Effect of maternal panic disorder on mother-child interaction and relation to child anxiety and child self-efficacy

To determine whether mothers with panic disorder with or without agoraphobia interacted differently with their children than normal control mothers, 86 mothers and their adolescents (aged between 13 and 23 years) were observed during a structured play situation. Maternal as well as adolescent anxiety status was assessed according to a structured diagnostic interview. Results showed that mothers with panic disorder/agoraphobia showed more verbal control, were more criticizing and less sensitive during mother-child interaction than mothers without current mental disorders. Moreover, more conflicts were observed between mother and child dyadic interactions when the mother suffered from panic disorder. The comparison of parenting behaviors among anxious and non-anxious children did not reveal any significant differences. These findings support an association between parental over-control and rejection and maternal but not child anxiety and suggest that particularly mother anxiety status is an important determinant of parenting behavior. Finally, an association was found between children’s perceived self-efficacy, parental control and child anxiety symptoms

Implementing structured functional assessments in general practice for persons with long-term sick leave: a cluster randomised controlled trial

<p>Abstract</p> <p>Background</p> <p>The increasing attention on functional assessments in medical and vocational rehabilitation requires a focus change for the general practitioners (GP) into paying attention to patient resources, possibilities and coping instead of symptoms, problems and limitations. The GPs report difficulties in performing the requested explicit functional assessments. The purpose of this study was to implement a structured method in general practice for assessing functional ability in persons with long-term sick leave. The study aim was to evaluate intervention effects on important GP parameters; knowledge, attitudes, self-efficacy towards functional assessments and knowledge about patient work factors.</p> <p>Methods</p> <p>Fifty-seven GPs were randomly assigned to an intervention or a control group. The intervention group GPs attended an introductory one-day work-shop and implemented structured functional assessments during an eight months intervention period. GP knowledge, GP attitudes, and GP self-efficacy towards functional assessments, as well as GP knowledge of patient work factors, were collected before, after and six months after the intervention period started. Evaluation score-sheets were filled in by both the intervention GPs and their patients immediately after the consultation to evaluate the GPs' knowledge of patient work factors.</p> <p>Results</p> <p>The intervention GPs reported increased knowledge (B: 0.56, 95% CI (0.19, 0.91)) and self-efficacy (B: 0.90, 95% CI (0.53, 1.26)) towards functional assessments, and increased knowledge about their patients' workplace (B: 0.75, 95% CI (0.35, 1.15)) and perceived stressors (B: 0.55, 95% CI (0.23, 0.88)) with lasting effects at the second follow-up. No intervention effect was seen in relation to GP attitudes. Both before and after the intervention, the GPs were most informed about physical stressors, and less about mental and work organisational stressors (Guttman's reproducibility coefficient: 0.95 and 1.00). After the consultation, both the intervention GPs and their patients reported that the GPs' knowledge about patient work factors had increased (GP B: 0.60 (95% CI: 0.42, 0.78); patient B: 0.50 (95% CI: 0.34, 0.66)).</p> <p>Conclusion</p> <p>Introducing and implementing structured functional assessments in general practice made the GPs capable to assess functional ability of their patients in a structured manner. Intervention effects of increased GP knowledge and GP self-efficacy sustained at the second follow-up.</p

CONNECTING GEOLOGY AND GEOPHYSICS: THE GEODYNAMIC EVOLUTION OF DRONNING MAUD LAND FROM RODINIA TO GONDWANA

East Antarctica consists of a number of cratonic fragments that amalgamated along distinct orogenic belts in late Neoproterozoic to early Palaeozoic times. These mobile belts include the c. 640 to 500 Ma old East African-Antarctic Orogen (EAAO) and the Kuunga Orogen, which seem to converge in Dronning Maud Land in the Atlantic sector of Antarctica. The polymetamorphic basement of Dronning Maud Land is characterized by rocks with Grenville-age protolith ages of c. 1130 to 1000 Ma in the west and rocks with early Neoproterozoic protolith ages of c. 1000 to 900 Ma in the east. These two provinces are separated by the prominent Forster Magnetic Anomaly, which is therefore interpreted to represent a suture zone. Four joint AWI-BGR international expeditions within the WEGAS (West-East Gondwana Amalgamation and Separation) and GEA (Geodynamic Evolution of East Antarctica) programmes between 2010 and 2015 have provided new combined geological and geophysical data that reveal a complex crustal architecture between central Dronning Maud Land and Lützow-Holm-Bay. The magnetic anomaly pattern changes significantly east of the Forster Magnetic Anomaly with apparently no indication of Maud-type crust. Particularly, the GEA II campaign (2011-12) targeted a series of previously unvisited nunataks in the largely ice- covered Borchgrevink-Isen between central Dronning Maud Land and Sør Rondane from Urna and Sørsteinen in the west to Blåklettane and Bergekongen in the east. This region is characterized by NW-SE trending distinct linear magnetic anomalies. This pattern is referred to as the SE Dronning Maud Land Province and was previously interpreted as a fragment of potentially older cratonic crust south of an Ediacaran to Cambrian mobile belt that crops out in Sør Rondane. New SHRIMP/SIMS U-Pb zircon ages and geochemical analyses, however, indicate that this region consists of Rayner-age (c. 1000 to 900 Ma) juvenile arc and metasedimentary cover rocks, which were intensely reworked by medium- to high-grade metamorphism and felsic melt injections between c. 630 and 520 Ma. The juvenile rocks are very similar to a gabbro-tonalite-trondhjemite-granodiorite (GTTG) suite in the southern SW Terrane of Sør Rondane, which yield crystallization ages of c. 1000 to 920 Ma based on U-Pb zircon geochronology. The juvenile character of this suite suggests a long-lived accretionary setting in early Neoproterozoic times. While the rocks in the Borchgrevink-Isen further west were intensely reworked in Pan-African times, the GTTG complex in Sør Rondane shows evidence of Pan-African up to lower amphibolite-facies thermal overprint, but still contains large domains with apparently only weak deformation. An exception is the northern margin of the GTTG complex where high-strain dextral shear is related to the prominent Main Shear Zone that is estimated to be of latest Ediacaran to early Cambrian age (c. 560 to 530 Ma). This structure, which we interpret as part of a fault system related to NE-directed lateral extrusion of the EAAO, separates the Rayner-age GTTG complex from a series of greenschist- to granulite-facies metasupracrustal rocks of mainly volcano-sedimentary origin. They in turn are separated from the amphibolite- to granulite-facies NE Terrane in the north and north-east by the Main Tectonic Boundary that is postulated by researches of the Japanese National Antarctic Programme. Available literature and our own new geochronological data indicate that peak and retrograde metamorphism in the NE and SW terranes was at c. 640 to 530 Ma. Both terranes were intruded by several granitoid magmatic pulses between c. 650 and 500 Ma. In contrast to “Indo-Antarctic” affinities of the GTTG complex south of the Main Shear Zone and the similar rocks of the SE Dronning Maud Land Province to the west, these units thus appear to have rather “East African” affinities. Furthermore, grey heterogeneous gneisses and augen-gneisses of the aforementioned meta-volcanosedimentary supracrustal rocks of the SW Terrane close to the Main Shear Zone gave zircon crystallization ages of c. 750 Ma. Such ages are unknown from the EAAO in central and western Dronning Maud Land west of the Forster Magnetic Anomaly. Taking all evidence together, we propose that the Forster Magnetic Anomaly separates distinctly different parts of the EAAO. These are (i) a reworked, mainly Grenville-age crust of the Maud Belt to the west representing the overprinted margin of the Kalahari Craton, and (ii) a part of the orogen dominated by early Neoproterozoic accretionary tectonics to the east, which we refer to as Tonian Ocean Arc Super Terrane (TOAST). The contrast between these two crustal units is also reflected in the geochemistry of voluminous late-tectonic granitoids across the whole belt. Based on our new geological and aerogeophysical evidence, the regional crustal structure of eastern Dronning Maud Land as a whole may tentatively be interpreted as reflecting large-scale lateral extrusion of the EAAO post-dating continental collision in the late Neoproterozoic and early Cambrian

Farnesylated Nuclear Proteins Kugelkern and Lamin Dm0 Affect Nuclear Morphology by Directly Interacting with the Nuclear Membrane

Nuclear shape changes are observed during a variety of developmental processes, pathological conditions and ageing. Here, the molecular mechanism is analyzed how the farnesylated nuclear proteins interact with the nuclear envelope and deform the phospholipid bilayer

Tracking the impact of depression in a perspective-taking task

Research has identified impairments in Theory of Mind (ToM) abilities in depressed patients, particularly in relation to tasks involving empathetic responses and belief reasoning. We aimed to build on this research by exploring the relationship between depressed mood and cognitive ToM, specifically visual perspective-taking ability. High and low depressed participants were eye-tracked as they completed a perspective-taking task, in which they followed the instructions of a ‘director’ to move target objects (e.g. a “teapot with spots on”) around a grid, in the presence of a temporarily-ambiguous competitor object (e.g. a “teapot with stars on”). Importantly, some of the objects in the grid were occluded from the director’s (but not the participant’s) view. Results revealed no group-based difference in participants’ ability to use perspective cues to identify the target object. All participants were faster to select the target object when the competitor was only available to the participant, compared to when the competitor was mutually available to the participant and director. Eye-tracking measures supported this pattern, revealing that perspective directed participants’ visual search immediately upon hearing the ambiguous object’s name (e.g. “teapot”). We discuss how these results fit with previous studies that have shown a negative relationship between depression and ToM

Unique Roles of Mothering and Fathering in Child Anxiety; Moderation by Child’s Age and Gender

We examined the associations between the parenting dimensions autonomy granting, over control, and rejection and children’s anxiety, in relation to parent and child gender and child age. Elementary school-aged children (n = 179, Mage = 10.27, SD = 1.30), adolescents (n = 127, Mage = 15.02, SD = 1.54) and both their parents completed questionnaires on parenting and children’s anxiety. Parenting was more strongly related to child anxiety in elementary school children than in adolescents. Maternal over control was uniquely related to elementary school-aged children’s anxiety whereas paternal over control was more important during adolescence. Opposite to our expectations, we found higher levels of parental autonomy granting to be related to higher levels of anxiety for younger elementary school-aged children (age < 10). For adolescents, the association between paternal over control and anxiety was stronger for older adolescents (age > 15), with higher levels of over control related to higher levels of anxiety. For both elementary school-aged children and adolescents, the associations between parenting and child anxiety did not differ as a function of the child’s gender. If we are to understand the associations between parenting and children’s anxiety, it is important to distinguish parental autonomy granting from parental over control and to consider the role of parent gender and the age of the child

Exploring the relationship between experiential avoidance, coping functions and the recency and frequency of self-harm

This study investigated the relationship between experiential avoidance, coping and the recency and frequency of self-harm, in a community sample (N = 1332, aged 16–69 years). Participants completed online, self-report measures assessing self-harm, momentary affect, experiential avoidance and coping in response to a recent stressor. Participants who had self-harmed reported significantly higher levels of experiential avoidance and avoidance coping, as well as lower levels of approach, reappraisal and emotional regulation coping, than those with no self-harm history. Moreover, more recent self-harm was associated with lower endorsement of approach, reappraisal and emotion regulation coping, and also higher levels of both avoidance coping and experiential avoidance. Higher experiential avoidance and avoidance coping also predicted increased lifetime frequency of self-harm. Conversely, increased approach and reappraisal coping were associated with a decreased likelihood of high frequency self-harm. Although some of the effects were small, particularly in relation to lifetime frequency of self-harm, overall our results suggest that experiential avoidance tendency may be an important psychological factor underpinning self-harm, regardless of suicidal intent (e.g. including mixed intent, suicidal intent, ambivalence), which is not accounted for in existing models of self-harm