326 research outputs found

    Early book sharing: What teachers should know

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    The purpose of this paper is to describe strategies that caregivers use while reading books with young children. Research indicates that caregivers: a) use strategies that simplify or extend book language, b) use prosody, and c) use management strategies so the book reading event is meaningful for children. Then, how teachers of preschool children can use these same strategies to plan meaningful book sharing events for children in preschool settings is described

    Student Choices: Book Selection Strategies of Fourth Graders

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    In many literature-based reading programs, students are encouraged to self-select their own reading materials. However, self-selection causes apprehensions for many teachers. They are concerned not only about their students\u27 ability to select books that are appropriate for their reading level but they are also concerned about the types of books the students may choose. Consequently many teachers may decide to use anthologies or whole class texts where they maintain some control over the students\u27 reading material. However, student interest and student choice should be an integral part of an elementary reading program if students are going to beturned onto reading (Rasinski, 1988) and become lifelong readers

    Bayesian space-time analysis of health insurance data

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    Generalized linear models (GLMs) and semiparametric extensions provide a flexible framework for analyzing the claims process in non-life insurance. Currently, most applications are still based on traditional GLMs, where covariate effects are modelled in form of a linear predictor. However, these models may already be too restrictive if nonlinear effects of metrical covariates are present. Moreover, although data are often collected within longer time periods and come from different geographical regions, effects of space and time are usually totally neglected. We provide a Bayesian semiparametric approach, which allows to simultaneously incorporate effects of space, time and further covariates within a joint model. The method is applied to analyze costs of hospital treatment and accommodation for a large data set from a German health insurance company

    GABA-Transporter

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    Professional Development and Educational Policy: A Comparison of Two Fields in Education

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    The purpose of this paper is to compare two fields of research related to school reform: professional development and educational policy. A content analysis of the literature in both fields revealed two areas where they align (i.e., a focus on teachers’ professional development and the idea that change takes time) as well as two areas where there are differences (i.e., theoretical grounding of each field and planning for teachers’ learning). Considerations for successful school reform are suggested

    Transforming Schools: The Power of Teachers’ Input in Professional Development

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    Recent legislative actions have mandated the professional development of teachers in hopes of improved student achievement. However, research has shown that mandated professional development most usually does not lead to a positive outcome. This article describes three aspects that have been identified as contributing to the transformation of instruction in schools: school context, role of the administrator, and cohesion between professional development and needs of students/teachers. Mezirow’s adult learning theory supports these important aspects of school reform and has implications for planning and developing educators’ professional development

    A Subtle Interplay Between Three Pex11 Proteins Shapes De Novo Formation and Fission of Peroxisomes

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    The organization of eukaryotic cells into membrane-bound compartments must be faithfully sustained for survival of the cell. A subtle equilibrium exists between the degradation and the proliferation of organelles. Commonly, proliferation is initiated by a membrane remodeling process. Here, we dissect the function of proteins driving organelle proliferation in the particular case of peroxisomes. These organelles are formed either through a growth and division process from existing peroxisomes or de novo from the endoplasmic reticulum (ER). Among the proteins involved in the biogenesis of peroxisomes, peroxins, members of the Pex11 protein family participate in peroxisomal membrane alterations. In the yeast Saccharomyces cerevisiae, the Pex11 family consists of three proteins, Pex11p, Pex25p and Pex27p. Here we demonstrate that yeast mutants lacking peroxisomes require the presence of Pex25p to regenerate this organelle de novo. We also provide evidence showing that Pex27p inhibits peroxisomal function and illustrate that Pex25p initiates elongation of the peroxisomal membrane. Our data establish that although structurally conserved each of the three Pex11 protein family members plays a distinct role. While ScPex11p promotes the proliferation of peroxisomes already present in the cell, ScPex25p initiates remodeling at the peroxisomal membrane and ScPex27p acts to counter this activity. In addition, we reveal that ScPex25p acts in concert with Pex3p in the initiation of de novo peroxisome biogenesis from the ER

    Early detection of grapevine graft incompatibility: insights into translocated and virus-induced incompatibility

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    In vineyards to control phylloxera (Daktulosphaira vitifolia Ficth) attacks in Vitis vinifera L., heterografted vines are planted using American vines hybrids as rootstocks. However, graft incompatibilities can affect grape yield and plant longevity. Thus, to identify early graft incompatibility factors, we established in vitro micrografting protocols coupled with histology and histochemistry analysis in grapevine graft combinations of known compatibility behavior. The histochemical characterization of the graft union revealed irregular cell arrangement, slower vascular differentiation, persistence of the necrotic layer, accumulation of starch, and lower differentiation of phloem cells in hetero- compared to homografts, indicating the presence of translocated incompatibility symptoms. We highlight the utility of evaluating the graft interface cellular arrangement and starch content via calcofluor and I2KI staining, respectively, as allowed to identify the graft combinations with lower graft success. Wounded and grafted Syrah plantlets pointed out an impaired sucrose distribution in these plants and levels of Grapevine Rupestris Stem Pitting associated Virus (GRSPaV) infections correlated with graft (un)-success in two Syrah clones micrografted onto 110-Ritcher rootstock. Furthermore, silencing GRSPaV before grafting increased graft success rates. We propose that grapevine graft incompatibility is mainly a virus-induced phenomenon that can arise even in certified plants

    Two-Dimensional Patterning by a Trapping/Depletion Mechanism: The Role of TTG1 and GL3 in Arabidopsis Trichome Formation

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    Trichome patterning in Arabidopsis serves as a model system to study how single cells are selected within a field of initially equivalent cells. Current models explain this pattern by an activator–inhibitor feedback loop. Here, we report that also a newly discovered mechanism is involved by which patterning is governed by the removal of the trichome-promoting factor TRANSPARENT TESTA GLABRA1 (TTG1) from non-trichome cells. We demonstrate by clonal analysis and misexpression studies that Arabidopsis TTG1 can act non-cell-autonomously and by microinjection experiments that TTG1 protein moves between cells. While TTG1 is expressed ubiquitously, TTG1–YFP protein accumulates in trichomes and is depleted in the surrounding cells. TTG1–YFP depletion depends on GLABRA3 (GL3), suggesting that the depletion is governed by a trapping mechanism. To study the potential of the observed trapping/depletion mechanism, we formulated a mathematical model enabling us to evaluate the relevance of each parameter and to identify parameters explaining the paradoxical genetic finding that strong ttg1 alleles are glabrous, while weak alleles exhibit trichome clusters
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