Programa de educación médica a distancia: curso on line de Climaterio

Los programas médicos educativos a distancia constituyen hoy herramientas que permiten accesibilidad, comunicación fluida y mecanismos de gestión de la enseñanza y evaluación que responden a una creciente demanda de formación médica en todas las áreas de la salud. La modalidad “on line” es un instrumento más que conforma el proceso educativo y logra dos conceptos estrechamente ligados con la formación: a)la ubicuidad ( la formación siempre presente) y la holoconectividad (el campus siempre con nosotros) ,abriendo la posibilidad de acceder e involucrarse en el programa de actualización elegido.Facultad de Ciencias Médica

The technology-evoked time use rebound effect and its impact on pro-environmental consumer behaviour in tourism

The growing awareness of tourism’s environmental impacts has facilitated energy efficiency improvements in all tourism sub-sectors, especially in tourist transport. Further technological improvements are envisaged to save travel time as well as to reduce travel costs. However, the time savings achieved can potentially trigger behavioural responses of tourists that are unexpected and can intensify consumption. Ultimately, this intensified consumption can negate the positive effect of energy efficiency improvements in tourism, the phenomenon known as the time use rebound effect. Existing literature fails to account for this effect as a driver of unsustainable consumer behaviour in tourism. This paper proposes a framework to conceptualise the potential time use rebound effect in tourism and discusses the importance of considering it for better understanding and management of pro-environmental tourist behaviour. The paper elaborates upon the implications of the time use rebound effect for sustainable tourism development. Highlights Discusses the effect of energy efficiency improvements in tourism on consumption Demonstrates this effect is not always positive Conceptualises the rebound effect in tourism with respect to time Discusses how the time use rebound effect can reduce the positive effect of energy efficiency improvements in tourism

Thrittene, homologous with somatostatin-28(1-13), is a novel peptide in mammalian gut and circulation

Preprosomatostatin is a gene expressed ubiquitously among vertebrates, and at least two duplications of this gene have occurred during evolution. Somatostatin-28 (S-28) and somatostatin-14 (S-14), C-terminal products of prosomatostatin (ProS), are differentially expressed in mammalian neurons, D cells, and enterocytes. One pathway for the generation of S-14 entails the excision of Arg13-Lys14 in S-28, leading to equivalent amounts of S-28(1-12). Using an antiserum (F-4), directed to the N-terminal region of S-28 that does not react with S-28(1-12), we detected a peptide, in addition to S-28 and ProS, that was present in human plasma and in the intestinal tract of rats and monkeys. This F-4 reacting peptide was purified from monkey ileum; and its amino acid sequence, molecular mass, and chromatographic characteristics conformed to those of S-28(1-13), a peptide not described heretofore. When extracts of the small intestine were measured by RIA, there was a discordance in the ratio of peptides reacting with F-4 and those containing the C terminus of ProS, suggesting sites of synthesis for S-28(1-13) distinct from those for S-14 and S-28. This was supported by immunocytochemistry, wherein F-4 reactivity was localized in gastrointestinal (GI) endocrine cells and a widespread plexus of neurons within the wall of the distal gut while immunoreactivity to C-terminal domains of S-14 and S-28 in these neurons was absent. Further, F-4 immunoreactivity persisted in similar GI endocrine cells and myenteric neurons in mice with a targeted deletion of the preprosomatostatin gene. We believe that these data suggest a novel peptide produced in the mammalian gut, homologous with the 13 residues of the proximal region of S-28 but not derived from the Pros gene. Pending characterization of the gene from which this peptide is derived, its distribution, and function, we have designated this peptide as thrittene. Its localization in both GI endocrine cells and gut neurons suggests that thrittene may function as both a hormone and neurotransmitter.Fil: Ensinck, John W.. University of Washington; Estados UnidosFil: Baskin, Denis G.. University of Washington; Estados Unidos. Department of Veterans Affairs Puget Sound Health Care System; Estados UnidosFil: Vahl, Torsten P.. University of Cincinnati; Estados UnidosFil: Vogel, Robin E.. University of Washington; Estados UnidosFil: Laschansky, Ellen C.. University of Washington; Estados UnidosFil: Francis, Bruce H.. University of Washington; Estados UnidosFil: Hoffman, Ross C.. ZymoGenetics; Estados UnidosFil: Krakover, Jonathan D.. ZymoGenetics; Estados UnidosFil: Stamm, Michael R.. ZymoGenetics; Estados UnidosFil: Low, Malcolm J.. Oregon Health Sciences University; Estados UnidosFil: Rubinstein, Marcelo. Oregon Health Sciences University; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Otero Corchon, Veronica. Oregon Health Sciences University; Estados UnidosFil: D'Alessio, David A.. University of Cincinnati; Estados Unido

Exploring Foreign Tourists’ Image of Tanzania: A Factorial Analysis Approach

In the last decade, the economy of African continent and Tanzaniain particular has witnessed a business boom of the tourism sector.While the sector has continued to grow and become a dependablesource of direct and indirect employment to youths in urban andrural areas, the sector has been awash with challenges. Thesechallenges include terrorism attacks, energy crises and poor infrastructure.However, the impact of these challenges on the image of Tanzania as a tourist destination has not received the deserved attention. This study explores the perception of visitors towards Tanzania as a tourist destination after they have completed their tourist visit. This study employs factor analysis technique to explore country destination image. Questionnaires were administered tovisitors at some of the tourists’ hotels and Julius Kamabarage Nyerere International Airport (as a major exit point) in the country. Front line employees, various tourist sites and access to services emerged to be strong tourist destination image factors. This implies that the efforts of marketing tourism destination should focus on promoting all the sites the country has