437 research outputs found

    Modern interactive technologies of professional self-determination under the conditions of overcoming conflicting realities

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    The urgency of the problem under study is due to the fact that the professional life of a person under current conditions is highly dynamic; moreover, the attitude to the profession, the meaning of work, and its results is changing. The purpose of this article is to develop innovative psychological and pedagogical support of the professional self-determination of young students as well as to design an innovative psychological and educational technology of the professional choice promotion of an individual. The leading approach to the study of this problem is the psychological and pedagogical observation and questionnaires, which allow for the identification and the study of the experience in the field of development and application of interactive technologies of the provision of professional self-determination of the youth under the conditions of overcoming conflicting realities. This article presents conceptual provisions of interactive psychological and pedagogical support of professional self-determination of an individual in terms of continuing education as a semantic factor of the professional self-determination of an individual; defines goals, objectives, and principles of the modern interactive technology of psychological and pedagogical support of professional self-determination of the youth under the conditions of overcoming conflicting realities; and reveals an interactive technology for the provision of the professional self-determination of the youth. The article may be useful for psychologists, education psychologists, or career psychologists who are ready to use the Internet in order to facilitate an individual in its professional self-determination β€” namely, the creation of profession interactive services whose activity is not limited to the search for β€œthe most suitable profession”. Β© 2016 Hasanova, Kotova and Kandrashina

    Investment development of Russian regions backed up by natural monopolies

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    The article considers the issues of the relationship between business investment activities and the economic and social development of the regions. Based on the statistical data analysis it is shown that the decrease in investment activities negatively affects all key indicators of regional development after a short period of time. The article shows that a peculiarity defining Russian economy is that its significant part is actually controlled by natural monopolies. At the same time, they are strongly sensitive to all the problems of socioeconomic development of the country's territories and, therefore, are parties concerned in ensuring sustainable and qualitative growth of regional economies. Today many of the natural monopolies implement large-scale investment programs with allocated substantial resources. The analysis of these investment programs showed that they all contain components that contribute to the development of the region where the manufacturing facilities or transportation capacities of these companies are located. It is concluded that a systemic state investment policy aimed at stimulating real investments, rather than "portfolio" ones, is required to address the problem of sustainable economic growth.peer-reviewe

    Low molecular weight thymic factor inhibits histamine release from basophils

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    Low molecular weight thymic factor stimulates the suppressor function of T-lymphocytes, increases cAMP content (but not cGMP) in lymphocytes and inhibits histamine release from sensitized basophils. The mechanisms of LTF action are discussed

    Phase Filters for 3D Localization of Point Light Sources

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    The work relates to the engineering and research of phase filters for three-dimensional localization of point light emitters. These phase filters form a light field having two clearly visible maxima in their intensity distribution (i.e. two-lobe fields). By means of numerical simulation, the influence of the amplitude and phase distortions of the wave front of the illuminating beam on the two-lobe field formation has been studied in the work. Keywords: spiral light beams, amplitude distortions, phase distortions, threedimensional localization, two-lobe field

    A Modern View of Anomalies in the Metal Groups of the Periodic System of D.I.Mendeleev

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    The article is devoted to the 150th anniversary of the Periodic Table of Chemical Elements by D.I.Mendeleev. The fundamental law of nature, discovered by D.I.Mendeleev has anomalies and paradoxes associated with certain groups of metals. When studying the physical and chemical properties of complex metal compounds, many discrepancies can be found, namely, the location of elements in groups, which primarily relate to metals with different valences. By studying the approaches and methods for predicting the arrangement of chemical elements, it can be established that D.I.Mendeleev eliminated many differences for some metals during the formation of the Periodic system of chemical elements. D.I.Mendeleev developed a principle that excludes such errors when finding and discovering new elements. Analytical studies conducted by a Russian scientist helped to calculate the atomic masses and describe the properties of three elements not known at that time – Β«eka-boronΒ», Β«eka-siliconΒ», Β«eka-aluminumΒ», the existence of which was proved and confirmed by subsequent discoveries of scandium, germanium, boron, and gallium. The paper provides a significant assessment of the forecasting of metals in various groups of the periodic system. Changes in the properties of some metals significantly influenced their location in the table of D.I.Mendeleev

    Assessment of adherence of the population of Nizhny Tagil to comprehensive prevention of tick-borne diseases

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    The article presents the results of assessing public awarenessof comprehensive prevention of tick-borne diseases in the city of Nizhny Tagil, Sverdlovsk Region. Findings of a sociological questionnaire-based survey conducted during the period of the seasonal rise in tick activity served as the basis for improving health risk mitigation measuresΠ’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ ΠΏΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΎΡ†Π΅Π½ΠΊΠΈ информированности насСлСния Π³ΠΎΡ€ΠΎΠ΄Π° НиТнСго Π’Π°Π³ΠΈΠ»Π° ΠΏΠΎ вопросам комплСксной ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΠΊΠΈ ΠΊΠ»Π΅Ρ‰Π΅Π²Ρ‹Ρ… ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΉ. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ социологичСского опроса, ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ сСзонного подъСма активности ΠΊΠ»Π΅Ρ‰Π΅ΠΉ, явились основой ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΡ мСроприятий ΠΏΠΎ сниТСнию рисков для Π·Π΄ΠΎΡ€ΠΎΠ²ΡŒ

    ВивчСння Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΡ… Ρ€Π΅Ρ‡ΠΎΠ²ΠΈΠ½ Ρƒ Ρ‚Ρ€Π°Π²Ρ– ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ— ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Ρ‚ΠΎΠ½ΠΊΠΎΡˆΠ°Ρ€ΠΎΠ²ΠΎΡ— Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„Ρ–Ρ— Ρ‚Π° високоСфСктивної Ρ€Ρ–Π΄ΠΈΠ½Π½ΠΎΡ— Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„Ρ–Ρ—

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    Topicality. The search of new plant sources of biologically active substances is an actual issue for the pharmaceuticalΒ science. The feverfew (Tanacetum parthenium (L.) Schultz Bip) is one of the prospective species of the Aster family. Its chemicalΒ composition mainly consists of phenolic compounds and sesquiterpene lactones. According to the latest data of the foreignΒ sources feverfew herb phenolic compounds stipulate a prominent anti-inflammatory effect. This species is successfullyΒ used to treat the chronic inflammatory diseases of the connective tissue. Therefore, the determination of the qualitativeΒ composition and quantitative content in the samples of domestic feverfew raw material is actual.Aim. To determinate the qualitative composition and quantitative content of phenolic compounds in the feverfew herb.Materials and methods. The object was the feverfew herb collected in July 2017 on the territory of the BotanicalΒ garden of the National University of Pharmacy. The qualitative composition and quantitative content were determinatedΒ by the thin layer chromatography (TLC) and high performance liquid chromatography (HPLC) methods.Results and discussion. Chlorogenic and cichoric acids zones, luteolin and luteolin7-glucoside in comparison withtheir zones of reference standards were identified by TLC method. 12 compounds were identified and determinated by HPLCΒ method. Hydroxycinnamic acids, namely 3,5-dicaffeoylquinic acid (1.575 %), 4,5-dicaffeoylquinic acid (1.308 %) andΒ chlorogenic acid (0.784 %) were accumulated in the feverfew herb in the greatest amount. Among flavonoids, apigenin-7-glucoside (0.071 %) and kaempferol (0.041 %) prevailed.Conclusions. For the first time the qualitative composition and quantitative content in the feverfew herb were determinatedΒ by TLC and HPLC methods. The high content of the phenolic compounds in the plant raw material attests toΒ the opportunity of feverfew herb standardization by such classes as hydroxycinnamic acids and flavonoids. The data obtainedΒ attest to the perspective creating a medicine with the high anti inflammatory activity based on the feverfew herb.ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ. Поиск Π½ΠΎΠ²Ρ‹Ρ… Ρ€Π°ΡΡ‚ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… источников биологичСски Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… соСдинСний являСтся Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ Π·Π°Π΄Π°Ρ‡Π΅ΠΉ фармацСвтичСской Π½Π°ΡƒΠΊΠΈ. Одним ΠΈΠ· пСрспСктивных Π²ΠΈΠ΄ΠΎΠ² сСмСйства АстровыС являСтся ΠΏΠΈΠΆΠΌΠ°Β Π΄Π΅Π²ΠΈΡ‡ΡŒΡ (Tanacetum parthenium (L.) Schultz Bip). Π•Π΅ химичСский состав прСдставлСн прСимущСствСнно Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹ΠΌΠΈ соСдинСниями ΠΈ сСсквитСрпСновыми Π»Π°ΠΊΡ‚ΠΎΠ½Π°ΠΌΠΈ. Богласно послСдним Π΄Π°Π½Π½Ρ‹ΠΌ иностранных ΠΈΡΡ‚ΠΎΡ‡Π½ΠΈΠΊΠΎΠ²Β Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹Π΅ соСдинСния Ρ‚Ρ€Π°Π²Ρ‹ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ ΠΎΠ±ΡƒΡΠ»ΠΎΠ²Π»ΠΈΠ²Π°ΡŽΡ‚ Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½Ρ‹ΠΉ ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ эффСкт.Β Π”Π°Π½Π½Ρ‹ΠΉ Π²ΠΈΠ΄ ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½ΡΡŽΡ‚ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ хроничСских Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠΎΠ΅Π΄ΠΈΠ½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ‚ΠΊΠ°Π½ΠΈ. Π‘Π»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ, ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ качСствСнного состава ΠΈ количСствСнного содСрТания Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹Ρ… соСдинСний Π² ΠΎΠ±Ρ€Π°Π·Ρ†Π°Ρ… отСчСствСнного ΡΡ‹Ρ€ΡŒΡ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ являСтся Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ.ЦСлью Ρ€Π°Π±ΠΎΡ‚Ρ‹ Π±Ρ‹Π»ΠΎ исслСдованиС качСствСнного состава ΠΈ количСствСнного содСрТания Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹Ρ… соСдинСний Π² Ρ‚Ρ€Π°Π²Π΅ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠžΠ±ΡŠΠ΅ΠΊΡ‚ΠΎΠΌ Π±Ρ‹Π»Π° Ρ‚Ρ€Π°Π²Π° ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ заготовлСнная Π² июлС 2017 Π³. Π½Π° тСрриторииБотаничСского сада ΠΠ°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ фармацСвтичСского унивСрситСта. ΠšΠ°Ρ‡Π΅ΡΡ‚Π²Π΅Π½Π½Ρ‹ΠΉ состав ΠΈ количСствСнноС содСрТаниС исслСдовали ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ тонкослойной Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ (Π’Π‘Π₯) ΠΈ высокоэффСктивной Тидкостной Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ (Π’Π­Π–Π₯).Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ ΠΈΡ… обсуТдСниС. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π‘Π₯ ΠΈΠ΄Π΅Π½Ρ‚ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ Π·ΠΎΠ½Ρ‹ Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ Ρ…Π»ΠΎΡ€ΠΎΠ³Π΅Π½ΠΎΠ²ΠΎΠΉ ΠΈ Ρ†ΠΈΠΊΠΎΡ€ΠΈΠ΅Π²ΠΎΠΉ кислот, Π»ΡŽΡ‚Π΅ΠΎΠ»ΠΈΠ½Π°, Π»ΡŽΡ‚Π΅ΠΎΠ»ΠΈΠ½-7-Π³Π»ΠΈΠΊΠΎΠ·ΠΈΠ΄Π° Π² сравнСнии с Π·ΠΎΠ½Π°ΠΌΠΈ стандартных ΠΎΠ±Ρ€Π°Π·Ρ†ΠΎΠ². ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π­Π–Π₯Β ΠΈΠ΄Π΅Π½Ρ‚ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½ΠΎ ΠΈ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΎ содСрТаниС 12 соСдинСний. Π’ наибольшСм количСствС Π² Ρ‚Ρ€Π°Π²Π΅ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ накапливались гидроксикоричныС кислоты, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ 3,5-дикафСоилхинная (1,575 %), 4,5-дикафСоилхинная (1,308 %) ΠΈ хлорогСновая (0,784 %) кислоты. Π‘Ρ€Π΅Π΄ΠΈ Ρ„Π»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² количСствСнно ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°Π»ΠΈ Π°ΠΏΠΈΠ³Π΅Π½ΠΈΠ½-7-глюкозид (0,071 %) ΠΈ ΠΊΠ΅ΠΌΠΏΡ„Π΅Ρ€ΠΎΠ» (0,041 %).Π’Ρ‹Π²ΠΎΠ΄Ρ‹. Π’ΠΏΠ΅Ρ€Π²Ρ‹Π΅ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π‘Π₯ ΠΈ Π’Π­Π–Π₯ исслСдованы качСствСнный состав ΠΈ количСствСнноС ΡΠΎΠ΄Π΅Ρ€ΠΆΠ°Π½ΠΈΠ΅Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹Ρ… соСдинСний Π² Ρ‚Ρ€Π°Π²Π΅ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ. ВысокоС содСрТаниС Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ‹Ρ… соСдинСний Π² ΡΡ‹Ρ€ΡŒΠ΅ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΠ΅Ρ‚ ΠΎ возмоТности стандартизации Ρ‚Ρ€Π°Π²Ρ‹ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ ΠΏΠΎ Ρ‚Π°ΠΊΠΈΠΌ классам, ΠΊΠ°ΠΊ гидроксикоричныС кислоты ΠΈ Ρ„Π»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄Ρ‹. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Π΄Π°Π½Π½Ρ‹Π΅ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΡŽΡ‚ ΠΎ пСрспСктивности создания Π»Π΅ΠΊΠ°Ρ€ΡΡ‚Π²Π΅Π½Π½ΠΎΠ³ΠΎΒ Ρ€Π°ΡΡ‚ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ срСдства Π½Π° основС Ρ‚Ρ€Π°Π²Ρ‹ ΠΏΠΈΠΆΠΌΡ‹ Π΄Π΅Π²ΠΈΡ‡ΡŒΠ΅ΠΉ с высокой ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒΡŽ.ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ–ΡΡ‚ΡŒ. ΠŸΠΎΡˆΡƒΠΊ Π½ΠΎΠ²ΠΈΡ… рослинних Π΄ΠΆΠ΅Ρ€Π΅Π» Π±Ρ–ΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½ΠΎ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΈΡ… Ρ€Π΅Ρ‡ΠΎΠ²ΠΈΠ½ Ρ” Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡŽ Π·Π°Π΄Π°Ρ‡Π΅ΡŽ Ρ„Π°Ρ€ΠΌΠ°Ρ†Π΅Π²Ρ‚ΠΈΡ‡Π½ΠΎΡ— Π½Π°ΡƒΠΊΠΈ. Одним Ρ–Π· пСрспСктивних Π²ΠΈΠ΄Ρ–Π² Ρ€ΠΎΠ΄ΠΈΠ½ΠΈ Айстрові Ρ” ΠΌΠ°Ρ€ΡƒΠ½Π° Π΄Ρ–Π²ΠΎΡ‡Π° (Tanacetum parthenium (L.)Β Schultz Bip.). Π‡Ρ— Ρ…Ρ–ΠΌΡ–Ρ‡Π½ΠΈΠΉ склад прСдставлСний ΠΏΠ΅Ρ€Π΅Π²Π°ΠΆΠ½ΠΎ Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΠΌΠΈ Ρ€Π΅Ρ‡ΠΎΠ²ΠΈΠ½Π°ΠΌΠΈ Ρ‚Π° сСсквітСрпСновими Π»Π°ΠΊΡ‚ΠΎΠ½Π°ΠΌΠΈ. Π—Π° останніми Π΄Π°Π½ΠΈΠΌΠΈ Π·Π°ΠΊΠΎΡ€Π΄ΠΎΠ½Π½ΠΈΡ… Π΄ΠΆΠ΅Ρ€Π΅Π» Ρ–Π½Ρ„ΠΎΡ€ΠΌΠ°Ρ†Ρ–Ρ— Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½Ρ– сполуки Ρ‚Ρ€Π°Π²ΠΈ ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ— Π·ΡƒΠΌΠΎΠ²Π»ΡŽΡŽΡ‚ΡŒ Π²ΠΈΡ€Π°ΠΆΠ΅Π½ΠΈΠΉ ΠΏΡ€ΠΎΡ‚ΠΈΠ·Π°ΠΏΠ°Π»ΡŒΠ½ΠΈΠΉ Π΅Ρ„Π΅ΠΊΡ‚. Π”Π°Π½ΠΈΠΉ Π²ΠΈΠ΄ ΡƒΡΠΏΡ–ΡˆΠ½ΠΎ Π·Π°ΡΡ‚ΠΎΡΠΎΠ²ΡƒΡŽΡ‚ΡŒ ΠΏΡ€ΠΈ Π»Ρ–ΠΊΡƒΠ²Π°Π½Π½Ρ– Ρ…Ρ€ΠΎΠ½Ρ–Ρ‡Π½ΠΈΡ… Π·Π°ΠΏΠ°Π»ΡŒΠ½ΠΈΡ…Π·Π°Ρ…Π²ΠΎΡ€ΡŽΠ²Π°Π½ΡŒ сполучної Ρ‚ΠΊΠ°Π½ΠΈΠ½ΠΈ. ΠžΡ‚ΠΆΠ΅, дослідТСння якісного складу Ρ‚Π° ΠΊΡ–Π»ΡŒΠΊΡ–ΡΠ½ΠΎΠ³ΠΎ вмісту Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΡ… Ρ€Π΅Ρ‡ΠΎΠ²ΠΈΠ½Β Ρƒ Π·Ρ€Π°Π·ΠΊΠ°Ρ… вітчизняної сировини Ρ” Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΈΠΌ.ΠœΠ΅Ρ‚ΠΎΡŽ Ρ€ΠΎΠ±ΠΎΡ‚ΠΈ Π±ΡƒΠ»ΠΎ дослідити якісний склад Ρ– ΠΊΡ–Π»ΡŒΠΊΡ–ΡΠ½ΠΈΠΉ вміст Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΡ… сполук Ρƒ Ρ‚Ρ€Π°Π²Ρ– ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ—.ΠœΠ°Ρ‚Π΅Ρ€Ρ–Π°Π»ΠΈ Ρ‚Π° ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ. ΠžΠ±β€™Ρ”ΠΊΡ‚ΠΎΠΌ Π±ΡƒΠ»Π° Ρ‚Ρ€Π°Π²Π° ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ—, Π·Π°Π³ΠΎΡ‚ΠΎΠ²Π»Π΅Π½ΠΎΡ— Ρƒ Π»ΠΈΠΏΠ½Ρ– 2017 Ρ€. Π½Π° Ρ‚Π΅Ρ€ΠΈΡ‚ΠΎΡ€Ρ–Ρ— Π‘ΠΎΡ‚Π°Π½Ρ–Ρ‡Π½ΠΎΠ³ΠΎ саду ΠΠ°Ρ†Ρ–ΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ Ρ„Π°Ρ€ΠΌΠ°Ρ†Π΅Π²Ρ‚ΠΈΡ‡Π½ΠΎΠ³ΠΎ унівСрситСту. Якісний склад Ρ‚Π° ΠΊΡ–Π»ΡŒΠΊΡ–ΡΠ½ΠΈΠΉ вміст дослідТували мСтодом Ρ‚ΠΎΠ½ΠΊΠΎΡˆΠ°Ρ€ΠΎΠ²ΠΎΡ— Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„Ρ–Ρ— (Π’Π¨Π₯) Ρ‚Π° високоСфСктивної Ρ€Ρ–Π΄ΠΈΠ½Π½ΠΎΡ— Ρ…Ρ€ΠΎΠΌΠ°Ρ‚ΠΎΠ³Ρ€Π°Ρ„Ρ–Ρ— (Π’Π•Π Π₯).Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈ Ρ‚Π° Ρ—Ρ… обговорСння. ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π¨Π₯ Ρ–Π΄Π΅Π½Ρ‚ΠΈΡ„Ρ–ΠΊΠΎΠ²Π°Π½Ρ– Π·ΠΎΠ½ΠΈ Π½Π° Ρ€Ρ–Π²Π½Ρ– Ρ…Π»ΠΎΡ€ΠΎΠ³Π΅Π½ΠΎΠ²ΠΎΡ— Ρ‚Π° цикорієвоїкислот, Π»ΡŽΡ‚Π΅ΠΎΠ»Ρ–Π½Ρƒ, Π»ΡŽΡ‚Π΅ΠΎΠ»Ρ–Π½-7-Π³Π»Ρ–ΠΊΠΎΠ·ΠΈΠ΄Ρƒ Ρƒ порівнянні Ρ–Π· Π·ΠΎΠ½Π°ΠΌΠΈ стандартних Π·Ρ€Π°Π·ΠΊΡ–Π². ΠœΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π•Π Π₯ Ρ–Π΄Π΅Π½Ρ‚ΠΈΡ„Ρ–ΠΊΠΎΠ²Π°Π½ΠΎ Ρ‚Π° Π²ΠΈΠ·Π½Π°Ρ‡Π΅Π½ΠΎ вміст 12 сполук. Π£ Π½Π°ΠΉΠ±Ρ–Π»ΡŒΡˆΡ–ΠΉ ΠΊΡ–Π»ΡŒΠΊΠΎΡΡ‚Ρ– Ρƒ Ρ‚Ρ€Π°Π²Ρ– ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ— Π½Π°ΠΊΠΎΠΏΠΈΡ‡ΡƒΠ²Π°Π»ΠΈΡΡŒ гідроксикоричні кислоти, Π° самС 3,5-Π΄ΠΈΠΊΠ°Ρ„Π΅ΠΎΡ—Π»ΠΎΡ…Ρ–Π½Π½Π° (1,575 %), 4,5-Π΄ΠΈΠΊΠ°Ρ„Π΅ΠΎΡ—Π»ΠΎΡ…Ρ–Π½Π½Π° (1,308 %) Ρ‚Π° Ρ…Π»ΠΎΡ€ΠΎΠ³Π΅Π½ΠΎΠ²Π° (0,784 %) кислоти. Π‘Π΅Ρ€Π΅Π΄ Ρ„Π»Π°Π²ΠΎΠ½ΠΎΡ—Π΄Ρ–Π² ΠΊΡ–Π»ΡŒΠΊΡ–ΡΠ½ΠΎ ΠΏΠ΅Ρ€Π΅Π²Π°ΠΆΠ°Π»ΠΈ Π°ΠΏΡ–Π³Π΅Π½Ρ–Π½-7-глюкозид (0,071 %) Ρ‚Π° ΠΊΠ΅ΠΌΠΏΡ„Π΅Ρ€ΠΎΠ» (0,041 %).Висновки. Π’ΠΏΠ΅Ρ€ΡˆΠ΅ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π’Π¨Π₯ Ρ‚Π° Π’Π•Π Π₯ дослідТСно якісний склад Ρ‚Π° ΠΊΡ–Π»ΡŒΠΊΡ–ΡΠ½ΠΈΠΉ вміст Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΡ… сполуку Ρ‚Ρ€Π°Π²Ρ– ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ—. Високий вміст Ρ„Π΅Π½ΠΎΠ»ΡŒΠ½ΠΈΡ… Ρ€Π΅Ρ‡ΠΎΠ²ΠΈΠ½ Ρƒ сировині ΡΠ²Ρ–Π΄Ρ‡ΠΈΡ‚ΡŒ ΠΏΡ€ΠΎ ΠΌΠΎΠΆΠ»ΠΈΠ²Ρ–ΡΡ‚ΡŒ стандартизації трави ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ— Π·Π° Ρ‚Π°ΠΊΠΈΠΌΠΈ класами, як гідроксикоричні кислоти Ρ‚Π° Ρ„Π»Π°Π²ΠΎΠ½ΠΎΡ—Π΄ΠΈ. ΠžΡ‚Ρ€ΠΈΠΌΠ°Π½Ρ– Π΄Π°Π½Ρ– ΡΠ²Ρ–Π΄Ρ‡Π°Ρ‚ΡŒΒ ΠΏΡ€ΠΎ ΠΏΠ΅Ρ€ΡΠΏΠ΅ΠΊΡ‚ΠΈΠ²Π½Ρ–ΡΡ‚ΡŒ створСння Π»Ρ–ΠΊΠ°Ρ€ΡΡŒΠΊΠΎΠ³ΠΎ рослинного засобу Π½Π° основі Ρ‚Ρ€Π°Π²ΠΈ ΠΌΠ°Ρ€ΡƒΠ½ΠΈ Π΄Ρ–Π²ΠΎΡ‡ΠΎΡ— Π· високою ΠΏΡ€ΠΎΡ‚ΠΈΠ·Π°ΠΏΠ°Π»ΡŒΠ½ΠΎΡŽ Π°ΠΊΡ‚ΠΈΠ²Π½Ρ–ΡΡ‚ΡŽ
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