Nurturing the young shoots of talent: Using action research for exploration and theory building

This is an Author's Accepted Manuscript of an article published in European Early Childhood Education Research Journal, 19(4), 433-450, 2011, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/1350293X.2011.623515.This paper reports the outcomes of a set of action research projects carried out by teacher researchers in 14 local education authorities in England, working collaboratively with university tutors, over a period of three years. The common aim of all the projects was to explore practical ways of nurturing the gifts and talents of children aged four–seven years. The project was funded by the Department of Education and Skills in England as part of the government's gifted and talented programme. The project teachers felt that their understanding of issues relating to nurturing the gifts and talents of younger children was enhanced through their engagement in the project. It was possible to map the findings of the projects to the English government's National Quality Standards for gifted and talented education which include: (1) identification; (2) effective provision in the classroom; (3) enabling curriculum entitlement and choice; (4) assessment for learning; (5) engaging with community, families and beyond. The findings are also analysed within the framework of good practice in educating children in the first years of schooling. Participating practitioners felt that action research offered them a suitable methodology to explore the complexity of the topic of giftedness through cycles of planning, action and reflection and personal theory building

More insights into bar quenching. Multi-wavelength analysis of four barred galaxies

The underlying nature of the process of star formation quenching in the central regions of barred disc galaxies that is due to the action of stellar bar is not fully understood. We present a multi-wavelength study of four barred galaxies using the archival data from optical, ultraviolet, infrared, CO, and HI imaging data on star formation progression and stellar and gas distribution to better understand the process of bar quenching. We found that for three galaxies, the region between the nuclear or central sub-kiloparsec region and the end of the bar (bar region) is devoid of neutral and molecular hydrogen. While the detected neutral hydrogen is very negligible, we note that molecular hydrogen is present abundantly in the nuclear or central sub-kiloparsec regions of all four galaxies. The bar co-rotation radius is also devoid of recent star formation for three out of four galaxies. One galaxy shows significant molecular hydrogen along the bar, which might mean that the gas is still being funnelled to the centre by the action of the stellar bar. Significant star formation is also present along the bar co-rotation radius of this galaxy. The study presented here supports a scenario in which gas redistribution as a result of the action of stellar bar clears the bar region of fuel for further star formation and eventually leads to star formation quenching in the bar region.Comment: Accepted for publication in A&A. Continuation on the letter paper (arXiv:1812.04178) to appear in main journa

Assessment of myofascial pain syndrome among married female healthcare workers: a cross sectional comparative study in a tertiary care centre

Background: Myofascial pain syndrome (MPS) is common among females between ages 20-40 years. Psychosomatic and mechanical reasons are attributed as causative factors. Female health care workers (FHW) in hospitals with rapid patient turn over are vulnerable to develop MPS. Our aim was to ascertain the prevalence of MPS in married FHW working in various departments of the hospital and its association with poor sleep and work stress. Methods: We selected married FHWs in 20-50 years age group and divided them into two groups, medical and paramedical (those involved directly and indirectly with patient care respectively). MPS was diagnosed after detailed personal interview and clinical examination. Sleep duration was divided into less than 5 hours and more than 5hours. Presence of work-related stress and other medical parameters were also recorded. Results: A total of 150 medical and 150 paramedical FHWs were included in the study. Overall prevalence of MPS among FHWs was 42%, of which, medical group was 32% and paramedical was 52%. The paramedical group showed significantly higher prevalence of MPS (p: 0.02). Sleep was less than 5 hours in 29.3% of medical FHW and 13.3% of paramedical. This difference didn’t show any association to MPS (p=0.8). 38% FHW perceived excessive work stress, 40% were paramedical and 36% were medical. This didn’t correlate with prevalence of MPS (p=0.2) among them. Conclusions: Paramedical FHW experienced more MPS than medical and it was more of mechanical type and not due to work stress or sleep deprivation

Dissecting star-formation in the "Atoms-for-Peace" galaxy: Ultra-Violet Imaging Telescope observations of the post-merger galaxy NGC7252

The tidal tails of post-merger galaxies exhibit ongoing star formation far from their disks. The study of such systems can be useful for our understanding of gas condensation in diverse environments. The ongoing star formation in the tidal tails of post-merger galaxies can be directly studied from ultraviolet (UV) imaging observations. The post merger galaxy NGC7252 ("Atoms-for-Peace" galaxy) is observed with the Astrosat UV imaging telescope (UVIT) in broadband NUV and FUV filters to isolate the star forming regions in the tidal tails and study the spatial variation in star formation rates. Based on ultraviolet imaging observations, we discuss star formation regions of ages $<$ 200 Myrs in the tidal tails. We measure star formation rates in these regions and in the main body of the galaxy. The integrated star formation rate of NGC7252 (i.e., that in the galaxy and tidal tails combined) without correcting for extinction is found to be 0.81 $\pm$ 0.01 M$_{\odot}$/yr. We show that the integrated star formation rate can change by an order of magnitude if the extinction correction used in star formation rates derived from other proxies are taken into consideration. The star formation rates in the associated tidal dwarf galaxies (NGC7252E, SFR=0.02 M$_{\odot}$/yr and NGC7252NW, SFR=0.03 M$_{\odot}$/yr) are typical of dwarf galaxies in the local Universe. The spatial resolution of the UV images reveals a gradient in star formation within the tidal dwarf galaxy. The star formation rates show a dependence on the distance from the centre of the galaxy. This can be due to the different initial conditions responsible for the triggering of star formation in the gas reservoir that was expelled during the recent merger in NGC7252.Comment: Accepted for publication in Astronomy & Astrophysic

Ultra-Violet Imaging Telescope Observations of the Star-Forming Ring in NGC7252: Evidence of Possible AGN Feedback Suppressing Central Star Formation

Some post-merger galaxies are known to undergo a starburst phase that quickly depletes the gas reservoir and turns it into a red-sequence galaxy, though the details are still unclear. Here we explore the pattern of recent star formation in the central region of the post-merger galaxy NGC7252 using high resolution UV images from the UVIT on ASTROSAT. The UVIT images with 1.2 and 1.4 arcsec resolution in the FUV and NUV are used to construct a FUV-NUV colour map of the central region. The FUV-NUV pixel colour map for this canonical post-merger galaxy reveals a blue circumnuclear ring of diameter $\sim$ 10 " (3.2 kpc) with bluer patches located over the ring. Based on a comparison to single stellar population models, we show that the ring is comprised of stellar populations with ages $\lesssim$ 300 Myr, with embedded star-forming clumps of younger age ($\lesssim$ 150Myr). The suppressed star formation in the central region, along with the recent finding of a large amount of ionised gas, leads us to speculate that this ring may be connected to past feedback from a central super-massive black hole that has ionised the hydrogen gas in the central $\sim$ 4" $\sim$ 1.3 kpc.Comment: Accepted for publication in Astronomy & Astrophysics Letter

The landscape of gifted and talented education in England and Wales: How are teachers implementing policy?

This is an Author's Accepted Manuscript of an article published in Research Papers in Education, 27(2), 167-186, 2012, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/02671522.2010.509514.This paper explores the evidence relating to how primary schools are responding to the ‘gifted and talented’ initiative in England and Wales. A questionnaire survey which invited both closed and open-ended responses was carried out with a national sample of primary schools. The survey indicated an increasing proportion of coordinators, compared with a survey carried out in 1996, were identifying their gifted and talented children as well as having associated school policies. However, the survey also highlighted a number of issues which need addressing if the initiative is to achieve its objective of providing the best possible educational opportunities for children. For example, it was found that a significant number of practitioners were not aware of the existence of the National Quality Standards for gifted and talented education, provided by the UK government in 2007, and the subject-specific criteria provided by the UK’s Curriculum Authority for identification and provision have been largely ignored. The process of identifying children to be placed on the ‘gifted and talented’ register seems haphazard and based on pragmatic reasons. Analysis of teachers’ responses also revealed a range of views and theoretical positioning held by them, which have implications for classroom practice. As the ‘gifted and talented’ initiative in the UK is entering a second decade, and yet more significant changes in policy are introduced, pertinent questions need to be raised and given consideration

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in inflammation and in vascular biology. The human family includes 19 members that can be sub-grouped on the basis of their known substrates, namely the aggrecanases or proteoglycanases (ADAMTS1, 4, 5, 8, 9, 15 and 20), the procollagen N-propeptidases (ADAMTS2, 3 and 14), the cartilage oligomeric matrix protein-cleaving enzymes (ADAMTS7 and 12), the von-Willebrand Factor proteinase (ADAMTS13) and a group of orphan enzymes (ADAMTS6, 10, 16, 17, 18 and 19). Control of the structure and function of the extracellular matrix (ECM) is a central theme of the biology of the ADAMTS, as exemplified by the actions of the procollagen-N-propeptidases in collagen fibril assembly and of the aggrecanases in the cleavage or modification of ECM proteoglycans. Defects in certain family members give rise to inherited genetic disorders, while the aberrant expression or function of others is associated with arthritis, cancer and cardiovascular disease. In particular, ADAMTS4 and 5 have emerged as therapeutic targets in arthritis. Multiple ADAMTSs from different sub-groupings exert either positive or negative effects on tumorigenesis and metastasis, with both metalloproteinase-dependent and -independent actions known to occur. The basic ADAMTS structure comprises a metalloproteinase catalytic domain and a carboxy-terminal ancillary domain, the latter determining substrate specificity and the localization of the protease and its interaction partners; ancillary domains probably also have independent biological functions. Focusing primarily on the aggrecanases and proteoglycanases, this review provides a perspective on the evolution of the ADAMTS family, their links with developmental and disease mechanisms, and key questions for the future

Gene expression and matrix turnover in overused and damaged tendons

Chronic, painful conditions affecting tendons, frequently known as tendinopathy, are very common types of sporting injury. The tendon extracellular matrix is substantially altered in tendinopathy, and these changes are thought to precede and underlie the clinical condition. The tendon cell response to repeated minor injuries or “overuse” is thought to be a major factor in the development of tendinopathy. Changes in matrix turnover may also be effected by the cellular response to physical load, altering the balance of matrix turnover and changing the structure and composition of the tendon. Matrix turnover is relatively high in tendons exposed to high mechanical demands, such as the supraspinatus and Achilles, and this is thought to represent either a repair or tissue maintenance function. Metalloproteinases are a large family of enzymes capable of degrading all of the tendon matrix components, and these are thought to play a major role in the degradation of matrix during development, adaptation and repair. It is proposed that some metalloproteinase enzymes are required for the health of the tendon, and others may be damaging, leading to degeneration of the tissue. Further research is required to investigate how these enzyme activities are regulated in tendon and altered in tendinopathy. A profile of all the metalloproteinases expressed and active in healthy and degenerate tendon is required and may lead to the development of new drug therapies for these common and debilitating sports injuries

Serum Islet Cell Autoantibodies During Interferon α Treatment in Patients With HCV-Genotype 4 Chronic Hepatitis

Chronic hepatitis C virus (HCV) infection is a leading cause of end-stage liver disease worldwide and HCV genotype 4 (HCV4) is predominant in African and Middle Eastern countries. It is well established that interferon-α (IFNa) treatment for HCV may trigger serum autoantibodies against pancreatic islet cells (ICA) in a subgroup of patients. Available data on the incidence of ICA during IFNa therapy for chronic HCV4 infection are not conclusive. We investigated the appearance of ICA in 40 naïve Egyptian patients (38 males, 32 ± 6 years) with histologically defined chronic HCV4 infection undergoing IFNa treatment at a dose of 9-million U/week for 24 weeks. Serum samples were collected at baseline and following IFNa therapy and ICA were detected using indirect immunofluorescence. Baseline evaluation indicated that 2/40 (5%) patients had detectable serum ICA. After the completion of the treatment scheme, 12/38 (32%) previously ICA negative patients became ICA positive; however, no patient developed impaired glucose tolerance (IGT) or diabetes during follow-up. In conclusion, we submit that IFNa treatment for chronic hepatitis C (CHC) may induce serum ICA in one-third of Egyptian patients with HCV4. These autoantibodies, however, do not lead to alterations in glucose metabolism