17 research outputs found
"Es ist keine Ferieninsel [...] aber auch kein Alcatraz". Inhaltsanalytische Betrachtungen zur Entlastungsfunktion von Schulinseln in der Schweiz. Qualitativ-empirische Ergebnisse im Rahmen einer explanativen Mixed-Methods-Studie
Der vorliegende Beitrag ermöglicht den Einblick in Ergebnisse der zweiten, qualitativ ausgerichteten Forschungsetappe des Projekts "Schulinseln in der Schweiz". Als Ergänzung und Erweiterung zu den quantitativen Ergebnissen kann gezeigt werden, dass Schulinseln nicht nur sehr verschiedenartig umgesetzt werden, sondern auch die Entlastungsfunktion von Schulinseln unterschiedliche Bedeutung haben kann. Abschließend werden vier Thesen präsentiert, die die qualitativen Resultate kritisch diskutieren und weiterführende Perspektiven auf dieses Forschungsfeld eröffnen. (DIPF/Orig.
A single preoperative FGF23 measurement is a strong predictor of outcome in patients undergoing elective cardiac surgery: a prospective observational study
VizieR Online Data Catalog: Third catalog of LAT-detected AGNs (3LAC) (Ackermann+, 2015)
Supplemental material related to the Fermi LAT third source catalog (3FGL) (Acero et al, 2015)The gamma-ray results used in this paper were derived in the context of the 3FGL catalog (Fermi-LAT Collaboration 2015, J/ApJS/218/23). No additional analysis of the gamma-ray data was performed in the context of the present paper except for the fitting of the monthly light curves and the broadband SED fitting. The data were collected over the first 48 months of the mission, from 2008 August 4 to 2012 July 31 (MJD 54682 to 56139). Using the Australia Telescope Compact Array (ATCA) at 5 GHz and 9 GHz, Petrov et al. (2013, J/MNRAS/432/1294) detected 424 sources in the LAT error ellipses of southern unassociated 2FGL sources. See table 2
Improving physical fitness and health status perception in community-dwelling older adults through a structured program for physical activity promotion in the city of Naples, Italy: A randomized controlled trial
Aim: To evaluate the efficacy and feasibility of a physical activity promotion intervention in community-dwelling older adults based on a free program of exercise adapted for older adults aged ≥60years managed by trainees from the Movement Sciences degree course. Methods: A total of 160 adults aged 60-82 years were randomly allocated into the intervention and control group. The exercise program consisted of 1-h sessions carried out twice a week for a year. Control participants received recommendations about an active lifestyle from their physicians. Senior Fitness Tests and the 12-item Short Form Health Survey were used to assess six functional fitness domains of participants and perception of their health status, respectively. Body mass index was also evaluated. Results: A total of 62 participants completed the exercise path. At the end of the intervention, they showed a significant body mass index decrease (from 27.9±1.6 to 25.1±1.8kg/m2, P0.05). A high acceptance of the intervention was registered among participants (>88.7%); staff competence and gratuitousness were the most appreciated features (>85.5%). Conclusions: The structured program represented a useful opportunity to promote physical activity among participants, and it was effective in improving their physical fitness and health status perception. Similar interventions are required to sensitize the whole older population, and experts in Movement Sciences might represent a key figure in this context. Geriatr Gerontol Int 2016; ••: ••-••
A single preoperative FGF23 measurement is a strong predictor of outcome in patients undergoing elective cardiac surgery: a prospective observational study
Abstract
Introduction
Several scoring systems have been developed to predict postoperative mortality and complications in patients undergoing cardiac surgery. However, these computer-based calculations are time- and cost-intensive. A simple but highly predictive test for postoperative risk would be of clinical benefit with respect to increasingly scarce hospital resources. We therefore assessed the predictive power of fibroblast growth factor 23 (FGF23) measurement compared with an established scoring system.
Methods
We conducted a prospective interdisciplinary observational study at the Saarland University Medical Centre that included 859 patients undergoing elective cardiac surgery between January 2010 and March 2011 with a median follow-up after discharge of 822Â days. We compared a single preoperative measurement of FGF23 as a prognostic tool with the 18 parameters comprising EuroSCORE II with respect to postoperative mortality, acute kidney injury, non-occlusive mesenteric ischemia, clinical course and long-term outcome.
Results
Preoperative FGF23 levels were highly predictive of postoperative outcome and complications. The predictive value of FGF23 for mortality in the receiver operating characteristic curve was greater than the EuroSCORE II (area under the curve: 0.800 versus 0.725). Moreover, preoperative FGF23 independently predicted postoperative acute kidney injury and non-occlusive mesenteric ischemia comparably to the EuroSCORE II. Finally, FGF23 was found to be an independent predictor of clinical course parameters, including duration of surgery, ventilation time and length of stay.
Conclusions
In patients undergoing elective cardiac surgery, a simple preoperative FGF23 measurement is a powerful indicator of surgical mortality, postoperative complications and long-term outcome. Its utility compares to the widely used EuroSCORE II.
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