Edukacja emocjonalna adolescentów – program profilaktyczny ukierunkowany na wspomaganie zdrowia psychicznego

Adolescence is a time of particular susceptibility to mental disorders. A programme aimed at facilitating emotional development in teenagers might be an important element of prophylactic psychopathology targeting young people. The activities proposed here are group activities and have several aims: to develop the ability to become self-aware regarding one's emotions and regulate their intensity; to foster an attitude of caring for oneself; and to teach problem-solving. What is of particular significance is shaping young people’s habits in being proactive in their personal development.Adolescence is a time of particular susceptibility to mental disorders. A programme aimed at facilitating emotional development in teenagers might be an important element of prophylactic psychopathology targeting young people. The activities proposed here are group activities and have several aims: to develop the ability to become self-aware regarding one's emotions and regulate their intensity; to foster an attitude of caring for oneself; and to teach problem-solving. What is of particular significance is shaping young people’s habits in being proactive in their personal development

Cortisol in Correlation to Other Indicators of Fish Welfare

Cortisol is the major corticosteroid in teleost fish, secreted and released by interrenal cells of the head kidney during activation of the hypothalamic-pituitary-interrenal (HPI) axis. Although cortisol is universally recognized as a key mediator of stress-associated responses, other hormones are also involved in the stress response, e.g., arginine vasotocin (AVT), isotocin (IT), urotensins, dopamine, serotonin or β-endorphin. Cortisol affects AVT and IT secretion from nerve endings in gilthead sea bream (Sparus aurata) and round goby (Neogobius melanostomus). Moreover, it is pointed out that different mechanisms are involved in the regulation of AVT and IT release from the hypothalamic-pituitary complex in round goby. In the case of AVT, both genomic and nongenomic pathways are mediating the effect of cortisol while in the case of IT, it is only the nongenomic pathway. In turn, urotensin I instead of corticotropin-releasing factor (CRF) may contribute to the regulation of HPI axis and regulate AVT in Sparus aurata. In this species, urotensin II together with AVT and IT may control stress response to different salinities. Therefore, AVT, IT and urotensins, and their interactions with cortisol, seem to be significant in response to stress in fish

Social factors determining 5–6 year-old children’s absorption of aggressive behavioural patterns from television programs

The article presents research results concerning social factors determining 5-6-year-olds’ absorption of aggressive behavioural patterns from television programs. The study was conducted among pre-school children in three settings: cities, towns and rural areas. The findings refer to the influence of various social factors, such as family, peer community and place of residence, on children’s aggressive behaviour

Immunolocalization of CGRP, NPY and PGP 9.5 in guinea pig skin

By means of immunoperoxidase and immune-alkaline phosphatase methods the immunoreactivities to neuropeptides: neuropeptide Y (NPY), calcitonin gene related peptide (CGRP) and a pan-neuronal marker, the protein gene product 9.5 (PGP 9.5), were evaluated in guinea pig deep dorsal skin specimens. CGRP immunoreactive (CGRP-IR) and NPY-immunoreactive (NPY-IR) nerve fibres were dispersed in the papillary dermis and sometimes inside the hair roots and among the sebaceous gland cells. Such localized nerve fibres have not so far been described. In the subcutaneous layer nerve trunks were found composed of CGRP-IR and NPY-IR nerve fibres. Some of these indicated vestigial or negative immunoreactivity to PGP 9.5

Somatostatin receptors in human adrenal gland tumors--immunohistochemical study.

Somatostatin receptors subtypes (SSTR 1-5) were demonstrated in surgically obtained adrenal gland tumors by means of immunohistochemistry (IHC). Results of the present study demonstrate that somatostatin receptors are expressed in adrenal tumors in a varied manner which is specific in each case. It provides different diagnostic and therapeutic possibilities

Personal Development Group for Parents of Young People with Mental Disorders – Report of Activities

Parents whose children have been diagnosed with mental/emotional disorders need support in the process of coping with their difficult life situation. Such help could enable them to adequately reinforce their children’s development as well as increase the whole family’s chance to wipe out the life crisis. One of the valuable methods of support could be personal development group for parents. The purpose of the present thesis is to present the theoretical foundations, the course and the outcome of the work of the personal development group for parents of young people with mental disorders. The group in question was a closed one and included 8 people. The program scheduled 10 weekly meetings. The work was focused on the following issues: the acceptance of the child’s diagnosis, placing the experience of the disease in the child’s and family’s life stories, self-esteem and the ways to reinforce it, communication within the family, setting boundaries between the family subsystems, interpretation and understanding of emotions, personal convictions about parenthood, the search of one’s own resources as well as those concerning the whole family and the widely understood social system. The work within the group was inspired by the methods of existential psychology and narrative psychology. The participants’ tasks included telling and listening to the stories of the key-events of their lives as well as searching the personal meaning of the particular life experiences. The recap of the paper presents the chosen insights and conclusions obtained afoot the work with the described group.3632734519Studia Edukacyjn

Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors

<p><strong> </strong></p><p><strong><em>Objectives</em></strong>. Follicle stimulating hormone (FSH) receptors (FSHR) are physiologically expressed in the ovary and testis. It is well known that FSHR are also expressed in gonadal cancers, but the data on their incidence in extra-gonadal tumors are scarce. Recently, the expression of FSHR in the vascular endothelium within different human cancers was found, but nothing is known on FSHR appearance in non-gonadal endocrine tumors. The present paper reports on the immunohistochemical detection of FSHR in human pituitary adenomas and adrenal tumors.</p><p><strong>Materials and methods</strong>. The study included samples of 28 pituitary adenomas and 36 adrenal tumors. Moreover, 2 samples of non-tumoral adrenal glands were also studied.</p><p>FSH receptor immunostaining was performed on paraffin sections using the rabbit anti-human FSH-R polyclonal antibody raised against 1-190 amino acid sequence from the human FSH-R (sc-13935). The pituitary adenomas were immunostained to reveal the pituitary hormones and the proliferation marker Ki-67.</p><p><strong>Results</strong>. In the pituitary adenomas, positive immunostaining with anti-FSHR antibody occurred in the adenoma cells cytoplasm and endothelia of the intra- and peritumoral blood vessels. The cytoplasmic immunostaining was found in the majority of investigated tumors but the intensity of staining was weak to moderate. There is some tendency towards the higher cytoplasmic FSHR score in tumors with higher Ki-67 index (atypical adenomas). In contrast to the cytoplasm, the FSHR immunostaining in blood vessels is strong and concerns all the investigated samples. Strong FSHR immunostaining is present in the endothelium of intra- and/or peritumoral blood vessels in the majority of pheochromocytomas, approximatively one half of the adrenocortical adenomas and both cases of the adrenal cancers. The immunostaining is detectable also in the tumoral cell cytoplasm in all but one examined pheochromocytomas.. All the investigated adrenocortical adenomas presented strong immunostaining of cell membranes. No immunostained cell membranes were found. in adrenal cancers. The positive immunostaining was found in glandular cells, but not in blood vessels, of non-tumoral adrenal cortex and medulla.</p><strong>Conclusions</strong>. Immunostaining of FSHR often occurs in the endothelium of intra- and/or peritumoral blood vessels of pituitary adenomas and benign and malignant adrenal tumors. The immunostaining may be also present in tumoral cells. A role of FSHR expression in these tumors (stimulation of angiogenesis? stimulation of cell growth?) needs further studies to be clarified

Expression of somatostatin receptor subtypes in human thyroid tumors: the immunohistochemical and molecular biology (RT-PCR) investigation

Human endocrine tumors often express the somatostatin receptors SSTR 1–5 with different intensity. It has been widely investigated their distribution in pituitary adenomas, brain tumors, adrenal tumors and neuroendocrine tumors in gastrointestinal tract (NET). Some of studies also concern the expression of SSTRs in thyroid tumors but they are mainly limited to parafollicular C cells – derived medullary thyroid carcinomas (MTC). Results of SSTR 1–5 detection in other thyroid pathologies like follicular adenomas and papillary cancers are still scarce and often controversial, depending of investigation method used. The aim of this study was to report the presence of all the 5 subtypes of SSTR (including 2A and 2B SSTR isoforms) in some surgically treated human thyroid tumors by means of immunohistochemistry and real-time PCR method and to correlate the results obtained with both techniques. SSTR 1 protein was expressed in 88.8% of investigated cases, SSTR 2A and 2B both in 44.4%, SSTR 3 in 55.5%, SSTR 4 in 11.2% and SSTR 5 in 33.3%. SSTR 1 is the dominant form in the thyroid gland tumor and hyperplasia. We found positive confirmation of both methods in 88.8% for SSTR 1, 2A, 3 subtypes, in 22.2% for SSTR 4 and in 100% for SSTR 5. It suggests that somatostatin multiligand analogs or selective SSTR 1 agonists may be used in thyroid tumors treatment

Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors

Objectives. Follicle stimulating hormone (FSH) receptors (FSHR) are physiologically expressed in the ovary and testis. It is well known that FSHR are also expressed in gonadal cancers, but the data on their incidence in extra-gonadal tumors are scarce. Recently, the expression of FSHR in the vascular endothelium within different human cancers was found, but nothing is known on FSHR appearance in non-gonadal endocrine tumors. The present paper reports on the immunohistochemical detection of FSHR in human pituitary adenomas and adrenal tumors.Materials and methods. The study included samples of 28 pituitary adenomas and 36 adrenal tumors. Moreover, 2 samples of non-tumoral adrenal glands were also studied.FSH receptor immunostaining was performed on paraffin sections using the rabbit anti-human FSH-R polyclonal antibody raised against 1-190 amino acid sequence from the human FSH-R (sc-13935). The pituitary adenomas were immunostained to reveal the pituitary hormones and the proliferation marker Ki-67.Results. In the pituitary adenomas, positive immunostaining with anti-FSHR antibody occurred in the adenoma cells cytoplasm and endothelia of the intra- and peritumoral blood vessels. The cytoplasmic immunostaining was found in the majority of investigated tumors but the intensity of staining was weak to moderate. There is some tendency towards the higher cytoplasmic FSHR score in tumors with higher Ki-67 index (atypical adenomas). In contrast to the cytoplasm, the FSHR immunostaining in blood vessels is strong and concerns all the investigated samples. Strong FSHR immunostaining is present in the endothelium of intra- and/or peritumoral blood vessels in the majority of pheochromocytomas, approximatively one half of the adrenocortical adenomas and both cases of the adrenal cancers. The immunostaining is detectable also in the tumoral cell cytoplasm in all but one examined pheochromocytomas.. All the investigated adrenocortical adenomas presented strong immunostaining of cell membranes. No immunostained cell membranes were found. in adrenal cancers. The positive immunostaining was found in glandular cells, but not in blood vessels, of non-tumoral adrenal cortex and medulla.Conclusions. Immunostaining of FSHR often occurs in the endothelium of intra- and/or peritumoral blood vessels of pituitary adenomas and benign and malignant adrenal tumors. The immunostaining may be also present in tumoral cells. A role of FSHR expression in these tumors (stimulation of angiogenesis? stimulation of cell growth?) needs further studies to be clarified

Stymulowanie rozwoju percepcji słuchowej małych dzieci z mózgowym porażeniem

The text tackles the issue of stimulation of auditory perception in small children with cerebral palsy. Parents and specialists are able to use different methods to enhance the communication competence of small children which takes into consideration various needs of the child stemming from different areas of its development. In text there are some propositions of exercises, which could be done in everyday situations and which are attractive for small children; the aim of them is to develop auditory perception.The text tackles the issue of stimulation of auditory perception in small children with cerebral palsy. Parents and specialists are able to use different methods to enhance the communication competence of small children which takes into consideration various needs of the child stemming from different areas of its development. In text there are some propositions of exercises, which could be done in everyday situations and which are attractive for small children; the aim of them is to develop auditory perception