Role of isoflavones and its derivatives on the growth of Aspergillus niger and Rhizactonia solani

Two naturally occurring isoflavones genistine and biochanin - A, and their dihydro derivatives (isoflavones) as well as nine perhydroginated isoflavones (isoflavanes) were tested for their effects on mycelial growth of two soil fungi viz., Aspergillus niger and Rhizactonia solani. All the isoflavonenoids of the biochanin - A series showed the genistine isoflavane and the other isoflavanes with two hydroxyl groups and one methoxy groupe are fungi toxic, while isoflavones with two and one methoxy group were almost inactive

The role of phytohormone on the production of berberine in the calli cultures of an endangered medicinal plant, turmeric (Coscinium fenestratum l.)

The present report for the first time describes the results of study aimed at evaluation of the role of phytohormones on the production of berberine from in vitro calli cultures. Calli cultures derived fromleaf and petiole explants were established in MS medium supplemented with 2,4-dichlorophenoxy acetic acid (2,4-D) plus 6-benzylaminopurine (BAP) and/or kinetin (KN). Berberine an isoquinoline alkaloid, was isolated from 6 - 7 week old calli cultures. Media, phytohormones, and explants used influenced the biomass and berberine content in calli cultures. Berberine with the retention time of 8.49 min and enhanced dry weight (1.788%) from the petiole explant is reported for the first time in thisstudy. The presence of berberine was first checked by preparative thin layer chromatography (TLC) and then confirmed by High Pressure Liquid chromatography (HPLC) and mass spectrometry. Chemical structure was determined through proton NMR and 13C spectra

Role of isoflavones and its derivatives on the growth of Pseudomonas putida and Escherichia coli

Two naturally occurring isoflavones genistine and biochanin - A, and their dihydro derivatives (isoflavones) as well as nine perhydroginated isoflavones (isoflavanes) were tested for their effects on mycelial growth of two soil bacteria viz., Pseudomonas putida and Escherichia coli. All the isoflavonenoids of the biochanin - A series showed the genistine isoflavane and the other isoflavanes with two hydroxyl groups and one methoxy groups are toxic, while isoflavones with two and one methoxy group were almost inactive. Genistein, a radio protective soy isoflavone and protein kinase inhibitor, blocks the invasion of pathogenic bacteria in mammalian epithelial cells. The purpose of this study was to evaluate the direct effect of genistein on the survival and growth of the probiotic Lactobacillus reuteri and selected opportunistic bacteria in vitro as a prelude to in vivo use for managing post irradiation sepsis. The opportunistic bacterial enteropathogens viz., Escherichia coli, Shigella sonnei, and Staphylococcus aureus as well as Klebsiella pneumoniae and the non-pathogenic organism, Bacillus anthracis (Sterne) were evaluated. The latter two bacteria are found in the environment and may be of concern in irradiated individuals. A standard in vitro test was employed to evaluate the direct effect of genistein on the bacteria

Cor triloculare biventriculare with left superior vena cava

Cor triloculare biventriculare is a rare congenital malformation of the heart in which there is a complete absence of the atrial septum. It is usually associated with other anomalies like complete atrioventricular canal defect, polysplenic syndrome, isolated dextrocardia, Ellis-van Creveld syndrome, or persistent left superior vena cava. We report a case of a stillborn male foetus of 35 weeks gestation with common atrium, complete atrioventricular canal defect, and persistent left superior vena cava. The possible embryological basis and clinical implication of this variation are discussed. (Folia Morphol 2011; 70, 2: 135–138

A viable multivariable adaptive controller with application to autonomous helicopters

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2001.Includes bibliographical references (p. 116-122).Autonomous helicopters carry out missions in inaccessible hazardous environments. Their performance capability in speed, maneuverability and trajectory tracking must be comparable, if not superior, to manned vehicles. Control laws that meet desired performance specifications are difficult to design because of the uncertain, fully-coupled nonlinear dynamics of autonomous helicopters. Uncertainties in helicopter parameters not only change the dynamics of the system but the trim inputs themselves. Many of the current control designs assume low speeds and neglect aerodynamics as well as uncertainties in system parameters. As a result, these linear and nonlinear controllers are adequate at best at hover, and therefore not viable in real plants, as the unknown trim conditions and dynamics result in severe performance degradation even at moderate speeds. For an autonomous vehicle control system to be viable, it must accommodate uncertainties in the trim conditions on-line, the effect of the aerodynamics, and parametric uncertainties, for various realistic maneuvers beyond hover. This thesis presents a viable multivariable adaptive control design methodology that is applicable to the needs of uncertain plants and high bandwidth requirements. Control in the cases where the full and partial state variables are available for measurement are considered. A systematic control design procedure that fully accommodates the aerodynamics of the autonomous vehicle is developed. The principal features of the proposed controller are the following: The multivariable adaptive controller accommodates both parametric uncertainties and unknown trim conditions through on-line adjustment of appropriate control parameters.(cont.) parameters. Closed-loop stability and robustness are demonstrated through the use of suitable Lyapunov functions. Judicious integration between linear robust control methods and online adaptive strategies is incorporated in the control design to maximize off-line information about the nominal conditions and on-line measurements. A two-step nonlinear optimization procedure is carried out to determine nominal trim states that allows the arbitrarily close convergence to the global minima by making use of prior information available about sub-components of the trim states during a given maneuver. The control design methodology is tested on a high fidelity simulation of a Draper Laboratory autonomous helicopter. Extensive simulation studies were carried out, beginning from a vehicle model that includes complete vehicle aerodynamics, gravitational and inertial effects, rotor dynamics, and rotor-vehicle interactions. Five different inputs including the roll-cyclic and pitch cyclic angles of the main rotor, the pedal command for the tail rotor, collective pitch angle for the main rotor, and the throttle are assumed to be present. The controller is evaluated at various operating conditions and maneuvers where aerodynamic nonlinearities and parametric uncertainties become dominant. Simulations are performed on a nonlinear longitudinal dynamics model to track step and sinusoidal changes in forward flight velocity, and a maneuver involving jumps over hurdles. Simulations on the full three dimensional nonlinear helicopter model are performed for vertical flight and coordinated turn maneuvers ...by Ashish Samuel Krupadanam.Ph.D

The effect of wheat protein concentrate supplementation upon sorghum diets as measured by rat performance

Call number: LD2668 .T4 1969 K6Master of Scienc

Baker's yeast catalysed enantioselective reduction of chroman-4-ones

1119-112

A facile synthesis of ethyl 2-methyl-5-oxo-5H-[1]benzopyrano[3,4-c]pyridine-carboxylates

686-68

A facile synthesis of 2-[4'-(2', 6' -dimethyl-3',5' –dicarbethoxy-1’,4'-dihydropyridyl)]chromones

965-96

A new synthesis of heterocyclic compounds with 1,5-benzodioxapine, 1,5- benzodiazepine, 1,5-benzothiazepine ring systems

34-3