132 research outputs found
The electronic specific heat in the pairing pseudogap regime
When pairing correlations in a quasi two dimensional electron system induce a
pseudogap in the single particle density of states, the specific heat must also
contain a sizeable pair contribution. The theoretically calculated specific
heat for such a system is compared to the experimental results of Loram and his
collaborators for underdoped YBa_2Cu_3O_{6+x} and La_{2-x}Sr_{x}CuO_4 samples.
The size and doping dependence of the extracted pseudogap energy scale for both
materials is comparable to the values obtained from a variety of other
experiments.Comment: 4 pages, 5 eps figure
The WITCH experiment: Acquiring the first recoil ion spectrum
The standard model of the electroweak interaction describes beta-decay in the
well-known V-A form. Nevertheless, the most general Hamiltonian of a beta-decay
includes also other possible interaction types, e.g. scalar (S) and tensor (T)
contributions, which are not fully ruled out yet experimentally. The WITCH
experiment aims to study a possible admixture of these exotic interaction types
in nuclear beta-decay by a precise measurement of the shape of the recoil ion
energy spectrum. The experimental set-up couples a double Penning trap system
and a retardation spectrometer. The set-up is installed in ISOLDE/CERN and was
recently shown to be fully operational. The current status of the experiment is
presented together with the data acquired during the 2006 campaign, showing the
first recoil ion energy spectrum obtained. The data taking procedure and
corresponding data acquisition system are described in more detail. Several
further technical improvements are briefly reviewed.Comment: 11 pages, 6 figures, conference proceedings EMIS 2007
(http://emis2007.ganil.fr), published also in NIM B:
doi:10.1016/j.nimb.2008.05.15
Grupo escolar en Béthusy, Suiza
Este grupo escolar se encuentra enclavado en la calle Béthusy, ocupando la manzana comprendida entre las calles Maturin Cordier y Edouard Payot, al norte del colegio antiguo
Pair Phase Fluctuations and the Pseudogap
The single-particle density of states and the tunneling conductance are
studied for a two-dimensional BCS-like Hamiltonian with a d_{x^2-y^2}-gap and
phase fluctuations. The latter are treated by a classical Monte Carlo
simulation of an XY model. Comparison of our results with recent scanning
tunneling spectra of Bi-based high-T_c cuprates supports the idea that the
pseudogap behavior observed in these experiments can be understood as arising
from phase fluctuations of a d_{x^2-y^2} pairing gap whose amplitude forms on
an energy scale set by T_c^{MF} well above the actual superconducting
transition.Comment: 5 pages, 6 eps-figure
Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?
Background: Several c-MET targeting inhibitory molecules have already shown promising results in the treatment of patients with Non-small Cell Lung Cancer (NSCLC). Combination of EGFR-and c-MET-specific molecules may overcome EGFR tyrosine kinase inhibitor (TKI) resistance. The aim of this study was to allow for the identification of patients who might benefit from TKI treatments targeting MET and to narrow in on the diagnostic assessment of MET. Methods: 222 tumor tissues of patients with NSCLC were analyzed concerning c-MET expression and activation in terms of phosphorylation (Y1234/1235 and Y1349) using a microarray format employing immunohistochemistry (IHC). Furthermore, protein expression and MET activation was correlated with the amplification status by Fluorescence in Situ Hybridization (FISH). Results: Correlation was observed between phosphorylation of c-MET at Y1234/1235 and Y1349 (spearman correlation coefficient r(s) = 0.41;p 0.05). c-MET gene amplification was detected in eight of 214 patients (3.7 %). No significant association was observed between c-MET amplification, c-MET protein expression and phosphorylation. Conclusion: Our data indicate, that neither expression of c-MET nor the gene amplification status might be the best way to select patients for MET targeting therapies, since no correlation with the activation status of MET was observed. We propose to take into account analyzing the phosphorylation status of MET by IHC to select patients for MET targeting therapies. Signaling of the receptor and the activation of downstream molecules might be more crucial for the benefit of therapeutics targeting MET receptor tyrosine kinases than expression levels alone
The effectiveness of constraint-led training on skill development in interceptive sports: a systematic review (Clark, McEwan and Christie) – a commentary
Clark, McEwan and Christie's systematic review1 offers a timely examination of current literature assessing effects of a constraints-led approach (CLA) to training on ‘technical and cognitive skill in sport’, in comparison to traditional training methods. They concluded that, currently, there is strong evidence to advocate for the effects of training interventions that espouse benefits of constraints-led training on acquiring skill in interceptive actions. Clark, McEwan and Christie reported that 18 studies satisfied their proposed inclusion criteria and, of these studies, 77% provided evidence of the effectiveness of the CLA. Consequently, Clark, McEwan and Christie argued that a ‘the implementation of the constraints-led approach within interceptive sport can be advocated’ (p. 17). This is a revealing insight, which supports their claims that this finding ‘provides the opportunity for researchers to collect more compelling evidence to answer the question: “Does constraint-led training assist with the development of technical skills within interceptive sport?”’. While we endorse their call for more empirical evidence on the effectiveness of a CLA to practice and training design, we qualify it by highlighting some limitations of Clark, McEwan and Christie's systematic review
Calibration of the ISOLDE acceleration voltage using a high-precision voltage divider and applying collinear fast beam laser spectroscopy
A high-voltage divider with accuracy at the ppm level and collinear laser
spectroscopy were used to calibrate the highvoltage installation at the
radioactive ion beam facility ISOLDE at CERN. The accurate knowledge of this
voltage is particularly important for collinear laser spectroscopy
measurements. Beam velocity measurements using frequencycomb based collinear
laser spectroscopy agree with the new calibration. Applying this, one obtains
consistent results for isotope shifts of stable magnesium isotopes measured
using collinear spectroscopy and laser spectroscopy on laser-cooled ions in a
trap. The long-term stability and the transient behavior during recovery from a
voltage dropout were investigated for the different power supplies currently
applied at ISOLDE.Comment: 13 pages, 6 figure
Electronic structure of the trilayer cuprate superconductor BiSrCaCuO
The low-energy electronic structure of the trilayer cuprate superconductor
BiSrCaCuO near optimal doping is investigated by
angle-resolved photoemission spectroscopy. The normal state quasiparticle
dispersion and Fermi surface, and the superconducting d-wave gap and coherence
peak are observed and compared with those of single and bilayer systems. We
find that both the superconducting gap magnitude and the relative
coherence-peak intensity scale linearly with for various optimally doped
materials. This suggests that the higher of the trilayer system should be
attributed to parameters that simultaneously enhance phase stiffness and
pairing strength.Comment: 5 pages, 5 figre
Dilepton production in pp and CC collisions with HADES
Dilepton production has been measured with HADES, the "High Acceptance
DiElectron Spectrometer". In pp collisions at 2.2GeV kinetic beam energy,
exclusive eta production and the Dalitz decay eta -> gamma e+e- has been
reconstructed. The electromagnetic form factor is well in agreement with
existing data. In addition, an inclusive e+e- spectrum from the C+C reaction at
2AGeV is presented and compared with a thermal model.Comment: 11 pages, 3 figures, proceedings of the IVth International Conference
on Quarks and Nuclear Physics, Madrid, June 5th-10th, submitted to
Eur.Phys.J.
Challenges in QCD matter physics - The Compressed Baryonic Matter experiment at FAIR
Substantial experimental and theoretical efforts worldwide are devoted to
explore the phase diagram of strongly interacting matter. At LHC and top RHIC
energies, QCD matter is studied at very high temperatures and nearly vanishing
net-baryon densities. There is evidence that a Quark-Gluon-Plasma (QGP) was
created at experiments at RHIC and LHC. The transition from the QGP back to the
hadron gas is found to be a smooth cross over. For larger net-baryon densities
and lower temperatures, it is expected that the QCD phase diagram exhibits a
rich structure, such as a first-order phase transition between hadronic and
partonic matter which terminates in a critical point, or exotic phases like
quarkyonic matter. The discovery of these landmarks would be a breakthrough in
our understanding of the strong interaction and is therefore in the focus of
various high-energy heavy-ion research programs. The Compressed Baryonic Matter
(CBM) experiment at FAIR will play a unique role in the exploration of the QCD
phase diagram in the region of high net-baryon densities, because it is
designed to run at unprecedented interaction rates. High-rate operation is the
key prerequisite for high-precision measurements of multi-differential
observables and of rare diagnostic probes which are sensitive to the dense
phase of the nuclear fireball. The goal of the CBM experiment at SIS100
(sqrt(s_NN) = 2.7 - 4.9 GeV) is to discover fundamental properties of QCD
matter: the phase structure at large baryon-chemical potentials (mu_B > 500
MeV), effects of chiral symmetry, and the equation-of-state at high density as
it is expected to occur in the core of neutron stars. In this article, we
review the motivation for and the physics programme of CBM, including
activities before the start of data taking in 2022, in the context of the
worldwide efforts to explore high-density QCD matter.Comment: 15 pages, 11 figures. Published in European Physical Journal
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