73 research outputs found
Influence of charge asymmetry and isospin dependent cross-section on elliptical flow
Using the isospin dependent quantum molecular dynamics model, we study the
effect of charge asymmetry and isospin dependent cross-section on different
aspects of elliptical flow. Simulations have been carried out for the reactions
of , where m = (47, 50, 53, 57 and 59) and
, where n= (14, 16, 18, 21 and 23). Our study shows that
elliptical flow depend strongly on the isospin of cross-section. The transition
energy remains almost constant with increase in N/Z of the system. A good
agreement is obtained with experimental measurements
Effect of isospin dependent cross-section on fragment production in the collision of charge asymmetric nuclei
To understand the role of isospin effects on fragmentation due to the
collisions of charge asymmetric nuclei, we have performed a complete
systematical study using isospin dependent quantum molecular dynamics model.
Here simulations have been carried out for , where n
varies from 47 to 59 and for , where m varies from 14
to 23. Our study shows that isospin dependent cross-section shows its influence
on fragmentation in the collision of neutron rich nuclei
Effects of Six-Week Plyometrics on Vertical Jumping Ability of Volleyball Players
Abstract The study was designed to find the six-week Plyometric
Synthesis and DPPH scavenging assay of reserpine analogues, computational studies and in silico docking studies in AChE and BChE responsible for Alzheimer's disease
A doença de Alzheimer (DA) é uma doença neurodegenerativado sistema nervoso central, em rápido crescimento, e antioxidantes ajudam a suprimir o estresse oxidativo causado por radicais livres, responsávies pela DA. Avaliou-se, biologicamente, série de derivados sintéticos de indol selecionados para identificar novos antioxidantes. A maioria dos compostos avaliados apresentou de significativa a boa propriedade antioxidante (valor de IC50 399,07140.0 ± 50 µM). Eftuaram-se estudos de Teoria do Funcional de Densidade (DFT) com os compostos e os seus correspondentes radicais livres. As diferenças de energia entre os compostos protótipos e os radicais livres correspondentes proporcionaram boa justificativa para a tendência encontrada nos seus valores de IC50. O ancoramento in silico dos compostos com a acetilcolinesterase (AChE) e com a butirilcolinesterase (BChE), que contribuem para a DA, foi, também, realizado para prever o seu potencial anti-DA.Alzheimer's disease (AD) is a fast growing neurodegenerative disorder of the central nervous system and anti-oxidants can be used to help suppress the oxidative stress caused by the free radicals that are responsible for AD. A series of selected synthetic indole derivatives were biologically evaluated to identify potent new antioxidants. Most of the evaluated compounds showed significant to modest antioxidant properties (IC50 value 399.07 140.0±50 µM). Density Functional Theory (DFT) studies were carried out on the compounds and their corresponding free radicals. Differences in the energy of the parent compounds and their corresponding free radicals provided a good justification for the trend found in their IC50 values. In silico, docking of compounds into the proteins acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), which are well known for contributing in AD disease, was also performed to predict anti-AD potential
CHEMICAL PENETRATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY SYSTEM
In present scenario more than 70% of the drugs that are taken by oral route are found to be less effective as desired, to overcome this constraint Transdermal drug delivery system has emerged as an innovative area of research, this system helps in delivering the drugs and macromolecules through skin into systemic circulation. At present, the worldwide market of Transdermal patch has reached 2 billion pounds. Many drugs like Estrogen, Progestrone, Nitroglycerine, Clonodine etc. are fabricated in form of Transdermal patches due to its ability to deliver the drug in non-invasive manner and also to overcome the problems associated with oral route. Although the Transdermal patches deliver the drug at predetermined rate1, the partitioning of drug from the system to the skin and then penetration through different layers of skin can be altered by adding penetration enhancers that can be physical or chemical in nature. This article deals with the role of different chemicals that can be used as penetration enhancer.
Keywords: Penetration enhancer, Layer of skin, Fatty alcohol and glyco
Anisotropic distribution of nucleon participating in elliptical flow
Using the isospin dependent quantum molecular dynamics model, we study the
effect of charge asymmetry and isospin dependent cross-section on
and . Simulations have been
carried out for the reactions of , where m = (47, 50
and 59) and . Our study shows that these parameters
depend strongly on the isospin of cross-section and charge asymmetry. The
distribution of nucleons and fragments is not symmetric around the beam axis
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