4,588 research outputs found
Big Bang Nucleosynthesis and the Missing Hydrogen Mass in the Universe
It is proposed that when the era of the big-bang nucleosynthesis ended,
almost all of the 75 percent of the observed total baryonic matter remained in
the form of hydrogen and continued to exist in the form of protons and
electrons. They are present today as baryonic dark matter in the form of
intergalactic hydrogen plasma. To test our hypothesis we have investigated the
effects of Thomson scattering by free electrons on the reported dimming of Type
Ia supernovae. The quantitative results of our calculation suggest that the
dimming of these supernovae, which are dimmer than expected and hence more
distant than predicted by Hubble expansion, is a result of Thomson scattering
without cosmic acceleration.Comment: A typographical error in equation (7) page 3 has been correcte
Non-destructive Neutron Activation Analysis of Aluminium and Phosphorus in Bone Biopsies
Peer Reviewe
Quantitative modeling of the molecular steps underlying shut-off of rhodopsin activity in rod phototransduction
PURPOSE: To examine the predictions of alternative models for the stochastic shut-off of activated rhodopsin (R*) and their implications for the interpretation of experimentally recorded single-photon responses (SPRs) in mammalian rods.
THEORY: We analyze the transitions that an activated R* molecule undergoes as a result of successive phosphorylation steps and arrestin binding. We consider certain simplifying cases for the relative magnitudes of the reaction rate constants and derive the probability distributions for the time to arrestin binding. In addition to the conventional model in which R* catalytic activity declines in a graded manner with successive phosphorylations, we analyze two cases in which the activity is assumed to occur not via multiple small steps upon each phosphorylation but via a single large step. We refer to these latter two cases as the binary R* shut-off and three-state R* shut-off models.
METHODS: We simulate R*âs stochastic reactions numerically for the three models. In the simplifying cases for the ratio of rate constants in the binary and three-state models, we show that the probability distribution of the time to arrestin binding is accurately predicted. To simulate SPRs, we then integrate the differential equations for the downstream reactions using a standard model of the rod outer segment that includes longitudinal diffusion of cGMP and CaÂČâș.
RESULTS: Our simulations of SPRs in the conventional model of graded shut-off of R* conform closely to the simulations in a recent study. However, the gain factor required to account for the observed mean SPR amplitude is higher than can be accounted for from biochemical experiments. In addition, a substantial minority of the simulated SPRs exhibit features that have not been reported in published experiments. Our simulations of SPRs using the model of binary R* shut-off appear to conform closely to experimental results for wild type (WT) mouse rods, and the required gain factor conforms to biochemical expectations. However, for the arrestin knockout (Arrâ/â) phenotype, the predictions deviated from experimental findings and led us to invoke a low-activity state that R* enters before arrestin binding. Our simulations of this three-state R* shut-off model are very similar to those of the binary model in the WT case but are preferred because they appear to accurately predict the mean SPRs for four mutant phenotypes, Arr+/â, Arrâ/â, GRK1+/â, and GRK1â/â, in addition to the WT phenotype. When we additionally treated the formation and shut-off of activated phosphodiesterase (E*) as stochastic, the simulated SPRs appeared even more similar to real SPRs, and there was very little change in the ensemble mean and standard deviation or in the amplitude distribution.
CONCLUSIONS: We conclude that the conventional model of graded reduction in R* activity through successive phosphorylation steps appears to be inconsistent with experimental results. Instead, we find that two variants of a model in which R* activity initially remains high and then declines abruptly after several phosphorylation steps appears capable of providing a better description of experimentally measured SPRs.This work was supported by award number R01EY023603 from the US National Eye Institute
Hysteresis in the Mott Transition between Plasma and Insulating Gas
We show that hysteresis can occur in the transition between a neutral plasma
and the insulating gas consisting of neutral pairs bound by Coulomb attraction.
Since the transition depends sensitively on the screening length in the plasma,
regions of bistability occur in density--temperature phase space. We present
numerical results which indicate where these regions occur for systems such as
spin-polarized hydrogen, positronium gas, and excitons in a semiconductor.Comment: 9 pages (Latex/RevTex), 6 postscript figures which are in compressed
and uuencoded file, prepared using the utility "uufiles" and separately
submitted. They should be automatically included with the text when it is
downloaded. Figures also available in hard copy from the authors
([email protected]; [email protected]); paper submitted to
Phys. Rev.
Cohomology of the minimal nilpotent orbit
We compute the integral cohomology of the minimal non-trivial nilpotent orbit
in a complex simple (or quasi-simple) Lie algebra. We find by a uniform
approach that the middle cohomology group is isomorphic to the fundamental
group of the sub-root system generated by the long simple roots. The modulo
reduction of the Springer correspondent representation involves the sign
representation exactly when divides the order of this cohomology group.
The primes dividing the torsion of the rest of the cohomology are bad primes.Comment: 29 pages, v2 : Leray-Serre spectral sequence replaced by Gysin
sequence only, corrected typo
Polarizations and Nullcone of Representations of Reductive Groups
The paper starts with the following simple observation. Let V be a representation of a reductive group G, and let f_1,f_2,...,f_n be homogeneous invariant functions. Then the polarizations of f_1,f_2,...,f_n define the nullcone of k 0} h(t) x = 0 for all x in L. This is then applied to many examples. A surprising result is about the group SL(2,C) where almost all representations V have the property that all linear subspaces of the nullcone are annihilated. Again, this has interesting applications to the invariants on several copies. Another result concerns the n-qubits which appear in quantum computing. This is the representation of a product of n copies of on the n-fold tensor product C^2 otimes C^2 otimes ... otimes C^2. Here we show just the opposite, namely that the polarizations never define the nullcone of several copies if n <= 3. (An earlier version of this paper, distributed in 2002, was split into two parts; the first part with the title ``On the nullcone of representations of reductive groups'' is published in Pacific J. Math. {bf 224} (2006), 119--140.
The Early Palomar Program (1950-1955) for the Discovery of Classical Novae in M81: Analysis of the Spatial Distribution, Magnitude Distribution, and Distance Suggestion
Data obtained in the 1950-1955 Palomar campaign for the discovery of
classical novae in M81 are set out in detail. Positions and apparent B
magnitudes are listed for the 23 novae that were found. There is modest
evidence that the spatial distribution of the novae does not track the B
brightness distribution of either the total light or the light beyond an
isophotal radius that is 70\arcsec from the center of M81. The nova
distribution is more extended than the aforementioned light, with a significant
fraction of the sample appearing in the outer disk/spiral arm region. We
suggest that many (perhaps a majority) of the M81 novae that are observed at
any given epoch (compared with say years ago) are daughters of
Population I interacting binaries. The conclusion that the present day novae
are drawn from two population groups, one from low mass white dwarf secondaries
of close binaries identified with the bulge/thick disk population, and the
other from massive white dwarf secondaries identified with the outer thin
disk/spiral arm population, is discussed. We conclude that the M81 data are
consistent with the two population division as argued previously from (1) the
observational studies on other grounds by Della Valle et al. (1992, 1994),
Della Valle & Livio (1998), and Shafter et al. (1996) of nearby galaxies, (2)
the Hatano et al. (1997a,b) Monte Carlo simulations of novae in M31 and in the
Galaxy, and (3) the Yungelson et al. (1997) population synthesis modeling of
nova binaries. Two different methods of using M81 novae as distance indicators
give a nova distance modulus for M81 as , consistent with the
Cepheid modulus that is the same value.Comment: 24 pages, 7 figures, accepted to PAS
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