18,725 research outputs found
Spin Structure of the Nucleon - Status and Recent Results
After the initial discovery of the so-called "spin crisis in the parton
model" in the 1980's, a large set of polarization data in deep inelastic
lepton-nucleon scattering was collected at labs like SLAC, DESY and CERN. More
recently, new high precision data at large x and in the resonance region have
come from experiments at Jefferson Lab. These data, in combination with the
earlier ones, allow us to study in detail the polarized parton densities, the
Q^2 dependence of various moments of spin structure functions, the duality
between deep inelastic and resonance data, and the nucleon structure in the
valence quark region. Together with complementary data from HERMES, RHIC and
COMPASS, we can put new limits on the flavor decomposition and the gluon
contribution to the nucleon spin. In this report, we provide an overview of our
present knowledge of the nucleon spin structure and give an outlook on future
experiments. We focus in particular on the spin structure functions g_1 and g_2
of the nucleon and their moments.Comment: 69 pages, 46 figures. Report to be published in "Progress in Particle
and Nuclear Physics". v2 with added references and minor edit
SQPR: Stream Query Planning with Reuse
When users submit new queries to a distributed stream processing system (DSPS), a query planner must allocate physical resources, such as CPU cores, memory and network bandwidth, from a set of hosts to queries. Allocation decisions must provide the correct mix of resources required by queries, while achieving an efficient overall allocation to scale in the number of admitted queries. By exploiting overlap between queries and reusing partial results, a query planner can conserve resources but has to carry out more complex planning decisions. In this paper, we describe SQPR, a query planner that targets DSPSs in data centre environments with heterogeneous resources. SQPR models query admission, allocation and reuse as a single constrained optimisation problem and solves an approximate version to achieve scalability. It prevents individual resources from becoming bottlenecks by re-planning past allocation decisions and supports different allocation objectives. As our experimental evaluation in comparison with a state-of-the-art planner shows SQPR makes efficient resource allocation decisions, even with a high utilisation of resources, with acceptable overheads
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Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines
Background: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that 15-lipoxygenase-1 (15-LOX1) and monoamine oxidase A (MAO-A) are among the five most strongly upregulated gene products in IL-4-treated cells. Transfection of monocytic cells (U937) with 15-LOX1 also induced MAO-A expression. These data suggested that 15-LOX1 products might play a role in the IL4-induced signaling cascade leading to expression of MAO-A in human monocytes. Material/Methods: To test this hypothesis we incubated wild-type and 15-LOX1-transfected U937 cells with different concentrations of either IL-4 or 15-LOX-products [13S-H(p)ODE, 15S-H(p)ETE] and quantified the expression of 15-LOX1, MAO-A, and MAO-B by activity assays and real-time RT-PCR. Results: Wild-type U937 cells express neither MAO-A nor MAO-B, but after three days of IL4 treatment, MAO-A mRNA was detected. A similar isoform-specific expression of MAO-A mRNA was observed when U937 cells were transfected with 15-LOX1 or when the cells were incubated with primary 15-LOX1 products (hydroperoxy fatty acids) or H2O2. In contrast, the corresponding hydroxy fatty acids were ineffective. Conclusions: These data indicate that increased intracellular peroxide concentrations (oxidative stress) induce MAO-A expression in monocytes/macrophages, which normally do not express the enzyme. Our findings also suggest that IL-4-induced upregulation of MAO-A expression in human peripheral monocytes may proceed via 15-LOX1-dependent and 15-LOX1-independent pathways. The biological role of MAO-A expression for monocyte function is discussed
Determination of the Telluric Water Vapor Absorption Correction for Astronomical Data Obtained from the Kuiper Airborne Observatory
The amount of telluric water vapor along the line of sight of the Kuiper Airborne Observatory telescope as obtained concommitantly on 23 flights is compared with the NASA-Ames Michelson interferometer and with the NOAA-Boulder radiometer. A strong correlation between the two determinations exists, and a method for computing the atmospheric transmission for a given radiometer reading is established
The Skylab concentrated atmospheric radiation project
The author has identified the following significant results. Comparison of several existing infrared radiative transfer models under somewhat controlled conditions and with atmospheric observations of Skylab's S191 and S192 radiometers illustrated that the models tend to over-compute atmospheric attenuation in the window region of the atmospheric infrared spectra
Gaia Stellar Kinematics in the Head of the Orion A Cloud: Runaway Stellar Groups and Gravitational Infall
This work extends previous kinematic studies of young stars in the Head of
the Orion A cloud (OMC-1/2/3/4/5). It is based on large samples of infrared,
optical, and X-ray selected pre-main sequence stars with reliable radial
velocities and Gaia-derived parallaxes and proper motions. Stellar kinematic
groups are identified assuming they mimic the motion of their parental gas.
Several groups are found to have peculiar kinematics: the NGC 1977 cluster and
two stellar groups in the Extended Orion Nebula (EON) cavity are caught in the
act of departing their birthplaces. The abnormal motion of NGC 1977 may have
been caused by a global hierarchical cloud collapse, feedback by massive Ori
OB1ab stars, supersonic turbulence, cloud-cloud collision, and/or slingshot
effect; the former two models are favored by us. EON groups might have
inherited anomalous motions of their parental cloudlets due to small-scale
`rocket effects' from nearby OB stars. We also identify sparse stellar groups
to the east and west of Orion A that are drifting from the central region,
possibly a slowly expanding halo of the Orion Nebula Cluster. We confirm
previously reported findings of varying line-of-sight distances to different
parts of the cloud's Head with associated differences in gas velocity.
Three-dimensional movies of star kinematics show contraction of the groups of
stars in OMC-1 and global contraction of OMC-123 stars. Overall, the Head of
Orion A region exhibits complex motions consistent with theoretical models
involving hierarchical gravitational collapse in (possibly turbulent) clouds
with OB stellar feedback.Comment: Accepted for publication in MNRAS. 26 pages, 13 figures. The two 3-D
stellar kinematic movies, aimed as Supplementary Materials, can be found on
YouTube at: https://youtu.be/B4GHCVvCYfo (`restricted' sample) and
https://youtu.be/6fUu8sP0QFI (`full' sample
Cavitation Scaling Experiments with Axisymmetric Bodies
Several experiments by Ceccio and Brennen (1991, 1989) and Kumar and Brennen (1992, 1991) have closely examined the interaction between individual cavitation bubbles and the boundary layer, as well as statistical properties of the acoustical signals produced by the bubble collapse. All of these experiments were, however, conducted in the same facility with the same headform size (5.08cm in diameter) and over a fairly narrow range of flow velocities (around 9m/s). Clearly this raises the issue of how the phenomena identified change with speed, scale and facility. The present paper describes experiments conducted in order to try to answer some of these important questions regarding the scaling of the cavitation phenomena. The experiments were conducted in the Large Cavitation Channel of the David Taylor Research Center in Memphis Tennessee, on geometrically similar Schiebe headforms which are 5.08, 25.4 and 50.8cm in diameter for speeds ranging up to 15m/s and for a range of cavitation numbers
A nonlinear model dynamics for closed-system, constrained, maximal-entropy-generation relaxation by energy redistribution
We discuss a nonlinear model for the relaxation by energy redistribution
within an isolated, closed system composed of non-interacting identical
particles with energy levels e_i with i=1,2,...,N. The time-dependent
occupation probabilities p_i(t) are assumed to obey the nonlinear rate
equations tau dp_i/dt=-p_i ln p_i+ alpha(t)p_i-beta(t)e_ip_i where alpha(t) and
beta(t) are functionals of the p_i(t)'s that maintain invariant the mean energy
E=sum_i e_ip_i(t) and the normalization condition 1=sum_i p_i(t). The entropy
S(t)=-k sum_i p_i(t) ln p_i(t) is a non-decreasing function of time until the
initially nonzero occupation probabilities reach a Boltzmann-like canonical
distribution over the occupied energy eigenstates. Initially zero occupation
probabilities, instead, remain zero at all times. The solutions p_i(t) of the
rate equations are unique and well-defined for arbitrary initial conditions
p_i(0) and for all times. Existence and uniqueness both forward and backward in
time allows the reconstruction of the primordial lowest entropy state. The time
evolution is at all times along the local direction of steepest entropy ascent
or, equivalently, of maximal entropy generation. These rate equations have the
same mathematical structure and basic features of the nonlinear dynamical
equation proposed in a series of papers ended with G.P.Beretta, Found.Phys.,
17, 365 (1987) and recently rediscovered in S. Gheorghiu-Svirschevski,
Phys.Rev.A, 63, 022105 and 054102 (2001). Numerical results illustrate the
features of the dynamics and the differences with the rate equations recently
considered for the same problem in M.Lemanska and Z.Jaeger, Physica D, 170, 72
(2002).Comment: 11 pages, 7 eps figures (psfrag use removed), uses subeqn, minor
revisions, accepted for Physical Review
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The impact of fruit flavonoids on memory and cognition
There is intense interest in the studies related to the potential of phytochemical-rich foods to prevent age-related neurodegeneration and cognitive decline. Recent evidence has indicated that a group of plant-derived compounds known as flavonoids may exert particularly powerful actions on mammalian cognition and may reverse age-related declines in memory and learning. In particular, evidence suggests that foods rich in three specific flavonoid sub-groups, the flavanols, anthocyanins and/or flavanones, possess the greatest potential to act on the cognitive processes. This review will highlight the evidence for the actions of such flavonoids, found most commonly in fruits, such as apples, berries and citrus, on cognitive behaviour and the underlying cellular architecture. Although the precise mechanisms by which these flavonoids act within the brain remain unresolved, the present review focuses on their ability to protect vulnerable neurons and enhance the function of existing neuronal structures, two processes known to be influenced by flavonoids and also known to underpin neuro-cognitive function. Most notably, we discuss their selective interactions with protein kinase and lipid kinase signalling cascades (i.e. phosphoinositide-3 kinase/Akt and mitogen-activated protein kinase pathways), which regulate transcription factors and gene expression involved in both synaptic plasticity and cerebrovascular blood flow. Overall, the review attempts to provide an initial insight into the potential impact of regular flavonoid-rich fruit consumption on normal or abnormal deteriorations in cognitive performance
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