Relationship Between Attrition Faces and Signs of TMD

Smatra se da su brusne fasete znak funkcijskih i parafunkcijskih aktivnosti, te ih nalazimo na okluzalnim i incizalnim plohama zuba obično kao posljedicu procesa atricije. Brusne fasete razlikuju se opsegom i pozicijom na zubima. Bruksizam, kao parafunkcijska aktivnost, smatra se jednim od etioloških čimbenika za nastanak disfunkcije stomatognatoga sustava. Cilj rada bio je istražiti moguću povezanost između pojavnosti brusnih faseta, kao znak bruksizma, i znakova temporomandibularne disfunkcije. Temeljem nalaza brusnih faseta nakon izvršena kliničkog pregleda izdvojeno je 100 ispitanika, određenih za daljnje istraživanje. Opsežnost brusnih faseta procjenjivana je modificiranim indeksom Pullingera i Seligmana: stupanj 0 = nema vidljive atricije; 1 = minimalna atricija kvržica ili incizalnih bridova (u caklini); 2 = fasete usporedne s normalnim područjima kontura ploha (caklina); 3 = zamjetna zaravnjenja kvržica ili incizalnih bridova (caklina); 4 = potpuni gubitak kontura ploha/bridova i ekspozicija dentina do polovice visine nekadašnje krune zuba; 5 = potpuni gubitak kontura i ekspozicija dentina za više od polovice nekadašnje krune zuba. Svi ispitanici podvrgnuti su kliničkim ispitivanjima kako bi se utvrdilo postojanja znakova TMD-a. Rezultati su pokazali da ne postoji statistički znatna povezanost između znakova TMD-a i pojavnosti brusnih faseta te ni između znakova TMD-a i opsežnosti brusnih faseta. Rezultati ovoga istraživanja slažu se s ostalim recentnim studijama da brusne fasete nisu pouzdan pokazatelj za procjenjvanje funkcijskog stanja stomatognatoga sustava. Ovim istraživanjem nije utvrđeno postojanje povezanosti između pojavnosti brusnih faseta i znakova temporomandibularne disfunkcije.Attrition faces are usually seen on the occlusal or incisal surfaces of teeth worn by attrition. They are considered to be a sign of functional and parafunctional activities, and can differ by wideness and position on the teeth. Bruxizm, as a parafunctional activity, is considered to be a risk factor for dysfunction of the masticatory system. The aim of the study was to investigate the possible relationship between attritional faces, as a sign of bruxizm, and signs of temporomandibular dysfunction. By clinical examination, a group of 100 subjects was selected for trial, based on findings of attritional faces. The severity of attrition faces was quantified on a fivepoint scale ( modified assessment for determination of incisal tooth wear according to Pullinger and Seligman: 0 = no visible tooth wear; 1 = minimal wear of cusps or incisal tips (enamel); 2 = faces parallel to normal planes of contour (enamel); 3 = noticeable flattening of cusp or incisal edges (enamel); 4 = total loss of contour and dental exposure when identifiable (dentin exposure up to half of former crown of tooth): 5 = total loss of contour and dental exposure over half of former crown of tooth). Selected subjects were then examined by standard procedure to investigate the presence of TMD signs. Results showed that there was no statistical significance between signs of TMD and presence of attrition faces, and neither between signs of TMD and severity of attrition faces. Results of this study are compatible with other recent investigations, which show that attrition faces are not a reliable sign for assessing the functional status of the masticatory system. According to this investigation there is no association between attrition faces and signs of temporomandibular dysfunction

Kineziographic Research of Patients with Cross Bite

The paper describes the use of an objective method for the quantitative analysis of the relationship between the posterior cross-bite and the occurrence of occlusive interferences and damages to the mandible muscle elevator. Two groups of subjects were selected for the analysis: 10 patients with unilateral cross-bite and 10 students without any symptoms of temporomandibular disorders (TMD). By means of the Robert Jenkelson K5A kinesiograph we measured maximal – opening velocity of the mandible (mm/s), maximal- closing velocity (mm/s), first tooth contact velocity and displacement in the vertical plane at the maximal intercuspidation (mm). The following values were obtained: maximal-opening velocity in the first group was 349 mm/s and 380 mm/s in the control group. This difference was incidental. The maximal closing velocity in the study group was 204.9 and 345.2 in the control group (p < 0.05). The first tooth contact velocity in the study group was 75.93 and 325 in the control group (p < 0.01). Displacements in the vertical plane at the maximal intercuspidation in the investigated group was 0.240.01 mm, while in control group that value was 0120.012 mm

Organizational readiness for co-creation of public services in the central and eastern european administrative tradition: Development of the conceptual multi-attribute decision support model

Co-creation of public services and policies is considered a promising practice of re-shaping the traditional relationship between the state and its citizens, businesses and non-governmental organizations (NGOs). Nevertheless, there are also warnings that the implementation of the process of co-creation could fail. A possible reason is that the organization is not ready or sufficiently mature to implement the process of co-creation. This paper addresses co-creation drivers and barriers identified through systematic literature review and analysis of case studies from two Central and Eastern European (CEE) countries. The aim of this paper is to provide practitioners from CEE countries with a conceptual multi-attribute decision support model for evaluating the organizational readiness for co-creation. The methodological framework consists of three steps. The first two steps, content analysis (i.e. literature review) and case-study analysis, were used to identify and analyze drivers and barriers, which are then used in the last step to develop the conceptual multi-attribute decision support model. The developed model consists of 26 attributes grouped into three categories: Capacity of the organization, drivers and barriers related to internal (public organization) co-creators, and context related drivers and barriers. The key points for practitioners are: •Co-creation drivers and barriers affect organizations at the beginning of their co-creation journey (i.e. in identifying the key co-creation success factor at the organizational level); •Co-creation drivers and barriers serve as guidance to organizations that were unsuccessful in co-creation; •The conceptual model supporting the evaluation of co-creation readiness serves as a tool to those that consider implementing co-creation; •The model offers an insight into a possible methodology for evaluation of readiness in different areas; •For practitioners from the CEE region, co-creation drivers and barriers, together with the conceptual multi-attribute decision support model supporting the evaluation of co-creation readiness, offer a roadmap to successful co-creation

Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase

Inhibitory effect of 32 coumarin derivatives (20 Schiff bases, 5 thiosemicarbazides, 5 thiazolidinones, and their precursors, 7-hydroxy-4-methylcoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate) on partially purified apple polyphenol oxidase was investigated. Thirteen coumarin derivatives inhibited polyphenol oxidase (5 Schiff bases, 5 thiosemicarbazides, 1 thiazolidinone, 4-methyl-7-hydroxycoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate), while 19 derivatives showed no effect on enzyme activity. The most effective inhibitors were thiosemicarbazides, with 4-methyl-1-(2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetyl) thiosemicarbazide (compound C23) being the most prominent inhibitor (IC50 = 10.45 µM). The importance of thiosemicarbazide moiety as crucial structure element for strong apple PPO inhibition was confirmed by its cyclisation to thiazolidinone bearing the same substituents as corresponding thiosemicarbazide. Capture of the sulphur atom of thiosemicarbazide group within tiazolidinone ring caused significant loss of inhibitory effect against apple PPO

Aflatoxin contamination of maize vended in Ondo state, Nigeria, and health risk assessment

Aflatoxin contamination of maize is a serious food safety problem worldwide. Despite the widespread consumption of maize in Nigeria, there is limited data on aflatoxin contents of maize vended in open markets in Ondo state, Nigeria. A total of 140 maize samples randomly purchased from major markets in four locations in Ondo state, were screened for total aflatoxins using an ELISA method. Exposure and health risk assessments were performed for the maize consumers by the deterministic and Margin of exposure (MOE) approaches, respectively. About 99% of the maize were contaminated with total aflatoxins (range: 0.65–265 µg/kg; mean: 125.9 µg/kg). Aflatoxin levels exceeding the 4 µg/kg set by the European Union for total aflatoxins were found in 88% of the maize whilst more than one half contained at least 100 µg/kg aflatoxins. The average probable daily intake values were 830, 332 and 138 ng/kg bw/day for the average children, adolescent and adult populations, respectively. Consequently, MOEs for the respective populations were 0.20, 0.51 and 1.23, suggesting a high level of health risk for consumers of maize vended in open markets in Ondo state due to high aflatoxin levels. Maize farmers and households in Ondo state need urgent aflatoxin mitigation interventions

Influence of Smoking on the Stomatognathic System in Women With Diabetes

Šećerna je bolest metabolička bolest koja nastaje kao posljedica poremećaja u stvaranju i lučenju inzulina ili njegovu djelovanju. Kod tako oslabljena organizma pušenje duhana vjerojatno više oštećuje stomatognati sustav nego u zdravih osoba. Žene s potvrđenom dijagnozom šećerne bolesti (N = 90) podijeljene su u dvije skupine: žene fertilne dobi (N = 51) te žene u menopauzi i postmenopauzi (N = 39). Sve su žene ispunile anketni list s općim podatcima i pitanjem o pušenju. Izvršen je klinički pregled s pomoću stomatološkoga zrcala i parodontne sonde. Vrjednovan je klinički nalaz zubnoga statusa, gingive i parodonta (indeks krvarećeg sulkusa i dubina parodontnih džepova) te stanje oralne sluznice. Pušenje nije statistički znatno utjecalo na zubni status ni u fertilnih žena ni u žena u menopauzi i postmenopauzi. (p > 0,05). Klinički nalaz gingive i parodonta statistički se znatno razlikovao samo u žena u menopauzi i postmenopauzi (*p 0,05). Klinički nalaz oralne sluznice analiziran je samo u dobnoj skupini menopauza i postmenopauza. Razlika je bila statistički znatna (*p < 0,05). U skupini fertilnih žena raščlamba nije izvršena zbog premalog broja podataka. Oslabljeni imunološki sustav zbog zajedničkoga djelovanja šećerne bolesti, pušenja i nedostatka ženskih spolnih hormona (u menopauzi i postmenopauzi) znatno oštećuje oralnu sluznicu, gingivu i parodont. Vjerojatni razlog tomu je njihova čvrsta povezanost osobito hematogenim putem s ostalim dijelovima organizma. Pušenje nije znatno utjecalo na tvrda zubna tkiva vjerojatno zbog njihove anorganske naravi i kompaktnosti građe.The aim of the study was to check the influence of smoking on the stomatognathic system in women with diabetes. Diabetes is metabolic disease that occurs as a result of disorders in creation or secretion of insulin, or its effect. On a weakened organism smoking will probably do more harm on the stomatognathic system then on a healthy one. Women with confirmed diagnosis of diabetes (N = 90) were divided into 2 groups: fertile women (N = 51) and women in the menopause and postmenopause (N = 39). All women completed the given paper forms on general data and their smoking habits. A clinical examination was performed using a stomatological mirror and parodontal probe. Clinical findings of the dental status, gingiva, parodontal tissue (bleeding sulcus index and depth of parodontal pockets) and the status of oral muscosa were evalued. Smoking did not show statistically significant influence on the dental status either on fertile women or on women in the menopause and postmenopause (p > 0.05). Clinical findings of the gingiva and parodontal tissue showed statistically significant difference in women in the menopause and postmenopause (*p 0.05). Clinical findings of oral muscosa were only analyzed in the age group of menopausal and postmenopausal women. The difference was statistically significant (*p < 0.05). In the group of fertile women analysis was not performed due to the small number of specimens. Weakened immunological system due to the synergistic influence of diabetes, smoking and the lack of feminine sex hormones (in the menopause and postmenopause) significantly damages oral muscosa, gingiva and parodontal tissue. The probable explanation was their firm correlation especially throughtout the blood circulation with the other parts of the organism. Smoking did not significantly influence the hard dental tissue, probably because of its inorganic origin and compact structure

Anterior Tooth Relationship in Cuspid Protected and Group Function Occlusion

OBJECTIVE OF INVESTIGATION: The aim of the study was to determine anterior tooth relationship (overbite and overjet) according to the type of occlusion (canine guided, group function). METHODS: A total of 111 test subjects (56 men and 55 women, mean 23.9 years of age) were examined, and it was determined that they have occlusional conception. The relationship of the front teeth in the position of maximum intercuspidation was evaluated by a portable meter. RESULTS: By analysing the obtained results of vertical overjet and horizontal overbite of the front teeth, we concluded that there was significant statistic difference in the amount of the vertical overjet with regard to occlusional conception (t=6.669, p=0.00001). Average value of the vertical overjet in examinees with occlusion lead by the canine was 2.22+0.09 mm, while in examinees with group function it was 1.58+0.26 mm. No significant statistical difference was found by analysing vertical overjet with regard to gender. No significant statistical difference between the groups was found by comparing the results of horizontal overbite of frontal teeth with regard to occlusional concepcion and gender. Average value of horizontal overjet was 1.62+0.29 mm. CONCLUSION: Subjects with canine guided occlusion have significantly and statistically bigger overjet of frontal teeth