183 research outputs found

    Mulching on family maize farms in the tropics: A systematic review

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    Family farms, predominantly reliant on family labour, produce approximately three-quarters of the World's food. Maize (Zea mays) is the world's most produced cereal. Yet in much of the tropics, actual maize yields are far below those attainable with best-bet practices. While any advantage of adding mulch might depend on soil fertility level, mulch quality, amount of rainfall, irrigation, and other factors, no ranking of their importance has been found. Our objectives were to disentangle these influences to assess how mulch affects yields on different fertility soils under different precipitation regimes. We conducted a systematic review in Web of Science, obtaining 50 papers on experiments from the tropics. Fewer trials have been conducted in Asia and Pacific (n = 10) than in Africa (n = 20) or Latin America and the Caribbean (n = 20). Twenty mulches had been tested of which Leucaena leucocephala had been used in 25% of trials. Mulch was more commonly applied after (n = 15) than before (n = 18) sowing or at sowing (n = 14); three trials did not mention application timing. Mulch increased grain yield and biomass. The positive effect of mulch was greater when combined with mineral fertilizer, implying a synergistic rather than a substitutional effect and demonstrating its applicability, even for farmers able to afford inputs. Mulch increased both maize grain yield and total biomass so is recommended as a sustainable practice in general, but particularly on low fertility soils in lower rainfall areas. Future work should model mass loss and nutrient release of different mulch types under different agroecological conditions

    Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents

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    Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes. Viral cell-cell transmission has been shown to play an important role in viral persistence allowing evasion from neutralizing antibodies. In contrast, the role of HCV cell-cell transmission for antiviral resistance is unknown. Aiming to address this question we investigated the phenotype of HCV strains exhibiting resistance to direct-acting antivirals (DAAs) in state-of-the-art model systems for cell-cell transmission and spread. Using HCV genotype 2 as a model virus, we show that cell-cell transmission is the main route of viral spread of DAA-resistant HCV. Cell-cell transmission of DAA-resistant viruses results in viral persistence and thus hampers viral eradication. We also show that blocking cell-cell transmission using host-targeting entry inhibitors (HTEIs) was highly effective in inhibiting viral dissemination of resistant genotype 2 viruses. Combining HTEIs with DAAs prevented antiviral resistance and led to rapid elimination of the virus in cell culture model. In conclusion, our work provides evidence that cell-cell transmission plays an important role in dissemination and maintenance of resistant variants in cell culture models. Blocking virus cell-cell transmission prevents emergence of drug resistance in persistent viral infection including resistance to HCV DAAs

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of ttt\overline{t}, W+bbW+b\overline{b} and W+ccW+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays WνW\rightarrow\ell\nu, where \ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Ahora / Ara

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    La cinquena edició del microrelatari per l’eradicació de la violència contra les dones de l’Institut Universitari d’Estudis Feministes i de Gènere «Purificación Escribano» de la Universitat Jaume I vol ser una declaració d’esperança. Aquest és el moment en el qual les dones (i els homes) hem de fer un pas endavant i eliminar la violència sistèmica contra les dones. Ara és el moment de denunciar el masclisme i els micromasclismes començant a construir una societat més igualitària. Cadascun dels relats del llibre és una denúncia i una declaració que ens encamina cap a un món millor

    Measurement of CP violation parameters and polarisation fractions in Bs0J/ψK0 {\mathrm{B}}_{\mathrm{s}}^0\to \mathrm{J}/\psi {\overline{\mathrm{K}}}^{\ast 0} decays

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    The first measurement of C ⁣P{C\!P} asymmetries in the decay Bs0J/ψK(892)0{B_s^0\to J/\psi \overline{K}^{*}(892)^{0}} and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0fb13.0\,fb^{-1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 77 and 8TeV8\,\mathrm{TeV}. Together with constraints from B0J/ψρ0{B^0\to J/\psi \rho^0}, the results are used to constrain additional contributions due to penguin diagrams in the C ⁣P{C\!P}-violating phase ϕs{{\phi}_{s}}, measured through Bs0{B_s^0} decays to charmonium.The first measurement of CP asymmetries in the decay Bs0J/ψK(892)0 {B}_s^0\to J/\psi {\overline{\mathrm{K}}}^{\ast }{(892)}^0 and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0 fb^{−}^{1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Together with constraints from B0^{0} → J/ψ ρ0^{0}, the results are used to constrain additional contributions due to penguin diagrams in the CP -violating phase ϕs_{s} , measured through Bs0_{s}^{0} decays to charmonium.The first measurement of C ⁣P{C\!P} asymmetries in the decay Bs0J/ψK(892)0{B_s^0\to J/\psi \overline{K}^{*}(892)^{0}} and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0fb13.0\,fb^{-1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 77 and 8TeV8\,\mathrm{TeV}. Together with constraints from B0J/ψρ0{B^0\to J/\psi \rho^0}, the results are used to constrain additional contributions due to penguin diagrams in the C ⁣P{C\!P}-violating phase ϕs{{\phi}_{s}}, measured through Bs0{B_s^0} decays to charmonium

    Measurement of the J/ψ pair production cross-section in pp collisions at s=13 \sqrt{s}=13 TeV

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    The production cross-section of J/ψ pairs is measured using a data sample of pp collisions collected by the LHCb experiment at a centre-of-mass energy of s=13 \sqrt{s}=13 TeV, corresponding to an integrated luminosity of 279 ±11 pb1^{−1}. The measurement is performed for J/ψ mesons with a transverse momentum of less than 10 GeV/c in the rapidity range 2.0 < y < 4.5. The production cross-section is measured to be 15.2 ± 1.0 ± 0.9 nb. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/ψ pair are measured and compared to theoretical predictions.The production cross-section of J/ψJ/\psi pairs is measured using a data sample of pppp collisions collected by the LHCb experiment at a centre-of-mass energy of s=13TeV\sqrt{s} = 13 \,{\mathrm{TeV}}, corresponding to an integrated luminosity of 279±11pb1279 \pm 11 \,{\mathrm{pb^{-1}}}. The measurement is performed for J/ψJ/\psi mesons with a transverse momentum of less than 10GeV/c10 \,{\mathrm{GeV}}/c in the rapidity range 2.0<y<4.52.0<y<4.5. The production cross-section is measured to be 15.2±1.0±0.9nb15.2 \pm 1.0 \pm 0.9 \,{\mathrm{nb}}. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/ψJ/\psi pair are measured and compared to theoretical predictions

    Measurement of forward WeνW\to e\nu production in pppp collisions at s=8\sqrt{s}=8\,TeV

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    A measurement of the cross-section for WeνW \to e\nu production in pppp collisions is presented using data corresponding to an integrated luminosity of 22\,fb1^{-1} collected by the LHCb experiment at a centre-of-mass energy of s=8\sqrt{s}=8\,TeV. The electrons are required to have more than 2020\,GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive WW production cross-sections, where the WW decays to eνe\nu, are measured to be \begin{align*} \begin{split} \sigma_{W^{+} \to e^{+}\nu_{e}}&=1124.4\pm 2.1\pm 21.5\pm 11.2\pm 13.0\,\mathrm{pb},\\ \sigma_{W^{-} \to e^{-}\bar{\nu}_{e}}&=\,\,\,809.0\pm 1.9\pm 18.1\pm\,\,\,7.0\pm \phantom{0}9.4\,\mathrm{pb}, \end{split} \end{align*} where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination. Differential cross-sections as a function of the electron pseudorapidity are measured. The W+/WW^{+}/W^{-} cross-section ratio and production charge asymmetry are also reported. Results are compared with theoretical predictions at next-to-next-to-leading order in perturbative quantum chromodynamics. Finally, in a precise test of lepton universality, the ratio of WW boson branching fractions is determined to be \begin{align*} \begin{split} \mathcal{B}(W \to e\nu)/\mathcal{B}(W \to \mu\nu)=1.020\pm 0.002\pm 0.019, \end{split} \end{align*} where the first uncertainty is statistical and the second is systematic.A measurement of the cross-section for WeνW \to e\nu production in pppp collisions is presented using data corresponding to an integrated luminosity of 22\,fb1^{-1} collected by the LHCb experiment at a centre-of-mass energy of s=8\sqrt{s}=8\,TeV. The electrons are required to have more than 2020\,GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive WW production cross-sections, where the WW decays to eνe\nu, are measured to be \begin{equation*} \sigma_{W^{+} \to e^{+}\nu_{e}}=1124.4\pm 2.1\pm 21.5\pm 11.2\pm 13.0\,\mathrm{pb}, \end{equation*} \begin{equation*} \sigma_{W^{-} \to e^{-}\bar{\nu}_{e}}=\,\,\,809.0\pm 1.9\pm 18.1\pm\,\,\,7.0\pm \phantom{0}9.4\,\mathrm{pb}, \end{equation*} where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination. Differential cross-sections as a function of the electron pseudorapidity are measured. The W+/WW^{+}/W^{-} cross-section ratio and production charge asymmetry are also reported. Results are compared with theoretical predictions at next-to-next-to-leading order in perturbative quantum chromodynamics. Finally, in a precise test of lepton universality, the ratio of WW boson branching fractions is determined to be \begin{equation*} \mathcal{B}(W \to e\nu)/\mathcal{B}(W \to \mu\nu)=1.020\pm 0.002\pm 0.019, \end{equation*} where the first uncertainty is statistical and the second is systematic.A measurement of the cross-section for W → eν production in pp collisions is presented using data corresponding to an integrated luminosity of 2 fb1^{−1} collected by the LHCb experiment at a centre-of-mass energy of s=8 \sqrt{s}=8 TeV. The electrons are required to have more than 20 GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive W production cross-sections, where the W decays to eν, are measured to be σW+e+νe=1124.4±2.1±21.5±11.2±13.0pb, {\sigma}_{W^{+}\to {e}^{+}{\nu}_e}=1124.4\pm 2.1\pm 21.5\pm 11.2\pm 13.0\kern0.5em \mathrm{p}\mathrm{b}, σWeνe=809.0±1.9±18.1±7.0±9.4pb, {\sigma}_{W^{-}\to {e}^{-}{\overline{\nu}}_e}=809.0\pm 1.9\pm 18.1\pm \kern0.5em 7.0\pm \kern0.5em 9.4\,\mathrm{p}\mathrm{b}, where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination

    Measurement of the B0s→μ+μ− Branching Fraction and Effective Lifetime and Search for B0→μ+μ− Decays

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    A search for the rare decays Bs0→μ+μ- and B0→μ+μ- is performed at the LHCb experiment using data collected in pp collisions corresponding to a total integrated luminosity of 4.4  fb-1. An excess of Bs0→μ+μ- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0→μ+μ-)=(3.0±0.6-0.2+0.3)×10-9, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0→μ+μ- effective lifetime, τ(Bs0→μ+μ-)=2.04±0.44±0.05  ps, is reported. No significant excess of B0→μ+μ- decays is found, and a 95% confidence level upper limit, B(B0→μ+μ-)<3.4×10-10, is determined. All results are in agreement with the standard model expectations.A search for the rare decays Bs0μ+μB^0_s\to\mu^+\mu^- and B0μ+μB^0\to\mu^+\mu^- is performed at the LHCb experiment using data collected in pppp collisions corresponding to a total integrated luminosity of 4.4 fb1^{-1}. An excess of Bs0μ+μB^0_s\to\mu^+\mu^- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0μ+μ)=(3.0±0.60.2+0.3)×109{\cal B}(B^0_s\to\mu^+\mu^-)=\left(3.0\pm 0.6^{+0.3}_{-0.2}\right)\times 10^{-9}, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0μ+μB^0_s\to\mu^+\mu^- effective lifetime, τ(Bs0μ+μ)=2.04±0.44±0.05\tau(B^0_s\to\mu^+\mu^-)=2.04\pm 0.44\pm 0.05 ps, is reported. No significant excess of B0μ+μB^0\to\mu^+\mu^- decays is found and a 95 % confidence level upper limit, B(B0μ+μ)<3.4×1010{\cal B}(B^0\to\mu^+\mu^-)<3.4\times 10^{-10}, is determined. All results are in agreement with the Standard Model expectations

    Measurements of prompt charm production cross-sections in pp collisions at s=5 \sqrt{s}=5 TeV

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    Production cross-sections of prompt charm mesons are measured using data from pppp collisions at the LHC at a centre-of-mass energy of 55\,TeV. The data sample corresponds to an integrated luminosity of 8.60±0.338.60\pm0.33\,pb1^{-1} collected by the LHCb experiment. The production cross-sections of D0D^0, D+D^+, Ds+D_s^+, and D+D^{*+} mesons are measured in bins of charm meson transverse momentum, pTp_{\text{T}}, and rapidity, yy. They cover the rapidity range 2.0<y<4.52.0 < y < 4.5 and transverse momentum ranges 0<pT<10GeV/c0 < p_{\text{T}} < 10\, \text{GeV}/c for D0D^0 and D+D^+ and 1<pT<10GeV/c1 < p_{\text{T}} < 10\, \text{GeV}/c for Ds+D_s^+ and D+D^{*+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1<pT<8GeV/c1 < p_{\text{T}} < 8\, \text{GeV}/c are determined to be \begin{equation*} \sigma(pp\rightarrow D^0 X) = 1190 \pm 3 \pm 64\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^+ X) = 456 \pm 3 \pm 34\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D_s^+ X) = 195 \pm 4 \pm 19\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^{*+} X)= 467 \pm 6 \pm 40\,\mu\text{b} \end{equation*} where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from pp collisions at the LHC at a centre-of-mass energy of 5 TeV. The data sample corresponds to an integrated luminosity of 8.60 ± 0.33 pb1^{−1} collected by the LHCb experiment. The production cross-sections of D0^{0}, D+^{+}, Ds+_{s}^{+} , and D+^{∗+} mesons are measured in bins of charm meson transverse momentum, pT_{T}, and rapidity, y. They cover the rapidity range 2.0 < y < 4.5 and transverse momentum ranges 0 < pT_{T} < 10 GeV/c for D0^{0} and D+^{+} and 1 < pT_{T} < 10 GeV/c for Ds+_{s}^{+} and D+^{∗+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1 < pT_{T} < 8 GeV/c are determined to be σ(ppD0X)=1004±3±54μb,σ(ppD+X)=402±2±30μb,σ(ppDs+X)=170±4±16μb,σ(ppD+X)=421±5±36μb, \begin{array}{l}\sigma \left( pp\to {D}^0X\right)=1004\pm 3\pm 54\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{+}X\right)=402\pm 2\pm 30\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}_s^{+}X\right)=170\pm 4\pm 16\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{\ast +}X\right)=421\pm 5\pm 36\mu \mathrm{b},\end{array} where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from pppp collisions at the LHC at a centre-of-mass energy of 55\,TeV. The data sample corresponds to an integrated luminosity of 8.60±0.338.60\pm0.33\,pb1^{-1} collected by the LHCb experiment. The production cross-sections of D0D^0, D+D^+, Ds+D_s^+, and D+D^{*+} mesons are measured in bins of charm meson transverse momentum, pTp_{\text{T}}, and rapidity, yy. They cover the rapidity range 2.0<y<4.52.0<y<4.5 and transverse momentum ranges 0<pT<10GeV/c0 < p_{\text{T}} < 10\, \text{GeV}/c for D0D^0 and D+D^+ and 1<pT<10GeV/c1 < p_{\text{T}} < 10\, \text{GeV}/c for Ds+D_s^+ and D+D^{*+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1<pT<8GeV/c1 < p_{\text{T}} < 8\, \text{GeV}/c are determined to be \sigma(pp\rightarrow D^0 X) = 1004 \pm 3 \pm 54\,\mu\text{b} \sigma(pp\rightarrow D^+ X) = 402 \pm 2 \pm 30\,\mu\text{b} \sigma(pp\rightarrow D_s^+ X) = 170 \pm 4 \pm 16\,\mu\text{b} \sigma(pp\rightarrow D^{*+} X)= 421 \pm 5 \pm 36\,\mu\text{b} where the uncertainties are statistical and systematic, respectively

    Does Mulching Increase Maize Yields in the Tropics? A Systematic Review

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    Maize is one of the most important staples in the Tropics. The use of mulch in maize cropping is widespread and a plethora of trials have been conducted since the 1980s. Yet few studies have attempted to synthesise data to identify general patterns and research gaps. We hypothesised that mulching increases grain yield, depending on rainfall, the growing period of the maize, timing of mulch application, and that also applying mineral fertiliser might be synergistic. We conducted a systematic review in web of science. Inclusion criteria included that trials were monocultures, had a non-mulch control and were from the tropics. We found 54 papers fulfiling our criteria and from these we extracted grain yield data, as the proportion between relative grain yield and control, arcsine square root transformed them and analysed them in R v. 3.6.1. The most commonly tested mulch was Leucaena leucocephala (n = 13). Treatments often involved additional factors, for example tillage, irrigation and fertiliser, whereas mulching was the only factor in 15 papers. Mulching improved maize grain yield (+ 30 %), yet the % increase was significantly higher in areas where precipitation > 1500 mm p.a. (+ 48 %) than where precipitation < 800 mm p.a. (9 %). Where mulch was applied after sowing, the highest % increase was obtained (+ 44 %), compared with mulch applied at (+ 29 %) or before sowing (+ 18 %). The shorter the maize growing season, the more pronounced the improvement with mulching. Where combined with mineral fertiliser, the improvement was accentuated, suggesting synergies from combining different inputs. Using fresh rather than dry material resulted in a greater % yield increase. Improvement with mulching over the control was greater in long-term trials compared to short-term trials. In conclusion, mulching increased grain yield, particularly for short season maize, optimally applied post-sowing, and showed synergisms with, rather than replacing fertiliser. Surprisingly, effects were most pronounced in higher rainfall areas, suggesting a role as a nutrient input rather than just a soil water conserving strategy
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