Locus of Control and Support for or Opposition to Concealed Carry on Campus: A Correlational Study

Graduate Applie

Predicting Dissertation Methodology Choice among Doctoral Candidates at a Faith-Based University

Limited research has investigated dissertation methodology choice and the factors that contribute to this choice. Quantitative research is based in mathematics and scientific positivism, and qualitative research is based in constructivism. These underlying philosophical differences posit the question if certain factors predict dissertation methodology choice. Using the theoretical framework of intersectionality, this predictive, correlational study used archival data to determine if biological sex, ethnicity, age, or religious affiliation predicts dissertation methodology choice. A logistics regression analysis was used to review 398 doctoral dissertations and determine if any of the criterion variables predicted dissertation methodology choice. After analysis, it was determined that none of the criterion variables of biological sex, ethnicity, age, and religious affiliation were statistically significant in predicting dissertation methodology choice. Keywords: doctoral dissertation, research methodology, quantitative research, qualitative researc

Twin-Screw Extrusion Processing of Distillers Dried Grains with Solubles (DDGS)-Based Yellow Perch (Perca flavescens) Feeds

Increases in global aquaculture production, compounded with limited availabilities of fish meal for fish feed, has created the need for alternative protein sources. Twinscrew extrusion studies were performed to investigate the production of nutritionally balanced feeds for juvenile yellow perch (Perca flavescens). Five isocaloric (~3.06 kcal/g) ingredient blends, adjusted to a target protein content of 36.7% db, were formulated with 0%, 10%, 20%, 30%, and 40% distillers dried grains with solubles (DDGS) at an initial moisture content of 5–7%db, with appropriate amounts of fish meal, fish oil, whole wheat flour, corn gluten meal, and vitamin and mineral premixes. During processing, varying amounts of steam (6.9–9.7 kg/h) were injected into the conditioner and water (6.7–13.1 kg/h) into the extruder to modulate the cohesiveness of the final extrudates. Extrusion cooking was performed at 226–298 rpm using a 1.9 mm die. Mass flow rate and processing temperatures generally decreased with progressively higher DDGS content. Moisture content, water activity, unit density, bulk density, expansion ratio, compressive strength and modulus, pellet durability index, water stability, angle of repose, and color were extensively analyzed to quantify the effects of varying DDGS content on the physical properties of the final extrudates. Significant differences (P\u3c0.05) among the blends were observed for color and bulk density for both the raw and extruded material, respectively, and for the unit density of the extruded product. There were also significant changes in brightness (L), redness (a), and yellowness (b) among the final products when increasing the DDGS content of the blends. Expansion ratio and compressive strength of the extrudates were low. On the other hand, all extruded diets resulted in very good water stability properties and nearly all blends achieved high pellet durability indices. In summary, each of the ingredient blends resulted in viable extrudates

Usage of Indiana University computation and data cyberinfrastructure in FY 2011/2012 and assessment of future needs

This report details the past and current cyberinfrastructure resources that have been deployed by the Research Technologies (RT) division of University Information Technologies Services to support research and scholarly activities at IU. This report also presents data and detailed analysis of system usage and services supported by RT for the FY 2011/2012 period, projects future usage trends based on these data, and provides several recommendations for the most effective ways to meet the growing need for high performance computing resources in research and scholarly endeavors.This research was supported in part by: The Pervasive Technology Institute, Indiana Metabolomics and Cytomics Initiative, and the Indiana Genomics Initiative. All of these initiatives have been supported in part by Lilly Endowment, Inc. Grant number 1U24AA014818-01 from NIAAA/NIH. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIAAA/NIH. National Science Foundation under Grants CDA-9601632, EIA-0116050, ACI-0338618l, OCI-0451237, OCI-0535258, and OCI-0504075, CNS-0723054, and CNS-0521433. Shared University Research grants from IBM, Inc. to Indiana University. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the funding agencies represented above

Performance study of the ablative Z-pinch pulsed plasma thruster

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76691/1/AIAA-2001-3898-280.pd

Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases

Alzheimer’s disease (AD) is a complex, multifactorial disease in which different neuropathological mechanisms are likely involved, including those associated with pathological tau and Aβ species as well as neuroinflammation. In this context, the development of single multitargeted therapeutics directed against two or more disease mechanisms could be advantageous. Starting from a series of 1,5-diarylimidazoles with microtubule (MT)-stabilizing activity and structural similarities with known NSAIDs, we conducted structure−activity relationship studies that led to the identification of multitargeted prototypes with activities as MT-stabilizing agents and/or inhibitors of the cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) pathways. Several examples are brain-penetrant and exhibit balanced multitargeted in vitro activity in the low μM range. As brain-penetrant MT-stabilizing agents have proven effective against tau-mediated neurodegeneration in animal models, and because COX- and 5-LOX-derived eicosanoids are thought to contribute to Aβ plaque deposition, these 1,5-diarylimidazoles provide tools to explore novel multitargeted strategies for AD and other neurodegenerative diseases

On the Vacuum energy of a Color Magnetic Vortex

We calculate the one loop gluon vacuum energy in the background of a color magnetic vortex for SU(2) and SU(3). We use zeta functional regularization to obtain analytic expressions suitable for numerical treatment. The momentum integration is turned to the imaginary axis and fast converging sums/integrals are obtained. We investigate numerically a number of profiles of the background. In each case the vacuum energy turns out to be positive increasing in this way the complete energy and making the vortex configuration less stable. In this problem bound states (tachyonic modes) are present for all investigated profiles making them intrinsically unstable.Comment: 28 pages, 4 figure

Simulated 50 % radiation dose reduction in coronary CT angiography using adaptive iterative dose reduction in three-dimensions (AIDR3D)

To compare the image quality of coronary CT angiography (CTA) studies between standard filtered back projection (FBP) and adaptive iterative dose reduction in three-dimensions (AIDR3D) reconstruction using CT noise additional software to simulate reduced radiation exposure. Images from 93 consecutive clinical coronary CTA studies were processed utilizing standard FBP, FBP with 50 % simulated dose reduction (FBP50 %), and AIDR3D with simulated 50 % dose reduction (AIDR50 %). Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured within 5 regions-of-interest, and image quality for each reconstruction strategy was assessed by two independent readers using a 4-point scale. Compared to FBP, the SNR measured from the AIDR50 % images was similar or higher (airway: 38.3 ± 12.7 vs. 38.5 ± 14.5, p = 0.81, fat: 5.5 ± 1.9 vs. 5.4 ± 2.0, p = 0.20, muscle: 3.2 ± 1.2 vs. 3.1 ± 1.3, p = 0.38, aorta: 22.6 ± 9.4 vs. 20.2 ± 9.7, p < 0.0001, liver: 2.7 ± 1.0 vs. 2.3 ± 1.1, p < 0.0001), while the SNR of the FBP50 % images were all lower (p values < 0.0001). The CNR measured from AIDR50 % images was also higher than that from the FBP images for the aorta relative to muscle (20.5 ± 9.0 vs. 18.3 ± 9.2, p < 0.0001). The interobserver agreement in the image quality score was excellent (κ = 0.82). The quality score was significantly higher for the AIDR50 % images compared to the FBP images (3.6 ± 0.6 vs. 3.3 ± 0.7, p = 0.004). Simulated radiation dose reduction applied to clinical coronary CTA images suggests that a 50 % reduction in radiation dose can be achieved with adaptive iterative dose reduction software with image quality that is at least comparable to images acquired at standard radiation exposure and reconstructed with filtered back projection

Multicenter evaluation of computer automated versus traditional surveillance of hospital-acquired bloodstream infections

Objective.Central line–associated bloodstream infection (BSI) rates are a key quality metric for comparing hospital quality and safety. Traditional BSI surveillance may be limited by interrater variability. We assessed whether a computer-automated method of central line–associated BSI detection can improve the validity of surveillance.Design.Retrospective cohort study.Setting.Eight medical and surgical intensive care units (ICUs) in 4 academic medical centers.Methods.Traditional surveillance (by hospital staff) and computer algorithm surveillance were each compared against a retrospective audit review using a random sample of blood culture episodes during the period 2004–2007 from which an organism was recovered. Episode-level agreement with audit review was measured with κ statistics, and differences were assessed using the test of equal κ coefficients. Linear regression was used to assess the relationship between surveillance performance (κ) and surveillance-reported BSI rates (BSIs per 1,000 central line–days).Results.We evaluated 664 blood culture episodes. Agreement with audit review was significantly lower for traditional surveillance (κ [95% confidence interval (CI)] = 0.44 [0.37–0.51]) than computer algorithm surveillance (κ [95% CI] [0.52–0.64]; P = .001). Agreement between traditional surveillance and audit review was heterogeneous across ICUs (P = .001); furthermore, traditional surveillance performed worse among ICUs reporting lower (better) BSI rates (P = .001). In contrast, computer algorithm performance was consistent across ICUs and across the range of computer-reported central line–associated BSI rates.Conclusions.Compared with traditional surveillance of bloodstream infections, computer automated surveillance improves accuracy and reliability, making interfacility performance comparisons more valid.Infect Control Hosp Epidemiol 2014;35(12):1483–1490</jats:sec