Comparison of Protective Effects of Melatonin and Amifostine on Radiation-Induced Renal Oxidative Stress in Rats

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΗΨΗIn this study, we aimed to compare the protective effects of melatonin and amifostine on radiation-induced oxidative stress. Fifty female Wistar rats (3-4 months old, weighing 200±25 g) were divided into five groups (with ten rats each) and treated as follows: control (Cont), radiotherapy alone (RT), radiotherapy + amifostine (RT+AMI), radiotherapy + melatonin (RT+MEL), radiotherapy + amifostine + melatonin (RT+AMI+MEL). Rats were irradiated individually with a single dose of 8 Gy and amifostine (200 mg/kg) and melatonin (10 mg/kg) was administered to rats 30 minutes before irradiation. At the end of this follow-up period (72 hours) the rats were sacrificed. Spectrophotometric Analysis has been performed to kidney tissue samples. As a result of statistical comparison between groups after RT, total antioxidant capacity (TAC) decreased, total oxidant status (TOS) and oxidative stress index (OSI) increased, although the statistically significant change was only for OSI (p = 0.030). Addition of AMI or MEL to RT increased TAC and OSI significantly (p = 0.000), but there was no additive effect for TAC and OSI when both drugs were given together (p = 1.000, p = 0.172, respectively). In terms of TOS, statistically significant increasing was only for AMI (p = 0.000). There was protective effect when both drugs were given together against on Radiation-Induced Renal Oxidative Stress

Investigation of the structural and electronic properties of CdS under high pressure: an ab initio study

WOS: 000424040400012An ab initio constant pressure study is carried out to explore the behaviour of cadmium sulfide (CdS) under high hydrostatic pressure. We have studied the structural properties of CdS using density functional theory (DFT) under pressure up to 200 GPa. CdS crystallizes in a wurtzite (WZ)-type structure under ambient conditions. CdS undergoes a structural phase transition from the hexagonal WZ-type structure with space group P63mc to cubic NaCl-type structure with space group Fmm. Another phase transition is obtained from NaCl-type structure to the orthorhombic CdS-III-type structure with space group Pmmn. The first transformation proceeds via seven intermediate states with space group Cmc2(1), P2(1), Pmn2(1), P2(1)/m, Pmmn, I4/mmm, and Cmcm. The latter transformation is based on two intermediate states with space groups Immm and P2(1)/m. These phase transitions are also studied by total energy and enthalpy calculations. According to these calculations, the phase transformations occur at about 3 and 51 GPa, respectively. Calculation results on the other basic properties, such as lattice constant, volume, and bulk modulus are also compared with those of other recent theoretical and experimental data, and generally, good agreement with the available data are obtained

The Finite-Size Scaling Study of Five-Dimensional Ising Model

WOS: 000379821800005The five-dimensional ferromagnetic Ising model is simulated on the Creutz cellular automaton algorithm using finite-size lattices with linear dimension 4 <= L <= 8. The critical temperature value of infinite lattice is found to be T-chi(infinity) = 8.7811 (1) using 4 <= L <= 8 which is also in very good agreement with the precise result. The value of the field critical exponent (delta = 3.0067 (2)) is good agreement with delta = 3 which is obtained from scaling law of Widom. The exponents in the finite-size scaling relations for the magnetic susceptibility and the order parameter at the infinite-lattice critical temperature are computed to be 2.5080 (1), 2.5005 (3) and 1.2501 (1) using 4 <= L <= 8, respectively, which are in very good agreement with the theoretical predictions of 5/2 and 5/4. The finite-size scaling plots of magnetic susceptibility and the order parameter verify the finite-size scaling relations about the infinitelattice temperature

Investigation of the structural and electronic properties of CdS under high pressure: an ab initio study

An ab initio constant pressure study is carried out to explore the behaviour of cadmium sulfide (CdS) under high hydrostatic pressure. We have studied the structural properties of CdS using density functional theory (DFT) under pressure up to 200 GPa. CdS crystallizes in a wurtzite (WZ)-type structure under ambient conditions. CdS undergoes a structural phase transition from the hexagonal WZ-type structure with space group P63mc to cubic NaCl-type structure with space group Fmm. Another phase transition is obtained from NaCl-type structure to the orthorhombic CdS-III-type structure with space group Pmmn. The first transformation proceeds via seven intermediate states with space group Cmc2(1), P2(1), Pmn2(1), P2(1)/m, Pmmn, I4/mmm, and Cmcm. The latter transformation is based on two intermediate states with space groups Immm and P2(1)/m. These phase transitions are also studied by total energy and enthalpy calculations. According to these calculations, the phase transformations occur at about 3 and 51 GPa, respectively. Calculation results on the other basic properties, such as lattice constant, volume, and bulk modulus are also compared with those of other recent theoretical and experimental data, and generally, good agreement with the available data are obtained

The Finite-Size Scaling Study of Five-Dimensional Ising Model

The five-dimensional ferromagnetic Ising model is simulated on the Creutz cellular automaton algorithm using finite-size lattices with linear dimension 4 <= L <= 8. The critical temperature value of infinite lattice is found to be T-chi(infinity) = 8.7811 (1) using 4 <= L <= 8 which is also in very good agreement with the precise result. The value of the field critical exponent (delta = 3.0067 (2)) is good agreement with delta = 3 which is obtained from scaling law of Widom. The exponents in the finite-size scaling relations for the magnetic susceptibility and the order parameter at the infinite-lattice critical temperature are computed to be 2.5080 (1), 2.5005 (3) and 1.2501 (1) using 4 <= L <= 8, respectively, which are in very good agreement with the theoretical predictions of 5/2 and 5/4. The finite-size scaling plots of magnetic susceptibility and the order parameter verify the finite-size scaling relations about the infinitelattice temperature

Vitamin-K1 (Phylloquinone) prevents sodium-fluoride (NaF)-induced skeletal fluorosis.

WOS: 000202893600097

Temporomandibular disorders in patients with rheumatoid arthritis: A clinical study

Objectives: The aim of this study is to evaluate the prevalence and type of temporomandibular disorders (TMD) in patients with rheumatoid arthritis (RA).Materials and Methods: Fifty‑four patients having RA treatment at Cukurova University in Rheumatology Clinic were enrolled to the study. Demographic and rheumatologic data were recorded. The patients were examined in Dental Faculty by using Research Diagnostic Criteria/TMD (RDC/TMD) axis I and answered RDC/TMD axis II Biobehavioral Questionnaire. Data were evaluated according instructions for scoring and assessment of RDC/TMD. Mann–Whitney test was performed to compare continuous variables between two groups and Kruskal–Wallis test was performed to compare continuous variables for more than two groups.Results: Although their activity situations were 55.6% active and 44.4% inactive, the distribution of treatment modality was 31.5% for anti‑tumor necrosis factor‑α (TNF‑α) and 68.5% for disease‑modifying antirheumatic drugs (DMARD). The distribution of temporomandibular joint (TMJ) involvement was; 9.3% with no involvement, 7.4% with joint involvement, 64.8% with muscular involvement, 18.5% with both muscular and joint involvement. Rheumatologic functional scores were (0) 3.7%, (1) 50%, (2) 38.9%, (3) 7.4%. Patients’ chronic pain was graded from 0 to 4 and the distribution was 3.7%, 24.1%, 20.4%, 31.5% and 20.4%, respectively. The mean duration of RA for anti‑TNF‑α (11.47 ± 7.67) was significantly higher compared with DMARD (7.09 ± 5.21) P = 0.040.Conclusion: There was a high prevalence of TMD in RA patients, and muscular involvement was the highest among the TMJ involvements. Thus, this study supports TMJ examination should be encouraged in the rheumatology settings.Keywords: Research Diagnostic Criteria, rheumatoid arthritis, rheumatologic functional score, temporomandibular joints, temporomandibular disorder

Temporomandibular disorders in patients with rheumatoid arthritis: A clinical study

PubMedID: 27811440Objectives: The aim of this study is to evaluate the prevalence and type of temporomandibular disorders (TMD) in patients with rheumatoid arthritis (RA). Materials and Methods: Fifty-four patients having RA treatment at Cukurova University in Rheumatology Clinic were enrolled to the study. Demographic and rheumatologic data were recorded. The patients were examined in Dental Faculty by using Research Diagnostic Criteria/TMD (RDC/TMD) axis I and answered RDC/TMD axis II Biobehavioral Questionnaire. Data were evaluated according instructions for scoring and assessment of RDC/TMD. Mann-Whitney test was performed to compare continuous variables between two groups and Kruskal-Wallis test was performed to compare continuous variables for more than two groups. Results: Although their activity situations were 55.6% active and 44.4% inactive, the distribution of treatment modality was 31.5% for anti-tumor necrosis factor-? (TNF-?) and 68.5% for disease-modifying antirheumatic drugs (DMARD). The distribution of temporomandibular joint (TMJ) involvement was; 9.3% with no involvement, 7.4% with joint involvement, 64.8% with muscular involvement, 18.5% with both muscular and joint involvement. Rheumatologic functional scores were (0) 3.7%, (1) 50%, (2) 38.9%, (3) 7.4%. Patients' chronic pain was graded from 0 to 4 and the distribution was 3.7%, 24.1%, 20.4%, 31.5% and 20.4%, respectively. The mean duration of RA for anti-TNF-? (11.47 ± 7.67) was significantly higher compared with DMARD (7.09 ± 5.21) P = 0.040. Conclusion: There was a high prevalence of TMD in RA patients, and muscular involvement was the highest among the TMJ involvements. Thus, this study supports TMJ examination should be encouraged in the rheumatology settings. © 2016 Nigerian Journal of Clinical Practice | Published by Wolters Kluwer - Medknow