EFFECT OF LOWER ETHANOL GASOLINE BLENDS ON PERFORMANCE AND EMISSION CHARACTERISTICS OF THE SINGLE CYLINDER SI ENGINE

Alcohols, basically ethanol is considered as a leading alternative fuel for automotive application because of its ability to reduce the air pollution and cost of the fuel. This paper investigates the effect of lower ethanol gasoline blends (up to 20% by volume) on performance and emission characteristics of the single cylinder four stroke SI engine. Tests were carried out for power, torque, fuel consumption and brake mean effective pressure, while exhaust emissions were analyzed for CO, CO2, and HC by using different ethanol gasoline blends on volume basis at wide open throttle and variable engine speed from 4000 to 8000 rpm. Results were compared with the pure gasoline. It showed that as the ethanol content increases the power, torque, fuel consumption, brake mean effective pressure and CO2 emission while reduces HC and CO emission

Holistic Slowdown Driven Scheduling and Resource Management for Malleable Jobs

In job scheduling, the concept of malleability has been explored since many years ago. Research shows that malleability improves system performance, but its utilization in HPC never became widespread. The causes are the difficulty in developing malleable applications, and the lack of support and integration of the different layers of the HPC software stack. However, in the last years, malleability in job scheduling is becoming more critical because of the increasing complexity of hardware and workloads. In this context, using nodes in an exclusive mode is not always the most efficient solution as in traditional HPC jobs, where applications were highly tuned for static allocations, but offering zero flexibility to dynamic executions. This paper proposes a new holistic, dynamic job scheduling policy, Slowdown Driven (SD-Policy), which exploits the malleability of applications as the key technology to reduce the average slowdown and response time of jobs. SD-Policy is based on backfill and node sharing. It applies malleability to running jobs to make room for jobs that will run with a reduced set of resources, only when the estimated slowdown improves over the static approach. We implemented SD-Policy in SLURM and evaluated it in a real production environment, and with a simulator using workloads of up to 198K jobs. Results show better resource utilization with the reduction of makespan, response time, slowdown, and energy consumption, up to respectively 7%, 50%, 70%, and 6%, for the evaluated workloads

DROM: Enabling Efficient and Effortless Malleability for Resource Managers

In the design of future HPC systems, research in resource management is showing an increasing interest in a more dynamic control of the available resources. It has been proven that enabling the jobs to change the number of computing resources at run time, i.e. their malleability, can significantly improve HPC system performance. However, job schedulers and applications typically do not support malleability due to the common belief that it introduces additional programming complexity and performance impact. This paper presents DROM, an interface that provides efficient malleability with no effort for program developers. The running application is enabled to adapt the number of threads to the number of assigned computing resources in a completely transparent way to the user through the integration of DROM with standard programming models, such as OpenMP/OmpSs, and MPI. We designed the APIs to be easily used by any programming model, application and job scheduler or resource manager. Our experimental results from two realistic use cases analysis, based on malleability by reducing the number of cores a job is using per node and jobs co-allocation, show the potential of DROM for improving the performance of HPC systems. In particular, the workload of two MPI+OpenMP neuro-simulators are tested, reporting improvement in system metrics, such as total run time and average response time, up to 8% and 48%, respectively.This work is partially supported by the Span- ish Government through Programa Severo Ochoa (SEV-2015-0493), by the Spanish Ministry of Science and Technology through TIN2015-65316-P project, by the Generalitat de Catalunya (contract 2017-SGR-1414) and from the European Union’s Horizon 2020 under grant agreement No 785907 (HBP SGA2)Peer ReviewedPostprint (author's final draft

Use of anti-snake venom and clinical outcomes in snake envenomation: a prospective observational study

Background: The only effective measure to prevent or reverse most of the manifestations of venomous snake-bite is timely administration of antisnake venom (ASV) with or without adjunctive treatment as necessary in each case. But recently several concerns have been raised with regard to use of polyvalent ASV. Hence the present study was conducted to assess use of ASV, early adverse reactions to ASV, adjunctive treatment and clinical outcomes in snake-bite patients, which would help to identify areas of problem and provide basis for planning strategies to increase rational use of drugs.Methods: It was a prospective observational study approved by Institutional Ethics Committee. All indoor patients with systemic manifestations of snake envenomation were included in the study. All participants gave written informed consent. Data was obtained prospectively using a structured case record form. Descriptive statistics was used to express the results.Results: Among 52 patients, snake-bite predominantly affected males (59.62%) than females (40.38%). The most common site of snake-bite was lower limb (65.38%). The main indication for ASV administration was vasculotoxic snake-bite (59.62%). Mean dose of ASV use was 18.21±15.51 vials. Mortality was seen in one patient. Majority of patients (28/52, 53.85%) received ASV in the range of 1-10 vials for the management of snake-bite.Conclusions: The use and dose of ASV was appropriate in vasculotoxic snake-bite while few neurotoxic snake-bite patients needed higher than recommended dose.

A study of adverse drug reactions in patients receiving treatment for multi-drug resistant tuberculosis

Background: A high frequency of adverse drug reactions (ADRs) is one of the major challenges in the treatment of Multi-drug resistant tuberculosis (MDR-TB). Patients may refuse to continue treatment if ADRs are not properly addressed, drugs may be stopped unnecessarily and treatment may be terminated prematurely by inexperienced health workers, resulting in a high proportion of failure.Methods: Patients diagnosed for MDR-TB and registered in Drug Resistant TB centre (DR-TB) of tertiary care hospital during period of July 2014 to June 2015 were enrolled in the study. Data of patients hospitalized for the complaints of ADR in DR-TB centre during study period was collected.Results: Out of 468 patients, 60 (12.82%) patients developed at least one adverse reaction and were hospitalised for the same. Among 109 reported ADRs, Gastrointestinal upset was the most common ADR reported (5.98%) followed by psychosis (4.91%) and ototoxicity (2.99%).Conclusions: The health providers, the patients and their relatives should be sensitised about these ADRs for early detection and treatment. It can also be suggested that the setup of DR-TB centre should be integrated with psychiatry and ENT specialities, with all the provisions of early detection of ADR and treatment

An assessment of attitudes towards plastics and bioplastics in Europe

Over the last 50 years, conventional fossil-based plastics have become an integral part of our everyday lives. Apart from their low production costs, this is due to a number of their unique properties, including durability, strength, lightness, electrical and thermal insulation, resistance to chemicals and corrosion. The production of plastics has increased from 1.5 million metric tons in 1950 to 359 million metric tons in 2018. Of this total, 61.8 million metric tons were produced in Europe. There are various problems associated with plastic use and disposal that pose a serious threat to both the physical environment and human health. Since public behaviour plays a key role when it comes to the use of plastic, this paper reports on a study that focused on an assessment of attitudes towards plastics and bioplastics in Europe. The results showed that packaging is the most frequent modality of plastic used among participants. In addition, majority of participants are aware that plastic waste can affect environment and human health and therefore segregate and properly dispose plastics. Also, even though most respondents were aware of the environmental problems related to plastic use and showed a positive inclination towards using bioplastic materials, their limited availability and lack of relevant information about bioplastics pose a problem for wider use. Departing from the assumption that the public attitude is a determining factor in the consumption of plastics as a whole and bioplastics in particular, this paper also sheds some light on the current situation, identifying some trends and information gaps which should be addressed in order to encourage a more rational use of plastics in Europe

Analysis and Experimental Validation for Behavior (Compression, Tensile, Fatigue Etc.)of Composite Material Helical Compressive Spring Used for Four Wheeler Suspension System.

The Helical spring is used for suspension in automobile. The Helical spring absorbed the shocks and bump. The present study explores about experimental and computational analysis of helical spring used in automobile. This study concentrated on the use of composite material for manufacturing of helical spring. Overall this study compares the results obtained by experimental analysis of existing mild steel material helical spring by using Universal Testing machine and composite material helical spring. The validation of experimental results is given by ANSYS computational results. Finally the Comparison is done for concluded the results