.47; 95% CI, 0.40-0.55). Findings were similar in 1-year unadjusted analyses (hazard ratio [HR], 0.52; 95% CI, 0.46-0.59) and adjusted analyses (HR, 0.72; 95% CI, 0.64-0.82). Patients with IDDVT had a lower 1-year hazard of VTE deterioration (HR, 0.83; 95% CI, 0.69-0.99). In 1-year adjusted analyses of patients without an adverse event within the first 3 months, IDDVT was associated with lower risk of VTE deterioration (adjusted HR, 0.48; 95% CI, 0.24-0.97). By 1-year follow-up, symptoms or signs of postthrombotic syndrome were less common in patients with IDDVT (47.6% vs 60.5%).Conclusions and relevance: Results of this cohort study suggest that patients with IDDVT had a less ominous prognosis compared with patients with proximal DVT. Such differences were likely multifactorial, including the differences in demographics, risk factors, comorbidities, particularly for all-cause mortality, and a potential association of thrombus location with VTE deterioration and postthrombotic syndrome. Randomized clinical trials are needed to assess the optimal long-term management of IDDVT