Noise reduction in ECG signals for bio-telemetry

In Biotelemetry, Biomedical signal such as ECG is extremely important in the diagnosis of patients in remote location and is recorded commonly with noise. Considered attention is required for analysis of ECG signal to find the patho-physiology and status of patient. In this paper, LMS and RLS algorithm are implemented on adaptive FIR filter for reducing power line interference (50Hz) and (AWGN) noise on ECG signals .The ECG signals are randomly chosen from MIT_BIH data base and de-noising using algorithms. The peaks and heart rate of the ECG signal are estimated. The measurements are taken in terms of Signal Power, Noise Power and   Mean Square Error

ALDEHYDE EMISSIONS FROM TWO-STROKE AND FOUR-STROKE SPARK IGNITION ENGINES WITH CATALYTIC CONVERTER RUNING ON GASOHOL

Rad donosi rezultate ispitivanja emisije aldehida iz dvotaktnog i četverotaktnog jednocilindričnog motora na paljenje svjećicama koji koristi mješavinu benzina (80 vol. %) i alkohola (20 vol.); motor je prevučen bakrom (sloj debljine 300 μm na klipu i na unutarnjoj strani glave cilindra) i opremljen katalizatorom od spužvastog željeza. Rezultati su uspoređeni s konvencionalnim benzinskim motorom na paljenje svjećicama. Motor prevučen bakrom pokazuje smanjenje emisije aldehida u odnosu na konvencionalni motor za oba ispitna goriva. Katalitički pretvornik s ubrizgavanjem zraka značajno smanjuje štetne emisije kod oba ispitna goriva i kod obje konfiguracije motora.This paper reports aldehyde emissions from two-stroke and four-stroke, single cylinder spark ignition (SI) engines with gasohol (80 vol. % gasoline, 20 vol. % ethanol) having copper coated engine (copper-coated thickness, 300 μm) on piston crown and inner side of cylinder head) provided with catalytic converter with sponge iron as catalyst and compared with conventional SI engine with gasoline operation. Copper-coated engine showed reduction in aldehyde emissions when compared with conventional engine with both test fuels. Catalytic converter with air injection significantly reduced emissions with both test fuels on both configurations of the engine

Study of Gain Switching in Vertical Cavity Surface Emitting Laser under Different Electrical Pulse Inputs

Vertical cavity surface emitting laser (VCSEL) is a strong candidate for short pulse generation among the other semiconductor lasers in the era of laser technology. A 1550 nm, low power VCSEL is excited under different current shapes and the chief laser parameters are found out. The concept of gain switching under various current profiles are utilized effectively to bring out maximum laser power with minimum pulse width, which are the essential factors for long haul high speed optical data transmission. For a haversine electrical current input with 3.7 Ith amplitude, a laser peak power of 2.2 mW at 57 ps pulse width is obtained. In the case of trapezoidal pulse, 67 ps pulse width is obtained for 2.6 Ith current amplitude. It is also observed that square pulse of amplitude 2 Ith produces short optical pulse of 0.887 mW peak power and 89 ps width which shows the best performance when compared to other forms of pulses discussed in this work at the same input condition

Capping and mitogenesis: A model implicating microfilaments in lymphocyte activation

In lymphocytes cap formation induced by concanavalin A (con A) was found to be concentration dependent on the mitogen in the presence of colchicine, a microtubule disrupting agent. The dose-respone of cap formation under these conditions was similar to mitogen dose-response. In addition, a direct correlation was found between con A capping induced in the presence of colchicine and mitogenic responses with con A alone. Agents such as dibutyryl cyclic AMP, which suppress mitogenic responses, decrease capping. Zinc increases capping when it causes enhancement of mitogenesis and decreases capping when it suppresses mitogenic response. These observations are interpreted on the basis of a model in which binding of con A to surface receptors leads to formation of microfilaments, which might be essential for capping as well as the initiation of DNA synthesis. Thus, the experimental observations in this report lend support to a model implicating the formation of microfilaments as a crucial event in triggering a variety of cellular responses following ligand binding.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/23867/1/0000106.pd

Age-related differential effects of zinc on concanavalin A-induced capping of human lymphocytes

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24103/1/0000360.pd

Raman Spectroscopic Methods for Classification of Normal and Malignant Hypopharyngeal Tissues: An Exploratory Study

Laryngeal cancer is more common in males. The present study is aimed at exploration of potential of conventional Raman spectroscopy in classifying normal from a malignant laryngopharyngeal tissue. We have recorded Raman spectra of twenty tissues (aryepiglottic fold) using an in-house built Raman setup. The spectral features of mean malignant spectrum suggests abundance proteins whereas spectral features of mean normal spectrum indicate redundancy of lipids. PCA was employed as discriminating algorithm. Both, unsupervised and supervised modes of analysis as well as match/mismatch “limit test” methodology yielded clear classification among tissue types. The findings of this study demonstrate the efficacy of conventional Raman spectroscopy in classification of normal and malignant laryngopharyngeal tissues. A rigorous evaluation of the models with development of suitable fibreoptic probe may enable real-time Raman spectroscopic diagnosis of laryngopharyngeal cancers in future

Perceptions of undergraduate medical students of old traditional and new CBME curriculum about pharmacovigilance and adverse drug reactions reporting at a tertiary care teaching hospital: a comparative study

Background: National pharmacovigilance program is an ongoing program to monitor the adverse drug reactions and reporting at the earliest. The effectiveness and success of any pharmacovigilance system depends highly on the participation of all health care professionals. As medical students are future health-care givers, this study is aimed to measure perceptions on Pharmacovigilance and ADR reporting among medical students of two different curriculum. Methods: A validated and standardized KAP Questionnaire based cross sectional study. It consists of 22 questions divided into four sections of total of 22 items (six related to Personal details, eight related to knowledge, four related to attitude, and four related to practice) The filled questionnaires were collected and analyzed by MS excel Results: A comparative sample of 100 from old (phase 4) and 100 from New CBME (phase 3) curriculum undergraduate medical students of Government Medical College are included in our study. The average score of phase 3 and phase 4 medical students for knowledge was 85.37% and 75.87%, for attitude was 95.5% and 84% and for practices was 88.75% and 67.5% respectively. Conclusions: The overall knowledge, attitude and practices of new curriculum students found to be better than old curriculum students as CBME curriculum was introduced from the academic year 2019–2020 in all Medical Institutions of India to impart knowledge, communication and leadership skills using various teaching–learning methods among students

A HYBRID TECHNIQUE FOR PAPR REDUCTION OF OFDM USING DHT PRECODING WITH PIECEWISE LINEAR COMPANDING

Orthogonal Frequency Division Multiplexing (OFDM) is a fascinating approach for wireless communication applications which require huge amount of data rates. However, OFDM signal suffers from its large Peak-to-Average Power Ratio (PAPR), which results in significant distortion while passing through a nonlinear device, such as a transmitter high power amplifier (HPA). Due to this high PAPR, the complexity of HPA as well as DAC also increases. For the reduction of PAPR in OFDM many techniques are available. Among them companding is an attractive low complexity technique for the OFDM signal’s PAPR reduction. Recently, a piecewise linear companding technique is recommended aiming at minimizing companding distortion. In this paper, a collective piecewise linear companding approach with Discrete Hartley Transform (DHT) method is expected to reduce peak-to-average of OFDM to a great extent. Simulation results shows that this new proposed method obtains significant PAPR reduction while maintaining improved performance in the Bit Error Rate (BER) and Power Spectral Density (PSD) compared to piecewise linear companding method

Studies On 3/7 Caspase Activity And Apoptosis Induction By Diarylheptaniods Isolated From Garuga Pinnata Roxb

This study aims to evaluate the stimulation of caspase 3/7, 8 and 9 activity and induction of apoptosis by the diarylheptanoids isolated from Garuga pinnata (G. pinnata) RoxB. Garuganin 1, 3, 4 and 5 which were previously reported for their isolation have tested for their anticancer potencies by different caspase activation and apoptosis induction in MCF-7 and HCT-15 cell lines. However, based on the MTT assay results (Previously reported) Garuganin 3 and 5 were selected for this study.  from the stem bark of G. pinnata. The activation of caspases 3/7, 8, and 9 is a conformational process of cancer cell death. Such activation of caspases by different concentrations (05, 10, 15, 2