204 research outputs found
Ankieta w sprawie rewizji Konstytucji polskiej
Digitalizacja i deponowanie archiwalnych zeszytów RPEiS sfinansowane przez MNiSW w ramach realizacji umowy nr 541/P-DUN/201
360 deg Camera Head for Unmanned Sea Surface Vehicles
The 360 camera head consists of a set of six color cameras arranged in a circular pattern such that their overlapping fields of view give a full 360 view of the immediate surroundings. The cameras are enclosed in a watertight container along with support electronics and a power distribution system. Each camera views the world through a watertight porthole. To prevent overheating or condensation in extreme weather conditions, the watertight container is also equipped with an electrical cooling unit and a pair of internal fans for circulation
Estudios de aprovechamiento integral de cáscara de naranja
En el año 2004 Argentina ha cosechado 736.607 toneladas de naranjas, derivándose el 20 % de la misma a industrialización. La región mesopotámica destinada a la actividad citrícola participó con el 34 % de la producción nacional, y de ella el 45 % fue naranjas. La provincia de Entre Ríos es la principal productora nacional de naranjas con 261.000 toneladas. Si tenemos en cuenta que el 40 - 45 % de la fruta que ingresa a una planta fabril está formada por cáscara y semilla que en la actualidad tiene un mínimo aprovechamiento, tenemos como residuo de la naranja industrializada 25.000 toneladas anuales. Las sustancias pécticas se encuentran en las paredes celulares de los vegetales, entre ellos en la cáscara de naranja donde su contenido es alrededor del 30% (B. S.) y su valor comercial radica en sus propiedades reológicas y contenido en fibra digerible. La actividad experimental concretada para abordar el aprovechamiento integral de la cáscara de naranja permitió evaluar procesos de optimización como inactivación enzimática del mesocarpio (tratamiento durante 30 min con vapor fluente inactiva el 99 % de la actividad), extracción de sólidos solubles (a temperatura ambiente el efecto de difusión de sólidos solubles es más relevante que la solubilización de pectina), deshidratación de la cáscara (la modelización de este proceso permite su optimización) y extracción de pectina (en la cual hay varios factores relevantes como pH del solvente, la relación solvente-sólido, el tiempo de extracción, etc.). La información presentada en este trabajo será relevante para seleccionar el procesamiento posterior de cáscara
mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes
Individuals with primary antibody deficiency (PAD) syndromes have poor humoral immune responses requiring immunoglobulin replacement therapy. We followed individuals with PAD after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination by evaluating their immunoglobulin replacement products and serum for anti-spike binding, Fcγ receptor (FcγR) binding, and neutralizing activities. The immunoglobulin replacement products tested have low anti-spike and receptor-binding domain (RBD) titers and neutralizing activity. In coronavirus disease 2019 (COVID-19)-naive individuals with PAD, anti-spike and RBD titers increase after mRNA vaccination but wane by 90 days. Those vaccinated after SARS-CoV-2 infection develop higher and more sustained responses comparable with healthy donors. Most vaccinated individuals with PAD have serum-neutralizing antibody titers above an estimated correlate of protection against ancestral SARS-CoV-2 and Delta virus but not against Omicron virus, although this is improved by boosting. Thus, some immunoglobulin replacement products likely have limited protective activity, and immunization and boosting of individuals with PAD with mRNA vaccines should confer at least short-term immunity against SARS-CoV-2 variants, including Omicron
SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients
BACKGROUND: Although SARS-CoV-2 vaccines have proven effective in eliciting a protective immune response in healthy individuals, their ability to induce a durable immune response in immunocompromised individuals remains poorly understood. Primary antibody deficiency (PAD) syndromes are among the most common primary immunodeficiency disorders in adults and are characterized by hypogammaglobulinemia and impaired ability to mount robust antibody responses following infection or vaccination.
METHODS: Here, we present an analysis of both the B and T cell response in a prospective cohort of 30 individuals with PAD up to 150 days following initial COVID-19 vaccination and 150 days post mRNA booster vaccination.
RESULTS: After the primary vaccination series, many of the individuals with PAD syndromes mounted SARS-CoV-2 specific memory B and CD4
CONCLUSION: Together, these data indicate that SARS-CoV-2 vaccines elicit memory B and T cells in most PAD patients and highlights the importance of booster vaccination in immunodeficient individuals
Symmetric Jump Processes and their Heat Kernel Estimates
We survey the recent development of the DeGiorgi-Nash-Moser-Aronson type
theory for a class of symmetric jump processes(or equivalently, a class of
symmetric integro-differential operators). We focus on the sharp two-sided
estimates for the transition density functions (or heat kernels) of the
processes, a priori Holder estimate and parabolic Harnack inequalities for
their parabolic functions. In contrast to the second order elliptic
differential operator case, the methods to establish these properties for
symmetric integro-differential operators are mainly probabilistic.Comment: To appear in Science in China Series A: Mathematic
Why Iranian married women use withdrawal instead of oral contraceptives? A qualitative study from Iran
<p>Abstract</p> <p>Background</p> <p>Withdrawal as a method of birth control is still used in Iran. The aim of this study was to explore married women's perspectives and attitudes on withdrawal use instead of oral contraceptive (OC) in Tehran, Iran.</p> <p>Methods</p> <p>This was a qualitative study. Participants were 50 married women, not currently pregnant, not desiring pregnancy and who had been using withdrawal for contraception. Face-to face interviews were conducted to collect data. Content analysis was performed to analyze the data.</p> <p>Results</p> <p>Four major themes were extracted from the interviews: advantages, disadvantages, barriers for OC use, and husband-related factors. Advantages of withdrawal use were identified as: easy to use, convenient, ease of access, natural. Even those participants who had experienced unwanted pregnancy while using withdrawal, relied on withdrawal as their contraceptive method. Disadvantages of OC included concerns about side effects. Barriers related to use of OC included the need for medical advice, vaginal examination and daily use. Husband-related factors included: the husband wanted to be the primary decision maker on the number of children and that he preferred withdrawal.</p> <p>Conclusion</p> <p>Health providers should address misunderstandings that exist about OC and highlight the non-contraceptive health benefits of OC to balance the information provided for women. We suggest that not only women but also their spouses be advised in family planning programs.</p
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