Antidiabetic and antihyperlipidemic effects of Dillenia indica (L.) leaves extract

The present study was carried out to evaluate antidiabetic and antihyperlipidemic effects of Dillenia indica methanolic leaves extracts in streptozotocin induced diabetic Wistar rats by administering graded oral doses (250 and 500 mg/kg body weight) for 21 days. The extract showed significant antidiabetic activity (pRealizou-se o presente estudo para avaliar os efeitos antidiabético e anti-hiperlipidêmico de extratos metanólicos de folhas de Dillenia indica em ratos wistar com diabetes induzido por estreptozotocina por meio da administração de doses orais (250 e 500 mg/kg de peso corporal) por 21 dias. O extrato mostrou atividade antidiabética significativa (

Effect on Physiological Variables and Urinary Metabolites following a Single Dermal Application of Sulphur Mustard in Rats

The effect of single dermal application of different doses of sulphur mustard (2,2'-dichlorodiethyl sulphide, SM), i.e.5, 10 and 20 mg/kg body weight on some physiological variables, viz., body weight, intake of food and water, and excretion of excreta and urine was studied for one week. Levels of urinary metabolites, uric acid, urea, protein, creatine and creatinine were measured at 0, 1, 2, and 7 days in albino rats of Wister strain. A progressive dose-dependent fall in body weight was observed from day onwards after SM application. Feed and water intake were reduced significantly. Excretion of urine and exdreta was also affected adversely. The level of uric acid, a metabolite of purine bases, increased 24 hr post-exposure, in a time and dose-dependent manner. Excretion of urea decreased and the level of creatine increased drastically on 7th day. However, urinary excretions of protein and creatinine did not change. The study shows that single application of SM in rats induces a catabolic state

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Weed flora dynamics and growth response of green gram (Vigna radiata (L.) R. Wilczek) under varied agri-horti system and weed management practices

Horizontal expansion of pulse production can be achieved by introduction of short duration pulse crop like, green gram (Vigna radiata (L.) R. Wilczek) under agri-horti system. Response of green gram under different agri-horti system and weed management practices is lacking. Therefore, an agronomic trial was conducted during monsoon season of 2011 at Agricultural Research Farm, Rajeev Gandhi South Campus, Banaras Hindu University, Barkachha, Mirzapur, Uttar Pradesh, in split plot design, consisting of three agri-horti systems [guava, custard apple and open field] in main plots and six weed management practices [pendimethalin 1000 g/ha (PE), imazethapyr 125 and 200 g/ha (PoE), 1-HW (20 DAS), 2-HW (15 and 30 DAS) and weedy check] were assigned to sub plots and replicated thrice. Green gram variety ‘Samrat’ was sown as per standard agronomic package of practices on August 5, 2011 in open field as well as within the alleys of, 5-year old, guava and custard apple agri-horti system. Agri-horti systems, did not significantly (P<0.05) affect the growth, yield attributes, yield and nutrient content in green gram. The weed management practices significantly affected the CGR, RGR and yield of green gram. Application of imazethapyr 200 g/ha recorded 79.08% reduction in weed biomass and 11.38% lower seed yield as compared to weedy check and 2-HW (15 and 30 DAS), respectively. 2-hand weeding effectively reduced weed biomass (88.07%) and showed highest yield (888.79 kg/ha), and CGR (13.61 g/day) followed by imazethapyr 200g/ha yield (787.66 kg/ha) and CGR (13.14 g/day)

The Impact of Child Labour: An Analytical Study

Development is touching its peak daily in today's world, but Some issues remain constant. Child labor is the most underrated issue that cannot be controlled easily and increasing without any negotiations. When children are employed in jobs that rob them of their youth, prevent them from attending regular school, or are physically, intellectually, socially, or morally detrimental, this is referred to as child labor. Child labor is a major global issue that affects millions of children and their families. This form of exploitation prevents kids from exercising their right to education, healthy development, and safe childhood. The impact of child labor is far-reaching and can have long-lasting effects on children, their families, and communities. This form of exploitation deprives children of their right to education, healthy development, and safe childhood. The impact of child labor is far-reaching and can have long-lasting effects on children, their families, and communities. Children who are forced to work often experience physical and emotional harm, reduced opportunities for personal and academic development, and reduced future earning potential. Additionally, child labor perpetuates poverty and perpetuates the cycle of exploitation from generation to generation. The international community has made progress in addressing child labor, but much more needs to be done to eliminate this harmful practice and give kids the opportunity and support they need to succeed. The impact of child labor can only be fully addressed through a sustained and coordinated effort from governments, businesses, and civil society organizations despite being illegal in many countries, child labor remains a widespread problem, in particular in developing nations where poverty and a lack of educational opportunities encourage families to send their kids to work. The Impact of child labor includes impaired cognitive and physical development, decreased educational attainment, and perpetuation of the cycle of poverty