The Barkhatny ultramafic-mafic massif (Kuznetsk Alatau Ridge, SW Siberia): structural and compositional evolutions of rocks

A complex of petrographic and petrofabric analyses that was carried out for rocks from an ultramafic-mafic massif of the Barkhatnaya Mountain in the Northern part of the Kuznetsk Alatau allowed us to prove that internal anisotropy of mineral aggregates had deformation-type evolution, which indicates possible plastic exhumation of lithosphere mantle fragments into upper crust levels. Additional mineralogical and geochemical researches of the basic component point out high possibility of multistage model for obduction of ophiolite association segments proposed for this region

Matter and physical anisotropy of ultramafites of the Barkhatny massif (Kuznetsk Alatau ridge, Western Siberia) as criteria of their mineral potential for geological prospecting works

A complex of petrographic, petrofabric, and paleomagnetic analyses that was carried out for rocks from an ultrabasic massif of the Barkhatnaya Mountain in the Northern part of the Kuznetsk Alatau allowed us to prove that internal anisotropy of mineral aggregates had deformation-type evolution, which indicates possible plastic exhumation of lithosphere mantle fragments into upper crust levels. Complete conformity of geophysical and petrofabric parameters points out high possibility of multistage model for obduction of ophiolite association segments proposed for this region. Taking into account specifics of minerageny for such complexes (chromite ores and noble metals, asbestos and nephrites), we offer a new technology for geological prospecting works at the stage of estimating mineral potential of such geological objects, which is based on the presence of differently oriented systems of mineral plane orientation.Проведенный нами комплекс структурно-петрологических и палеомагнитных исследований для ультрабазитов Бархатно- го массива на северном склоне Кузнецкого Алатау подтверждает, что внутренняя анизотропия минеральных агрегатов име- ла деформационную эволюцию, которая указывает на возможную пластическую эксгумацию фрагментов мантии литосферы в верхние горизонты земной коры. Полное соответствие геофизических и петроструктурных параметров отмечает высокую вероятность многостадийной обдукции фрагментов офиолитовой ассоциации, предлагаемой для этого региона. Принимая во внимание особенности минерагении (хромитовые руды и благородные металлы, асбест и нефрит) для таких комплексов мы предлагаем новые методы геологоразведочных работ на стадии оценки рудоносности геологических объектов, которые харак- теризуются дискретными вариациями пространственной ориентировки элементов текстурной анизотропии пород

Specifics of geological composition, geochemistry and geochronology of rocks from the Kresty alkaline-ultrabasic massif (Maimecha-Kotui province, Polar Siberia)

In this work, we demonstrate new data that allows us to accurate geochronological ranges of formation of the Kresty alkaline-ultrabasic massif, which is considered to be a satellite of the Gulinian giant pluton. We also interpreted geological, geochemical and isotope-geochemical data obtained earlier for major varieties of this volcanic-plutonic association taking into account new geochronological results, as well as considered new aspects/information on matter source of alkaline-ultrabasic massifs from this province. One of the main aspects is interaction of Siberian super plume matter with hosting substrate of Siberian craton continental crust

Clinical evaluation of effectiveness of new product of specialized sports nutrition for correction of psychophysiological state and neuromuscular transmission in highly qualified athletes

The purpose of the study is to determine the effectiveness of the specialized product Fit Tonus for correcting the psychophysiological state and neuromuscular transmission in highly qualified athletes.Materials and methods: the objects of research were: specialized product of sports nutrition for correcting the psychophysiological state and neuromuscular transmission Fit Tonus; 21 male martial arts athletes aged 14 to 25 years. The researches were carried out in accordance with official and conventional techniques. Body temperature, breathing rate, blood pressure level, heart rate was determined, heart rate variability, ECG, external breathing, O2 intake, total urine test, clinical blood test, biochemical blood indices were evaluated, water sectors of the body, body skinny weight, body fat weight were determined. Full-function cardiopulmonary analysis was performed using the Meta Lyzer 3B inpatient cardio-respiratory loading diagnostic system (Cortex Medical, Germany). Maximum oxygen consumption was determined by a Cosomed metabolograph (Italy). Biochemical parameters (bilirubin, ACT, ALT, urea, uric acid, glucose, cholesterol, HGT, amylase, alkaline phosphatase, creatinine) were examined on a Humalyzer biochemical analyzer. Water sectors of the body, the value of skinny body weight and fat body weight were determined on an analyzer for assessing the balance of water sectors of the body (Medass, Russia).Results: in the analysis of biochemical blood values, the blood levels of indicator enzymes and their isoforms were normalized in a short time, despite high training loads. This fact reflects the adaptation of the athlete’s body to high-intensity physical activity when taking the Fit Tone product. The obtained results of the increase in GUS, FFV and Tiffno test indicate an increase in both functional capabilities and functional abilities of the external breathing system, as well as an increase in the efficiency of the respiratory center in athletes who received the tested product. The effectiveness of the test product is confirmed by the results of dynamic and stress samples in a stabilometric study. Results of examination of psychophysical status of single wrestlers showed that during usage of developed product such indicators as performance, vegetative coefficient, dynamism, speed of movement, accuracy of actions, stability of actions are significantly increased. At the same time, the level of fatigue and anxiety is reliably reduced.Conclusions: the results of the researches performed showed that the product developed demonstrated efficacy for most of the parameters under research in the main group compared to the control (placebo)

Chronic Methamphetamine Administration Causes Differential Regulation of Transcription Factors in the Rat Midbrain

Methamphetamine (METH) is an addictive and neurotoxic psychostimulant widely abused in the USA and throughout the world. When administered in large doses, METH can cause depletion of striatal dopamine terminals, with preservation of midbrain dopaminergic neurons. Because alterations in the expression of transcription factors that regulate the development of dopaminergic neurons might be involved in protecting these neurons after toxic insults, we tested the possibility that their expression might be affected by toxic doses of METH in the adult brain. Male Sprague-Dawley rats pretreated with saline or increasing doses of METH were challenged with toxic doses of the drug and euthanized two weeks later. Animals that received toxic METH challenges showed decreases in dopamine levels and reductions in tyrosine hydroxylase protein concentration in the striatum. METH pretreatment protected against loss of striatal dopamine and tyrosine hydroxylase. In contrast, METH challenges caused decreases in dopamine transporters in both saline- and METH-pretreated animals. Interestingly, METH challenges elicited increases in dopamine transporter mRNA levels in the midbrain in the presence but not in the absence of METH pretreatment. Moreover, toxic METH doses caused decreases in the expression of the dopamine developmental factors, Shh, Lmx1b, and Nurr1, but not in the levels of Otx2 and Pitx3, in saline-pretreated rats. METH pretreatment followed by METH challenges also decreased Nurr1 but increased Otx2 and Pitx3 expression in the midbrain. These findings suggest that, in adult animals, toxic doses of METH can differentially influence the expression of transcription factors involved in the developmental regulation of dopamine neurons. The combined increases in Otx2 and Pitx3 expression after METH preconditioning might represent, in part, some of the mechanisms that served to protect against METH-induced striatal dopamine depletion observed after METH preconditioning

Clinical case: Marshall's syndrome

The article presents a clinical case of Marshall syndrome in a 5.5- year-old child. The key aspects of the clinical picture and differential diagnosis are described.В статье представлен клинический случай синдрома Маршалла у ребенка 5,5 лет. Описаны ключевые аспекты клинической картины и дифференциальной диагностики

Methamphetamine-Induced Dopamine-Independent Alterations in Striatal Gene Expression in the 6-Hydroxydopamine Hemiparkinsonian Rats

Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle are used extensively as a model of Parkinson's disease. The present experiments sought to identify genes that were affected in the dopamine (DA)–denervated striatum after 6-hydroxydopamine-induced destruction of the nigrostriatal dopaminergic pathway in the rat. We also examined whether a single injection of methamphetamine (METH) (2.5 mg/kg) known to cause changes in gene expression in the normally DA-innervated striatum could still influence striatal gene expression in the absence of DA. Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle resulted in METH-induced rotational behaviors ipsilateral to the lesioned side and total striatal DA depletion on the lesioned side. This injection also caused decrease in striatal serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels. DA depletion was associated with increases in 5-HIAA/5-HT ratios that were potentiated by the METH injection. Microarray analyses revealed changes (± 1.7-fold, p<0.025) in the expression of 67 genes on the lesioned side in comparison to the intact side of the saline-treated hemiparkinsonian animals. These include follistatin, neuromedin U, and tachykinin 2 which were up-regulated. METH administration caused increases in the expression of c-fos, Egr1, and Nor-1 on the intact side. On the DA-depleted side, METH administration also increased the expression of 61 genes including Pdgf-d and Cox-2. There were METH-induced changes in 16 genes that were common in the DA-innervated and DA-depleted sides. These include c-fos and Nor-1 which show greater changes on the normal DA side. Thus, the present study documents, for the first time, that METH mediated DA-independent changes in the levels of transcripts of several genes in the DA-denervated striatum. Our results also implicate 5-HT as a potential player in these METH-induced alterations in gene expression because the METH injection also caused significant increases in 5-HIAA/5-HT ratios on the DA-depleted side

Two-stage evolution of mantle peridotites from the Stalemate Fracture Zone, northwestern Pacific

This paper reports the results of a mineralogical study of 14 mantle peridotite samples dredged in 2009 from the eastern slope of the northwestern segment of the Stalemate Ridge in the northwestern Pacific during cruise SO201-KALMAR Leg 1b of the R/V Sonne. The sample collection included four serpentinized and silicified dunites and ten variably serpentinized lherzolites. The compositions of primary minerals (clinopyroxene, orthopyroxene, and spinel) change systematically from the lherzolites to dunites. Spinel from the lherzolites shows higher Mg# and lower Cr# values (0.65-0.68 and 0.26-0.33, respectively) compared with spinel from the dunites (Mg# = 0.56-0.64 and Cr# = 0.38-0.43). Clinopyroxene from the lherzolites is less magnesian (Mg# = 91.7-92.4) than clinopyroxene from dunite sample DR37-3 (Mg# = 93.7). Based on the obtained data, it was concluded that the lherzolites of the Stalemate Fracture Zone were derived by 10-12% near-fractional melting of a DMM-type depleted mantle reservoir beneath the Kula-Pacific spreading center. The dunites were produced by interaction of residual lherzolites with sodium- and titaniumrich melt and are probably fragments of a network of dunite channels in the shallow mantle. The moderately depleted composition of minerals clearly distinguishes the lherzolites from the strongly depleted peridotites of the East Pacific Rise and indicates the existence of slow-spreading mid-ocean ridges in the Pacific Ocean during the Cretaceous-Paleogene

Is Privacy Controllable?

One of the major views of privacy associates privacy with the control over information. This gives rise to the question how controllable privacy actually is. In this paper, we adapt certain formal methods of control theory and investigate the implications of a control theoretic analysis of privacy. We look at how control and feedback mechanisms have been studied in the privacy literature. Relying on the control theoretic framework, we develop a simplistic conceptual control model of privacy, formulate privacy controllability issues and suggest directions for possible research.Comment: The final publication will be available at Springer via http://dx.doi.org/ [in press

SMEAR Estonia : Perspectives of a large-scale forest ecosystem – Atmosphere research infrastructure

Non peer reviewe