Design, Development, and In-flight Testing of a Pointer/tracker for In-flight Experiments to Measure Aero-optical Effects over a Scaled Turret

We address the design, development, and testing of a pointer/tracker as a probe beam for the purpose of making high-speed, aero-optical measurements of the flow over a scaled beam director turret. The tracker uses retro-reflection of the probe beam off of a Reflexite annulus surrounding the turret. The constraints of the design required a near-total-commercial off the shelf system that could be quickly installed and removed in a rented aircraft. Baseline measurements of environmental vibrations are used to predict pointing performance; mitigation of line-of-sight jitter on the probe beam is achieved through passive isolation and the design of relay optics. Accommodation of ambient light is made with the use of wavelength filters and track algorithms. Postanalysis of measured data is compared to design estimates

Alterations in glutamatergic signaling contribute to the decline of circadian photoentrainment in aged mice

Robust physiological circadian rhythms form an integral part of well-being. The aging process has been found to negatively impact systems that drive circadian physiology, typically manifesting as symptoms associated with abnormal/disrupted sleeping patterns. Here, we investigated the age-related decline in light-driven circadian entrainment in male C57BL/6J mice. We compared light-driven resetting of circadian behavioral activity in young (1e2 months) and old (14e18 months) mice and explored alterations in the glutamatergic pathway at the level of the circadian pacemaker, the suprachiasmatic nucleus (SCN). Aged animals showed a significant reduction in sensitivity to behavioral phase resetting by light. We show that this change was through alterations in N-Methyl-D-aspartate (NMDA) signaling at the SCN, where NMDA, a glutamatergic agonist, was less potent in inducing clock resetting. Finally, we show that this shift in NMDA sensitivity was through the reduced SCN expression of this receptor’s NR2B subunit. Only in young animals did an NR2B antagonist attenuate behavioral resetting. These results can help target treatments that aim to improve both physiological and behavioral circadian entrainment in aged populations

Review of \u3ci\u3eTurtle’s Penguin Day\u3c/i\u3e by Valeri Gorbachev

https://digitalcommons.cedarville.edu/intern_book_reviews/1071/thumbnail.jp

Review of \u3ci\u3eAll Stations! Distress! April 15, 1912: The Day the Titanic Sank\u3c/i\u3e by Don Brown

https://digitalcommons.cedarville.edu/intern_book_reviews/1073/thumbnail.jp

Review of \u3ci\u3eNo Babysitters Allowed\u3c/i\u3e by Amber Stewart

https://digitalcommons.cedarville.edu/intern_book_reviews/1072/thumbnail.jp