Media publiczne w Polsce a popularyzacja wiedzy o języku polskim

One of the statutory provisions of public media is to popularize the knowledge of the Polish language – the present authors analyse diversified aspects determining the effectiveness of the execution of the task and the media’s commitment to its social responsibility, and proceed to evaluate the basic assignments and responsibilities involved in the journalistic profession. These responsibilities result largely from the reception of the profession by the general public, and from those that emerge within the context of studies on language authority figures in present-day Poland. The next stage of the analysis involves an evaluation of the activities of all-Polish national broadcasters in view of their practical implementation and execution of the commitments set in Art. 21, Section 1a, item 8 of the Radio and Television Act (diffusion and divulgation of the knowledge of the Polish language). The remaining part of the article, including postulative claims, results from an analysis of the activities popularizing the knowledge on Polish available in the media and from the conviction of the necessity of expanding them beyond just grammaticality and correctness in the language use

Cardiac hemangioma of the right atrium in a neonate : fetal management and expedited surgical resection

Cardiac hemangioma is a rare tumor with a reported incidence of 1-2%. We describe the case of a neonate with a right atrial mass that was diagnosed prenatally. The fetus developed a supraventricular tachycardia and was delivered by cesarean section in the 35th week of gestation. The infant underwent surgery after 24 hours to remove the mass which was diagnosed as a cardiac capillary-cavernous hemangioma.peer-reviewe

Mowa niezależna w przekazie medialnym a podstawowe funkcje informacji dziennikarskiej (część 3)

This article is a part of research project that focuses on citations in media coverage in Poland after 1989; two earlier installments of the article have been included in earlier publications of “Poznańskie Studia Polonistyczne”. Part Three provides a discussion on and characteristics of the category of the average man in the street, ordinary people whose utterances are increasingly included in the journalistic narration. Taking the notion of everyday life, with which the demand for an ordinary man in the media is closely linked, as a starting point in the discussion, the authors proceed to characterize citations, along with their explanatory attributions, indicate their textual functions and analyse the categories that are revealed within the process: anonymity, transparency and singularity.1919211Poznańskie Studia Polonistyczne. Seria Językoznawcz

Mowa niezależna w przekazie medialnym a podstawowe funkcje informacji dziennikarskiej (część 3)

This article is a part of research project that focuses on citations in media coverage in Poland after 1989; two earlier installments of the article have been included in earlier publications of “Poznańskie Studia Polonistyczne”. Part Three provides a discussion on and characteristics of the category of the average man in the street, ordinary people whose utterances are increasingly included in the journalistic narration. Taking the notion of everyday life, with which the demand for an ordinary man in the media is closely linked, as a starting point in the discussion, the authors proceed to characterize citations, along with their explanatory attributions, indicate their textual functions and analyse the categories that are revealed within the process: anonymity, transparency and singularity

Anarchizm w „Homku” Ruchu Społeczeństwa Alternatywnego w kontekście mowy wrogości

This text analyses the Homek magazine published by Ruch Społeczeństwa Alternatywnego (RSA) [Alternative Society Movement] – a community of people with neoanarchist views first co-creating the underground Solidarność and later functioning independently. Homek, as an underground newspaper, was initially published bi-weekly, then monthly and later irregularly. This article focuses on, firstly, the RSA community’s position on hostile attitudes (including the so-called hate speech) and, secondly, on the use of the term walka [fight] as what we believe to have been a self-creation device.This text analyses the Homek magazine published by Ruch Społeczeństwa Alternatywnego (RSA) [Alternative Society Movement] – a community of people with neoanarchist views first co-creating the underground Solidarność and later functioning independently. Homek, as an underground newspaper, was initially published bi-weekly, then monthly and later irregularly. This article focuses on, firstly, the RSA community’s position on hostile attitudes (including the so-called hate speech) and, secondly, on the use of the term walka [fight] as what we believe to have been a self-creation device

O języku publikacji Ruchu Społeczeństwa Alternatywnego („Homek” i druki ulotne)

The text has been devoted to the analysis of the publications of the Movement of Alternative Society (Pol. Ruch Społeczeństwa Alternatywnego, RSA), a group gathering people with neo-anarchist views, originally jointly creating underground Solidarity movement, and later operating independently. The adopted research perspective—primarily pragmatic and stylistic—enabled scholars to distinguish and describe several features of the analysed magazines of the second circulation: the magazine Homek (at the beginning published as a biweekly, then as a monthly and finally published erratically) and ephemeral prints constituting an important tool of the Movement’s (RSA) operation

The effects of fiscal autonomy on the size of public sector and the strength of political budget cycles in local expenditure

We analyze the effects of political business cycles and fiscal autonomy on the expenditure categories of Polish municipalities. Using System GMM technique, we find convincing evidence for strong political business cycles in almost all expenditure categories, and in particular for the categories of expenditure relevant for electoral success such as infrastructure and social expenditure. Transfers to municipalities from the central government accentuate the strength of the electoral cycles, but surprisingly are associated with lower expenditure levels outside of the election periods. The latter results are the main finding: fiscal autonomy although not necessarily reducing the levels of local expenditure, does reduce the level of political manipulation of the budgets

Genetic predisposition to papillary thyroid cancer

Około 5% zróżnicowanych raków tarczycy wykazuje predyspozycję dziedziczną. Dziedziczny nierdzeniasty rak tarczycy może występować jako składowa niektórych dziedzicznych zespołów nowotworowych, na przykład rodzinnej polipowatości jelit oraz jako rodzinny zróżnicowany rak tarczycy (FNMTC, familial non-medullary thyroid cancer), gdzie najczęściej obserwuje się raka brodawkowatego. Choć predyspozycja dziedziczna do nierdzeniastych raków tarczycy jest dobrze znana, to jednak geny warunkujące jej występowanie nie zostały jeszcze poznane. Wykonane jak dotąd badania zidentyfikowały kilka loci - 1q21, 6q22, 8p23.1-p22 oraz 8q24, jednak wyniki te nie zawsze były jednoznaczne. W niniejszej pracy omówiono rezultaty badań sprzężenia oraz ostatnio uzyskane wyniki badań związku całego genomu (GWAS, genome wide association study) wykonano przez badania polimorfizmu pojedynczego nukleotydu (SNP, single nucleotide polymorphism) z wykorzystaniem techniki mikromacierzy wysokiej gęstości. (Endokrynol Pol 2010; 61 (5): 486-489)Approximately 5% of differentiated thyroid cancers are hereditary. Hereditary non-medullary thyroid cancer may occur as a minor component of familial cancer syndromes (e.g. familial adenomatous polyposis) or as a primary feature (familial non-medullary thyroid cancer [FNMTC]). Among FNMTC, PTC is the most common. Although a hereditary predisposition to non-medullary thyroid cancer is well established, the susceptibility genes are poorly known. Up to now, by linkage analysis using microsatellite markers, several putative loci have been described - 1q21, 6q22, 8p23.1-p22, and 8q24; however, validation studies have been unsuccessful. In the present review we discuss the results of linkage analysis and the most recent results of genome wide association studies (GWAS) with high resolution SNP (single nucleotide polymorphism) arrays. (Pol J Endocrinol 2010; 61 (5): 486-489

Disorders in the CMG helicase complex increase the proliferative capacity and delay chronological aging of budding yeast

The replication of DNA requires specialized and intricate machinery. This machinery is known as a replisome and is highly evolutionarily conserved, from simple unicellular organisms such as yeast to human cells. The replisome comprises multiple protein complexes responsible for various steps in the replication process. One crucial component of the replisome is the Cdc45-MCM-GINS (CMG) helicase complex, which unwinds double-stranded DNA and coordinates the assembly and function of other replisome components, including DNA polymerases. The genes encoding the CMG helicase components are essential for initiating DNA replication. In this study, we aimed to investigate how the absence of one copy of the CMG complex genes in heterozygous Saccharomyces cerevisiae cells impacts the cells' physiology and aging. Our data revealed that these cells exhibited a significant reduction in transcript levels for the respective CMG helicase complex proteins, as well as disruptions in the cell cycle, extended doubling times, and alterations in their biochemical profile. Notably, this study provided the first demonstration that cells heterozygous for genes encoding subunits of the CMG helicase exhibited a significantly increased reproductive potential and delayed chronological aging. Additionally, we observed a noteworthy correlation between RNA and polysaccharide levels in yeast and their reproductive potential, as well as a correlation between fatty acid levels and cell doubling times. Our findings also shed new light on the potential utility of yeast in investigating potential therapeutic targets for cancer treatment

Depletion of the Origin Recognition Complex Subunits Delays Aging in Budding Yeast

Precise DNA replication is pivotal for ensuring the accurate inheritance of genetic information. To avoid genetic instability, each DNA fragment needs to be amplified only once per cell cycle. DNA replication in eukaryotes starts with the binding of the origin recognition complex (ORC) to the origins of DNA replication. The genes encoding ORC subunits have been conserved across eukaryotic evolution and are essential for the initiation of DNA replication. In this study, we conducted an extensive physiological and aging-dependent analysis of heterozygous cells lacking one copy of ORC genes in the BY4743 background. Cells with only one copy of the ORC genes showed a significant decrease in the level of ORC mRNA, a delay in the G1 phase of the cell cycle, and an extended doubling time. Here, we also show that the reducing the levels of Orc1-6 proteins significantly extends both the budding and average chronological lifespans. Heterozygous ORC/orcΔ and wild-type diploid cells easily undergo haploidization during chronological aging. This ploidy shift might be related to nutrient starvation or the inability to survive under stress conditions. A Raman spectroscopy analysis helped us to strengthen the hypothesis of the importance of lipid metabolism and homeostasis in aging