886 research outputs found
Scaling Solutions and reconstruction of Scalar Field Potentials
Starting from the hypothesis of scaling solutions, the general exact form of
the scalar field potential is found. In the case of two fluids, it turns out to
be a negative power of hyperbolic sine. In the case of three fluids the
analytic form is not found, but is obtained by quadratures.Comment: 5 pages, 2 figures, some changes in references and figures caption
Algorithmic procedures for Bayesian MEG/EEG source reconstruction in SPM
AbstractThe MEG/EEG inverse problem is ill-posed, giving different source reconstructions depending on the initial assumption sets. Parametric Empirical Bayes allows one to implement most popular MEG/EEG inversion schemes (Minimum Norm, LORETA, etc.) within the same generic Bayesian framework. It also provides a cost-function in terms of the variational Free energy—an approximation to the marginal likelihood or evidence of the solution. In this manuscript, we revisit the algorithm for MEG/EEG source reconstruction with a view to providing a didactic and practical guide. The aim is to promote and help standardise the development and consolidation of other schemes within the same framework. We describe the implementation in the Statistical Parametric Mapping (SPM) software package, carefully explaining each of its stages with the help of a simple simulated data example. We focus on the Multiple Sparse Priors (MSP) model, which we compare with the well-known Minimum Norm and LORETA models, using the negative variational Free energy for model comparison. The manuscript is accompanied by Matlab scripts to allow the reader to test and explore the underlying algorithm
Aplicación de técnicas SIG en el estudio de evaluación de degradación de suelos. Mazarrón (Murcia)
El objetivo general de este estudio ha sido evaluar el estado actual y los cambios que se han producido en
algunas características edáficas del área de Mazarrón (Murcia) en un periodo de 20 años, en relación con los
procesos de degradación. Para ello se han utilizado los resultados de dos muestreos de suelos realizados en
un intervalo de veinte años (1988 y 2008). Se han analizado algunas de las características edáficas que más
relación tienen con la vulnerabilidad de los suelos a la erosión (Textura, Materia orgánica y Pedregosidad) y de
las cuales se disponía de datos en los dos muestreos.
Para la creación y análisis de la información espacial se han empleado dos Sistemas de Información
Geográfica de software libre. Uno de ellos ha sido GvSIG, desarrollado por la Generalitat Valenciana y el
programa GRASS. La metodología SIG empleada ha sido una herramienta fundamental para obtener la serie
de capas de variables edáficas para los años 1988 y 2008.
Los resultados muestran como el área de estudio es bastante vulnerable a los procesos erosivos, sobre
todo por erosión hidrica y antrópica, debido a las características de sus suelos. Riesgo que se incrementaría si
en futuro se abandonaran los cultivos.The main objetive of these study is to evaluate the current situation and the changes ocurred in some
edaphic characteristics of the soils in the Mazarrón area (Murcia) in a twenty years period, in relation with the
degradation processes. For these propose we have used the results of two soils samples carried out in a
twenty years intervale (1988 and 2008). The caracteristics more related with the vulnerability of the soil
erosion (texture, organic matter and stoniness) of wich we had data of the two samples were evaluated.
Two Geografical Information System of free software have been used for the creation and analisis of the
espacial information. One of these was GvSIG, developed by Generalitat Valenciana and GRASS programme.
The GIS methodology carried out was a fundamental tool to obtain edaphic variables layers for the years 1988
and 2008.
The results show how the study area is very sensible to the erosive processes, specialy by hidric and
antropic erosion, because soil caracteristics. This hazard would increase in a future if the land was
abandoned
Diversity and distribution of blackflies (Diptera: Simuliidae) of the Tormes river basin (western Spain)
To enhance the partial knowledge on blackfly (Diptera: Simuliidae) fauna in Spain it is crucial to collect all the available data on this group to better understand their ecology and distribution over the years. This study presents data from samples collected along the Tormes river basin (western Spain) during the years 1988, 1989 and 1996 and then stored at the University of Salamanca. As a result of a research stay, a total of 19 species belonging to 3 genera (Prosimulium, Metacnephia and Simulium) and 5 Simulium subgenera (Boophthora, Eusimulium, Nevermannia, Simulium and Wilhelmia) were identified after examining 64% of the stored material, representing 35% of the species known from Spain. In addition, 14 species are reported for the first time in 3 provinces in the study area. Further sampling of blackflies is foreseen in the near future in order to check if the blackfly fauna composition determined in samples collected during the last two decades of the 20th century has changed. This aim gains in importance as a consequence of haematophagous species having been found, relevant for both public health and animal welfare, not only because of the discomfort caused by their bites but also because of their potential as vectors of disease-causing agents in animals and humans
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
Numerous epidemiological and preclinical studies suggest that flavonoids may play an important role in the decreased risk of cancer associated with a diet rich in plant-derived foods. In this article, we have reviewed the epidemiological studies assessing the relationship between the consumption of three of the most common flavonoids, i.e. quercetin, luteolin and kaempferol, and the risk of developing cancer. We have also performed a meta-analysis on the consumption of these three flavonoids (alone and combined) and overall risk of cancer. The analysis of data from 18 case-control studies (8585 cases with cancer and 9975 control subjects) revealed that a high consumption of these three flavonoids (combined) was associated with a statistically significant reduction of overall cancer risk (OR: 0.73; 95% CI: 0.63, 0.84; p<0.01). A reduction of overall cancer risk was also observed for quercetin (OR: 0.73; 95% CI: 0.62, 0.86; p<0.01), kaempferol (OR: 0.86; 95% CI: 0.73, 1.11; p>0.05) and luteolin (OR: 0.90; 95% CI: 0.69, 1.18; p>0.05), which was statistically significant for quercetin. A high intake of these three flavonoids (combined) was also associated with a statistically significant reduction of lung cancer risk (OR: 0.67; 95% CI: 0.49, 0.91; p<0.05) and colon cancer risk (OR: 0.75; 95% CI: 0.57, 0.98; p<0.05). The analysis of data from 14 cohort studies (385033 individuals and 10809 cancer cases) showed a statistically significant reduction of overall cancer risk for the three flavonoids combined (RR: 0.89; 95% CI: 0.80, 1.00; p<0.05), for quercetin (RR: 0.82; 95% CI: 0.71, 0.96; p<0.05) and for kaempferol (RR: 0.88; 95% CI: 0.78, 0.99; p<0.05), and a non-statistically significant reduction for luteolin (RR: 0.95; 95% CI: 0.67, 1.34; p>0.05). These results suggest that consumption of foods rich in the flavonoids quercetin, kaempferol and luteolin may reduce the risk of developing cance
Mediterranean Diet and Endothelial Function: A Review of Its Effects at Different Vascular Bed Levels
The Mediterranean diet has recently been the focus of considerable attention as a palatable model of a healthy diet. Its influence on many cardiovascular risk factors, combined with its proven effect in reducing the risk of cardiovascular events in primary prevention, has boosted scientific interest in this age-old nutritional model. Many of the underlying mechanisms behind its health-giving effects have been revealed, from the modulation of the microbiota to the function of high-density lipoproteins (HDL), and it seems to deliver its health benefits mainly by regulating several key mechanisms of atherosclerosis. In this review, we will review the evidence for its regulation of endothelial function, a key element in the early and late stages of atherosclerosis. In addition, we will assess studies which evaluate its effects on the functioning of different arterial territory vessels (mainly the microvascular, peripheral and central vascular beds), focusing mainly on the capillary, brachial and carotid arteries. Finally, we will evaluate the molecular mechanisms which may be involved
Different Dietary Approaches, Non-Alcoholic Fatty Liver Disease and Cardiovascular Disease: A Literature Review
Non-alcoholic fatty liver disease (NAFLD) is the first cause of chronic liver disease and is also associated with other harmful entities such as obesity, metabolic syndrome, dyslipidemia, and diabetes. NAFLD is a significant public health concern worldwide, impacting individuals of all ages, and its prevalence is projected to increase in the near future due to its connection with obesity. Intrinsic (genetics) and external (lifestyle) factors may also modulate NAFLD, and, in turn, may partly explain the observed relationship between NAFLD and cardiovascular disease (CVD). Although many drugs are been tested to treat NAFLD, to date, no drug has indication to specifically treat this disorder. Thus, the current management of NAFLD relies on lifestyle modifications and specifically on weight loss, physical activity, and the intake of a healthy diet. In the present narrative review, we will discuss the effects of certain dietary patterns on NAFLD incidence and progression
Configuration Complexities of Hydrogenic Atoms
The Fisher-Shannon and Cramer-Rao information measures, and the LMC-like or
shape complexity (i.e., the disequilibrium times the Shannon entropic power) of
hydrogenic stationary states are investigated in both position and momentum
spaces. First, it is shown that not only the Fisher information and the
variance (then, the Cramer-Rao measure) but also the disequilibrium associated
to the quantum-mechanical probability density can be explicitly expressed in
terms of the three quantum numbers (n, l, m) of the corresponding state.
Second, the three composite measures mentioned above are analytically,
numerically and physically discussed for both ground and excited states. It is
observed, in particular, that these configuration complexities do not depend on
the nuclear charge Z. Moreover, the Fisher-Shannon measure is shown to
quadratically depend on the principal quantum number n. Finally, sharp upper
bounds to the Fisher-Shannon measure and the shape complexity of a general
hydrogenic orbital are given in terms of the quantum numbers.Comment: 22 pages, 7 figures, accepted i
Reconstructing anatomy from electro-physiological data
Here we show how it is possible to make estimates of brain structure based on MEG data. We do this by reconstructing functional estimates onto distorted cortical manifolds parameterised in terms of their spherical harmonics. We demonstrate that both empirical and simulated MEG data give rise to consistent and plausible anatomical estimates. Importantly, the estimation of structure from MEG data can be quantified in terms of millimetres from the true brain structure. We show, for simulated data, that the functional assumptions which are closer to the functional ground-truth give rise to anatomical estimates that are closer to the true anatomy
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